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Fingerprint Dive into the research topics where Jian Xu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Globins Medicine & Life Sciences
Fetal Hemoglobin Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Genes Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Polycomb Repressive Complex 2 Medicine & Life Sciences
Erythroid Cells Medicine & Life Sciences

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Research Output 2007 2019

  • 3462 Citations
  • 29 h-Index
  • 44 Article
  • 2 Letter
  • 1 Conference contribution
  • 1 Comment/debate

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, P. B., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access
Carbamyl Phosphate
Lung Neoplasms
DNA
pyrimidine
phosphorylethanolamine
2 Citations (Scopus)

Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation

Gu, Z., Liu, Y., Cai, F., Patrick, M., Zmajkovic, J., Cao, H., Zhang, Y., Tasdogan, A., Chen, M., Qi, L., Liu, X., Li, K., Lyu, J., Dickerson, K. E., Chen, W., Ni, M., Merritt, M. E., Morrison, S. J., Skoda, R. C., DeBerardinis, R. J. & 1 others, Xu, J., Sep 1 2019, In : Cancer discovery. 9, 9, p. 1228-1247 20 p.

Research output: Contribution to journalArticle

Branched Chain Amino Acids
Epigenomics
Neoplasms
Leukemia
Myeloid Leukemia
1 Citation (Scopus)

CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9

Liu, X., Zhang, Y., Chen, Y., Li, M., Shao, Z., Zhang, M. Q. & Xu, J., Jul 1 2018, In : Current Protocols in Molecular Biology. 123, 1, e64.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Chromatin
Guide RNA
Proteins
Genome
36 Citations (Scopus)

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

Liu, N., Hargreaves, V. V., Zhu, Q., Kurland, J. V., Hong, J., Kim, W., Sher, F., Macias-Trevino, C., Rogers, J. M., Kurita, R., Nakamura, Y., Yuan, G. C., Bauer, D. E., Xu, J., Bulyk, M. L. & Orkin, S. H., Apr 5 2018, In : Cell. 173, 2, p. 430-442.e17

Research output: Contribution to journalArticle

Globins
Hemoglobins
Switches
Fetal Hemoglobin
Protein Binding
21 Citations (Scopus)

Dissecting super-enhancer hierarchy based on chromatin interactions

Huang, J., Li, K., Cai, W., Liu, X., Zhang, Y., Orkin, S. H., Xu, J. & Yuan, G. C., Dec 1 2018, In : Nature Communications. 9, 1, 943.

Research output: Contribution to journalArticle

Histone Code
chromatin
Inborn Genetic Diseases
hubs
Regulator Genes