• 11710 Citations
  • 26 h-Index
20042019
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Fingerprint Dive into the research topics where Lijun Sun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Antiviral Agents Medicine & Life Sciences
Innate Immunity Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences
GMP synthase (glutamine-hydrolyzing) Medicine & Life Sciences
Polyubiquitin Medicine & Life Sciences
Interferon Type I Medicine & Life Sciences
DNA Medicine & Life Sciences

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Research Output 2004 2019

  • 11710 Citations
  • 26 h-Index
  • 29 Article
  • 2 Review article
2 Citations (Scopus)

cGAS activation causes lupus-like autoimmune disorders in a TREX1 mutant mouse model

Xiao, N., Wei, J., Xu, S., Du, H., Huang, M., Zhang, S., Ye, W., Sun, L. & Chen, Q., Jun 1 2019, In : Journal of Autoimmunity. 100, p. 84-94 11 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Genes
Autoimmune Diseases
Exodeoxyribonucleases
Inflammation
19 Citations (Scopus)

Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids

Tan, X., Sun, L., Chen, J. & Chen, Z. J., Sep 8 2018, In : Annual Review of Microbiology. 72, p. 447-478 32 p.

Research output: Contribution to journalReview article

Pattern Recognition Receptors
Nucleic Acids
Infection
RNA
Interferon Type I
81 Citations (Scopus)

cGAS is essential for the antitumor effect of immune checkpoint blockade

Wang, H., Hu, S., Chen, X., Shi, H., Chen, C., Sun, L. & Chen, Z. J., Feb 14 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 7, p. 1637-1642 6 p.

Research output: Contribution to journalArticle

Adenosine Monophosphate
Cross-Priming
Interferon Type I
Experimental Melanomas
Antibodies
318 Citations (Scopus)

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing

Chen, Q., Sun, L. & Chen, Z. J., Sep 20 2016, In : Nature Immunology. 17, 10, p. 1142-1149 8 p.

Research output: Contribution to journalReview article

DNA
GMP synthase (glutamine-hydrolyzing)
Second Messenger Systems
Innate Immunity
Nucleic Acids
106 Citations (Scopus)

The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop

Zhang, X., Wu, J., Du, F., Xu, H., Sun, L., Chen, Z., Brautigam, C. A., Zhang, X. & Chen, Z., Feb 13 2014, In : Cell Reports. 6, 3, p. 421-430 10 p.

Research output: Contribution to journalArticle

Chemical activation
Switches
DNA
Sensors
GMP synthase (glutamine-hydrolyzing)