Li Liu

  • 2425 Citations
  • 26 h-Index
19982019
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Research Output 1998 2019

  • 2425 Citations
  • 26 h-Index
  • 60 Article
  • 1 Chapter
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Article
2019

Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression

Kalainayakan, S. P., Ghosh, P., Dey, S., Fitzgerald, K. E., Sohoni, S., Konduri, P. C., Garrossian, M., Liu, L. & Zhang, L., Dec 1 2019, In : Scientific Reports. 9, 1, 1405.

Research output: Contribution to journalArticle

Open Access
Oxidative Phosphorylation
Heme
Respiration
Lung
Non-Small Cell Lung Carcinoma
2018
1 Citation (Scopus)

Synthesis of fluorescent polythiophene dots

Liu, Z., Nahhas, A., Liu, L., Ada, E., Zhang, X. & Manohar, S. K., Jan 1 2018, In : Journal of Nanomaterials. 2018, 8987348.

Research output: Contribution to journalArticle

Polymers
hydrazine
Thiophenes
Hydrazine
Thiophene
10 Citations (Scopus)

The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells

Dey, S., Kumari, S., Kalainayakan, S. P., Campbell, J., Ghosh, P., Zhou, H., FitzGerald, K. E., Li, M., Mason, R. P., Zhang, L. & Liu, L., Jan 1 2018, In : Oncotarget. 9, 3, p. 4090-4101 12 p.

Research output: Contribution to journalArticle

Heme
Blood Vessels
Phosphates
Neoplasms
Proteins
2017
24 Citations (Scopus)

Aerosol delivery of stabilized polyester-siRNA nanoparticles to silence gene expression in orthotopic lung tumors

Yan, Y., Zhou, K., Xiong, H., Miller, J. B., Motea, E. A., Boothman, D. A., Liu, L. & Siegwart, D. J., Feb 1 2017, In : Biomaterials. 118, p. 84-93 10 p.

Research output: Contribution to journalArticle

Polyesters
Aerosols
Gene expression
Nanoparticles
Small Interfering RNA
22 Citations (Scopus)

Interactions of Renal-Clearable Gold Nanoparticles with Tumor Microenvironments: Vasculature and Acidity Effects

Yu, M., Zhou, C., Liu, L., Zhang, S., Sun, S., Hankins, J. D., Sun, X. & Zheng, J., Apr 3 2017, In : Angewandte Chemie - International Edition. 56, 15, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

Acidity
Gold
Tumors
Nanoparticles
Medical nanotechnology
9 Citations (Scopus)

Synthesis of a cell penetrating peptide modified superparamagnetic iron oxide and MRI detection of bladder cancer

Ding, C., Wu, K., Wang, W., Guan, Z., Wang, L., Wang, X., Wang, R., Liu, L. & Fan, J., 2017, In : Oncotarget. 8, 3, p. 4718-4729 12 p.

Research output: Contribution to journalArticle

Cell-Penetrating Peptides
Urinary Bladder Neoplasms
Nanoparticles
Contrast Media
Urinary Bladder
25 Citations (Scopus)

TRF/miR-1280 suppresses stem cell-like cells and metastasis in colorectal cancer

Huang, B., Yang, H., Cheng, X., Wang, D., Fu, S., Shen, W., Zhang, Q., Zhang, L., Xue, Z., Li, Y., Da, Y., Yang, Q., Li, Z., Liu, L., Qiao, L., Kong, Y., Yao, Z., Zhao, P., Li, M. & Zhang, R., Jun 15 2017, In : Cancer Research. 77, 12, p. 3194-3206 13 p.

Research output: Contribution to journalArticle

Transfer RNA
Colorectal Neoplasms
Stem Cells
Neoplasm Metastasis
Neoplastic Stem Cells
2016
21 Citations (Scopus)

Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents

Devkota, L., Lin, C. M., Strecker, T. E., Wang, Y., Tidmore, J. K., Chen, Z., Guddneppanavar, R., Jelinek, C. J., Lopez, R., Liu, L., Hamel, E., Mason, R. P., Chaplin, D. J., Trawick, M. L. & Pinney, K. G., Mar 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 5, p. 938-956 19 p.

Research output: Contribution to journalArticle

Prodrugs
Leucyl Aminopeptidase
Blood Vessels
Cytotoxicity
Amino Acids
36 Citations (Scopus)

Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells

Yan, Y., Liu, L., Xiong, H., Miller, J. B., Zhou, K., Kos, P., Huffman, K. E., Elkassih, S., Norman, J. W., Carstens, R., Kim, J., Minna, J. D. & Siegwart, D. J., Sep 27 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. E5702-E5710

Research output: Contribution to journalArticle

Polyesters
Small Interfering RNA
Lung Neoplasms
Nanoparticles
Neoplasms
10 Citations (Scopus)

Inorganic phosphate-triggered release of anti-cancer arsenic trioxide from a self-delivery system: An in vitro and in vivo study

Chen, F. Y., Yi, J. W., Gu, Z. J., Tang, B. B., Li, J. Q., Li, L., Kulkarni, P., Liu, L., Mason, R. P. & Tang, Q., Mar 21 2016, In : Nanoscale. 8, 11, p. 6094-6100 7 p.

Research output: Contribution to journalArticle

Arsenic
Drug delivery
Tumors
Phosphates
Cells
7 Citations (Scopus)

Investigation of the strategies for targeting of the afterglow nanoparticles to tumor cells

Rashidi, L. H., Homayoni, H., Zou, X., Liu, L. & Chen, W., Mar 1 2016, In : Photodiagnosis and Photodynamic Therapy. 13, p. 244-254 11 p.

Research output: Contribution to journalArticle

Folic Acid
Nanoparticles
Neoplasms
Breast Neoplasms
Integrins
47 Citations (Scopus)

In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation

Cao, J., Campbell, J., Liu, L., Mason, R. P. & Lippert, A. R., May 3 2016, In : Analytical Chemistry. 88, 9, p. 4995-5002 8 p.

Research output: Contribution to journalArticle

Nitroreductases
Oxygenation
Tumors
Tissue
Oxygen
3 Citations (Scopus)

Latex carrier for improving protoporphyrin IX for photodynamic therapy

Bui, B., Liu, L. & Chen, W., Jun 1 2016, In : Photodiagnosis and Photodynamic Therapy. 14, p. 159-165 7 p.

Research output: Contribution to journalArticle

Latex
Photochemotherapy
Styrene
Singlet Oxygen
protoporphyrin IX
16 Citations (Scopus)

Synthesis and biological evaluation of benzocyclooctene-based and indene-based anticancer agents that function as inhibitors of tubulin polymerization

Herdman, C. A., Strecker, T. E., Tanpure, R. P., Chen, Z., Winters, A., Gerberich, J., Liu, L., Hamel, E., Mason, R. P., Chaplin, D. J., Trawick, M. L. & Pinney, K. G., 2016, In : MedChemComm. 7, 12, p. 2418-2427 10 p.

Research output: Contribution to journalArticle

Tubulin Modulators
Antineoplastic Agents
Blood Vessels
Prodrugs
Salts
2015
15 Citations (Scopus)

Click-chemistry strategy for labeling antibodies with copper-64 via a cross-bridged tetraazamacrocyclic chelator scaffold

Kumar, A., Hao, G., Liu, L., Ramezani, S., Hsieh, J. T., Öz, O. K. & Sun, X., Apr 15 2015, In : Bioconjugate Chemistry. 26, 4, p. 782-789 8 p.

Research output: Contribution to journalArticle

Click Chemistry
Chelating Agents
Antibodies
Scaffolds
Labeling
18 Citations (Scopus)
Optical Imaging
Heterografts
Brain Neoplasms
Blood Vessels
Neoplasms
9 Citations (Scopus)

One-pot synthesis of functional poly(amino ester sulfide)s and utility in delivering pDNA and siRNA

Yan, Y., Xue, L., Miller, J. B., Zhou, K., Kos, P., Elkassih, S., Liu, L., Nagai, A., Xiong, H. & Siegwart, D. J., Jan 3 2015, In : Polymer (United Kingdom). 72, p. 271-280 10 p.

Research output: Contribution to journalArticle

Sulfides
Small Interfering RNA
Esters
Polymers
Gene therapy
13 Citations (Scopus)

Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization

Herdman, C. A., Devkota, L., Lin, C. M., Niu, H., Strecker, T. E., Lopez, R., Liu, L., George, C. S., Tanpure, R. P., Hamel, E., Chaplin, D. J., Mason, R. P., Trawick, M. L. & Pinney, K. G., Dec 15 2015, In : Bioorganic and Medicinal Chemistry. 23, 24, p. 7497-7520 24 p.

Research output: Contribution to journalArticle

Tubulin Modulators
Cytotoxicity
Inhibitory Concentration 50
Blood Vessels
Bearings (structural)
14 Citations (Scopus)

The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts

Strecker, T. E., Odutola, S. O., Lopez, R., Cooper, M. S., Tidmore, J. K., Charlton-Sevcik, A. K., Li, L., MacDonough, M. T., Hadimani, M. B., Ghatak, A., Liu, L., Chaplin, D. J., Mason, R. P., Pinney, K. G. & Trawick, M. L., Dec 1 2015, In : Cancer Letters. 369, 1, p. 229-241 13 p.

Research output: Contribution to journalArticle

Human Umbilical Vein Endothelial Cells
Prodrugs
Heterografts
Blood Vessels
Endothelial Cells
2014
40 Citations (Scopus)

Development of intrinsically photoluminescent and photostable polylactones

Xie, Z., Zhang, Y., Liu, L., Weng, H., Mason, R. P., Tang, L., Nguyen, K. T., Hsieh, J. T. & Yang, J., Jul 9 2014, In : Advanced Materials. 26, 26, p. 4491-4496 6 p.

Research output: Contribution to journalArticle

Biodegradable polymers
Drug delivery
Nanoparticles
Imaging techniques
Degradation
6 Citations (Scopus)
Molecular imaging
Molecular Imaging
Indocyanine Green
Heterografts
Blood Vessels
10 Citations (Scopus)

Red-shifted emission from 1,2-dioxetane-based chemiluminescent reactions

Park, J. Y., Gunpat, J., Liu, L., Edwards, B., Christie, A., Xie, X. J., Kricka, L. J. & Mason, R. P., Sep 1 2014, In : Luminescence. 29, 6, p. 553-558 6 p.

Research output: Contribution to journalArticle

Chemiluminescence
Luminescence
Fluorophores
Tissue
Biological Phenomena
2013
11 Citations (Scopus)

19F-MRS/1H-MRI dual-1 of β-galactosidase activity

Yu, J. X., Kodibagkar, V. D., Liu, L., Zhang, Z., Magnusson, J. & Liu, Y., May 2013, In : Chemical Science. 4, 5, p. 2132-2142 11 p.

Research output: Contribution to journalArticle

Galactosidases
Magnetic resonance imaging
Molecular biology
Chemical shift
Gene expression
3 Citations (Scopus)

19F-MRS/1H-MRI dual-function probe for detection of β-galactosidase activity

Yu, J. X., Kodibagkar, V. D., Liu, L., Zhang, Z., Magnusson, J. & Liu, Y., Apr 2 2013, In : Chemical Science. 4, 5, p. 2132-2142 11 p.

Research output: Contribution to journalArticle

Galactosidases
Magnetic resonance imaging
Molecular biology
Chemical shift
Gene expression
4 Citations (Scopus)

Lupus-prone strains vary in susceptibility to antibody-mediated end organ disease

Xie, C., Du, Y., Kumar, K., Li, L., Han, J., Liu, K., Zhou, X. J. & Mohan, C., Apr 2013, In : Genes and Immunity. 14, 3, p. 170-178 9 p.

Research output: Contribution to journalArticle

Antibodies
Kidney
Nephritis
Glomerulonephritis
Autoantibodies
7 Citations (Scopus)

Novel S-Gal® analogs as 1H MRI reporters for in vivo detection of β-galactosidase

Gulaka, P. K., Yu, J. X., Liu, L., Mason, R. P. & Kodibagkar, V. D., Jul 2013, In : Magnetic Resonance Imaging. 31, 6, p. 1006-1011 6 p.

Research output: Contribution to journalArticle

Galactosidases
Magnetic resonance imaging
Tumors
Enzyme activity
Gene expression
34 Citations (Scopus)

Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent

Hadimani, M. B., MacDonough, M. T., Ghatak, A., Strecker, T. E., Lopez, R., Sriram, M., Nguyen, B. L., Hall, J. J., Kessler, R. J., Shirali, A. R., Liu, L., Garner, C. M., Pettit, G. R., Hamel, E., Chaplin, D. J., Mason, R. P., Trawick, M. L. & Pinney, K. G., Sep 27 2013, In : Journal of Natural Products. 76, 9, p. 1668-1678 11 p.

Research output: Contribution to journalArticle

Prodrugs
Blood Vessels
Salts
Phosphates
Phenol
2012
21 Citations (Scopus)
Doppler Ultrasonography
arsenic
blood vessels
ultrasonography
Blood Vessels
32 Citations (Scopus)

Dual 19F/ 1H MR gene reporter molecules for in vivo detection of β-galactosidase

Yu, J. X., Kodibagkar, V. D., Hallac, R. R., Liu, L. & Mason, R. P., Mar 21 2012, In : Bioconjugate Chemistry. 23, 3, p. 596-603 8 p.

Research output: Contribution to journalArticle

Galactosidases
Reporter Genes
Magnetic Resonance Spectroscopy
Genes
Nuclear magnetic resonance
9 Citations (Scopus)

Dual-modality, dual-functional nanoprobes for cellular and molecular imaging

Menon, J. U., Gulaka, P. K., McKay, M. A., Geethanath, S., Liu, L. & Kodibagkar, V. D., 2012, In : Theranostics. 2, 12, p. 1199-1207 9 p.

Research output: Contribution to journalArticle

Molecular Imaging
Magnetic Resonance Imaging
Oximetry
Lecithins
Optical Imaging
12 Citations (Scopus)

Murine lupus strains differentially model unique facets of human lupus serology

Li, L., Nukala, S., Du, Y., Han, J., Liu, K., Hutcheson, J., Pathak, S., Li, Q. & Mohan, C., May 2012, In : Clinical and Experimental Immunology. 168, 2, p. 178-185 8 p.

Research output: Contribution to journalArticle

Serology
Autoantibodies
Immunoglobulin G
Systemic Lupus Erythematosus
Immunoglobulin M
9 Citations (Scopus)

Novel Fe 3+-Based 1H MRI β-galactosidase reporter molecules

Yu, J. X., Gulaka, P. K., Liu, L., Kodibagkar, V. D. & Mason, R. P., May 2012, In : ChemPlusChem. 77, 5, p. 370-378 9 p.

Research output: Contribution to journalArticle

Galactosidases
Magnetic resonance imaging
Molecules
Enzyme activity
Magnetic resonance
7 Citations (Scopus)

Serial Non-Invasive Monitoring of Renal Disease Following Immune-Mediated Injury Using Near-Infrared Optical Imaging

Du, Y., An, S., Liu, L., Li, L., Zhou, X. J., Mason, R. P. & Mohan, C., Sep 26 2012, In : PLoS One. 7, 9, e43941.

Research output: Contribution to journalArticle

Optical Imaging
Immune System Diseases
kidney diseases
basement membrane
Glomerular Basement Membrane
22 Citations (Scopus)

Tubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenografts

Liu, L., Beck, H., Wang, X., Hsieh, H. P., Mason, R. P. & Liu, X., Aug 24 2012, In : PLoS One. 7, 8, e43314.

Research output: Contribution to journalArticle

Tubulin
tubulin
Heterografts
blood vessels
breast neoplasms
2011
75 Citations (Scopus)

A perspective on vascular disrupting agents that interact with tubulin: Preclinical tumor imaging and biological assessment

Mason, R. P., Zhao, D., Liu, L., Trawick, M. L. & Pinney, K. G., Apr 2011, In : Integrative Biology. 3, 4, p. 375-387 13 p.

Research output: Contribution to journalArticle

Tubulin
Blood Vessels
Tumors
Imaging techniques
Neoplasms
2010
48 Citations (Scopus)
Galactosidases
galactosidases
Heterografts
Human Activities
Transgenic Mice
33 Citations (Scopus)

S-Gal®, a novel1H MRI reporter for β-galactosidase

Cui, W., Liu, L., Kodibagkar, V. D. & Mason, R. P., Jul 2010, In : Magnetic Resonance in Medicine. 64, 1, p. 65-71 7 p.

Research output: Contribution to journalArticle

Galactosidases
Galactose
Enzymes
Ions
Neoplasms
2009
14 Citations (Scopus)

Cell encapsulation and oxygenation in nanoporous microcontainers

Gimi, B., Kwon, J., Liu, L., Su, Y., Nemani, K., Trivedi, K., Cui, Y., Vachha, B., Mason, R., Hu, W. & Lee, J. B., Dec 2009, In : Biomedical Microdevices. 11, 6, p. 1205-1212 8 p.

Research output: Contribution to journalArticle

Nanopores
Oxygenation
Encapsulation
Grafts
Cell engineering
143 Citations (Scopus)

Development of aliphatic biodegradable photoluminescent polymers

Yang, J., Zhang, Y., Gautam, S., Liu, L., Dey, J., Chen, W., Mason, R. P., Serrano, C. A., Schug, K. A. & Tang, L., Jun 23 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 25, p. 10086-10091 6 p.

Research output: Contribution to journalArticle

Polymers
Quantum Dots
Tissue Engineering
Fluorescent Dyes
Tissue Scaffolds
16 Citations (Scopus)
26 Citations (Scopus)

The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis

Li, Q. Z., Zhou, J., Yang, R., Yan, M., Ye, Q., Liu, K., Liu, S., Shao, X., Li, L., Zhou, X. J., Wakeland, E. K. & Mohan, C., 2009, In : Genes and Immunity. 10, 5, p. 503-508 6 p.

Research output: Contribution to journalArticle

Kallikreins
Glomerulonephritis
Antibodies
Genes
Lupus Nephritis
2008
28 Citations (Scopus)

A 19F-NMR approach using reporter molecule pairs to assess β-galactosidase in human xenograft tumors in vivo

Yu, J. X., Kodibagkar, V. D., Liu, L. & Mason, R. P., Aug 2008, In : NMR in Biomedicine. 21, 7, p. 704-712 9 p.

Research output: Contribution to journalArticle

Galactosidases
Heterografts
Tumors
Nuclear magnetic resonance
Molecules
12 Citations (Scopus)

Evaluation of red CdTe and near infrared CdHgTe quantum dots by fluorescent imaging

Zhang, J., Su, J., Liu, L., Huang, Y. & Mason, R. P., Mar 2008, In : Journal of Nanoscience and Nanotechnology. 8, 3, p. 1155-1159 5 p.

Research output: Contribution to journalArticle

Quantum Dots
Semiconductor quantum dots
Infrared radiation
Fluorescent Dyes
Imaging techniques
41 Citations (Scopus)

Exploring feasibility of multicolored CdTe quantum dots for in Vitro and in Vivo fluorescent imaging

Su, J., Zhang, J., Liu, L., Huang, Y. & Mason, R. P., Mar 2008, In : Journal of Nanoscience and Nanotechnology. 8, 3, p. 1174-1177 4 p.

Research output: Contribution to journalArticle

Quantum Dots
Semiconductor quantum dots
Optical Imaging
Fluorescence
Imaging techniques
39 Citations (Scopus)

In vitro and in vivo assessment of CdTe and CdHgTe toxicity and clearance

Liu, L., Zhang, J., Su, X. & Mason, R. P., Dec 2008, In : Journal of Biomedical Nanotechnology. 4, 4, p. 524-528 5 p.

Research output: Contribution to journalArticle

Semiconductors
Toxicity
Semiconductor materials
Prostatic Neoplasms
Breast Neoplasms
2007
49 Citations (Scopus)
Galactosidases
Lac Operon
prostatic neoplasms
enzymatic hydrolysis
Galactose
2006
60 Citations (Scopus)

Imaging β-galactosidase activity using 19F chemical shift imaging of LacZ gene-reporter molecule 2-fluoro-4-nitrophenol-β-d-galactopyranoside

Kodibagkar, V. D., Yu, J., Liu, L., Hetherington, H. P. & Mason, R. P., Sep 2006, In : Magnetic Resonance Imaging. 24, 7, p. 959-962 4 p.

Research output: Contribution to journalArticle

Galactosidases
Lac Operon
Chemical shift
Galactose
genes
6 Citations (Scopus)

Phosphorylation of IκB-β is necessary for neuronal survival

Liu, L. & D'Mello, S. R., Jan 20 2006, In : Journal of Biological Chemistry. 281, 3, p. 1506-1515 10 p.

Research output: Contribution to journalArticle

Phosphorylation
Apoptosis
Neurons
Potassium
Consensus Sequence
39 Citations (Scopus)
Galactosidases
Galactose
Reporter Genes
Gene expression
Genes
2005
345 Citations (Scopus)

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

Zhu, Y., Guignard, F., Zhao, D., Liu, L., Burns, D. K., Mason, R. P., Messing, A. & Parada, L. F., Aug 2005, In : Cancer Cell. 8, 2, p. 119-130 12 p.

Research output: Contribution to journalArticle

Astrocytoma
Tumor Suppressor Genes
Neoplasms
Multipotent Stem Cells
Penetrance