Li Liu

  • 2466 Citations
  • 26 h-Index
19982019

Research output per year

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Research Output

  • 2466 Citations
  • 26 h-Index
  • 58 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Review article
2019

Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression

Kalainayakan, S. P., Ghosh, P., Dey, S., Fitzgerald, K. E., Sohoni, S., Konduri, P. C., Garrossian, M., Liu, L. & Zhang, L., Dec 1 2019, In : Scientific Reports. 9, 1, 1405.

Research output: Contribution to journalArticle

Open Access
2018

Synthesis of fluorescent polythiophene dots

Liu, Z., Nahhas, A., Liu, L., Ada, E., Zhang, X. & Manohar, S. K., Jan 1 2018, In : Journal of Nanomaterials. 2018, 8987348.

Research output: Contribution to journalArticle

1 Scopus citations

The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells

Dey, S., Kumari, S., Kalainayakan, S. P., Campbell, J., Ghosh, P., Zhou, H., FitzGerald, K. E., Li, M., Mason, R. P., Zhang, L. & Liu, L., Jan 1 2018, In : Oncotarget. 9, 3, p. 4090-4101 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
2017

Aerosol delivery of stabilized polyester-siRNA nanoparticles to silence gene expression in orthotopic lung tumors

Yan, Y., Zhou, K., Xiong, H., Miller, J. B., Motea, E. A., Boothman, D. A., Liu, L. & Siegwart, D. J., Feb 1 2017, In : Biomaterials. 118, p. 84-93 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Interactions of Renal-Clearable Gold Nanoparticles with Tumor Microenvironments: Vasculature and Acidity Effects

Yu, M., Zhou, C., Liu, L., Zhang, S., Sun, S., Hankins, J. D., Sun, X. & Zheng, J., Apr 3 2017, In : Angewandte Chemie - International Edition. 56, 15, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Synthesis of a cell penetrating peptide modified superparamagnetic iron oxide and MRI detection of bladder cancer

Ding, C., Wu, K., Wang, W., Guan, Z., Wang, L., Wang, X., Wang, R., Liu, L. & Fan, J., 2017, In : Oncotarget. 8, 3, p. 4718-4729 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

TRF/miR-1280 suppresses stem cell-like cells and metastasis in colorectal cancer

Huang, B., Yang, H., Cheng, X., Wang, D., Fu, S., Shen, W., Zhang, Q., Zhang, L., Xue, Z., Li, Y., Da, Y., Yang, Q., Li, Z., Liu, L., Qiao, L., Kong, Y., Yao, Z., Zhao, P., Li, M. & Zhang, R., Jun 15 2017, In : Cancer Research. 77, 12, p. 3194-3206 13 p.

Research output: Contribution to journalArticle

27 Scopus citations
2016

Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents

Devkota, L., Lin, C. M., Strecker, T. E., Wang, Y., Tidmore, J. K., Chen, Z., Guddneppanavar, R., Jelinek, C. J., Lopez, R., Liu, L., Hamel, E., Mason, R. P., Chaplin, D. J., Trawick, M. L. & Pinney, K. G., Mar 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 5, p. 938-956 19 p.

Research output: Contribution to journalArticle

22 Scopus citations

Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells

Yan, Y., Liu, L., Xiong, H., Miller, J. B., Zhou, K., Kos, P., Huffman, K. E., Elkassih, S., Norman, J. W., Carstens, R., Kim, J., Minna, J. D. & Siegwart, D. J., Sep 27 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. E5702-E5710

Research output: Contribution to journalArticle

38 Scopus citations

Inorganic phosphate-triggered release of anti-cancer arsenic trioxide from a self-delivery system: An in vitro and in vivo study

Chen, F. Y., Yi, J. W., Gu, Z. J., Tang, B. B., Li, J. Q., Li, L., Kulkarni, P., Liu, L., Mason, R. P. & Tang, Q., Mar 21 2016, In : Nanoscale. 8, 11, p. 6094-6100 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Investigation of the strategies for targeting of the afterglow nanoparticles to tumor cells

Rashidi, L. H., Homayoni, H., Zou, X., Liu, L. & Chen, W., Mar 1 2016, In : Photodiagnosis and Photodynamic Therapy. 13, p. 244-254 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation

Cao, J., Campbell, J., Liu, L., Mason, R. P. & Lippert, A. R., May 3 2016, In : Analytical Chemistry. 88, 9, p. 4995-5002 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Latex carrier for improving protoporphyrin IX for photodynamic therapy

Bui, B., Liu, L. & Chen, W., Jun 1 2016, In : Photodiagnosis and Photodynamic Therapy. 14, p. 159-165 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Synthesis and biological evaluation of benzocyclooctene-based and indene-based anticancer agents that function as inhibitors of tubulin polymerization

Herdman, C. A., Strecker, T. E., Tanpure, R. P., Chen, Z., Winters, A., Gerberich, J., Liu, L., Hamel, E., Mason, R. P., Chaplin, D. J., Trawick, M. L. & Pinney, K. G., 2016, In : MedChemComm. 7, 12, p. 2418-2427 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
2015

Click-chemistry strategy for labeling antibodies with copper-64 via a cross-bridged tetraazamacrocyclic chelator scaffold

Kumar, A., Hao, G., Liu, L., Ramezani, S., Hsieh, J. T., Öz, O. K. & Sun, X., Apr 15 2015, In : Bioconjugate Chemistry. 26, 4, p. 782-789 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
19 Scopus citations

One-pot synthesis of functional poly(amino ester sulfide)s and utility in delivering pDNA and siRNA

Yan, Y., Xue, L., Miller, J. B., Zhou, K., Kos, P., Elkassih, S., Liu, L., Nagai, A., Xiong, H. & Siegwart, D. J., Jan 3 2015, In : Polymer (United Kingdom). 72, p. 271-280 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization

Herdman, C. A., Devkota, L., Lin, C. M., Niu, H., Strecker, T. E., Lopez, R., Liu, L., George, C. S., Tanpure, R. P., Hamel, E., Chaplin, D. J., Mason, R. P., Trawick, M. L. & Pinney, K. G., Dec 15 2015, In : Bioorganic and Medicinal Chemistry. 23, 24, p. 7497-7520 24 p.

Research output: Contribution to journalArticle

13 Scopus citations

The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts

Strecker, T. E., Odutola, S. O., Lopez, R., Cooper, M. S., Tidmore, J. K., Charlton-Sevcik, A. K., Li, L., MacDonough, M. T., Hadimani, M. B., Ghatak, A., Liu, L., Chaplin, D. J., Mason, R. P., Pinney, K. G. & Trawick, M. L., Dec 1 2015, In : Cancer Letters. 369, 1, p. 229-241 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
2014

Development of intrinsically photoluminescent and photostable polylactones

Xie, Z., Zhang, Y., Liu, L., Weng, H., Mason, R. P., Tang, L., Nguyen, K. T., Hsieh, J. T. & Yang, J., Jul 9 2014, In : Advanced Materials. 26, 26, p. 4491-4496 6 p.

Research output: Contribution to journalArticle

40 Scopus citations
6 Scopus citations

Red-shifted emission from 1,2-dioxetane-based chemiluminescent reactions

Park, J. Y., Gunpat, J., Liu, L., Edwards, B., Christie, A., Xie, X. J., Kricka, L. J. & Mason, R. P., Sep 1 2014, In : Luminescence. 29, 6, p. 553-558 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2013

19F-MRS/1H-MRI dual-1 of β-galactosidase activity

Yu, J. X., Kodibagkar, V. D., Liu, L., Zhang, Z., Magnusson, J. & Liu, Y., May 1 2013, In : Chemical Science. 4, 5, p. 2132-2142 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

19F-MRS/1H-MRI dual-function probe for detection of β-galactosidase activity

Yu, J. X., Kodibagkar, V. D., Liu, L., Zhang, Z., Magnusson, J. & Liu, Y., Apr 2 2013, In : Chemical Science. 4, 5, p. 2132-2142 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Lupus-prone strains vary in susceptibility to antibody-mediated end organ disease

Xie, C., Du, Y., Kumar, K., Li, L., Han, J., Liu, K., Zhou, X. J. & Mohan, C., Apr 1 2013, In : Genes and Immunity. 14, 3, p. 170-178 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Novel S-Gal® analogs as 1H MRI reporters for in vivo detection of β-galactosidase

Gulaka, P. K., Yu, J. X., Liu, L., Mason, R. P. & Kodibagkar, V. D., Jul 1 2013, In : Magnetic Resonance Imaging. 31, 6, p. 1006-1011 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent

Hadimani, M. B., MacDonough, M. T., Ghatak, A., Strecker, T. E., Lopez, R., Sriram, M., Nguyen, B. L., Hall, J. J., Kessler, R. J., Shirali, A. R., Liu, L., Garner, C. M., Pettit, G. R., Hamel, E., Chaplin, D. J., Mason, R. P., Trawick, M. L. & Pinney, K. G., Sep 27 2013, In : Journal of Natural Products. 76, 9, p. 1668-1678 11 p.

Research output: Contribution to journalArticle

35 Scopus citations
2012
22 Scopus citations

Dual 19F/ 1H MR gene reporter molecules for in vivo detection of β-galactosidase

Yu, J. X., Kodibagkar, V. D., Hallac, R. R., Liu, L. & Mason, R. P., Mar 21 2012, In : Bioconjugate Chemistry. 23, 3, p. 596-603 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Dual-modality, dual-functional nanoprobes for cellular and molecular imaging

Menon, J. U., Gulaka, P. K., McKay, M. A., Geethanath, S., Liu, L. & Kodibagkar, V. D., Dec 1 2012, In : Theranostics. 2, 12, p. 1199-1207 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Innovative applications of reporter genes and gene reporters in prostate cancer

Liu, L., Alhasan, M. K., Cui, W., Magnusson, J. & Mason, R. P., Dec 1 2012, Prostate Cancer Cells: Detection, Growth and Treatment. Nova Science Publishers, Inc., p. 1-14 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Murine lupus strains differentially model unique facets of human lupus serology

Li, L., Nukala, S., Du, Y., Han, J., Liu, K., Hutcheson, J., Pathak, S., Li, Q. & Mohan, C., May 1 2012, In : Clinical and Experimental Immunology. 168, 2, p. 178-185 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Novel Fe 3+-Based 1H MRI β-galactosidase reporter molecules

Yu, J. X., Gulaka, P. K., Liu, L., Kodibagkar, V. D. & Mason, R. P., May 1 2012, In : ChemPlusChem. 77, 5, p. 370-378 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Serial Non-Invasive Monitoring of Renal Disease Following Immune-Mediated Injury Using Near-Infrared Optical Imaging

Du, Y., An, S., Liu, L., Li, L., Zhou, X. J., Mason, R. P. & Mohan, C., Sep 26 2012, In : PloS one. 7, 9, e43941.

Research output: Contribution to journalArticle

7 Scopus citations

Tubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenografts

Liu, L., Beck, H., Wang, X., Hsieh, H. P., Mason, R. P. & Liu, X., Aug 24 2012, In : PloS one. 7, 8, e43314.

Research output: Contribution to journalArticle

23 Scopus citations
2011

A perspective on vascular disrupting agents that interact with tubulin: Preclinical tumor imaging and biological assessment

Mason, R. P., Zhao, D., Liu, L., Trawick, M. L. & Pinney, K. G., Apr 1 2011, In : Integrative Biology. 3, 4, p. 375-387 13 p.

Research output: Contribution to journalReview article

77 Scopus citations
2010
48 Scopus citations

S-Gal®, a novel1H MRI reporter for β-galactosidase

Cui, W., Liu, L., Kodibagkar, V. D. & Mason, R. P., Jul 1 2010, In : Magnetic resonance in medicine. 64, 1, p. 65-71 7 p.

Research output: Contribution to journalArticle

34 Scopus citations
2009

Cell encapsulation and oxygenation in nanoporous microcontainers

Gimi, B., Kwon, J., Liu, L., Su, Y., Nemani, K., Trivedi, K., Cui, Y., Vachha, B., Mason, R., Hu, W. & Lee, J. B., Dec 1 2009, In : Biomedical Microdevices. 11, 6, p. 1205-1212 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Development of aliphatic biodegradable photoluminescent polymers

Yang, J., Zhang, Y., Gautam, S., Liu, L., Dey, J., Chen, W., Mason, R. P., Serrano, C. A., Schug, K. A. & Tang, L., Jun 23 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 25, p. 10086-10091 6 p.

Research output: Contribution to journalArticle

145 Scopus citations
16 Scopus citations

The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis

Li, Q. Z., Zhou, J., Yang, R., Yan, M., Ye, Q., Liu, K., Liu, S., Shao, X., Li, L., Zhou, X. J., Wakeland, E. K. & Mohan, C., Mar 6 2009, In : Genes and Immunity. 10, 5, p. 503-508 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
2008

A 19F-NMR approach using reporter molecule pairs to assess β-galactosidase in human xenograft tumors in vivo

Yu, J. X., Kodibagkar, V. D., Liu, L. & Mason, R. P., Aug 1 2008, In : NMR in biomedicine. 21, 7, p. 704-712 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Evaluation of red CdTe and near infrared CdHgTe quantum dots by fluorescent imaging

Zhang, J., Su, J., Liu, L., Huang, Y. & Mason, R. P., Mar 1 2008, In : Journal of Nanoscience and Nanotechnology. 8, 3, p. 1155-1159 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Exploring feasibility of multicolored CdTe quantum dots for in Vitro and in Vivo fluorescent imaging

Su, J., Zhang, J., Liu, L., Huang, Y. & Mason, R. P., Mar 1 2008, In : Journal of Nanoscience and Nanotechnology. 8, 3, p. 1174-1177 4 p.

Research output: Contribution to journalArticle

41 Scopus citations

In vitro and in vivo assessment of CdTe and CdHgTe toxicity and clearance

Liu, L., Zhang, J., Su, X. & Mason, R. P., Dec 1 2008, In : Journal of biomedical nanotechnology. 4, 4, p. 524-528 5 p.

Research output: Contribution to journalArticle

39 Scopus citations
2007
49 Scopus citations
2006

Imaging β-galactosidase activity using 19F chemical shift imaging of LacZ gene-reporter molecule 2-fluoro-4-nitrophenol-β-d-galactopyranoside

Kodibagkar, V. D., Yu, J., Liu, L., Hetherington, H. P. & Mason, R. P., Sep 1 2006, In : Magnetic Resonance Imaging. 24, 7, p. 959-962 4 p.

Research output: Contribution to journalArticle

60 Scopus citations

Phosphorylation of IκB-β is necessary for neuronal survival

Liu, L. & D'Mello, S. R., Jan 20 2006, In : Journal of Biological Chemistry. 281, 3, p. 1506-1515 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
39 Scopus citations