• 2875 Citations
  • 32 h-Index
1980 …2019

Research output per year

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Research Output

  • 2875 Citations
  • 32 h-Index
  • 76 Article
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Article

2B4, a new member of the immunoglobulin gene superfamily, is expressed on murine dendritic epidermal T cells and plays a functional role in their killing of skin tumors

Schuhmachers, G., Ariizumi, K., Mathew, P. A., Bennett, M., Kumar, V. & Takashima, A., 1995, In : Journal of Investigative Dermatology. 105, 4, p. 592-596 5 p.

Research output: Contribution to journalArticle

50 Scopus citations

Activation of HIV in human skin by ultraviolet B radiation and its inhibition by NFκB blocking agents

Breuer-McHam, J., Simpson, E., Dougherty, I., Bonkobara, M., Ariizumi, K., Lewis, D. E., Dawson, D. B., Duvic, M. & Cruz, P. D., Dec 1 2001, In : Photochemistry and Photobiology. 74, 6, p. 805-810 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Activation of murine epidermal γδ T cells through surface 2B4

Schuhmachers, G., Ariizumi, K., Mathew, P. A., Bennett, M., Kumar, V. & Takashima, A., 1995, In : European Journal of Immunology. 25, 4, p. 1117-1120 4 p.

Research output: Contribution to journalArticle

45 Scopus citations

A novel mechanism of glucocorticoid-induced immune suppression: The inhibition of T cell-mediated terminal maturation of a murine dendritic cell line

Kitajima, T., Ariizumi, K., Bergstresser, P. R. & Takashima, A., Jul 1 1996, In : Journal of Clinical Investigation. 98, 1, p. 142-147 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function

Chung, J. S., Yudate, T., Tomihari, M., Akiyoshi, H., Cruz, P. D. & Ariizumi, K., Oct 15 2009, In : Journal of Immunology. 183, 8, p. 5190-5198 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Blocking monocytic myeloid-derived suppressor cell function via anti-DC-HIL/GpNMB antibody restores the in vitro integrity of T cells from cancer patients

Kobayashi, M., Chung, J. S., Beg, M. S., Arriaga, Y. E., Verma, U., Courtney, K. D., Mansour, J. C., Haley, B. B., Khan, S., Horiuchi, Y., Ramani, V., Harker, D., Gopal, P., Araghizadeh, F., Cruz, P. D. & Ariizumi, K., Jan 15 2019, In : Clinical Cancer Research. 25, 2, p. 828-838 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Canine epidermal langerhans cells express α and γ but not β chains of high-affinity IgE receptor

Bonkobara, M., Miyake, F., Yagihara, H., Yamada, O., Azakami, D., Washizu, T., Cruz, P. D. & Ariizumi, K., Aug 2005, In : Veterinary Research Communications. 29, 6, p. 499-505 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

CARD9 mediates dectin-2-induced IκBα kinase ubiquitination leading to activation of NF-κB in response to stimulation by the hyphal form of Candida albicans

Bi, L., Gojestani, S., Wu, W., Hsu, Y. M. S., Zhu, J., Ariizumi, K. & Lin, X., Aug 20 2010, In : Journal of Biological Chemistry. 285, 34, p. 25969-25977 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

Characterization of Kdap, a protein secreted by keratinocytes

Tsuchida, S., Bonkobara, M., McMillan, J. R., Akiyama, M., Yudate, T., Aragane, Y., Tezuka, T., Shimizu, H., Cruz, P. D. & Ariizumi, K., May 2004, In : Journal of Investigative Dermatology. 122, 5, p. 1225-1234 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cloning of a second dendritic cell-associated C-type lectin (dectin-2) and its alternatively spliced isoforms

Ariizumi, K., Shen, G. L., Shikano, S., Ritter, R., Zukas, P., Edelbaum, D., Morita, A. & Takashima, A., Apr 21 2000, In : Journal of Biological Chemistry. 275, 16, p. 11957-11963 7 p.

Research output: Contribution to journalArticle

129 Scopus citations

Colony-stimulating factor-1 secreted by fibroblasts promotes the growth of dendritic cell lines (XS series) derived from murine epidermis

Takashima, A., Edelbaum, D., Kitajima, T., Shadduck, R. K., Gilmore, G. L., Xu, S., Taylor, R. S., Bergstresser, P. R. & Ariizumi, K., 1995, In : Journal of Immunology. 154, 10, p. 5128-5135 8 p.

Research output: Contribution to journalArticle

55 Scopus citations
7 Scopus citations

Cytokine-dependent regulation of growth and maturation in murine epidermal dendritic cell lines

Xu, S., Ariizumi, K., Bergstresser, P. R. & Takashima, A., 1995, In : European Journal of Immunology. 25, 4, p. 1018-1024 7 p.

Research output: Contribution to journalArticle

63 Scopus citations

Cytokine-Mediated Communication between Dendritic Epidermal T Cells and Langerhans Cells: In Vitro Studies Using Cell Lines

Yokota, K., Ariizumi, K., Kitajima, T., Bergstresser, P. R., Street, N. E. & Takashima, A., Aug 15 1996, In : Journal of Immunology. 157, 4, p. 1529-1537 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells

Tomihari, M., Chung, J. S., Akiyoshi, H., Cruz, P. D. & Ariizumi, K., Jul 15 2010, In : Cancer Research. 70, 14, p. 5778-5787 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

DC-HIL+CD14+HLA-DRno/lowcells are a potential blood marker and therapeutic target for melanoma

Turrentine, J., Chung, J. S., Nezafati, K., Tamura, K., Harker-Murray, A., Huth, J. F., Sharma, R., Harker, D. B., Ariizumi, K. & Cruz, P. D., Nov 5 2014, In : Journal of Investigative Dermatology. 134, 11, p. 2839-2842 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

DC-HIL-expressing myelomonocytic cells are critical promoters of melanoma growth

Chung, J. S., Tamura, K., Cruz, P. D. & Ariizumi, K., Nov 5 2014, In : Journal of Investigative Dermatology. 134, 11, p. 2784-2794 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

DC-HIL is a negative regulator of T lymphocyte activation

Chung, J. S., Sato, K., Dougherty, I. I., Cruz, P. D. & Ariizumi, K., May 15 2007, In : Blood. 109, 10, p. 4320-4327 8 p.

Research output: Contribution to journalArticle

73 Scopus citations

Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor γ chain to induce innate immune responses

Sato, K., Yang, X. L., Yudate, T., Chung, J. S., Wu, J., Phelps, K. J., Kimberly, R. P., Underhill, D., Cruz, P. D. & Ariizumi, K., Dec 15 2006, In : Journal of Biological Chemistry. 281, 50, p. 38854-38866 13 p.

Research output: Contribution to journalArticle

295 Scopus citations
9 Scopus citations

Development of a Langerhans cell-targeted gene therapy format using a dendritic cell-specific promoter

Morita, A., Ariizumi, K., Ritter, R., Jester, J. V., Kumamoto, T., Johnston, S. A. & Takashima, A., 2001, In : Gene Therapy. 8, 22, p. 1729-1737 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Effect of silencer on polyomavirus DNA replication

Ariizumi, K., Takahashi, H., Nakamura, M. & Ariga, H., 1989, In : Molecular and Cellular Biology. 9, 9, p. 4026-4031 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Elements in the immunoglobulin heavy-chain enhancer directly regulate simian virus 40 ori-dependent DNA replication

Ariizumi, K., Ghosh, M. R. & Tucker, P. W., Sep 1993, In : Molecular and Cellular Biology. 13, 9, p. 5629-5636 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Epidermal Langerhans cell-targeted gene expression by a dectin-2 promoter

Bonkobara, M., Zukas, P. K., Shikano, S., Nakamura, S., Cruz, P. D. & Ariizumi, K., Dec 15 2001, In : Journal of Immunology. 167, 12, p. 6893-6900 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Establishment and characterization of antigen-presenting cell lines (XS series) derived from newborn mouse epidermis

Takashima, A., Xu, S., Ariizumi, K. & Bergstresser, P. R., 1995, In : Advances in Experimental Medicine and Biology. 378, p. 159-162 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Expansion of Myeloid-Derived Suppressor Cells in the Peripheral Blood and Lesional Skin of Cutaneous Lupus Patients

Florez-Pollack, S., Tseng, L. C., Kobayashi, M., Hosler, G. A., Ariizumi, K. & Chong, B., Jan 1 2018, (Accepted/In press) In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

2 Scopus citations

Expression of NF-κB in epidermis and the relationship between NF-κB activation and inhibition of keratinocyte growth

Takao, J., Yudate, T., Das, A., Shikano, S., Bonkobara, M., Ariizumi, K. & Cruz, P. D., Apr 1 2003, In : British Journal of Dermatology. 148, 4, p. 680-688 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Expression of the common cytokine receptor γ chain by murine dendritic cells including epidermal Langerhans cells

Mohamadzadeh, M., Ariizumi, K., Sugamura, K., Bergstresser, P. R. & Takashima, A., Jan 1996, In : European Journal of Immunology. 26, 1, p. 156-160 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Genomic scale analysis of the human keratinocyte response to broad-band ultraviolet-B irradiation

Takao, J., Ariizumi, K., Dougherty, I. I. & Cruz, P. D., 2002, In : Photodermatology Photoimmunology and Photomedicine. 18, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

50 Scopus citations

Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion

Tomihari, M., Hwang, S. H., Chung, J. S., Cruz, P. D. & Ariizumi, K., Jun 17 2009, In : Experimental Dermatology. 18, 7, p. 586-595 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Hydrogen peroxide mediates UV-induced impairment of antigen presentation in a murine epidermal-derived dendritic cell line

Caceres-Dittmar, G., Ariizumi, K., Xu Shan, S., Tapia, F. J., Bergstresser, P. R. & Takashima, A., Jul 1995, In : Photochemistry and Photobiology. 62, 1, p. 176-183 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Identification and cornification-related gene expression of canine keratinocyte differentiation-associated protein, Kdap

Yagihara, H., Terada, Y., Sugimoto, S., Hidaka, F., Yamada, O., Ono, K., Washizu, T., Ariizumi, K. & Bonkobara, M., Jul 2006, In : Veterinary Journal. 172, 1, p. 141-146 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Identification and expression profiling of a human C-type lectin, structurally homologous to mouse dectin-2

Gavino, A. C. P., Chung, J. S., Sato, K., Ariizumi, K. & Cruz, P. D., Apr 1 2005, In : Experimental Dermatology. 14, 4, p. 281-288 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Identification and gene expression of bovine C-type lectin dectin-2

Bonkobara, M., Hoshino, M., Yagihara, H., Tamura, K., Isotani, M., Tanaka, Y., Washizu, T. & Ariizumi, K., Mar 15 2006, In : Veterinary Immunology and Immunopathology. 110, 1-2, p. 179-186 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Identification of a human homologue of the dendritic cell-associated C-type lectin-1, dectin-1

Yokota, K., Takashima, A., Bergstresser, P. R. & Ariizumi, K., Jul 11 2001, In : Gene. 272, 1-2, p. 51-60 10 p.

Research output: Contribution to journalArticle

75 Scopus citations

Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning

Ariizumi, K., Shen, G. L., Shikano, S., Xu, S., Ritter, R., Kumamoto, T., Edelbaum, D., Morita, A., Bergstresser, P. R. & Takashima, A., Jun 30 2000, In : Journal of Biological Chemistry. 275, 26, p. 20157-20167 11 p.

Research output: Contribution to journalArticle

339 Scopus citations

Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes

Bonkobara, M., Das, A., Takao, J., Cruz, P. D. & Ariizumi, K., Apr 1 2003, In : British Journal of Dermatology. 148, 4, p. 654-664 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

IFN-γ-dependent IL-7 gene regulation in keratinocytes

Ariizumi, K., Meng, Y., Bergstresser, P. R. & Takashima, A., 1995, In : Journal of Immunology. 154, 11, p. 6031-6039 9 p.

Research output: Contribution to journalArticle

62 Scopus citations

IL-7 upregulates T cell receptor/CD3 expression by cultured dendritic epidermal T cells

Ono, M., Ariizumi, K., Bergstresser, P. R. & Takashima, A., Feb 1996, In : Journal of Dermatological Science. 11, 2, p. 89-96 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Immunization with a lentivector that targets tumor antigen expression to dendritic cells induces potent CD8+ and CD4+ T-cell responses

Lopes, L., Dewannieux, M., Gileadi, U., Bailey, R., Ikeda, Y., Whittaker, C., Collin, M. P., Cerundolo, V., Tomihari, M., Ariizumi, K. & Collins, M. K., Jan 2008, In : Journal of Virology. 82, 1, p. 86-95 10 p.

Research output: Contribution to journalArticle

56 Scopus citations
53 Scopus citations

Inhibition of T-cell activation by syndecan-4 is mediated by CD148 through protein tyrosine phosphatase activity

Chung, J. S., Cruz, P. D. & Ariizumi, K., Jun 2011, In : European Journal of Immunology. 41, 6, p. 1794-1799 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Interleukin-1β converting enzyme in murine Langerhans cells and epidermal-derived dendritic cell lines

Ariizumi, K., Kitajima, T., Bergstresser, P. R. & Takashima, A., Aug 1995, In : European Journal of Immunology. 25, 8, p. 2137-2141 5 p.

Research output: Contribution to journalArticle

48 Scopus citations

Interleukin-7-dependent interaction of dendritic epidermal t cells with keratinocytes

Takashima, A., Matsue, H., Bergstresser, P. R. & Ariizumi, K., 1995, In : Journal of Investigative Dermatology. 105, 1 SUPPL.

Research output: Contribution to journalArticle

28 Scopus citations

Involvement of dectin-2 in ultraviolet radiation-induced tolerance

Aragane, Y., Maeda, A., Schwarz, A., Tezuka, T., Ariizumi, K. & Schwarz, T., Oct 1 2003, In : Journal of Immunology. 171, 7, p. 3801-3807 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

Langerhans cell interaction with epidermal y& t cells

Yokota, K., Ariizumi, K., Kiaiima, T., Berestresser, P. R. & Takashima, 1996, In : FASEB Journal. 10, 6

Research output: Contribution to journalArticle

Melanoma-Derived Soluble DC-HIL/GPNMB Promotes Metastasis by Excluding T-Lymphocytes from the Pre-Metastatic Niches

Ramani, V., Teshima, T., Tamura, K., Chung, J. S., Kobayashi, M., Cruz, P. D. & Ariizumi, K., Jan 1 2018, (Accepted/In press) In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Mitogenic and hemagglutinating activities in culture filtrates of bacteria

Ariizumi, K., Oishi, K. & Aida, K., Jan 1 1980, In : Journal of General and Applied Microbiology. 26, 3, p. 239-244 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
130 Scopus citations

Myeloid-Derived Suppressor Cells in Psoriasis Are an Expanded Population Exhibiting Diverse T-Cell–Suppressor Mechanisms

Cao, L. Y., Chung, J. S., Teshima, T., Feigenbaum, L., Cruz, P. D., Jacobe, H., Chong, B. & Ariizumi, K., Sep 1 2016, In : Journal of Investigative Dermatology. 136, 9, p. 1801-1810 10 p.

Research output: Contribution to journalArticle

15 Scopus citations