Research Output per year
Research Output 2007 2019
2019
Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)
Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, , May 16 2019, In : Nature. 569, 7756, p. E4Research output: Contribution to journal › Comment/debate
Open Access
Carbamyl Phosphate
Lung Neoplasms
DNA
pyrimidine
phosphorylethanolamine
2
Citations
(Scopus)
Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Gu, Z., Liu, Y., Cai, F., Patrick, M., Zmajkovic, J., Cao, H., Zhang, Y., Tasdogan, A., Chen, M., Qi, L., Liu, X., Li, K., Lyu, J., Dickerson, K. E., Chen, W., Ni, M., Merritt, M. E., Morrison, S. J., Skoda, R. C., DeBerardinis, R. J. & 1 others, , Sep 1 2019, In : Cancer discovery. 9, 9, p. 1228-1247 20 p.Research output: Contribution to journal › Article
Branched Chain Amino Acids
Epigenomics
Neoplasms
Leukemia
Myeloid Leukemia
MAP: model-based analysis of proteomic data to detect proteins with significant abundance changes
Li, M., Tu, S., Li, Z., Tan, F., Liu, J., Wang, Q., Zhang, Y., Xu, J., Zhang, Y., Zhou, F. & Shao, Z., Dec 1 2019, In : Cell Discovery. 5, 1, 40.Research output: Contribution to journal › Article
Open Access
Proteomics
Data structures
Proteins
Stem cells
Isotope Labeling
2018
1
Citation
(Scopus)
CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9
Liu, X., Zhang, Y., Chen, Y., Li, M., Shao, Z., Zhang, M. Q. & Xu, J., Jul 1 2018, In : Current Protocols in Molecular Biology. 123, 1, e64.Research output: Contribution to journal › Article
Clustered Regularly Interspaced Short Palindromic Repeats
Chromatin
Guide RNA
Proteins
Genome
36
Citations
(Scopus)
Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch
Liu, N., Hargreaves, V. V., Zhu, Q., Kurland, J. V., Hong, J., Kim, W., Sher, F., Macias-Trevino, C., Rogers, J. M., Kurita, R., Nakamura, Y., Yuan, G. C., Bauer, D. E., Xu, J., Bulyk, M. L. & Orkin, S. H., Apr 5 2018, In : Cell. 173, 2, p. 430-442.e17Research output: Contribution to journal › Article
Globins
Hemoglobins
Switches
Fetal Hemoglobin
Protein Binding
21
Citations
(Scopus)
Dissecting super-enhancer hierarchy based on chromatin interactions
Huang, J., Li, K., Cai, W., Liu, X., Zhang, Y., Orkin, S. H., Xu, J. & Yuan, G. C., Dec 1 2018, In : Nature Communications. 9, 1, 943.Research output: Contribution to journal › Article
Histone Code
chromatin
Inborn Genetic Diseases
hubs
Regulator Genes
2
Citations
(Scopus)
GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism
Tanimura, N., Liao, R., Wilson, G. M., Dent, M. R., Cao, M., Burstyn, J. N., Hematti, P., Liu, X., Zhang, Y., Zheng, Y., Keles, S., Xu, J., Coon, J. J. & Bresnick, E. H., Sep 10 2018, In : Developmental Cell. 46, 5, p. 581-594.e4Research output: Contribution to journal › Article
Heme
Zinc
Metals
Erythrocytes
Anemia
1
Citation
(Scopus)
Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters
Sun, H., Wang, J., Gong, Z., Yao, J., Wang, Y., Xu, J., Yuan, G. C., Zhang, Y. & Shao, Z., Dec 1 2018, In : Cell Discovery. 4, 1, 38.Research output: Contribution to journal › Letter
Epigenomics
Transcription Factors
Genes
12
Citations
(Scopus)
Regulation of embryonic haematopoietic multipotency by EZH1
Vo, L. T., Kinney, M. A., Liu, X., Zhang, Y., Barragan, J., Sousa, P. M., Jha, D. K., Han, A., Cesana, M., Shao, Z., North, T. E., Orkin, S. H., Doulatov, S., Xu, J. & Daley, G. Q., Jan 25 2018, In : Nature. 553, 7689, p. 506-510 5 p.Research output: Contribution to journal › Article
Hematopoietic Stem Cells
Mammalian Embryo
Yolk Sac
Embryonic Structures
Mesonephros
2017
51
Citations
(Scopus)
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, , Jun 1 2017, In : Nature. 546, 7656, p. 168-172 5 p.Research output: Contribution to journal › Article
Carbamyl Phosphate
Ligases
Lung Neoplasms
DNA
Ammonia
56
Citations
(Scopus)
In Situ Capture of Chromatin Interactions by Biotinylated dCas9
Liu, X., Zhang, Y., Chen, Y., Li, M., Zhou, F., Li, K., Cao, H., Ni, M., Liu, Y., Gu, Z., Dickerson, K. E., Xie, S., Hon, G. C., Xuan, Z., Zhang, M. Q., Shao, Z. & Xu, J., Aug 24 2017, In : Cell. 170, 5, p. 1028-1043.e19Research output: Contribution to journal › Article
Chromatin
Clustered Regularly Interspaced Short Palindromic Repeats
Purification
Genes
Guide RNA
30
Citations
(Scopus)
Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation
Liu, X., Zhang, Y., Ni, M., Cao, H., Signer, R. A. J., Li, D., Li, M., Gu, Z., Hu, Z., Dickerson, K. E., Weinberg, S. E., Chandel, N. S., Deberardinis, R. J., Zhou, F., Shao, Z. & Xu, J., May 31 2017, In : Nature Cell Biology. 19, 6, p. 626-638 13 p.Research output: Contribution to journal › Article
Erythropoiesis
Protein Biosynthesis
Organelle Biogenesis
Mitochondria
Hematopoietic Stem Cells
2
Citations
(Scopus)
Temporal dynamics of cardiac hypertrophic growth in response to pressure overload
Wang, Y., Zhang, Y., Ding, G., May, H. I., Xu, J., Gillette, T. G., Wang, H. & Wang, Z. V., Dec 1 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 313, 6, p. H1119-H1129Research output: Contribution to journal › Article
Pressure
Growth
Puromycin
Cardiac Myocytes
Muscle Cells
56
Citations
(Scopus)
The mitochondrial respiratory chain is essential for haematopoietic stem cell function
Ansó, E., Weinberg, S. E., Diebold, L. P., Thompson, B. J., Malinge, S., Schumacker, P. T., Liu, X., Zhang, Y., Shao, Z., Steadman, M., Marsh, K. M., Xu, J., Crispino, J. D. & Chandel, N. S., May 31 2017, In : Nature Cell Biology. 19, 6, p. 614-625 12 p.Research output: Contribution to journal › Article
Electron Transport
Hematopoietic Stem Cells
Fetal Stem Cells
Respiration
Adult Stem Cells
2016
21
Citations
(Scopus)
Bcl11a Deficiency Leads to Hematopoietic Stem Cell Defects with an Aging-like Phenotype
Luc, S., Huang, J., McEldoon, J. L., Somuncular, E., Li, D., Rhodes, C., Mamoor, S., Hou, S., Xu, J. & Orkin, S. H., Sep 20 2016, In : Cell Reports. 16, 12, p. 3181-3194 14 p.Research output: Contribution to journal › Article
B-Cell Lymphoma
Hematopoietic Stem Cells
Stem cells
Aging of materials
Phenotype
76
Citations
(Scopus)
Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis
Huang, J., Liu, X., Li, D., Shao, Z., Cao, H., Zhang, Y., Trompouki, E., Bowman, T. V., Zon, L. I., Yuan, G. C., Orkin, S. H. & Xu, J., Jan 11 2016, In : Developmental Cell. 36, 1, p. 9-23 15 p.Research output: Contribution to journal › Article
Hematopoiesis
Transcription
Hematopoietic Stem Cells
Clustered Regularly Interspaced Short Palindromic Repeats
Switches
70
Citations
(Scopus)
Gene regulation: Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin
Masuda, T., Wang, X., Maeda, M., Canver, M. C., Sher, F., Funnell, A. P. W., Fisher, C., Suciu, M., Martyn, G. E., Norton, L. J., Zhu, C., Kurita, R., Nakamura, Y., Xu, J., Higgs, D. R., Crossley, M., Bauer, D. E., Orkin, S. H., Kharchenko, P. V. & Maeda, T., Jan 15 2016, In : Science. 351, 6270, p. 285-289 5 p.Research output: Contribution to journal › Article
Fetal Hemoglobin
Globins
Transcription Factors
Hemoglobinopathies
Genes
7
Citations
(Scopus)
Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease
Nwankwo, J. O., Lei, J., Xu, J., Rivera, A., Gupta, K. & Chishti, A. H., Sep 30 2016, In : Haematologica. 101, 10, p. e397-e400Research output: Contribution to journal › Letter
Calpain
Sickle Cell Anemia
Pain
43
Citations
(Scopus)
Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration
Sun, X., Chuang, J. C., Kanchwala, M., Wu, L., Celen, C., Li, L., Liang, H., Zhang, S., Maples, T., Nguyen, L. H., Wang, S. C., Signer, R. A. J., Sorouri, M., Nassour, I., Liu, X., Xu, J., Wu, M., Zhao, Y., Kuo, Y. C., Wang, Z. & 2 others, , Apr 7 2016, In : Cell Stem Cell. 18, 4, p. 456-466 11 p.Research output: Contribution to journal › Article
Regeneration
Wounds and Injuries
Chromatin Assembly and Disassembly
Epigenomics
Chromatin
2015
55
Citations
(Scopus)
Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions
Xu, J., Shao, Z., Li, D., Xie, H., Kim, W., Huang, J., Taylor, J. E., Pinello, L., Glass, K., Jaffe, J. D., Yuan, G. C. & Orkin, S. H., Jan 22 2015, In : Molecular Cell. 57, 2, p. 304-316 13 p.Research output: Contribution to journal › Article
Polycomb Repressive Complex 2
GATA Transcription Factors
Blood Cells
Stem Cells
Proteomics
25
Citations
(Scopus)
PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells
Das, P. P., Hendrix, D. A., Apostolou, E., Buchner, A. H., Canver, M. C., Beyaz, S., Ljuboja, D., Kuintzle, R., Kim, W., Karnik, R., Shao, Z., Xie, H., Xu, J., De Los Angeles, A., Zhang, Y., Choe, J., Jun, D. L. J., Shen, X., Gregory, R. I., Daley, G. Q. & 5 others, , Sep 1 2015, In : Cell Reports. 12, 9, p. 1456-1470 15 p., 1953.Research output: Contribution to journal › Article
Polycomb Repressive Complex 2
DNA Methylation
Stem cells
Mothers
Methyltransferases
13
Citations
(Scopus)
Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology
Ishikawa, Y., Maeda, M., Pasham, M., Aguet, F., Tacheva-Grigorova, S. K., Masuda, T., Yi, H., Lee, S. U., Xu, J., Teruya-Feldstein, J., Ericsson, M., Mullally, A., Heuser, J., Kirchhausen, T. & Maeda, T., 2015, In : Haematologica. 100, 4, p. 439-451 13 p.Research output: Contribution to journal › Article
Vesicular Transport Adaptor Proteins
Polycythemia Vera
Hematopoiesis
Endocytosis
Transferrin Receptors
2014
36
Citations
(Scopus)
Analysis of chromatin-state plasticity identifies cell-type-specific regulators of H3K27me3 patterns
Pinello, L., Xu, J., Orkin, S. H. & Yuan, G. C., Jan 21 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 3Research output: Contribution to journal › Article
Chromatin
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
CpG Islands
Genome
Erythropoiesis
15
Citations
(Scopus)
GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia
Maroz, A., Stachorski, L., Emmrich, S., Reinhardt, K., Xu, J., Shao, Z., Käbler, S., Dertmann, T., Hitzler, J., Roberts, I., Vyas, P., Juban, G., Hennig, C., Hansen, G., Li, Z., Orkin, S., Reinhardt, D. & Klusmann, J. H., 2014, In : Leukemia. 28, 6, p. 1259-1270 12 p.Research output: Contribution to journal › Article
Down Syndrome
Eosinophils
Eosinophilia
Hematopoietic Stem Cells
Mutation
110
Citations
(Scopus)
Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production
Li, Y., Esain, V., Teng, L., Xu, J., Kwan, W., Frost, I. M., Yzaguirre, A. D., Cai, X., Cortes, M., Maijenburg, M. W., Tober, J., Dzierzak, E., Orkin, S. H., Tan, K., North, T. E. & Speck, N. A., Dec 1 2014, In : Genes and Development. 28, 23, p. 2597-2612 16 p.Research output: Contribution to journal › Article
Embryonic Stem Cells
Hematopoietic Stem Cells
Mesonephros
Interferons
Gonads
153
Citations
(Scopus)
Polycomb repressive complex 2 regulates normal hematopoietic stem cell function in a developmental-stage-specific manner
Xie, H., Xu, J., Hsu, J. H., Nguyen, M., Fujiwara, Y., Peng, C. & Orkin, S. H., Jan 2 2014, In : Cell Stem Cell. 14, 1, p. 68-80 13 p.Research output: Contribution to journal › Article
Polycomb Repressive Complex 2
Hematopoietic Stem Cells
Genes
Adult Stem Cells
Neoplastic Stem Cells
2013
282
Citations
(Scopus)
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
Bauer, D. E., Kamran, S. C., Lessard, S., Xu, J., Fujiwara, Y., Lin, C., Shao, Z., Canver, M. C., Smith, E. C., Pinello, L., Sabo, P. J., Vierstra, J., Voit, R. A., Yuan, G. C., Porteus, M. H., Stamatoyannopoulos, J. A., Lettre, G. & Orkin, S. H., 2013, In : Science. 342, 6155, p. 253-257 5 p.Research output: Contribution to journal › Article
Fetal Hemoglobin
Genome-Wide Association Study
Genome
Hemoglobinopathies
Essential Genes
91
Citations
(Scopus)
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A
Xu, J., Bauer, D. E., Kerenyi, M. A., Vo, T. D., Hou, S., Hsu, Y. J., Yao, H., Trowbridge, J. J., Mandel, G. & Orkin, S. H., Apr 16 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 16, p. 6518-6523 6 p.Research output: Contribution to journal › Article
Fetal Hemoglobin
Co-Repressor Proteins
Globins
Erythroid Cells
Methyltransferases
143
Citations
(Scopus)
Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire
Guo, G., Luc, S., Marco, E., Lin, T. W., Peng, C., Kerenyi, M. A., Beyaz, S., Kim, W., Xu, J., Das, P. P., Neff, T., Zou, K., Yuan, G. C. & Orkin, S. H., Oct 3 2013, In : Cell Stem Cell. 13, 4, p. 492-505 14 p.Research output: Contribution to journal › Article
Single-Cell Analysis
Cell Differentiation
Hematopoietic System
Hematopoietic Stem Cells
Acute Myeloid Leukemia
2012
98
Citations
(Scopus)
Combinatorial Assembly of Developmental Stage-Specific Enhancers Controls Gene Expression Programs during Human Erythropoiesis
Xu, J., Shao, Z., Glass, K., Bauer, D. E., Pinello, L., Van Handel, B., Hou, S., Stamatoyannopoulos, J. A., Mikkola, H. K. A., Yuan, G. C. & Orkin, S. H., Oct 16 2012, In : Developmental Cell. 23, 4, p. 796-811 16 p.Research output: Contribution to journal › Article
Erythropoiesis
Gene expression
Gene Expression
Chromatin
Transcriptome
58
Citations
(Scopus)
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number
Sankaran, V. G., Ludwig, L. S., Sicinska, E., Xu, J., Bauer, D. E., Eng, J. C., Patterson, H. C., Metcalf, R. A., Natkunam, Y., Orkin, S. H., Sicinski, P., Lander, E. S. & Lodish, H. F., Sep 15 2012, In : Genes and Development. 26, 18, p. 2075-2087 13 p.Research output: Contribution to journal › Article
Cyclin D3
Erythrocyte Count
Cell Cycle
Erythrocytes
Erythroid Cells
9
Citations
(Scopus)
Designing an enhancer landscape
Xu, J. & Smale, S. T., Nov 21 2012, In : Cell. 151, 5, p. 929-931 3 p.Research output: Contribution to journal › Article
T-cells
Cell Lineage
T-Lymphocytes
17
Citations
(Scopus)
Generation of a genomic reporter assay system for analysis of γ- and β-globin gene regulation
Chan, K. S. K., Xu, J., Wardan, H., McColl, B., Orkin, S. & Vadolas, J., Apr 2012, In : FASEB Journal. 26, 4, p. 1736-1744 9 p.Research output: Contribution to journal › Article
Globins
Systems Analysis
Gene expression
Assays
Genes
2011
100
Citations
(Scopus)
A functional element necessary for fetal hemoglobin silencing
Sankaran, V. G., Xu, J., Byron, R., Greisman, H. A., Fisher, C., Weatherall, D. J., Sabath, D. E., Groudine, M., Orkin, S. H., Premawardhena, A. & Bender, M. A., Sep 1 2011, In : New England Journal of Medicine. 365, 9, p. 807-814 8 p.Research output: Contribution to journal › Article
Fetal Hemoglobin
Globins
Intergenic DNA
Trans-Activators
Thalassemia
178
Citations
(Scopus)
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing
Xu, J., Peng, C., Sankaran, V. G., Shao, Z., Esrick, E. B., Chong, B. G., Ippolito, G. C., Fujiwara, Y., Ebert, B. L., Tucker, P. W. & Orkin, S. H., Nov 18 2011, In : Science. 334, 6058, p. 993-996 4 p.Research output: Contribution to journal › Article
Fetal Hemoglobin
Sickle Cell Anemia
Thalassemia
Globins
Transgenic Mice
13
Citations
(Scopus)
Role of ZBP-89 in human globin gene regulation and erythroid differentiation
Woo, A. J., Kim, J., Xu, J., Huang, H. & Cantor, A. B., Sep 29 2011, In : Blood. 118, 13, p. 3684-3693 10 p.Research output: Contribution to journal › Article
Globins
Gene expression
Genes
Gene Expression
Histones
1
Citation
(Scopus)
The erythroid/myeloid lineage fate paradigm takes a new player
Xu, J. & Orkin, S. H., Mar 16 2011, In : EMBO Journal. 30, 6, p. 983-985 3 p.Research output: Contribution to journal › Article
Zebrafish
Chromatin
Blood
Transcription Factors
Embryonic Structures
2010
123
Citations
(Scopus)
Advances in the understanding of haemoglobin switching: Review
Sankaran, V. G., Xu, J. & Orkin, S. H., Apr 2010, In : British Journal of Haematology. 149, 2, p. 181-194 14 p.Research output: Contribution to journal › Article
Hemoglobins
Cercopithecidae
Developmental Genes
Fetal Hemoglobin
Hemoglobinopathies
16
Citations
(Scopus)
Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP)
Snow, J. W., Kim, J., Currie, C. R., Xu, J. & Orkin, S. H., Sep 3 2010, In : Journal of Biological Chemistry. 285, 36, p. 28064-28075 12 p.Research output: Contribution to journal › Article
Sumoylation
Post Translational Protein Processing
Mi-2 Nucleosome Remodeling and Deacetylase Complex
GATA1 Transcription Factor
Genes
28
Citations
(Scopus)
Transcriptional silencing of fetal hemoglobin by BCL11A
Sankaran, V. G., Xu, J. & Orkin, S. H., Aug 2010, Annals of the New York Academy of Sciences. Vol. 1202. p. 64-68 5 p. (Annals of the New York Academy of Sciences; vol. 1202).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Fetal Hemoglobin
Globins
Thalassemia
Genes
Switch Genes
206
Citations
(Scopus)
Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6
Xu, J., Sankaran, V. G., Ni, M., Menne, T. F., Puram, R. V., Kim, W. & Orkin, S. H., Apr 15 2010, In : Genes and Development. 24, 8, p. 783-789 7 p.Research output: Contribution to journal › Article
Globins
Developmental Genes
SOXD Transcription Factors
Hemoglobins
Locus Control Region
2009
243
Citations
(Scopus)
Developmental and species-divergent globin switching are driven by BCL11A
Sankaran, V. G., Xu, J., Ragoczy, T., Ippolito, G. C., Walkley, C. R., Maika, S. D., Fujiwara, Y., Ito, M., Groudine, M., Bender, M. A., Tucker, P. W. & Orkin, S. H., Aug 27 2009, In : Nature. 460, 7259, p. 1093-1097 5 p.Research output: Contribution to journal › Article
Globins
Genes
Trans-Activators
Gene Expression
Genome-Wide Association Study
37
Citations
(Scopus)
Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150
Papathanasiou, P., Attema, J. L., Karsunky, H., Jian, X., Smale, S. T. & Weissman, I. L., Oct 2009, In : Stem Cells. 27, 10, p. 2498-2508 11 p.Research output: Contribution to journal › Article
Hematopoietic Stem Cells
Liver
Bone Marrow
Chromatin
Stem Cells
122
Citations
(Scopus)
Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells
Xu, J., Watts, J. A., Pope, S. D., Gadue, P., Kamps, M., Plath, K., Zaret, K. S. & Smale, S. T., Dec 15 2009, In : Genes and Development. 23, 24, p. 2824-2838 15 p.Research output: Contribution to journal › Article
Induced Pluripotent Stem Cells
Mental Competency
Transcription Factors
Embryonic Stem Cells
Genes
2008
462
Citations
(Scopus)
Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A
Sankaran, V. G., Menne, T. F., Xu, J., Akie, T. E., Lettre, G., Van Handel, B., Mikkola, H. K. A., Hirschhorn, J. N., Cantor, A. B. & Orkin, S. H., Dec 19 2008, In : Science. 322, 5909, p. 1839-1842 4 p.Research output: Contribution to journal › Article
Fetal Hemoglobin
Erythroid Cells
Globins
Thalassemia
Genetic Association Studies
103
Citations
(Scopus)
Pioneer factors, genetic competence, and inductive signaling: Programming liver and pancreas progenitors from the endoderm
Zaret, K. S., Watts, J., Xu, J., Wandzioch, E., Smale, S. T. & Sekiya, T., 2008, In : Cold Spring Harbor Symposia on Quantitative Biology. 73, p. 119-126 8 p.Research output: Contribution to journal › Article
Endoderm
Liver
Mental Competency
Chromatin
Pancreas
2007
35
Citations
(Scopus)
An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment
Zhou, L., Nazarian, A. A., Xu, J., Tantin, D., Corcoran, L. M. & Smale, S. T., Apr 2007, In : Molecular and Cellular Biology. 27, 7, p. 2698-2712 15 p.Research output: Contribution to journal › Article
Chromatin
Macrophages
Deoxyribonuclease I
Transfection
Hypersensitivity
115
Citations
(Scopus)
Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis
Attema, J. L., Papathanasiou, P., Forsberg, E. C., Xu, J., Smale, S. T. & Weissman, I. L., Jul 24 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 30, p. 12371-12376 6 p.Research output: Contribution to journal › Article
Hematopoietic Stem Cells
Epigenomics
Cell Differentiation
Histone Code
Stem Cells
88
Citations
(Scopus)
Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells
Xu, J., Pope, S. D., Jazirehi, A. R., Attema, J. L., Papathanasiou, P., Watts, J. A., Zaret, K. S., Weissman, I. L. & Smale, S. T., Jul 24 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 30, p. 12377-12382 6 p.Research output: Contribution to journal › Article
Embryonic Stem Cells
Histone Code
Genes
Chromatin Assembly and Disassembly
Chromatin Immunoprecipitation