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Research Output 1992 2019

2019

Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis

Caron, A., Reynolds, R. P., Castorena, C. M., Michael, N. J., Lee, C. E., Lee, S., Berdeaux, R., Scherer, P. E. & Elmquist, J. K., Jan 1 2019, In : Molecular Metabolism.

Research output: Contribution to journalArticle

Open Access
Adipocytes
Lipolysis
Adipose Tissue
Homeostasis
Sympathetic Nervous System

Erratum: Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction (Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction (2011) 14(4) (453–465), (S1550413111003391), (10.1016/j.cmet.2011.08.009))

Xu, Y., Nedungadi, T. P., Zhu, L., Sobhani, N., Irani, B. G., Davis, K. E., Zhang, X., Zou, F., Gent, L. M., Hahner, L. D., Khan, S. A., Elias, C. F., Elmquist, J. K. & Clegg, D. J., May 7 2019, In : Cell Metabolism. 29, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Reproduction
Estrogens
Homeostasis
Neurons
3 Citations (Scopus)

NURR1 activation in skeletal muscle controls systemic energy homeostasis

Amoasii, L., Sanchez-Ortiz, E., Fujikawa, T., Elmquist, J. K., Bassel-Duby, R. S. & Olson, E. N., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11299-11308 10 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Homeostasis
Glucose
Nuclear Receptor Subfamily 4, Group A, Member 2
Orphan Nuclear Receptors
4 Citations (Scopus)

Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy

Zhao, S., Zhu, Y., Schultz, R. D., Li, N., He, Z., Zhang, Z., Caron, A., Zhu, Q., Sun, K., Xiong, W., Deng, H., Sun, J., Deng, Y., Kim, M., Lee, C. E., Gordillo, R., Liu, T., Odle, A. K., Childs, G. V., Zhang, N. & 5 others, Kusminski, C. M., Elmquist, J. K., Williams, K. W., An, Z. & Scherer, P. E., Oct 1 2019, In : Cell Metabolism. 30, 4, p. 706-719.e6

Research output: Contribution to journalArticle

Leptin
Weight Loss
Insulin
Obesity
Energy Metabolism
7 Citations (Scopus)

Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver

Cappel, D. A., Deja, S., Duarte, J. A. G., Kucejova, B., Iñigo, M., Fletcher, J. A., Fu, X., Berglund, E. D., Liu, T., Elmquist, J. K., Hammer, S., Mishra, P., Browning, J. D. & Burgess, S. C., Jun 4 2019, In : Cell Metabolism. 29, 6, p. 1291-1305.e8

Research output: Contribution to journalArticle

Pyruvate Carboxylase
Oxidation-Reduction
Antioxidants
Liver
Gluconeogenesis
2018
5 Citations (Scopus)

Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

Mountjoy, K. G., Caron, A., Hubbard, K., Shome, A., Grey, A. C., Sun, B., Bould, S., Middleditch, M., Pontré, B., McGregor, A., Harris, P. W. R., Kowalczyk, R., Brimble, M. A., Botha, R., Tan, K. M. L., Piper, S. J., Buchanan, C., Lee, S., Coll, A. P. & Elmquist, J. K., Mar 1 2018, In : Molecular Metabolism. 9, p. 207-216 10 p.

Research output: Contribution to journalArticle

Melanocyte-Stimulating Hormones
Pro-Opiomelanocortin
Receptor, Melanocortin, Type 4
Peptides
Receptor, Melanocortin, Type 2
8 Citations (Scopus)

Ghrelin mediates exercise endurance and the feeding response post-exercise

Mani, B. K., Castorena, C. M., Osborne-Lawrence, S., Vijayaraghavan, P., Metzger, N. P., Elmquist, J. K. & Zigman, J. M., Jan 1 2018, (Accepted/In press) In : Molecular Metabolism.

Research output: Contribution to journalArticle

Ghrelin
Ghrelin Receptor
Eating
Blood Glucose
Exercise
6 Citations (Scopus)

Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease

Jia, L., Chang, X., Qian, S., Liu, C., Lord, C. C., Ahmed, N., Lee, C. E., Lee, S., Gautron, L., Mitchell, M. C., Horton, J. D., Scherer, P. E. & Elmquist, J. K., Aug 1 2018, In : Molecular Metabolism. 14, p. 121-129 9 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Fatty Liver
Liver Diseases
Hepatocytes
Alcohols
26 Citations (Scopus)

Leptin and brain-adipose crosstalks

Caron, A., Lee, S., Elmquist, J. K. & Gautron, L., Feb 16 2018, In : Nature Reviews Neuroscience. 19, 3, p. 153-165 13 p.

Research output: Contribution to journalReview article

Leptin
Brain
White Adipose Tissue
Brown Adipose Tissue
Thermogenesis
14 Citations (Scopus)

POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels

Caron, A., Lemko, H. M. D., Castorena, C. M., Fujikawa, T., Lee, S., Lord, C. C., Ahmed, N., Lee, C. E., Holland, W. L., Liu, C. & Elmquist, J. K., Mar 12 2018, In : eLife. 7, e33710.

Research output: Contribution to journalArticle

Leptin Receptors
Pro-Opiomelanocortin
Leptin
Neurons
Fasting
2017
29 Citations (Scopus)

An adipo-biliary-uridine axis that regulates energy homeostasis

Deng, Y., Wang, Z., Gordillo, R., An, Y., Zhang, C., Liang, Q., Yoshino, J., Cautivo, K. M., De Brabander, J. K., Elmquist, J. K., Horton, J. D., Hill, J. A., Klein, S. & Scherer, P. E., Mar 17 2017, In : Science. 355, 6330, eaaf5375.

Research output: Contribution to journalArticle

Uridine
Homeostasis
Fasting
Body Temperature Regulation
Leptin
7 Citations (Scopus)

Brain nuclear receptors and body weight regulation

Xu, Y., O'Malley, B. W. & Elmquist, J. K., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1172-1180 9 p.

Research output: Contribution to journalReview article

Cytoplasmic and Nuclear Receptors
Body Weight
Brain
Homeostasis
Neural Pathways
4 Citations (Scopus)

Nav1.8 neurons are involved in limiting acute phase responses to dietary fat

Udit, S., Burton, M., Rutkowski, J. M., Lee, S., Bookout, A. L., Scherer, P. E., Elmquist, J. K. & Gautron, L., 2017, (Accepted/In press) In : Molecular Metabolism.

Research output: Contribution to journalArticle

Acute-Phase Reaction
Dietary Fats
Afferent Neurons
Sensory Receptor Cells
Neurons
10 Citations (Scopus)

Serotonergic control of metabolic homeostasis

Wyler, S. C., Lord, C. C., Lee, S., Elmquist, J. K. & Liu, C., Sep 20 2017, In : Frontiers in Cellular Neuroscience. 11, 277.

Research output: Contribution to journalShort survey

Serotonin
Homeostasis
Metabolic Diseases
Thermogenesis
Lipid Metabolism
12 Citations (Scopus)

Short-term versus long-term effects of adipocyte toll-like receptor 4 activation on insulin resistance in male mice

Tao, C., Holland, W. L., Wang, Q. A., Shao, M., Jia, L., Sun, K., Lin, X., Kuo, Y. C., Johnson, J. A., Gordillo, R., Elmquist, J. K. & Scherer, P. E., May 1 2017, In : Endocrinology. 158, 5, p. 1260-1270 11 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Adipocytes
Insulin Resistance
Adipose Tissue
High Fat Diet
33 Citations (Scopus)

The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C

Lord, C. C., Wyler, S. C., Wan, R., Castorena, C. M., Ahmed, N., Mathew, D., Lee, S., Liu, C. & Elmquist, J. K., Sep 1 2017, In : Journal of Clinical Investigation. 127, 9, p. 3402-3406 5 p.

Research output: Contribution to journalArticle

olanzapine
Receptor, Serotonin, 5-HT2C
Antipsychotic Agents
Weight Gain
Hyperphagia
4 Citations (Scopus)

The hypothalamic regulation of metabolic adaptations to exercise

Fujikawa, T., Castorena, C. M., Lee, S. & Elmquist, J. K., Oct 1 2017, In : Journal of Neuroendocrinology. 29, 10, e12533.

Research output: Contribution to journalReview article

Sedentary Lifestyle
Food
Hypothalamus
Life Style
Chronic Disease
2016
28 Citations (Scopus)

Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals

Zhu, Y., Gao, Y., Tao, C., Shao, M., Zhao, S., Huang, W., Yao, T., Johnson, J. A., Liu, T., Cypess, A. M., Gupta, O., Holland, W. L., Gupta, R. K., Spray, D. C., Tanowitz, H. B., Cao, L., Lynes, M. D., Tseng, Y. H., Elmquist, J. K., Williams, K. W. & 2 others, Lin, H. V. & Scherer, P. E., Sep 13 2016, In : Cell Metabolism. 24, 3, p. 420-433 14 p.

Research output: Contribution to journalArticle

White Adipose Tissue
Connexin 43
Adipose Tissue
Pro-Opiomelanocortin
Glycyrrhetinic Acid
11 Citations (Scopus)

Leptin and insulin engage specific PI3K subunits in hypothalamic SF1 neurons

Sohn, J. W., Oh, Y., Kim, K. W., Lee, S., Williams, K. W. & Elmquist, J. K., Aug 1 2016, In : Molecular Metabolism. 5, 8, p. 669-679 11 p.

Research output: Contribution to journalArticle

Steroidogenic Factor 1
Leptin
Phosphatidylinositol 3-Kinases
Ventromedial Hypothalamic Nucleus
Insulin

Mechanisms of homeostatically regulated behaviors

Elmquist, J. K., Zigman, J. M. & Saper, C. B., Jan 1 2016, Neuroscience in the 21st Century: From Basic to Clinical, Second Edition. Springer New York, p. 2087-2116 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

hypothalamic regulation
Appetite Regulation
Body Temperature
Thyroid Hormones
Energy Metabolism
4 Citations (Scopus)

Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination

Lee, J., Yang, D. J., Lee, S., Hammer, G. D., Kim, K. W. & Elmquist, J. K., Jan 11 2016, In : Scientific Reports. 6, 19143.

Research output: Contribution to journalArticle

Steroidogenic Factor 1
Sumoylation
Ubiquitination
Starvation
Homeostasis
13 Citations (Scopus)

SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise

Fujikawa, T., Castorena, C. M., Pearson, M., Kusminski, C., Ahmed, N., Battiprolu, P. K., Kim, K. W., Lee, S., Hill, J. A., Scherer, P. E., Holland, W. L. & Elmquist, J. K., Nov 22 2016, In : eLife. 5, NOVEMBER2016, e18206.

Research output: Contribution to journalArticle

Steroidogenic Factor 1
Ventromedial Hypothalamic Nucleus
Metabolism
Hypothalamus
Neurology
2015
151 Citations (Scopus)

A neural basis for melanocortin-4 receptor-regulated appetite

Garfield, A. S., Li, C., Madara, J. C., Shah, B. P., Webber, E., Steger, J. S., Campbell, J. N., Gavrilova, O., Lee, C. E., Olson, D. P., Elmquist, J. K., Tannous, B. A., Krashes, M. J. & Lowell, B. B., Jun 28 2015, In : Nature Neuroscience. 18, 6, p. 863-871 9 p.

Research output: Contribution to journalArticle

Receptor, Melanocortin, Type 4
Appetite
Paraventricular Hypothalamic Nucleus
Hypothalamus
Neurons

Development of neuroendocrine systems governing energy homeostasis

Elmquist, J. K., Oct 1 2015, In : Frontiers in Neuroendocrinology. 39, p. 1-2 2 p.

Research output: Contribution to journalArticle

Neurosecretory Systems
Energy Metabolism
Homeostasis
175 Citations (Scopus)

Hypothalamic POMC neurons promote cannabinoid-induced feeding

Koch, M., Varela, L., Kim, J. G., Kim, J. D., Hernández-Nuño, F., Simonds, S. E., Castorena, C. M., Vianna, C. R., Elmquist, J. K., Morozov, Y. M., Rakic, P., Bechmann, I., Cowley, M. A., Szigeti-Buck, K., Dietrich, M. O., Gao, X. B., Diano, S. & Horvath, T. L., Mar 5 2015, In : Nature. 519, 7541, p. 45-50 6 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Cannabinoids
Neurons
Designer Drugs
Endorphins
47 Citations (Scopus)

Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions

Arble, D. M., Bass, J., Behn, C. D., Butler, M. P., Challet, E., Czeisler, C., Depner, C. M., Elmquist, J., Franken, P., Grandner, M. A., Hanlon, E. C., Keene, A. C., Joyner, M. J., Karatsoreos, I., Kern, P. A., Klein, S., Morris, C. J., Pack, A. I., Panda, S., Ptacek, L. J. & 8 others, Punjabi, N. M., Sassone-Corsi, P., Scheer, F. A., Saxena, R., Seaquest, E. R., Thimgan, M. S., Van Cauter, E. & Wright, K. P., Dec 1 2015, In : Sleep. 38, 12, p. 1849-1860 12 p.

Research output: Contribution to journalArticle

Sleep
Education
Research Personnel
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Research
11 Citations (Scopus)

Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure

Mansuy-Aubert, V., Gautron, L., Lee, S., Bookout, A. L., Kusminski, C. M., Sun, K., Zhang, Y., Scherer, P. E., Mangelsdorf, D. J. & Elmquist, J. K., Jun 15 2015, In : eLife. 4, JUNE, e06667.

Research output: Contribution to journalArticle

Sensory Receptor Cells
Liver
Energy Metabolism
Neurons
Nodose Ganglion
6 Citations (Scopus)

Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice

Yan, C., Yang, Y., Saito, K., Xu, P., Wang, C., Hinton, A. O., Yan, X., Wu, Q., Tong, Q., Elmquist, J. K., Fukuda, M. & Xu, Y., Jul 1 2015, In : British Journal of Pharmacology. 172, 14, p. 3510-3521 12 p.

Research output: Contribution to journalArticle

Obese Mice
Leptin
Diet
Receptor, Serotonin, 5-HT2C
Obesity
100 Citations (Scopus)

Neural control of energy balance: Translating circuits to therapies

Gautron, L., Elmquist, J. K. & Williams, K. W., Mar 26 2015, In : Cell. 161, 1, p. 133-145 13 p., 8054.

Research output: Contribution to journalArticle

Medical problems
Energy balance
Obesity
Glucose
Networks (circuits)
2014
110 Citations (Scopus)

Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin

Wang, Q., Liu, C., Uchida, A., Chuang, J. C., Walker, A., Liu, T., Osborne-Lawrence, S., Mason, B. L., Mosher, C., Berglund, E. D., Elmquist, J. K. & Zigman, J. M., Feb 2014, In : Molecular Metabolism. 3, 1, p. 64-72 9 p.

Research output: Contribution to journalArticle

Ghrelin
Neurons
Caloric Restriction
Blood Glucose
Ghrelin Receptor
16 Citations (Scopus)

Circuits controlling energy balance and mood: Inherently intertwined or just complicated intersections?

Liu, C., Lee, S. & Elmquist, J. K., Jun 3 2014, In : Cell Metabolism. 19, 6, p. 902-909 8 p.

Research output: Contribution to journalArticle

Pleasure
Psychiatry
Weight Loss
Brain
Therapeutics
23 Citations (Scopus)

Dnmt3a in sim1 neurons is necessary for normal energy homeostasis

Kohno, D., Lee, S., Harper, M. J., Kim, K. W., Sone, X., Sasaki, T., Kitamura, T., Fan, G. & Elmquist, J. K., Nov 12 2014, In : Journal of Neuroscience. 34, 46, p. 15288-15296 9 p.

Research output: Contribution to journalArticle

Paraventricular Hypothalamic Nucleus
Hypothalamus
Homeostasis
Neurons
Tyrosine 3-Monooxygenase
22 Citations (Scopus)

Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice

Asterholm, I. W., Rutkowski, J. M., Fujikawa, T., Cho, Y. R., Fukuda, M., Tao, C., Wang, Z., Gupta, R. K., Elmquist, J. K. & Scherer, P. E., 2014, In : Diabetologia. 57, 6, p. 1209-1218 10 p.

Research output: Contribution to journalArticle

Resistin
Leptin
Insulin Resistance
LDL Receptors
Triglycerides

Foreword

Gautron, L. & Elmquist, J. K., 2014, In : Frontiers of Hormone Research. 42

Research output: Contribution to journalArticle

Foreword

Gautron, L. & Elmquist, J. K., Apr 10 2014, In : Unknown Journal. 42, p. vii-viii

Research output: Contribution to journalArticle

112 Citations (Scopus)

Hepatocyte toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance

Jia, L., Vianna, C. R., Fukuda, M., Berglund, E. D., Liu, C., Tao, C., Sun, K., Liu, T., Harper, M. J., Lee, C. E., Lee, S., Scherer, P. E. & Elmquist, J. K., May 12 2014, In : Nature Communications. 5, 3878.

Research output: Contribution to journalArticle

obesity
insulin
Toll-Like Receptor 4
Insulin Resistance
Hepatocytes
22 Citations (Scopus)

Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia.

Heymsfield, S. B., Avena, N. M., Baier, L., Brantley, P., Bray, G. A., Burnett, L. C., Butler, M. G., Driscoll, D. J., Egli, D., Elmquist, J., Forster, J. L., Goldstone, A. P., Gourash, L. M., Greenway, F. L., Han, J. C., Kane, J. G., Leibel, R. L., Loos, R. J. F., Scheimann, A. O., Roth, C. L. & 9 others, Seeley, R. J., Sheffield, V., Tauber, M., Vaisse, C., Wang, L., Waterland, R. A., Wevrick, R., Yanovski, J. A. & Zinn, A. R., 2014, In : Obesity (Silver Spring, Md.). 22 Suppl 1

Research output: Contribution to journalArticle

Hyperphagia
Obesity
Research
Prader-Willi Syndrome
Caregivers
152 Citations (Scopus)

Leptin mediates the increase in blood pressure associated with obesity

Simonds, S. E., Pryor, J. T., Ravussin, E., Greenway, F. L., Dileone, R., Allen, A. M., Bassi, J., Elmquist, J. K., Keogh, J. M., Henning, E., Myers, M. G., Licinio, J., Brown, R. D., Enriori, P. J., O'Rahilly, S., Sternson, S. M., Grove, K. L., Spanswick, D. C., Farooqi, I. S. & Cowley, M. A., Dec 4 2014, In : Cell. 159, 6, p. 1404-1416 13 p.

Research output: Contribution to journalArticle

Blood pressure
Leptin
Obesity
Leptin Receptors
Blood Pressure
80 Citations (Scopus)

MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus

Shah, B. P., Vong, L., Olson, D. P., Koda, S., Krashes, M. J., Ye, C., Yang, Z., Fuller, P. M., Elmquist, J. K. & Lowell, B. B., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 36, p. 13193-13198 6 p.

Research output: Contribution to journalArticle

Receptor, Melanocortin, Type 4
Hypothalamus
Neurons
Obesity
Parabrachial Nucleus
68 Citations (Scopus)

Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia

Berglund, E. D., Liu, T., Kong, X., Sohn, J. W., Vong, L., Deng, Z., Lee, C. E., Lee, S., Williams, K. W., Olson, D. P., Scherer, P. E., Lowell, B. B. & Elmquist, J. K., 2014, In : Nature Neuroscience. 17, 7, p. 911-913 3 p.

Research output: Contribution to journalArticle

Receptor, Melanocortin, Type 4
Cholinergic Neurons
Thermogenesis
Homeostasis
Neurons
33 Citations (Scopus)

PPARγ in vagal neurons regulates high-fat diet induced thermogenesis

Liu, C., Bookout, A. L., Lee, S., Sun, K., Jia, L., Lee, C., Udit, S., Deng, Y., Scherer, P. E., Mangelsdorf, D. J., Gautron, L. & Elmquist, J. K., Apr 1 2014, In : Cell Metabolism. 19, 4, p. 722-730 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Thermogenesis
High Fat Diet
Nodose Ganglion
Neurons
3 Citations (Scopus)
Receptor, Serotonin, 5-HT2C
Pro-Opiomelanocortin
Homeostasis
Neurons
Glucose
18 Citations (Scopus)

Shp2 signaling in POMC neurons is important for leptin’s actions on blood pressure, Energy balance, And glucose regulation

Do Carmo, J. M., Da Silva, A. A., Ebaady, S. E., Sessums, P. O., Abraham, R. S., Elmquist, J. K., Lowell, B. B. & Hall, J. E., Dec 15 2014, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 307, 12, p. R1438-R1447

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Leptin
Blood Pressure
Neurons
Glucose
119 Citations (Scopus)

Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis

Williams, K. W., Liu, T., Kong, X., Fukuda, M., Deng, Y., Berglund, E. D., Deng, Z., Gao, Y., Liu, T., Sohn, J. W., Jia, L., Fujikawa, T., Kohno, D., Scott, M. M., Lee, S., Lee, C. E., Sun, K., Chang, Y., Scherer, P. E. & Elmquist, J. K., Sep 2 2014, In : Cell Metabolism. 20, 3, p. 471-482 12 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Insulin Resistance
Homeostasis
Leptin
Neurons
2013
7 Citations (Scopus)

Discrete melanocortin-sensitive neuroanatomical pathway linking the ventral premmamillary nucleus to the paraventricular hypothalamus

Gautron, L., Cravo, R. M., Elmquist, J. K. & Elias, C. F., Jun 14 2013, In : Neuroscience. 240, p. 70-82 13 p.

Research output: Contribution to journalArticle

Melanocortins
Receptor, Melanocortin, Type 4
Paraventricular Hypothalamic Nucleus
Hypothalamus
Neurons
227 Citations (Scopus)

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

Bookout, A. L., De Groot, M. H. M., Owen, B. M., Lee, S., Gautron, L., Lawrence, H. L., Ding, X., Elmquist, J. K., Takahashi, J. S., Mangelsdorf, D. J. & Kliewer, S. A., Sep 2013, In : Nature Medicine. 19, 9, p. 1147-1152 6 p.

Research output: Contribution to journalArticle

Neurology
Metabolism
Nervous System
Starvation
Receptor, Fibroblast Growth Factor, Type 2
67 Citations (Scopus)

Leptin Engages a Hypothalamic Neurocircuitry to Permit Survival in the Absence of Insulin

Fujikawa, T., Berglund, E. D., Patel, V. R., Ramadori, G., Vianna, C. R., Vong, L., Thorel, F., Chera, S., Herrera, P. L., Lowell, B. B., Elmquist, J. K., Baldi, P. & Coppari, R., Sep 3 2013, In : Cell Metabolism. 18, 3, p. 431-444 14 p.

Research output: Contribution to journalArticle

Leptin
Insulin
Leptin Receptors
Aminobutyrates
Deficiency Diseases
1 Citation (Scopus)

Mechanisms of homeostatically regulated behaviors

Elmquist, J. K., Zigman, J. M. & Saper, C. B., Nov 1 2013, Neuroscience in the 21st Century: From Basic to Clinical. Springer New York, p. 1753-1782 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Appetite Regulation
Body Temperature
Thyroid Hormones
Energy Metabolism
Hypothalamus
118 Citations (Scopus)

Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons

Sohn, J. W., Harris, L. E., Berglund, E. D., Liu, T., Vong, L., Lowell, B. B., Balthasar, N., Williams, K. W. & Elmquist, J. K., Jan 31 2013, In : Cell. 152, 3, p. 612-619 8 p.

Research output: Contribution to journalArticle

Receptor, Melanocortin, Type 4
Neurons
Cholinergic Neurons
Cholinergic Agents
Obesity
8 Citations (Scopus)

Mrap2: An accessory protein linked to obesity

Liu, T., Elmquist, J. K. & Williams, K. W., Sep 3 2013, In : Cell Metabolism. 18, 3, p. 309-311 3 p.

Research output: Contribution to journalArticle

Melanocortin Receptors
Obesity
Proteins
Zebrafish
Rodentia