• 3224 Citations
  • 30 h-Index
19992020

Research output per year

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Research Output

  • 3224 Citations
  • 30 h-Index
  • 61 Article
  • 3 Review article
  • 1 Letter
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Article

[3 + 2]-Cycloadditions of Azomethine Imines and Ynolates

Winterton, S. E. & Ready, J. M., Jun 3 2016, In : Organic Letters. 18, 11, p. 2608-2611 4 p.

Research output: Contribution to journalArticle

23 Scopus citations

A Concise Total Synthesis of Dictyodendrins F, H, and i Using Aryl Ynol Ethers as Key Building Blocks

Zhang, W. & Ready, J. M., Aug 24 2016, In : Journal of the American Chemical Society. 138, 33, p. 10684-10692 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication

Luthra, P., Liang, J., Pietzsch, C. A., Khadka, S., Edwards, M. R., Wei, S., De, S., Posner, B., Bukreyev, A., Ready, J. M. & Basler, C. F., Feb 1 2018, In : Antiviral Research. 150, p. 193-201 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Allenes in asymmetric catalysis: Asymmetric ring opening of meso-epoxides catalyzed by allene-containing phosphine oxides

Pu, X., Qi, X. & Ready, J. M., Aug 5 2009, In : Journal of the American Chemical Society. 131, 30, p. 10364-10365 2 p.

Research output: Contribution to journalArticle

80 Scopus citations

A mild and efficient synthesis of oxindoles: Progress towards the synthesis of welwitindolinone A isonitrile

Ready, J. M., Reisman, S. E., Hirata, M., Weiss, M. M., Tamaki, K., Ovaska, T. V. & Wood, J. L., Feb 27 2004, In : Angewandte Chemie - International Edition. 43, 10, p. 1270-1272 3 p.

Research output: Contribution to journalArticle

71 Scopus citations

A practical oligomeric [(salen)Co] catalyst for asymmetric epoxide ring-opening reactions

Ready, J. M. & Jacobsen, E. N., Apr 15 2002, In : Angewandte Chemie - International Edition. 41, 8, p. 1374-1377 4 p.

Research output: Contribution to journalArticle

221 Scopus citations

A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support

Desai, A., Zhang, Y., Park, Y., Dawson, D. M., Larusch, G. A., Kasturi, L., Wald, D., Ready, J. M., Gerson, S. L. & Markowitz, S. D., Jun 3 2018, In : Haematologica. 103, 6, p. 1054-1064 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Asymmetric synthesis of tertiary benzylic alcohols

Antczak, M. I., Cai, F. & Ready, J. M., Jan 21 2011, In : Organic Letters. 13, 2, p. 184-187 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Catalytic cross-coupling of alkylzinc halides with α-chloroketones

Malosh, C. F. & Ready, J. M., Aug 25 2004, In : Journal of the American Chemical Society. 126, 33, p. 10240-10241 2 p.

Research output: Contribution to journalArticle

56 Scopus citations

Chiral allene-containing phosphines in asymmetric catalysis

Cai, F., Pu, X., Qi, X., Lynch, V., Radha, A. & Ready, J. M., Nov 16 2011, In : Journal of the American Chemical Society. 133, 45, p. 18066-18069 4 p.

Research output: Contribution to journalArticle

80 Scopus citations

Copper-promoted cycloaddition of diazocarbonyl compounds and acetylides

Qi, X. & Ready, J. M., Jun 29 2007, In : Angewandte Chemie - International Edition. 46, 18, p. 3242-3244 3 p.

Research output: Contribution to journalArticle

84 Scopus citations

Cyclocondensation of amino-propargyl silanes

Wang, Y. & Ready, J. M., May 4 2012, In : Organic Letters. 14, 9, p. 2308-2311 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Deconvolution of complex NMR spectra in small molecules by multi frequency homonuclear decoupling (MDEC)

Espindola, A. P. D. M., Crouch, R., DeBergh, J. R., Ready, J. M. & MacMillan, J. B., Nov 27 2009, In : Journal of the American Chemical Society. 131, 44, p. 15994-15995 2 p.

Research output: Contribution to journalArticle

28 Scopus citations

Dehydrogenative coupling to enable the enantioselective total synthesis of (-)-simaomicin α

Wang, Y., Wang, C., Butler, J. R. & Ready, J. M., Oct 4 2013, In : Angewandte Chemie - International Edition. 52, 41, p. 10796-10799 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Development of a scalable synthesis of P7C3-A20, a potent neuroprotective agent

Naidoo, J., Bemben, C. J., Allwein, S. R., Liang, J., Pieper, A. A. & Ready, J. M., Aug 14 2013, In : Tetrahedron Letters. 54, 33, p. 4429-4431 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Development of proneurogenic, neuroprotective small molecules

MacMillan, K. S., Naidoo, J., Liang, J., Melito, L., Williams, N. S., Morlock, L., Huntington, P. J., Estill, S. J., Longgood, J., Becker, G. L., McKnight, S. L., Pieper, A. A., De Brabander, J. K. & Ready, J. M., Feb 9 2011, In : Journal of the American Chemical Society. 133, 5, p. 1428-1437 10 p.

Research output: Contribution to journalArticle

115 Scopus citations

Direct and stereospecific synthesis of allenes via reduction of propargylic alcohols with Cp2Zr(H)Cl

Pu, X. & Ready, J. M., Aug 20 2008, In : Journal of the American Chemical Society. 130, 33, p. 10874-10875 2 p.

Research output: Contribution to journalArticle

76 Scopus citations

Directed hydrozirconation of homopropargylic alcohols

Liu, X. & Ready, J. M., Jul 14 2008, In : Tetrahedron. 64, 29, p. 6955-6960 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Directed hydrozirconation of propargylic alcohols

Zhang, D. & Ready, J. M., Oct 10 2007, In : Journal of the American Chemical Society. 129, 40, p. 12088-12089 2 p.

Research output: Contribution to journalArticle

26 Scopus citations

Discovery of a neuroprotective chemical, (S)- N -(3-(3,6-Dibromo-9 H -carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties

Naidoo, J., De Jesus-Cortes, H., Huntington, P., Estill, S., Morlock, L. K., Starwalt, R., Mangano, T. J., Williams, N. S., Pieper, A. A. & Ready, J. M., May 8 2014, In : Journal of Medicinal Chemistry. 57, 9, p. 3746-3754 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Discovery of a Proneurogenic, Neuroprotective Chemical

Pieper, A. A., Xie, S., Capota, E., Estill, S. J., Zhong, J., Long, J. M., Becker, G. L., Huntington, P., Goldman, S. E., Shen, C. H., Capota, M., Britt, J. K., Kotti, T., Ure, K., Brat, D. J., Williams, N. S., MacMillan, K. S., Naidoo, J., Melito, L., Hsieh, J. & 3 others, De Brabander, J. K., Ready, J. M. & McKnight, S. L., Jul 1 2010, In : Cell. 142, 1, p. 39-51 13 p.

Research output: Contribution to journalArticle

225 Scopus citations

Discovery of Cytochrome P450 4F11 Activated Inhibitors of Stearoyl Coenzyme A Desaturase

Winterton, S. E., Capota, E., Wang, X., Chen, H., Mallipeddi, P. L., Williams, N. S., Posner, B. A., Nijhawan, D. & Ready, J. M., Jun 28 2018, In : Journal of Medicinal Chemistry. 61, 12, p. 5199-5221 23 p.

Research output: Contribution to journalArticle

1 Scopus citations

Discovery of small-molecule inhibitors of tyrosinase

Germanas, J. P., Wang, S., Miner, A., Hao, W. & Ready, J. M., Dec 15 2007, In : Bioorganic and Medicinal Chemistry Letters. 17, 24, p. 6871-6875 5 p.

Research output: Contribution to journalArticle

46 Scopus citations

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase

Theodoropoulos, P. C., Gonzales, S. S., Winterton, S. E., Rodriguez-Navas, C., McKnight, J. S., Morlock, L. K., Hanson, J. M., Cross, B., Owen, A. E., Duan, Y., Moreno, J. R., Lemoff, A., Mirzaei, H., Posner, B. A., Williams, N. S., Ready, J. M. & Nijhawan, D., Apr 1 2016, In : Nature Chemical Biology. 12, 4, p. 218-225 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Enantioselective total synthesis of ( - )-kibdelone C

Butler, J. R., Wang, C., Bian, J. & Ready, J. M., Jul 6 2011, In : Journal of the American Chemical Society. 133, 26, p. 9956-9959 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

Enantioselective total synthesis of (+)- and (-)-nigellamine A2

Bian, J., Van Wingerden, M. & Ready, J. M., Jun 14 2006, In : Journal of the American Chemical Society. 128, 23, p. 7428-7429 2 p.

Research output: Contribution to journalArticle

59 Scopus citations

Evolution of a synthetic strategy: Total synthesis of (±)- welwitindolinone A isonitrile

Reisman, S. E., Ready, J. M., Weiss, M. M., Hasuoka, A., Hirata, M., Tamaki, K., Ovaska, T. V., Smith, C. J. & Wood, J. L., Feb 13 2008, In : Journal of the American Chemical Society. 130, 6, p. 2087-2100 14 p.

Research output: Contribution to journalArticle

125 Scopus citations

Identification of DNMT1 selective antagonists using a novel scintillation proximity assay

Kilgore, J. A., Du, X., Melito, L., Wei, S., Wang, C., Chin, H. G., Posner, B., Pradhan, S., Ready, J. M. & Williams, N. S., Jul 5 2013, In : Journal of Biological Chemistry. 288, 27, p. 19673-19684 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

Luthra, P., Naidoo, J., Pietzsch, C. A., De, S., Khadka, S., Anantpadma, M., Williams, C. G., Edwards, M. R., Davey, R. A., Bukreyev, A., Ready, J. M. & Basler, C. F., Oct 1 2018, In : Antiviral Research. 158, p. 288-302 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

Zhang, Y., Desai, A., Yang, S. Y., Bae, K. B., Antczak, M. I., Fink, S. P., Tiwari, S., Willis, J. E., Williams, N. S., Dawson, D. M., Wald, D., Chen, W. D., Wang, Z., Kasturi, L., Larusch, G. A., He, L., Cominelli, F., Di Martino, L., Djuric, Z., Milne, G. L. & 12 others, Chance, M., Sanabria, J., Dealwis, C., Mikkola, D., Naidoo, J., Wei, S., Tai, H. H., Gerson, S. L., Ready, J. M., Posner, B., Willson, J. K. V. & Markowitz, S. D., Jun 12 2015, In : Science. 348, 6240, 2340.

Research output: Contribution to journalArticle

98 Scopus citations

Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair

Antczak, M. I., Zhang, Y., Wang, C., Doran, J., Naidoo, J., Voruganti, S., Williams, N. S., Markowitz, S. D. & Ready, J. M., May 11 2017, In : Journal of Medicinal Chemistry. 60, 9, p. 3979-4001 23 p.

Research output: Contribution to journalArticle

10 Scopus citations

In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity

Brown, C. S., Lee, M. S., Leung, D. W., Wang, T., Xu, W., Luthra, P., Anantpadma, M., Shabman, R. S., Melito, L. M., Macmillan, K. S., Borek, D. M., Otwinowski, Z., Ramanan, P., Stubbs, A. J., Peterson, D. S., Binning, J. M., Tonelli, M., Olson, M. A., Davey, R. A., Ready, J. M. & 2 others, Basler, C. F. & Amarasinghe, G. K., May 15 2014, In : Journal of Molecular Biology. 426, 10, p. 2045-2058 14 p.

Research output: Contribution to journalArticle

42 Scopus citations

Iron-catalyzed carbometalation of propargylic and homopropargylic alcohols

Zhang, D. & Ready, J. M., Nov 29 2006, In : Journal of the American Chemical Society. 128, 47, p. 15050-15051 2 p.

Research output: Contribution to journalArticle

91 Scopus citations

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

Tesla, R., Wolf, H., Xu, P., Drawbridge, J., Estill, S., Huntington, P., McDaniel, L., Knobbe, W., Burket, A., Tran, S., Starwalt, R., Morlock, L., Naidoo, J., Williams, N. S., Ready, J. M., McKnight, S. L. & Pieper, A. A., Oct 16 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 42, p. 17016-17021 6 p.

Research output: Contribution to journalArticle

83 Scopus citations

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

De Jesús-Cort́es, H., Xu, P., Drawbridge, J., Estill, S. J., Huntington, P., Tran, S., Britt, J., Tesla, R., Morlock, L., Naidoo, J., Melito, L. M., Wang, G., Williams, N. S., Ready, J. M., McKnight, S. L. & Pieper, A. A., Oct 16 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 42, p. 17010-17015 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

On the rapid oxidation of allene-containing phosphines

Cai, F., Thangada, N. D., Pan, E. & Ready, J. M., Oct 14 2013, In : Organometallics. 32, 19, p. 5619-5622 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Optically active allenes from an allylic substitution/isomerization sequence

Zhang, W. & Ready, J. M., Dec 1 2013, In : ChemCatChem. 5, 12, p. 3497-3498 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury

Yin, T. C., Britt, J. K., De Jesús-Cortés, H., Lu, Y., Genova, R. M., Khan, M. Z., Voorhees, J. R., Shao, J., Katzman, A. C., Huntington, P. J., Wassink, C., McDaniel, L., Newell, E. A., Dutca, L. M., Naidoo, J., Cui, H., Bassuk, A. G., Harper, M. M., McKnight, S. L., Ready, J. M. & 1 others, Pieper, A. A., Sep 25 2014, In : Cell Reports. 8, 6, p. 1731-1740 10 p.

Research output: Contribution to journalArticle

66 Scopus citations

P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage.

Wang, G., Han, T., Nijhawan, D., Theodoropoulos, P., Naidoo, J., Yadavalli, S., Mirzaei, H., Pieper, A. A., Ready, J. M. & McKnight, S. L., Sep 11 2014, In : Cell. 158, 6, p. 1324-1334 11 p.

Research output: Contribution to journalArticle

110 Scopus citations

Palladium Catalyzed Asymmetric Three-Component Coupling of Boronic Esters, Indoles, and Allylic Acetates

Panda, S. & Ready, J. M., May 3 2017, In : Journal of the American Chemical Society. 139, 17, p. 6038-6041 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury

Kemp, S. W. P., Szynkaruk, M., Stanoulis, K. N., Wood, M. D., Liu, E. H., Willand, M. P., Morlock, L., Naidoo, J., Williams, N. S., Ready, J. M., Mangano, T. J., Beggs, S., Salter, M. W., Gordon, T., Pieper, A. A. & Borschel, G. H., Jan 2 2015, In : Neuroscience. 284, p. 202-216 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Preparation of substituted enol derivatives from terminal alkynes and their synthetic utility

DeBergh, J. R., Spivey, K. M. & Ready, J. M., Jun 25 2008, In : Journal of the American Chemical Society. 130, 25, p. 7828-7829 2 p.

Research output: Contribution to journalArticle

40 Scopus citations

Prostaglandin dehydrogenase is a target for successful induction of cervical ripening

Kishore, A. H., Liang, H., Kanchwala, M., Xing, C., Ganesh, T., Akgul, Y., Posner, B., Ready, J. M., Markowitz, S. D. & Word, R. A., Aug 1 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 31, p. E6427-E6436

Research output: Contribution to journalArticle

11 Scopus citations

Rhodium-Catalyzed Enantioselective Radical Addition of CX4 Reagents to Olefins

Chen, B., Fang, C., Liu, P. & Ready, J. M., Jul 17 2017, In : Angewandte Chemie - International Edition. 56, 30, p. 8780-8784 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Science at the interface of chemistry and biology at the University of Texas Southwestern Medical Center

Ready, J. M. & Lynch, K. W., Aug 1 2007, In : ACS Chemical Biology. 2, 8, p. 512-514 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Selective Synthesis of (+)-Dysoline

Coffin, A. & Ready, J. M., Feb 1 2019, In : Organic Letters. 21, 3, p. 648-651 4 p.

Research output: Contribution to journalArticle

Structure elucidation of nigricanoside A through enantioselective total synthesis

Chen, J., Koswatta, P., DeBergh, J. R., Fu, P., Pan, E., MacMillan, J. B. & Ready, J. M., May 1 2015, In : Chemical Science. 6, 5, p. 2932-2937 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives

Rujirawanich, J., Kim, S., Ma, A. J., Butler, J. R., Wang, Y., Wang, C., Rosen, M., Posner, B., Nijhawanc, D. & Ready, J. M., Aug 24 2016, In : Journal of the American Chemical Society. 138, 33, p. 10561-10570 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Synthesis and utility of dihydropyridine boronic esters

Panda, S., Coffin, A., Nguyen, Q. N., Tantillo, D. J. & Ready, J. M., Feb 5 2016, In : Angewandte Chemie - International Edition. 55, 6, p. 2205-2209 5 p.

Research output: Contribution to journalArticle

19 Scopus citations