• 13575 Citations
  • 59 h-Index
19962020

Research output per year

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Research Output

2020

FRA1 contributes to MEK-ERK pathway-dependent PD-L1 upregulation by KRAS mutation in premalignant human bronchial epithelial cells

Lee, M. H., Yanagawa, J., Tran, L., Walser, T. C., Bisht, B., Fung, E., Park, S. J., Zeng, G., Krysan, K., Wallace, W. D., Paul, M. K., Girard, L., Gao, B., Minna, J. D., Dubinett, S. M. & Lee, J. M., Jan 1 2020, In : American Journal of Translational Research. 12, 2, p. 409-427 19 p.

Research output: Contribution to journalArticle

SLC43A3 is a biomarker of sensitivity to the telomeric DNA damage mediator 6-thio-2′-deoxyguanosine

Mender, I., Batten, K., Peyton, M., Vemula, A., Cornelius, C., Girard, L., Gao, B., Minna, J. D. & Shay, J. W., Mar 1 2020, In : Cancer research. 80, 5, p. 929-936 8 p.

Research output: Contribution to journalArticle

Stromal Hedgehog pathway activation by IHH suppresses lung adenocarcinoma growth and metastasis by limiting reactive oxygen species

Kasiri, S., Chen, B., Wilson, A. N., Reczek, A., Mazambani, S., Gadhvi, J., Noel, E., Marriam, U., Mino, B., Lu, W., Girard, L., Solis, L. M., Luby-Phelps, K., Bishop, J., Kim, J. W. & Kim, J., Apr 16 2020, In : Oncogene. 39, 16, p. 3258-3275 18 p.

Research output: Contribution to journalArticle

Open Access
2019

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access

Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer (Oncogene, (2019), 38, 14, (2551-2564), 10.1038/s41388-018-0588-2)

Cai, L., Lin, S. Y., Girard, L., Zhou, Y., Yang, L., Ci, B., Zhou, Q., Luo, D., Yao, B., Tang, H., Allen, J., Huffman, K., Gazdar, A. F., Heymach, J., Wistuba, I., Xiao, G., Minna, J. & Xie, Y., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalComment/debate

Inhibition of thioredoxin/thioredoxin reductase induces synthetic lethality in lung cancers with compromised glutathione homeostasis

Yan, X., Zhang, X., Wang, L., Zhang, R., Pu, X., Wu, S., Li, L., Tong, P., Wang, J., Meng, Q. H., Jensen, V. B., Girard, L., Minna, J. D., Roth, J. A., Swisher, S. G., Heymach, J. V. & Fang, B., Jan 1 2019, In : Cancer Research. 79, 1, p. 125-132 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

LCE: an open web portal to explore gene expression and clinical associations in lung cancer

Cai, L., Lin, S. Y., Girard, L., Zhou, Y., Yang, L., Ci, B., Zhou, Q., Luo, D., Yao, B., Tang, H., Allen, J., Huffman, K., Gazdar, A. F., Heymach, J., Wistuba, I., Xiao, G., Minna, J. D. & Xie, Y., Apr 4 2019, In : Oncogene. 38, 14, p. 2551-2564 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells

Chen, P. H., Cai, L., Huffman, K., Yang, C., Kim, J., Faubert, B., Boroughs, L., Ko, B., Sudderth, J., McMillan, E. A., Girard, L., Chen, D., Peyton, M., Shields, M. D., Yao, B., Shames, D. S., Kim, H. S., Timmons, B., Sekine, I., Britt, R. & 8 others, Weber, S., Byers, L. A., Heymach, J. V., Chen, J., White, M. A., Minna, J. D., Xiao, G. & DeBerardinis, R. J., Dec 5 2019, In : Molecular cell. 76, 5, p. 838-851.e5

Research output: Contribution to journalArticle

5 Scopus citations

Systematic analysis of gene expression in lung adenocarcinoma and squamous cell carcinoma with a case study of FAM83A and FAM83B

Cai, L., Luo, D., Yao, B., Yang, D. M., Lin, S., Girard, L., Deberardinis, R. J., Minna, J. D., Xie, Y. & Xiao, G., Jun 1 2019, In : Cancers. 11, 6, 886.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Unbiased peptoid combinatorial cell screen identifies plectin protein as a potential biomarker for lung cancer stem cells

Raymond, A. C., Gao, B., Girard, L., Minna, J. D. & Gomika Udugamasooriya, D., Dec 1 2019, In : Scientific reports. 9, 1, 14954.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

A quantitative method for assessing smoke associated molecular damage in lung cancers

Song, K., Bi, J. H., Qiu, Z. W., Felizardo, R., Girard, L., Minna, J. D. & Gazdar, A. F., Jan 1 2018, In : Translational Lung Cancer Research. 7, 4, p. 439-449 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

McMillan, E. A., Ryu, M. J., Diep, C. H., Mendiratta, S., Clemenceau, J. R., Vaden, R. M., Kim, J. H., Motoyaji, T., Covington, K. R., Peyton, M., Huffman, K., Wu, X., Girard, L., Sung, Y., Chen, P. H., Mallipeddi, P. L., Lee, J. Y., Hanson, J., Voruganti, S., Yu, Y. & 20 others, Park, S., Sudderth, J., DeSevo, C., Muzny, D. M., Doddapaneni, H. V., Gazdar, A., Gibbs, R. A., Hwang, T. H., Heymach, J. V., Wistuba, I., Coombes, K. R., Williams, N. S., Wheeler, D. A., MacMillan, J. B., Deberardinis, R. J., Roth, M. G., Posner, B. A., Minna, J. D., Kim, H. S. & White, M. A., May 3 2018, In : Cell. 173, 4, p. 864-878.e29

Research output: Contribution to journalArticle

20 Scopus citations

Concomitant targeting of the mTOR/MAPK pathways: Novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer

Ruder, D., Papadimitrakopoulou, V., Shien, K., Behrens, C., Kalhor, N., Chen, H., Shen, L., Jack Lee, J., Hong, W. K., Tang, X., Girard, L., Minna, J. D., Diao, L., Wang, J., Mino, B., Villalobos, P., Rodriguez-Canales, J., Hanson, N. E., Sun, J., Miller, V. & 6 others, Greenbowe, J., Frampton, G., Herbst, R. S., Baladandayuthapani, V., Wistuba, I. I. & Izzo, J. G., Sep 1 2018, In : Oncotarget. 9, 74, p. 33995-34008 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

eIF2β, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer

Tanaka, I., Sato, M., Kato, T., Goto, D., Kakumu, T., Miyazawa, A., Yogo, N., Hase, T., Morise, M., Sekido, Y., Girard, L., Minna, J. D., Byers, L. A., Heymach, J. V., Coombes, K. R., Kondo, M. & Hasegawa, Y., Jan 1 2018, (Accepted/In press) In : Cancer Science.

Research output: Contribution to journalArticle

3 Scopus citations

Kub5-HeraRPRD1B Deficiency Promotes "BRCAness" and Vulnerability to PARP Inhibition in BRCA-proficient Breast Cancers

Motea, E. A., Fattah, F. J., Xiao, L., Girard, L., Rommel, A., Morales, J. C., Patidar, P., Zhou, Y., Porter, A., Xie, Y., Minna, J. D. & Boothman, D. A., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6459-6470 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes

Zhang, W., Girard, L., Zhang, Y. A., Haruki, T., Papari-Zareei, M., Stastny, V., Ghayee, H. K., Pacak, K., Oliver, T. G., Minna, J. D. & Gazdar, A. F., Feb 1 2018, In : Translational Lung Cancer Research. 7, 1, p. 32-49 18 p.

Research output: Contribution to journalArticle

19 Scopus citations

Telomerase-Mediated Strategy for Overcoming Non–Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance

Mender, I., LaRanger, R., Luitel, K., Peyton, M., Girard, L., Lai, T. P., Batten, K., Cornelius, C., Dalvi, M. P., Ramirez, M., Du, W., Wu, L. F., Altschuler, S. J., Brekken, R., Martinez, E. D., Minna, J. D., Wright, W. E. & Shay, J. W., Aug 1 2018, In : Neoplasia (United States). 20, 8, p. 826-837 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors

He, M., Liu, S., Gallolu Kankanamalage, S., Borromeo, M. D., Girard, L., Gazdar, A. F., Minna, J. D., Johnson, J. E. & Cobb, M. H., Apr 1 2018, In : Translational Oncology. 11, 2, p. 292-299 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

Updegraff, B. L., Zhou, X., Guo, Y., Padanad, M. S., Chen, P. H., Yang, C., Sudderth, J., Rodriguez-Tirado, C., Girard, L., Minna, J. D., Mishra, P., DeBerardinis, R. J. & O'Donnell-Mendell, K. A., Jan 1 2018, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

5 Scopus citations
2017

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & Deberardinis, R. J., Jun 1 2017, In : Nature. 546, 7656, p. 168-172 5 p.

Research output: Contribution to journalArticle

63 Scopus citations

GLI1 blockade potentiates the antitumor activity of PI3K antagonists in lung squamous cell carcinoma

Kasiri, S., Shao, C., Chen, B., Wilson, A. N., Yenerall, P., Timmons, B. C., Girard, L., Tian, H., Behrens, C., Wistuba, I. I., Gazdar, A. F. & Kim, J., Aug 15 2017, In : Cancer Research. 77, 16, p. 4448-4459 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Identification of proteasomal catalytic subunit PSMA6 as a therapeutic target for lung cancer

Kakumu, T., Sato, M., Goto, D., Kato, T., Yogo, N., Hase, T., Morise, M., Fukui, T., Yokoi, K., Sekido, Y., Girard, L., Minna, J. D., Byers, L. A., Heymach, J. V., Coombes, K. R., Kondo, M. & Hasegawa, Y., Apr 1 2017, In : Cancer Science. 108, 4, p. 732-743 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

JAK1/STAT3 activation through a proinflammatory cytokine pathway leads to resistance to molecularly targeted therapy in non–small cell lung cancer

Shien, K., Papadimitrakopoulou, V. A., Ruder, D., Behrens, C., Shen, L., Kalhor, N., Song, J., Lee, J. J., Wang, J., Tang, X., Herbst, R. S., Toyooka, S., Girard, L., Minna, J. D., Kurie, J. M., Wistuba, I. I. & Izzo, J. G., Oct 2017, In : Molecular Cancer Therapeutics. 16, 10, p. 2234-2245 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions

Gao, B., Huang, C., Kernstine, K., Pelekanou, V., Kluger, Y., Jiang, T., Peters-Hall, J. R., Coquelin, M., Girard, L., Zhang, W., Huffman, K., Oliver, D., Kinose, F., Haura, E., Teer, J. K., Rix, U., Le, A. T., Aisner, D. L., Varella-Garcia, M., Doebele, R. C. & 10 others, Covington, K. R., Hampton, O. A., Doddapaneni, H. V., Jayaseelan, J. C., Hu, J., Wheeler, D. A., Shay, J. W., Rimm, D. L., Gazdar, A. & Minna, J. D., Jan 1 2017, In : Oncotarget. 8, 7, p. 11114-11126 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

PROTOCADHERIN 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis

Zhou, X., Updegraff, B. L., Guo, Y., Peyton, M., Girard, L., Larsen, J. E., Xie, X-J., Zhou, Y., Hwang, T. H., Xie, Y., Rodriguez-Canales, J., Villalobos, P., Behrens, C., Wistuba, I. I., Minna, J. D. & O'Donnell-Mendell, K. A., Jan 1 2017, In : Cancer Research. 77, 1, p. 187-197 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer

Zhao, X., Huffman, K. E., Fujimoto, J., Canales, J. R., Girard, L., Nie, G., Heymach, J. V., Wistuba, I. I., Minna, J. D. & Yu, Y., Oct 1 2017, In : Journal of the American Society for Mass Spectrometry. 28, 10, p. 2078-2089 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

Tagal, V., Wei, S., Zhang, W., Brekken, R. A., Posner, B. A., Peyton, M., Girard, L., Hwang, T., Wheeler, D. A., Minna, J. D., White, M. A., Gazdar, A. F. & Roth, M. G., Jan 19 2017, In : Nature Communications. 8, 14098.

Research output: Contribution to journalArticle

27 Scopus citations

Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors

Dalvi, M. P., Wang, L., Zhong, R., Kollipara, R. K., Park, H., Bayo, J., Yenerall, P., Zhou, Y., Timmons, B. C., Rodriguez-Canales, J., Behrens, C., Mino, B., Villalobos, P., Parra, E. R., Suraokar, M., Pataer, A., Swisher, S. G., Kalhor, N., Bhanu, N. V., Garcia, B. A. & 9 others, Heymach, J. V., Coombes, K., Xie, Y., Girard, L., Gazdar, A. F., Kittler, R., Wistuba, I. I., Minna, J. D. & Martinez, E. D., May 23 2017, In : Cell Reports. 19, 8, p. 1669-1684 16 p.

Research output: Contribution to journalArticle

29 Scopus citations
2016

An expression signature as an aid to the histologic classification of non-small cell lung cancer

Girard, L., Rodriguez-Canales, J., Behrens, C., Thompson, D. M., Botros, I. W., Tang, H., Xie, Y., Rekhtman, N., Travis, W. D., Wistuba, I. I., Minna, J. D. & Gazdar, A. F., Oct 1 2016, In : Clinical Cancer Research. 22, 19, p. 4880-4889 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs

Borromeo, M. D., Savage, T. K., Kollipara, R. K., He, M., Augustyn, A., Osborne, J. K., Girard, L., Minna, J. D., Gazdar, A. F., Cobb, M. H. & Johnson, J. E., Aug 2 2016, In : Cell Reports. 16, 5, p. 1259-1272 14 p.

Research output: Contribution to journalArticle

85 Scopus citations

Epithelial-mesenchymal transition predicts polo-like kinase 1 inhibitor-mediated apoptosis in non-small cell lung cancer

Ferrarotto, R., Goonatilake, R., Yoo, S. Y., Tong, P., Giri, U., Peng, S., Minna, J., Girard, L., Wang, Y., Wang, L., Li, L., Diao, L., Peng, D. H., Gibbons, D. L., Glisson, B. S., Heymach, J. V., Wang, J., Byers, L. A. & Johnson, F. M., Apr 1 2016, In : Clinical Cancer Research. 22, 7, p. 1674-1686 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Identification of gene expression differences between lymphangiogenic and non-lymphangiogenic non-small cell lung cancer cell lines

Regan, E., Sibley, R. C., Cenik, B. K., Silva, A., Girard, L., Minna, J. D. & Dellinger, M. T., Mar 1 2016, In : PLoS One. 11, 3, e150963.

Research output: Contribution to journalArticle

7 Scopus citations

ITPKA gene body methylation regulates gene expression and serves as an early diagnostic marker in lung and other cancers

Wang, Y. W., Ma, X., Zhang, Y. A., Wang, M. J., Yatabe, Y., Lam, S., Girard, L., Chen, J. Y. & Gazdar, A. F., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 9, p. 1469-1481 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Selecting reliable mRNA expression measurements across platforms improves downstream analysis

Tong, P., Diao, L., Shen, L., Li, L., Heymach, J. V., Girard, L., Minna, J. D., Coombes, K. R., Byers, L. A. & Wang, J., 2016, In : Cancer Informatics. 15, p. 81-89 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

SHOX2 is a Potent Independent Biomarker to Predict Survival of WHO Grade II–III Diffuse Gliomas

Zhang, Y. A., Zhou, Y., Luo, X., Song, K., Ma, X., Sathe, A., Girard, L., Xiao, G. & Gazdar, A. F., Nov 1 2016, In : EBioMedicine. 13, p. 80-89 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Validation of SCT methylation as a hallmark biomarker for lung cancers

Zhang, Y. A., Ma, X., Sathe, A., Fujimoto, J., Wistuba, I. I., Lam, S., Yatabe, Y., Wang, Y. W., Stastny, V., Gao, B., Larsen, J. E., Girard, L., Liu, X., Song, K., Behrens, C., Kalhor, N., Xie, Y., Zhang, M. Q., Minna, J. D. & Gazdar, A. F., Mar 23 2016, In : Journal of Thoracic Oncology. 11, 3, p. 346-360 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

Larsen, J. E., Nathan, V., Osborne, J. K., Farrow, R. K., Deb, D., Sullivan, J. P., Dospoy, P. D., Augustyn, A., Hight, S. K., Sato, M., Girard, L., Behrens, C., Wistuba, I. I., Gazdar, A. F., Hayward, N. K. & Minna, J. D., Sep 1 2016, In : Journal of Clinical Investigation. 126, 9, p. 3219-3235 17 p.

Research output: Contribution to journalArticle

95 Scopus citations
2015

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

Skoulidis, F., Byers, L. A., Diao, L., Papadimitrakopoulou, V. A., Tong, P., Izzo, J., Behrens, C., Kadara, H., Parra, E. R., Canales, J. R., Zhang, J., Giri, U., Gudikote, J., Cortez, M. A., Yang, C., Fan, Y., Peyton, M., Girard, L., Coombes, K. R., Toniatti, C. & 17 others, Heffernan, T. P., Choi, M., Frampton, G. M., Miller, V., Weinstein, J. N., Herbst, R. S., Wong, K. K., Zhang, J., Sharma, P., Mills, G. B., Hong, W. K., Minna, J. D., Allison, J. P., Futrea, A., Wang, J., Wistuba, I. I. & Heymach, J. V., Aug 1 2015, In : Cancer discovery. 5, 8, p. 861-878 18 p.

Research output: Contribution to journalArticle

255 Scopus citations
5 Scopus citations

On comparing heterogeneity across biomarkers

Steininger, R. J., Rajaram, S., Girard, L., Minna, J. D., Wu, L. F. & Altschuler, S. J., Jun 1 2015, In : Cytometry Part A. 87, 6, p. 558-567 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Systematic siRNA screen unmasks NSCLC growth dependence by palmitoyltransferase DHHC5

Tian, H., Lu, J. Y., Shao, C., Huffman, K. E., Carstens, R. M., Larsen, J. E., Girard, L., Liu, H., Rodriguez-Canales, J., Frenkel, E. P., Wistuba, I. I., Minna, J. D. & Hofmann, S. L., Apr 1 2015, In : Molecular Cancer Research. 13, 4, p. 784-794 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2014

Aiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells

Li, X., Xu, Z., Du, W., Zhang, Z., Wei, Y., Wang, H., Zhu, Z., Qin, L., Wang, L., Niu, Q., Zhao, X., Girard, L., Gong, Y., Ma, Z., Sun, B., Yao, Z., Minna, J. D., Terada, L. S. & Liu, Z., May 12 2014, In : Cancer Cell. 25, 5, p. 575-589 15 p.

Research output: Contribution to journalArticle

38 Scopus citations

Analysis of TP53 mutation status in human cancer cell lines: A reassessment

Leroy, B., Girard, L., Hollestelle, A., Minna, J. D., Gazdar, A. F. & Soussi, T., Jun 2014, In : Human mutation. 35, 6, p. 756-765 10 p.

Research output: Contribution to journalReview article

62 Scopus citations

A reevaluation of CD22 expression in human lung cancer

Pop, L. M., Barman, S., Shao, C., Poe, J. C., Venturi, G. M., Shelton, J. M., Pop, I. V., Gerber, D. E., Girard, L., Liu, X. Y., Behrens, C., Rodriguez-Canales, J., Liu, H., Wistuba, I. I., Richardson, J. A., Minna, J. D., Tedder, T. F. & Vitetta, E. S., Jan 1 2014, In : Cancer research. 74, 1, p. 263-271 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

Augustyn, A., Borromeo, M., Wang, T., Fujimoto, J., Shao, C., Dospoy, P. D., Lee, V., Tan, C., Sullivan, J. P., Larsen, J. E., Girard, L., Behrens, C., Wistuba, I. I., Xie, Y., Cobb, M. H., Gazdar, A. F., Johnson, J. E. & Minna, J. D., Oct 14 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 41, p. 14788-14793 6 p.

Research output: Contribution to journalArticle

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

Augustyn, A., Borromeo, M., Wang, T., Fujimoto, J., Shao, C., Dospoy, P. D., Lee, V., Tan, C., Sullivan, J. P., Larsen, J. E., Girard, L., Behrens, C., Wistuba, I. I., Xie, Y., Cobb, M. H., Gazdar, A. F., Johnson, J. E., Minna, J. D. & Vogt, P. K., Oct 14 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 41, p. 14788-14793 6 p.

Research output: Contribution to journalArticle

Open Access
93 Scopus citations

A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets

Taguchi, A., Taylor, A. D., Rodriguez, J., Çeliktaş, M., Liu, H., Ma, X., Zhang, Q., Wong, C. H., Chin, A., Girard, L., Behrens, C., Lam, W. L., Lam, S., Minna, J. D., Wistuba, I. I., Gazdar, A. F. & Hanash, S. M., Sep 1 2014, In : Cancer research. 74, 17, p. 4694-4705 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells is associated with the STAT3 pathway

Shao, C., Sullivan, J. P., Girard, L., Augustyn, A., Yenerall, P., Rodriguez-Canales, J., Liu, H., Behrens, C., Shay, J. W., Wistuba, I. I. & Minna, J. D., Aug 1 2014, In : Clinical Cancer Research. 20, 15, p. 4154-4166 13 p.

Research output: Contribution to journalArticle

84 Scopus citations

Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition

Lin, S. H., Wang, J., Saintigny, P., Wu, C. C., Giri, U., Zhang, J., Menju, T., Diao, L., Byers, L., Weinstein, J. N., Coombes, K. R., Girard, L., Komaki, R., Wistuba, I. I., Date, H., Minna, J. D. & Heymach, J. V., 2014, In : BMC Genomics. 15, p. 1079 1 p.

Research output: Contribution to journalArticle

Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition

Lin, S. H., Wang, J., Saintigny, P., Wu, C. C., Giri, U., Zhang, J., Menju, T., Diao, L., Byers, L., Weinstein, J. N., Coombes, K. R., Girard, L., Komaki, R., Wistuba, I. I., Date, H., Minna, J. D. & Heymach, J. V., Dec 8 2014, In : BMC Genomics. 15, 1, 1079.

Research output: Contribution to journalArticle

29 Scopus citations