• 1131 Citations
  • 7 h-Index
20002018
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Research Output 2000 2018

  • 1131 Citations
  • 7 h-Index
  • 12 Article
  • 1 Comment/debate
2018
1 Citation (Scopus)

EGF receptor and mTORC1 are novel therapeutic targets in nonseminomatous germ cell tumors

Chen, K., Fustino, N. J., Shukla, A. A., Stroup, E. K., Budhipramono, A., Ateek, C., Stuart, S. H., Yamaguchi, K., Kapur, P., Frazier, A. L., Lum, L., Looijenga, L. H. J., Laetsch, T. W., Rakheja, D. & Amatruda, J. F., May 1 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 1079-1089 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Germ Cell and Embryonal Neoplasms
Seminoma
Therapeutics
Embryonal Carcinoma
10 Citations (Scopus)

Mutations in microRNA processing genes in wilms tumors derepress the IGF2 regulator PLAG1

Chen, K., Stroup, E. K., Budhipramono, A., Rakheja, D., Nichols-Vinueza, D., Xu, L., Stuart, S. H., Shukla, A. A., Fraire, C., Mendell, J. T. & Amatruda, J. F., Aug 1 2018, In : Genes and Development. 32, 15-16, p. 996-1007 12 p.

Research output: Contribution to journalArticle

Wilms' Tumor Genes
Pleomorphic Adenoma
Wilms Tumor
Somatomedins
MicroRNAs
2017

Erratum: Publisher Correction: Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours

Rakheja, D., Chen, K. S., Liu, Y., Shukla, A. A., Schmid, V., Chang, T. C., Khokhar, S., Wickiser, J. E., Karandikar, N. J., Malter, J. S., Mendell, J. T. & Amatruda, J. F., Jan 1 2017, In : Nature communications. 8, 1 p.

Research output: Contribution to journalComment/debate

Open Access
biological evolution
Wilms Tumor
mutations
MicroRNAs
Tumors
2016
65 Citations (Scopus)

p53 genes function to restrain mobile elements

Wylie, A., Jones, A. E., D’Brot, A., Lu, W. J., Kurtz, P., Moran, J. V., Rakheja, D., Chen, K., Hammer, R. E., Comerford, S. A., Amatruda, J. F. & Abrams, J. M., Jan 1 2016, In : Genes and Development. 30, 1, p. 64-77 14 p.

Research output: Contribution to journalArticle

p53 Genes
Retroelements
Neoplasms
Long Interspersed Nucleotide Elements
Alleles
2014
1 Citation (Scopus)
Amikacin
Appointments and Schedules
Neoplasms
100 Citations (Scopus)

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours

Rakheja, D., Chen, K., Liu, Y., Shukla, A. A., Schmid, V., Chang, T-C., Khokhar, S., Wickiser, J. E., Karandikar, N. J., Malter, J. S., Mendell, J. T. & Amatruda, J. F., Sep 5 2014, In : Nature Communications. 2, 4802.

Research output: Contribution to journalArticle

biological evolution
Wilms Tumor
mutations
MicroRNAs
Tumors
2013
2 Citations (Scopus)

A Big Catch for Germ Cell Tumour Research

Chen, K. S. & Amatruda, J. F., Apr 2013, In : PLoS Genetics. 9, 4, e1003481.

Research output: Contribution to journalArticle

Zebrafish Proteins
animal disease models
Animal Disease Models
germ cell
Microtubule-Associated Proteins
27 Citations (Scopus)

DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors

Amatruda, J. F., Ross, J. A., Christensen, B., Fustino, N. J., Chen, K., Hooten, A. J., Nelson, H., Kuriger, J. K., Rakheja, D., Frazier, A. L. & Poynter, J. N., Jun 27 2013, In : BMC Cancer. 13, 313.

Research output: Contribution to journalArticle

Germ Cell and Embryonal Neoplasms
DNA Methylation
Methylation
Teratoma
Pediatrics
13 Citations (Scopus)

Hearing loss and vestibular dysfunction among children with cancer after receiving aminoglycosides

Chen, K. S., Bach, A., Shoup, A. & Winick, N. J., Nov 2013, In : Pediatric Blood and Cancer. 60, 11, p. 1772-1777 6 p.

Research output: Contribution to journalArticle

Aminoglycosides
Hearing Loss
Amikacin
Neoplasms
Hearing
2012

Hemolytic non-uremic syndrome

Chen, K. S., Neunert, C. E., Crary, S. E. & Buchanan, G. R., Jul 15 2012, In : Pediatric Blood and Cancer. 59, 1, p. 167-169 3 p.

Research output: Contribution to journalArticle

Hemolytic-Uremic Syndrome
Thrombotic Thrombocytopenic Purpura
Hemolytic Anemia
Phenotype
Therapeutics
2006
26 Citations (Scopus)

A large T cell invagination with CD2 enrichment resets receptor engagement in the immunological synapse

Singleton, K., Parvaze, N., Dama, K. R., Chen, K. S., Jennings, P., Purtic, B., Sjaastad, M. D., Gilpin, C., Davis, M. M. & Wülfing, C., Oct 1 2006, In : Journal of Immunology. 177, 7, p. 4402-4413 12 p.

Research output: Contribution to journalArticle

Immunological Synapses
T-Lymphocytes
Ligands
Phagocytosis
2001
885 Citations (Scopus)

Human natural killer cells: A unique innate immunoregulatory role for the CD56bright subset

Cooper, M. A., Fehniger, T. A., Turner, S. C., Chen, K. S., Ghaheri, B. A., Ghayur, T., Carson, W. E. & Caligiuri, M. A., May 15 2001, In : Blood. 97, 10, p. 3146-3151 6 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Cytokines
Monocytes
Innate Immunity
Interleukin-15
2000
1 Citation (Scopus)

Human natural killer cells: A unique innate immunoregulatory role for the CD56BRIGHT SUBSET

Cooper, M. A., Fehniger, T. A., Turner, S. C., Chen, K. S., Ghaheri, B. A., Carson, W. E. & Caligiuri, M. A., Dec 1 2000, In : Blood. 96, 11 PART II

Research output: Contribution to journalArticle

Natural Killer Cells
Cytokines
Monocytes
Granulocyte-Macrophage Colony-Stimulating Factor
Ionomycin