• 846 Citations
  • 13 h-Index
19992007
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Fingerprint Dive into the research topics where Joseph McLaughlin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
PAR-1 Receptor Medicine & Life Sciences
GTP-Binding Proteins Medicine & Life Sciences
Chaperonin Containing TCP-1 Medicine & Life Sciences
Thrombin Medicine & Life Sciences
Proteins Medicine & Life Sciences
Chaperonins Medicine & Life Sciences
Chemical activation Chemical Compounds
Phosphorylation Medicine & Life Sciences

Research Output 1999 2007

  • 846 Citations
  • 13 h-Index
  • 13 Article
57 Citations (Scopus)

PAR1, but not PAR4, activates human platelets through a G i/o/phosphoinositide-3 kinase signaling axis

Voss, B., McLaughlin, J. N., Holinstat, M., Zent, R. & Hamm, H. E., May 1 2007, In : Molecular Pharmacology. 71, 5, p. 1399-1406 8 p.

Research output: Contribution to journalArticle

PAR-1 Receptor
1-Phosphatidylinositol 4-Kinase
Blood Platelets
clopidogrel
Platelet Activation
127 Citations (Scopus)

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization

McLaughlin, J. N., Patterson, M. M. & Malik, A. B., Mar 27 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 13, p. 5662-5667 6 p.

Research output: Contribution to journalArticle

Open Access
PAR-1 Receptor
Dimerization
Thrombin
Permeability
protease-activated receptor 3
80 Citations (Scopus)

PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation

Holinstat, M., Voss, B., Bilodeau, M. L., McLaughlin, J. N., Cleator, J. & Hamm, H. E., Sep 8 2006, In : Journal of Biological Chemistry. 281, 36, p. 26665-26674 10 p.

Research output: Contribution to journalArticle

Open Access
Platelets
Platelet Aggregation
Thrombin
Blood Platelets
Agglomeration
151 Citations (Scopus)

Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1

McLaughlin, J. N., Shen, L., Holinstat, M., Brooks, J. D., DiBenedetto, E. & Hamm, H. E., Jul 1 2005, In : Journal of Biological Chemistry. 280, 26, p. 25048-25059 12 p.

Research output: Contribution to journalArticle

Open Access
PAR-1 Receptor
GTP-Binding Proteins
Thrombin
Chemical activation
Calcium
69 Citations (Scopus)

Phosducin-like protein acts as a molecular chaperone for G protein βγ dimer assembly

Lukov, G. L., Hu, T., McLaughlin, J. N., Hamm, H. E. & Willardson, B. M., Jun 1 2005, In : EMBO Journal. 24, 11, p. 1965-1975 11 p.

Research output: Contribution to journalArticle

Molecular Chaperones
GTP-Binding Proteins
Dimers
Proteins
Phosphorylation