• 2032 Citations
  • 14 h-Index
19982019

Research output per year

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Research Output

  • 2032 Citations
  • 14 h-Index
  • 26 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Editorial
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Article
2019

Blocking monocytic myeloid-derived suppressor cell function via anti-DC-HIL/GpNMB antibody restores the in vitro integrity of T cells from cancer patients

Kobayashi, M., Chung, J. S., Beg, M. S., Arriaga, Y. E., Verma, U., Courtney, K. D., Mansour, J. C., Haley, B. B., Khan, S., Horiuchi, Y., Ramani, V., Harker, D., Gopal, P., Araghizadeh, F., Cruz, P. D. & Ariizumi, K., Jan 15 2019, In : Clinical Cancer Research. 25, 2, p. 828-838 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
1 Scopus citations
3 Scopus citations
2018

Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo

Courtney, K. D., Bezwada, D., Mashimo, T., Pichumani, K., Vemireddy, V., Funk, A. M., Wimberly, J., McNeil, S. S., Kapur, P., Lotan, Y., Margulis, V., Cadeddu, J. A., Pedrosa, I., DeBerardinis, R. J., Malloy, C. R., Bachoo, R. & Maher, E. A., Nov 6 2018, In : Cell Metabolism. 28, 5, p. 793-800.e2

Research output: Contribution to journalArticle

32 Scopus citations

MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG

Fets, L., Driscoll, P. C., Grimm, F., Jain, A., Nunes, P. M., Gounis, M., Doglioni, G., Papageorgiou, G., Ragan, T. J., Campos, S., Silva dos Santos, M., MacRae, J. I., O’Reilly, N., Wright, A. J., Benes, C. H., Courtney, K. D., House, D. & Anastasiou, D., Nov 1 2018, In : Nature Chemical Biology. 14, 11, p. 1032-1042 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Phase I dose-escalation trial of PT2385, a first-in-class hypoxia-inducible factor-2a antagonist in patients with previously treated advanced clear cell renal cell carcinoma

Courtney, K. D., Infante, J. R., Lam, E. T., Figlin, R. A., Rini, B. I., Brugarolas, J., Zojwalla, N. J., Lowe, A. M., Wang, K., Wallace, E. M., Josey, J. A. & Choueiri, T. K., Jan 1 2018, In : Journal of Clinical Oncology. 36, 9, p. 867-874 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy

Mohamad, O., Diaz de Leon, A., Schroeder, S., Leiker, A., Christie, A., Zhang-Velten, E., Trivedi, L., Khan, S., Desai, N. B., Laine, A., Albuquerque, K., Iyengar, P., Arriaga, Y., Courtney, K., Gerber, D. E., Hammers, H., Choy, H., Timmerman, R., Brugarolas, J. & Hannan, R., Mar 10 2018, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer

Li, J., Alyamani, M., Zhang, A., Chang, K. H., Berk, M., Li, Z., Zhu, Z., Petro, M., Magi-Galluzzi, C., Taplin, M. E., Garcia, J. A., Courtney, K., Klein, E. A. & Sharifi, N., Feb 13 2017, In : eLife. 6, e20183.

Research output: Contribution to journalArticle

35 Scopus citations

Natural history of 'second' biochemical failure after salvage radiation therapy for prostate cancer: A multi-institution study

Tumati, V., Jackson, W. C., Abugharib, A. E., Raj, G., Roehrborn, C., Lotan, Y., Courtney, K. D., Bagrodia, A., Gahan, J., Zumsteg, Z. S., Folkert, M. R., Laine, A. M., Hannan, R., Spratt, D. E. & Desai, N. B., 2017, (Accepted/In press) In : BJU International.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Targeting renal cell carcinoma with a HIF-2 antagonist

Chen, W., Hill, H., Christie, A., Kim, M. S., Holloman, E., Pavia-Jimenez, A., Homayoun, F., Ma, Y., Patel, N., Yell, P., Hao, G., Yousuf, Q., Joyce, A., Pedrosa, I., Geiger, H., Zhang, H., Chang, J., Gardner, K. H., Bruick, R. K., Reeves, C. & 14 others, Hwang, T. H., Courtney, K., Frenkel, E., Sun, X., Zojwalla, N., Wong, T., Rizzi, J. P., Wallace, E. M., Josey, J. A., Xie, Y., Xie, X. J., Kapur, P., McKay, R. M. & Brugarolas, J., 2016, In : Nature. 539, 7627, p. 112-117 6 p.

Research output: Contribution to journalArticle

193 Scopus citations
2015

A phase i study of everolimus and docetaxel in patients with castration-resistant prostate cancer

Courtney, K. D., Manola, J. B., Elfiky, A. A., Ross, R., Oh, W. K., Yap, J. T., Van Den Abbeele, A. D., Ryan, C. W., Beer, T. M., Loda, M., Priolo, C., Kantoff, P. & Taplin, M. E., Apr 1 2015, In : Clinical Genitourinary Cancer. 13, 2, p. 113-123 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Changing trends in utilization of neoadjuvant chemotherapy in muscle-invasive bladder cancer

Krabbe, L. M., Westerman, M. E., Margulis, V., Raj, G., Sagalowsky, A. I., Courtney, K. D., Arriaga, Y. E. & Lotan, Y., 2015, In : Canadian Journal of Urology. 22, 4, p. 7865-7875 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
2013

Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients

Emerling, B. M., Benes, C. H., Poulogiannis, G., Bell, E. L., Courtney, K., Liu, H., Choo-Wing, R., Bellinger, G., Tsukazawa, K. S., Brown, V., Signoretti, S., Soltoff, S. P. & Cantley, L. C., Feb 26 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 9, p. 3483-3488 6 p.

Research output: Contribution to journalArticle

35 Scopus citations
2012

Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis (Nature Chemical Biology (2012) 8 (839-847))

Anastasiou, D., Yu, Y., Israelsen, W. J., Jiang, J. K., Boxer, M. B., Hong, B. S., Tempel, W., Dimov, S., Shen, M., Jha, A., Yang, H., Mattaini, K. R., Metallo, C. M., Fiske, B. P., Courtney, K. D., Malstrom, S., Khan, T. M., Kung, C., Skoumbourdis, A. P., Veith, H. & 23 others, Southall, N., Walsh, M. J., Brimacombe, K. R., Leister, W., Lunt, S. Y., Johnson, Z. R., Yen, K. E., Kunii, K., Davidson, S. M., Christofk, H. R., Austin, C. P., Inglese, J., Harris, M. H., Asara, J. M., Stephanopoulos, G., Salituro, F. G., Jin, S., Dang, L., Auld, D. S., Park, H. W., Cantley, L. C., Thomas, C. J. & Vander Heiden, M. G., Dec 2012, In : Nature Chemical Biology. 8, 12, p. 1008 1 p.

Research output: Contribution to journalArticle

3 Scopus citations

Phase II trial of RAD001 and bicalutamide for castration-resistant prostate cancer

Nakabayashi, M., Werner, L., Courtney, K. D., Buckle, G., Oh, W. K., Bubley, G. J., Hayes, J. H., Weckstein, D., Elfiky, A., Sims, D. M., Kantoff, P. W. & Taplin, M. E., Dec 2012, In : BJU International. 110, 11, p. 1729-1735 7 p.

Research output: Contribution to journalArticle

56 Scopus citations

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Anastasiou, D., Yu, Y., Israelsen, W. J., Jiang, J. K., Boxer, M. B., Hong, B. S., Tempel, W., Dimov, S., Shen, M., Jha, A., Yang, H., Mattaini, K. R., Metallo, C. M., Fiske, B. P., Courtney, K. D., Malstrom, S., Khan, T. M., Kung, C., Skoumbourdis, A. P., Veith, H. & 23 others, Southall, N., Walsh, M. J., Brimacombe, K. R., Leister, W., Lunt, S. Y., Johnson, Z. R., Yen, K. E., Kunii, K., Davidson, S. M., Christofk, H. R., Austin, C. P., Inglese, J., Harris, M. H., Asara, J. M., Stephanopoulos, G., Salituro, F. G., Jin, S., Dang, L., Auld, D. S., Park, H. W., Cantley, L. C., Thomas, C. J. & Vander Heiden, M. G., 2012, In : Nature Chemical Biology. 8, 10, p. 839-847 9 p.

Research output: Contribution to journalArticle

337 Scopus citations

The evolving paradigm of second-line hormonal therapy options for castration-resistant prostate cancer

Courtney, K. D. & Taplin, M. E., May 2012, In : Current Opinion in Oncology. 24, 3, p. 272-277 6 p.

Research output: Contribution to journalArticle

19 Scopus citations
2010

The PI3K pathway as drug target in human cancer

Courtney, K. D., Corcoran, R. B. & Engelman, J. A., Feb 20 2010, In : Journal of Clinical Oncology. 28, 6, p. 1075-1083 9 p.

Research output: Contribution to journalArticle

869 Scopus citations

Updates on novel therapies for metastatic renal cell carcinoma

Courtney, K. D. & Choueiri, T. K., May 2010, In : Therapeutic Advances in Medical Oncology. 2, 3, p. 209-219 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2009

Optimizing recent advances in metastatic renal cell carcinoma

Courtney, K. D. & Choueiri, T. K., 2009, In : Current Oncology Reports. 11, 3, p. 218-226 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2008

PI3K Enters Beta-Testing

Shaywitz, A. J., Courtney, K. D., Patnaik, A. & Cantley, L. C., Sep 3 2008, In : Cell Metabolism. 8, 3, p. 179-181 3 p.

Research output: Contribution to journalArticle

6 Scopus citations
2007

Pulmonary thrombectomy in a patient with hemoglobin Nottingham

Memtsoudis, S. G., Lekowski, R. W., Rosenberger, P., Khalpey, Z., FitzGerald, D. J., Claypoole, V., Courtney, K. D., Landzberg, M. J., Bunn, H. F. & Shekar, P. S., 2007, In : Perfusion. 22, 4, p. 299-301 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2001

The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia

Stradal, T., Courtney, K. D., Rottner, K., Hahne, P., Small, J. V. & Pendergast, A. M., Jun 5 2001, In : Current Biology. 11, 11, p. 891-895 5 p.

Research output: Contribution to journalArticle

109 Scopus citations
2000

Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases

Quackenbush, R. C., Reuther, G. W., Miller, J. P., Courtney, K. D., Pear, W. S. & Pendergast, A. M., May 1 2000, In : Blood. 95, 9, p. 2913-2921 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Localization and phosphorylation of AbI-interactor proteins, Abi-1 and Abi-2, in the developing nervous system

Courtney, K. D., Grove, M., Vandongen, H., Vandongen, A., LaMantia, A. S. & Pendergast, A. M., 2000, In : Molecular and Cellular Neurosciences. 16, 3, p. 244-257 14 p.

Research output: Contribution to journalArticle

48 Scopus citations
1998

Oncogenic ABl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

Dai, Z., Quackenbush, R. C., Courtney, K. D., Grove, M., Cortez, D., Reuther, G. W. & Pendergast, A. M., May 15 1998, In : Genes and Development. 12, 10, p. 1415-1424 10 p.

Research output: Contribution to journalArticle

97 Scopus citations