• 21039 Citations
  • 48 h-Index
19982019

Research output per year

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Research Output

2019

Author Correction: miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2 (Nature, (2014), 512, 7515, (431-435), 10.1038/nature13375)

Krzeszinski, J. Y., Wei, W., Huynh, H. D., Jin, Z., Wang, X., Chang, T-C., Xie, X-J., He, L., Mangala, L. S., Lopez-Berestein, G., Sood, A. K., Mendell, J. T. & Wan, Y., Jan 1 2019, In : Nature.

Research output: Contribution to journalComment/debate

Open Access

MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary

Du, Q., Hoover, A. R., Dozmorov, I., Raj, P., Khan, S., Molina, E., Chang, T-C., De La Morena, M. T., Cleaver, O., Mendell, J. T. & Van Oers, N., May 20 2019, In : Developmental Cell. 49, 4, p. 618-631.e5

Research output: Contribution to journalArticle

4 Scopus citations

MiR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19

Acharya, A., Berry, D. C., Zhang, H., Jiang, Y., Jones, B. T., Hammer, R. E., Graff, J. M. & Mendell, J. T., Oct 1 2019, In : Genes and Development. 33, 19-20, p. 1367-1380 14 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD

Elguindy, M. M., Kopp, F., Goodarzi, M., Rehfeld, F., Thomas, A., Chang, T. C. & Mendell, J. T., Jul 1 2019, In : eLife. 8, e48625.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Kopp, F., Elguindy, M. M., Yalvac, M. E., Zhang, H., Chen, B., Gillett, F. A., Lee, S., Sivakumar, S., Yu, H., Xie, Y., Mishra, P., Sahenk, Z. & Mendell, J. T., Feb 8 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2018

Functional Classification and Experimental Dissection of Long Noncoding RNAs

Kopp, F. & Mendell, J. T., Jan 25 2018, In : Cell. 172, 3, p. 393-407 15 p.

Research output: Contribution to journalReview article

382 Scopus citations

High-throughput characterization of primary microRNA transcripts

Chang, T. C. & Mendell, J. T., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 1-9 9 p. (Methods in Molecular Biology; vol. 1823).

Research output: Chapter in Book/Report/Conference proceedingChapter

Loss of Dis3l2 partially phenocopies perlman syndrome in mice and results in upregulation of Igf2 in nephron progenitor cells

Hunter, R. W., Liu, Y., Manjunath, H., Acharya, A., Jones, B. T., Zhang, H., Chen, B., Ramalingam, H., Hammer, R. E., Xie, Y., Richardson, J. A., Rakheja, D., Carroll, T. J. & Mendell, J. T., Jul 1 2018, In : Genes and Development. 32, 13-14, p. 903-908 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mutations in microRNA processing genes in wilms tumors derepress the IGF2 regulator PLAG1

Chen, K., Stroup, E. K., Budhipramono, A., Rakheja, D., Nichols-Vinueza, D., Xu, L., Stuart, S. H., Shukla, A. A., Fraire, C., Mendell, J. T. & Amatruda, J. F., Aug 1 2018, In : Genes and Development. 32, 15-16, p. 996-1007 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice

Quirin, K. A., Kwon, J. J., Alioufi, A., Factora, T., Temm, C. J., Jacobsen, M., Sandusky, G. E., Shontz, K., Chicoine, L. G., Clark, K. R., Mendell, J. T., Korc, M. & Kota, J., Mar 16 2018, In : Molecular Therapy - Methods and Clinical Development. 8, p. 8-20 13 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

An Argonaute phosphorylation cycle promotes microRNA-mediated silencing

Golden, R. J., Chen, B., Li, T., Braun, J., Manjunath, H., Chen, X., Wu, J., Schmid, V., Chang, T. C., Kopp, F., Ramirez-Martinez, A., Tagliabracci, V. S., Chen, Z. J., Xie, Y. & Mendell, J. T., Feb 9 2017, In : Nature. 542, 7640, p. 197-202 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Erratum: Publisher Correction: Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours

Rakheja, D., Chen, K. S., Liu, Y., Shukla, A. A., Schmid, V., Chang, T. C., Khokhar, S., Wickiser, J. E., Karandikar, N. J., Malter, J. S., Mendell, J. T. & Amatruda, J. F., Jan 1 2017, In : Nature communications. 8, 1 p.

Research output: Contribution to journalComment/debate

Open Access

MicroRNA-29 overexpression by adeno-associated virus suppresses fibrosis and restores muscle function in combination with micro-dystrophin

Heller, K. N., Mendell, J. T., Mendell, J. R. & Rodino-Klapac, L. R., May 4 2017, In : JCI insight. 2, 9

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2016

Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins

Lee, S., Kopp, F., Chang, T. C., Sataluri, A., Chen, B., Sivakumar, S., Yu, H., Xie, Y. & Mendell, J. T., Jan 14 2016, In : Cell. 164, 1-2, p. 69-80 12 p.

Research output: Contribution to journalArticle

234 Scopus citations

Targeting a long noncoding RNA in breast cancer

Mendell, J. T., Jun 9 2016, In : New England Journal of Medicine. 374, 23, p. 2287-2289 3 p.

Research output: Contribution to journalArticle

74 Scopus citations

Transcriptional regulation of miR-31 by oncogenic KRAS mediates metastatic phenotypes by repressing RASA1

Kent, O. A., Mendell, J. T. & Rottapel, R., Mar 1 2016, In : Molecular Cancer Research. 14, 3, p. 267-277 11 p.

Research output: Contribution to journalArticle

25 Scopus citations
2015

Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms

Chang, T. C., Pertea, M., Lee, S., Salzberg, S. L. & Mendell, J. T., Sep 1 2015, In : Genome Research. 25, 9, p. 1401-1409 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Identification of miR-145 targets through an integrated omics analysis

Huang, T. C., Renuse, S., Pinto, S., Kumar, P., Yang, Y., Chaerkady, R., Godsey, B., Mendell, J. T., Halushka, M. K., Civin, C. I., Marchionni, L. & Pandey, A., Jan 1 2015, In : Molecular BioSystems. 11, 1, p. 197-207 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Precise let-7 expression levels balance organ regeneration against tumor suppression

Wu, L., Nguyen, L. H., Zhou, K., De Yvanka Soysa, T., Li, L., Miller, J. B., Tian, J., Locker, J., Zhang, S., Shinoda, G., Seligson, M. T., Zeitels, L. R., Acharya, A., Wang, S. C., Mendell, J. T., He, X., Nishino, J., Morrison, S. J., Siegwart, D. J., Daley, G. Q. & 2 others, Shyh-Chang, N. & Zhu, H., Oct 7 2015, In : eLife. 4, OCTOBER2015, e09431.

Research output: Contribution to journalArticle

31 Scopus citations

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

Pertea, M., Pertea, G. M., Antonescu, C. M., Chang, T. C., Mendell, J. T. & Salzberg, S. L., Feb 2015, In : Nature biotechnology. 33, 3, p. 290-295 6 p.

Research output: Contribution to journalArticle

1083 Scopus citations

Systemic delivery of scAAV8-encoded MiR-29a ameliorates hepatic fibrosis in carbon tetrachloride-treated mice

Knabel, M. K., Ramachandran, K., Karhadkar, S., Hwang, H. W., Creamer, T. J., Chivukula, R. R., Sheikh, F., Clark, K. R., Torbenson, M., Montgomery, R. A., Cameron, A. M., Mendell, J. T. & Warren, D. S., Apr 29 2015, In : PLoS One. 10, 4, e0124411.

Research output: Contribution to journalArticle

24 Scopus citations
2014

An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration

Chivukula, R. R., Shi, G., Acharya, A., Mills, E. W., Zeitels, L. R., Anandam, J. L., Abdelnaby, A. A., Balch, G. C., Mansour, J. C., Yopp, A. C., Maitra, A. & Mendell, J. T., May 22 2014, In : Cell. 157, 5, p. 1104-1116 13 p.

Research output: Contribution to journalArticle

114 Scopus citations

MiR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2

Krzeszinski, J. Y., Wei, W., Huynh, H., Jin, Z., Wang, X., Chang, T. C., Xie, X. J., He, L., Mangala, L. S., Lopez-Berestein, G., Sood, A. K., Mendell, J. T. & Wan, Y., Aug 28 2014, In : Nature. 512, 7515, p. 431-435 5 p.

Research output: Contribution to journalArticle

208 Scopus citations

PIPE-CLIP: A comprehensive online tool for CLIP-seq data analysis

Chen, B., Yun, J., Kim, M. S., Mendell, J. T. & Xie, Y., Jan 1 2014, In : Genome biology. 15, 1, R18.

Research output: Contribution to journalArticle

59 Scopus citations

Seeing through the miRage of tissue complexity

Shi, G. & Mendell, J. T., Oct 16 2014, In : Cell Cycle. 13, 19, p. 2988-2989 2 p.

Research output: Contribution to journalEditorial

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours

Rakheja, D., Chen, K., Liu, Y., Shukla, A. A., Schmid, V., Chang, T-C., Khokhar, S., Wickiser, J. E., Karandikar, N. J., Malter, J. S., Mendell, J. T. & Amatruda, J. F., Sep 5 2014, In : Nature communications. 2, 4802.

Research output: Contribution to journalArticle

104 Scopus citations

Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis

Zeitels, L. R., Acharya, A., Shi, G., Chivukula, D., Chivukula, R. R., Anandam, J. L., Abdelnaby, A. A., Balch, G. C., Mansour, J. C., Yopp, A. C., Richardson, J. A. & Mendell, J. T., Dec 1 2014, In : Genes and Development. 28, 23, p. 2585-2590 6 p.

Research output: Contribution to journalArticle

41 Scopus citations
2013

Noncoding RNAs and cancer

Lieberman, J., Slack, F., Pandolfi, P. P., Chinnaiyan, A., Agami, R. & Mendell, J. T., Mar 28 2013, In : Cell. 153, 1, p. 9-10 2 p.

Research output: Contribution to journalEditorial

32 Scopus citations

When 19 is greater than 92

Zeitels, L. R. & Mendell, J. T., Oct 15 2013, In : eLife. 2013, 2, e01514.

Research output: Contribution to journalComment/debate

2012

A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts

Ribas, J., Ni, X., Castanares, M., Liu, M. M., Esopi, D., Yegnasubramanian, S., Rodriguez, R., Mendell, J. T. & Lupold, S. E., Aug 1 2012, In : Nucleic acids research. 40, 14, p. 6821-6833 13 p.

Research output: Contribution to journalArticle

56 Scopus citations

Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

Hsu, S. H., Wang, B., Kota, J., Yu, J., Costinean, S., Kutay, H., Yu, L., Bai, S., Perle, K. L., Chivukula, R. R., Mao, H., Wei, M., Clark, K. R., Mendell, J. R., Caligiuri, M. A., Jacob, S. T., Mendell, J. T. & Ghoshal, K., Aug 1 2012, In : Journal of Clinical Investigation. 122, 8, p. 2871-2883 13 p.

Research output: Contribution to journalArticle

474 Scopus citations

MicroRNAs in stress signaling and human disease

Mendell, J. T. & Olson, E. N., Mar 16 2012, In : Cell. 148, 6, p. 1172-1187 16 p.

Research output: Contribution to journalReview article

1015 Scopus citations
2011

KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation

Lee, Y. N., Brandal, S., Noel, P., Wentzel, E., Mendell, J. T., McDevitt, M. A., Kapur, R., Carter, M., Metcalfe, D. D. & Takemoto, C. M., Mar 31 2011, In : Blood. 117, 13, p. 3629-3640 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice

Pramanik, D., Campbell, N. R., Karikari, C., Chivukula, R., Kent, O. A., Mendell, J. T. & Maitra, A., Aug 1 2011, In : Molecular Cancer Therapeutics. 10, 8, p. 1470-1480 11 p.

Research output: Contribution to journalArticle

214 Scopus citations

Role of pri-miRNA tertiary structure in miR-17∼92 miRNA biogenesis

Chaulk, S. G., Thede, G. L., Kent, O. A., Xu, Z., Gesner, E. M., Veldhoen, R. A., Khanna, S. K., Goping, I. S., MacMillan, A. M., Mendell, J. T., Young, H. S., Fahlman, R. P. & Glover, J. N. M., Jan 1 2011, In : RNA Biology. 8, 6

Research output: Contribution to journalArticle

58 Scopus citations
2010

Absolute quantification of microrna from human and mouse tissue RNA using highly selective isotachophoretic focusing

Persat, A., Chivukula, R. R., Mendell, J. T. & Santiago, J. G., Dec 1 2010, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. p. 659-661 3 p. (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Identifying targets of miR-143 using a SILAC-based proteomic approach

Yang, Y., Chaerkady, R., Kandasamy, K., Huang, T. C., Selvan, L. D. N., Dwivedi, S. B., Kent, O. A., Mendell, J. T. & Pandey, A., Oct 1 2010, In : Molecular BioSystems. 6, 10, p. 1873-1882 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Myc: Maestro of MicroRNAs

Bui, T. V. & Mendell, J. T., Dec 1 2010, In : Genes and Cancer. 1, 6, p. 568-575 8 p.

Research output: Contribution to journalReview article

92 Scopus citations

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

Yamakuchi, M., Lotterman, C. D., Bao, C., Hruban, R. H., Karim, B., Mendell, J. T., Huso, D. & Lowenstein, C. J., Apr 6 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 14, p. 6334-6339 6 p.

Research output: Contribution to journalArticle

299 Scopus citations

Quantification of global microRNA abundance by selective isotachophoresis

Persat, A., Chivukula, R. R., Mendell, J. T. & Santiago, J. G., Dec 1 2010, In : Analytical chemistry. 82, 23, p. 9631-9635 5 p.

Research output: Contribution to journalArticle

32 Scopus citations

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

Kent, O. A., Chivukula, R. R., Mullendore, M., Wentzel, E. A., Feldmann, G., Lee, K. H., Liu, S., Leach, S. D., Maitra, A. & Mendell, J. T., Dec 15 2010, In : Genes and Development. 24, 24, p. 2754-2759 6 p.

Research output: Contribution to journalArticle

218 Scopus citations
2009

Abate and Switch: miR-145 in Stem Cell Differentiation

Chivukula, R. R. & Mendell, J. T., May 15 2009, In : Cell. 137, 4, p. 606-608 3 p.

Research output: Contribution to journalShort survey

32 Scopus citations

A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells

Kent, O. A., Mullendore, M., Wentzel, E. A., López-Romero, P., Tan, A. C., Alvarez, H., West, K., Ochs, M. F., Hidalgo, M., Arking, D. E., Maitra, A. & Mendell, J. T., Nov 1 2009, In : Cancer Biology and Therapy. 8, 21, p. 2013-2024 12 p.

Research output: Contribution to journalArticle

96 Scopus citations

Cell- cell contact globally activates microRNA biogenesis

Hwang, H. W., Wentzel, E. A. & Mendell, J. T., Apr 28 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 17, p. 7016-7021 6 p.

Research output: Contribution to journalArticle

104 Scopus citations

C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Gao, P., Tchernyshyov, I., Chang, T. C., Lee, Y. S., Kita, K., Ochi, T., Zeller, K. I., De Marzo, A. M., Van Eyk, J. E., Mendell, J. T. & Dang, C. V., Apr 9 2009, In : Nature. 458, 7239, p. 762-765 4 p.

Research output: Contribution to journalArticle

1203 Scopus citations

Epigenetic silencing of microRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer

Lee, K. H., Lotterman, C., Karikari, C., Omura, N., Feldmann, G., Habbe, N., Goggins, M. G., Mendell, J. T. & Maitra, A., May 2009, In : Pancreatology. 9, 3, p. 293-301 9 p.

Research output: Contribution to journalArticle

169 Scopus citations

Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach

Yang, Y., Chaerkady, R., Beer, M. A., Mendell, J. T. & Pandey, A., Mar 1 2009, In : Proteomics. 9, 5, p. 1374-1384 11 p.

Research output: Contribution to journalArticle

92 Scopus citations

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

Chang, T. C., Zeitels, L. R., Hwang, H. W., Chivukula, R. R., Wentzel, E. A., Dews, M., Jung, J., Gao, P., Dang, C. V., Beer, M. A., Thomas-Tikhonenko, A. & Mendella, J. T., Mar 3 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 9, p. 3384-3389 6 p.

Research output: Contribution to journalArticle

287 Scopus citations

MicroRNA miR-155 is a biomarker of early pancreatic neoplasia

Habbe, N., Koorstra, J. B. M., Mendell, J. T., Offerhaus, G. J., Ji, K. R., Feldmann, G., Mullendore, M. E., Goggins, M. G., Hong, S. M. & Maitra, A., Feb 15 2009, In : Cancer Biology and Therapy. 8, 4, p. 340-346 7 p.

Research output: Contribution to journalArticle

Open Access
241 Scopus citations

miR-21: An androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth

Ribas, J., Ni, X., Haffner, M., Wentzel, E. A., Salmasi, A. H., Chowdhury, W. H., Kudrolli, T. A., Yegnasubramanian, S., Luo, J., Rodriguez, R., Mendell, J. T. & Lupold, S. E., Oct 13 2009, In : Cancer research. 69, 18, p. 7165-7169 5 p.

Research output: Contribution to journalArticle

308 Scopus citations