• 13575 Citations
  • 59 h-Index
19962020

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Article

Potential application of non-small cell lung cancer-associated autoantibodies to early cancer diagnosis

Yao, Y., Fan, Y., Wu, J., Wan, H., Wang, J., Lam, S., Lam, W. L., Girard, L., Gazdar, A. F., Wu, Z. & Zhou, Q., Jul 6 2012, In : Biochemical and Biophysical Research Communications. 423, 3, p. 613-619 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions

Sos, M. L., Michel, K., Zander, T., Weiss, J., Frommolt, P., Peifer, M., Li, D., Ullrich, R., Koker, M., Fischer, F., Shimamura, T., Rauh, D., Mermel, C., Fischer, S., Stückrath, I., Heynck, S., Beroukhim, R., Lin, W., Winckler, W., Shah, K. & 23 others, LaFramboise, T., Moriarty, W. F., Hanna, M., Tolosi, L., Rahnenführer, J., Verhaak, R., Chiang, D., Getz, G., Hellmich, M., Wolf, J., Girard, L., Peyton, M., Weir, B. A., Chen, T. H., Greulich, H., Barretina, J., Shapiro, G. I., Garraway, L. A., Gazdar, A. F., Minna, J. D., Meyerson, M., Wong, K. K. & Thomas, R. K., Jun 1 2009, In : Journal of Clinical Investigation. 119, 6, p. 1727-1740 14 p.

Research output: Contribution to journalArticle

201 Scopus citations

Probe mapping across multiple microarray platforms

Allen, J. D., Wang, S., Chen, M., Girard, L., Minna, J. D., Xie, Y. & Xiao, G., Sep 1 2012, In : Briefings in Bioinformatics. 13, 5, p. 547-554 8 p., bbr076.

Research output: Contribution to journalArticle

17 Scopus citations

Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1

Byers, L. A., Wang, J., Nilsson, M. B., Fujimoto, J., Saintigny, P., Yordy, J., Giri, U., Peyton, M., Fan, Y. H., Diao, L., Masrorpour, F., Shen, L., Liu, W., Duchemann, B., Tumula, P., Bhardwaj, V., Welsh, J., Weber, S., Glisson, B. S., Kalhor, N. & 8 others, Wistuba, I. I., Girard, L., Lippman, S. M., Mills, G. B., Coombes, K. R., Weinstein, J. N., Minna, J. D. & Heymach, J. V., Sep 1 2012, In : Cancer discovery. 2, 9, p. 798-811 14 p.

Research output: Contribution to journalArticle

236 Scopus citations

PROTOCADHERIN 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis

Zhou, X., Updegraff, B. L., Guo, Y., Peyton, M., Girard, L., Larsen, J. E., Xie, X-J., Zhou, Y., Hwang, T. H., Xie, Y., Rodriguez-Canales, J., Villalobos, P., Behrens, C., Wistuba, I. I., Minna, J. D. & O'Donnell-Mendell, K. A., Jan 1 2017, In : Cancer Research. 77, 1, p. 187-197 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of akt and EGFR

Sos, M. L., Koker, M., Weir, B. A., Heynck, S., Rabinovsky, R., Zander, T., Seeger, J. M., Weiss, J., Fischer, F., Frommolt, P., Michel, K., Peifer, M., Mermel, C., Girard, L., Peyton, M., Gazdar, A. F., Minna, J. D., Garraway, L. A., Kashkar, H., Pao, W. & 2 others, Meyerson, M. & Thomas, R. K., Apr 15 2009, In : Cancer research. 69, 8, p. 3256-3261 6 p.

Research output: Contribution to journalArticle

372 Scopus citations

Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer

Zhao, X., Huffman, K. E., Fujimoto, J., Canales, J. R., Girard, L., Nie, G., Heymach, J. V., Wistuba, I. I., Minna, J. D. & Yu, Y., Oct 1 2017, In : Journal of the American Society for Mass Spectrometry. 28, 10, p. 2078-2089 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer

Delgado, O., Batten, K. G., Richardson, J. A., Xie, X. J., Gazdar, A. F., Kaisani, A. A., Girard, L., Behrens, C., Suraokar, M., Fasciani, G., Wright, W. E., Story, M. D., Wistuba, I. I., Minna, J. D. & Shay, J. W., Jan 1 2014, In : Clinical Cancer Research. 20, 6, p. 1610-1622 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells

Zaganjor, E., Osborne, J. K., Weil, L. M., Diaz-Martinez, L. A., Gonzales, J. X., Singel, S. M., Larsen, J. E., Girard, L., Minna, J. D. & Cobb, M. H., Nov 20 2014, In : Oncogene. 33, 47, p. 5457-5466 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer

Jeong, Y., Xie, Y., Lee, W., Bookout, A. L., Girard, L., Raso, G., Behrens, C., Wistuba, I. I., Gadzar, A. F., Minna, J. D. & Mangelsdorf, D. J., Aug 1 2012, In : Molecular Endocrinology. 26, 8, p. 1443-1454 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines

Witta, S. E., Gemmill, R. M., Hirsch, F. R., Coldren, C. D., Hedman, K., Ravdel, L., Helfrich, B., Dziadziuszko, R., Chan, D. C., Sugita, M., Chan, Z., Baron, A., Franklin, W., Drabkin, H. A., Girard, L., Gazdar, A. F., Minna, J. D. & Bunn, P. A., Jan 15 2006, In : Cancer Research. 66, 2, p. 944-950 7 p.

Research output: Contribution to journalArticle

396 Scopus citations

Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients

Xie, Y., Xiao, G., Coombes, K. R., Behrens, C., Solis, L. M., Raso, G., Girard, L., Erickson, H. S., Roth, J., Heymach, J. V., Moran, C., Danenberg, K., Minna, J. D. & Wistuba, I. I., Sep 1 2011, In : Clinical Cancer Research. 17, 17, p. 5705-5714 10 p.

Research output: Contribution to journalArticle

83 Scopus citations

Seizure 6-like (SEZ6L) gene and risk for lung cancer

Gorlov, I. P., Meyer, P., Liloglou, T., Myles, J., Boettger, M. B., Cassidy, A., Girard, L., Minna, J. D., Fischer, R., Duffy, S., Spitz, M. R., Haeussinger, K., Kammerer, S., Cantor, C., Dierkesmann, R., Field, J. K. & Amos, C. I., Sep 1 2007, In : Cancer research. 67, 17, p. 8406-8411 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Selecting reliable mRNA expression measurements across platforms improves downstream analysis

Tong, P., Diao, L., Shen, L., Li, L., Heymach, J. V., Girard, L., Minna, J. D., Coombes, K. R., Byers, L. A. & Wang, J., 2016, In : Cancer Informatics. 15, p. 81-89 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sex determining region Y-box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung

Yuan, P., Kadara, H., Behrens, C., Tang, X., Woods, D., Solis, L. M., Huang, J., Spinola, M., Dong, W., Yin, G., Fujimoto, J., Kim, E., Xie, Y., Girard, L., Moran, C., Hong, W. K., Minna, J. D. & Wistuba, I. I., Feb 9 2010, In : PloS one. 5, 2, e9112.

Research output: Contribution to journalArticle

98 Scopus citations

SHOX2 is a Potent Independent Biomarker to Predict Survival of WHO Grade II–III Diffuse Gliomas

Zhang, Y. A., Zhou, Y., Luo, X., Song, K., Ma, X., Sathe, A., Girard, L., Xiao, G. & Gazdar, A. F., Nov 1 2016, In : EBioMedicine. 13, p. 80-89 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

SLC43A3 is a biomarker of sensitivity to the telomeric DNA damage mediator 6-thio-2′-deoxyguanosine

Mender, I., Batten, K., Peyton, M., Vemula, A., Cornelius, C., Girard, L., Gao, B., Minna, J. D. & Shay, J. W., Mar 1 2020, In : Cancer research. 80, 5, p. 929-936 8 p.

Research output: Contribution to journalArticle

SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner

Greer, R. M., Peyton, M., Larsen, J. E., Girard, L., Xie, Y., Gazdar, A. F., Harran, P., Wang, L., Brekken, R. A., Wang, X. & Minna, J. D., Dec 15 2011, In : Cancer Research. 71, 24, p. 7640-7648 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes

Zhang, W., Girard, L., Zhang, Y. A., Haruki, T., Papari-Zareei, M., Stastny, V., Ghayee, H. K., Pacak, K., Oliver, T. G., Minna, J. D. & Gazdar, A. F., Feb 1 2018, In : Translational Lung Cancer Research. 7, 1, p. 32-49 18 p.

Research output: Contribution to journalArticle

19 Scopus citations

SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

Tagal, V., Wei, S., Zhang, W., Brekken, R. A., Posner, B. A., Peyton, M., Girard, L., Hwang, T., Wheeler, D. A., Minna, J. D., White, M. A., Gazdar, A. F. & Roth, M. G., Jan 19 2017, In : Nature Communications. 8, 14098.

Research output: Contribution to journalArticle

27 Scopus citations

STAT3 mediates resistance to MEK inhibitor through microRNA miR-17

Dai, B., Meng, J., Peyton, M., Girard, L., Bornmann, W. G., Ji, L., Minna, J. D., Fang, B. & Roth, J. A., May 15 2011, In : Cancer research. 71, 10, p. 3658-3668 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation

Cai, D., Shames, D. S., Raso, M. G., Xie, Y., Kim, Y. H., Pollack, J. R., Girard, L., Sullivan, J. P., Gao, B., Peyton, M., Nanjundan, M., Byers, L., Heymach, J., Mills, G., Gazdar, A. F., Wistuba, I., Kodadek, T. & Minna, J. D., Aug 15 2010, In : Cancer research. 70, 16, p. 6477-6485 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Stromal Hedgehog pathway activation by IHH suppresses lung adenocarcinoma growth and metastasis by limiting reactive oxygen species

Kasiri, S., Chen, B., Wilson, A. N., Reczek, A., Mazambani, S., Gadhvi, J., Noel, E., Marriam, U., Mino, B., Lu, W., Girard, L., Solis, L. M., Luby-Phelps, K., Bishop, J., Kim, J. W. & Kim, J., Apr 16 2020, In : Oncogene. 39, 16, p. 3258-3275 18 p.

Research output: Contribution to journalArticle

Open Access

Synthetic lethal screen identification of chemosensitizer loci in cancer cells

Whitehurst, A. W., Bodemann, B. O., Cardenas, J., Ferguson, D., Girard, L., Peyton, M., Minna, J. D., Michnoff, C., Hao, W., Roth, M. G., Xie, X. J. & White, M. A., Apr 12 2007, In : Nature. 446, 7137, p. 815-819 5 p.

Research output: Contribution to journalArticle

378 Scopus citations

Systematic analysis of gene expression in lung adenocarcinoma and squamous cell carcinoma with a case study of FAM83A and FAM83B

Cai, L., Luo, D., Yao, B., Yang, D. M., Lin, S., Girard, L., Deberardinis, R. J., Minna, J. D., Xie, Y. & Xiao, G., Jun 1 2019, In : Cancers. 11, 6, 886.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Systematic siRNA screen unmasks NSCLC growth dependence by palmitoyltransferase DHHC5

Tian, H., Lu, J. Y., Shao, C., Huffman, K. E., Carstens, R. M., Larsen, J. E., Girard, L., Liu, H., Rodriguez-Canales, J., Frenkel, E. P., Wistuba, I. I., Minna, J. D. & Hofmann, S. L., Apr 1 2015, In : Molecular Cancer Research. 13, 4, p. 784-794 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer

Zhou, B. B. S., Peyton, M., He, B., Liu, C., Girard, L., Caudler, E., Lo, Y., Baribaud, F., Mikami, I., Reguart, N., Yang, G., Li, Y., Yao, W., Vaddi, K., Gazdar, A. F., Friedman, S. M., Jablons, D. M., Newton, R. C., Fridman, J. S., Minna, J. D. & 1 others, Scherle, P. A., Jul 1 2006, In : Cancer Cell. 10, 1, p. 39-50 12 p.

Research output: Contribution to journalArticle

290 Scopus citations

Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors

Dalvi, M. P., Wang, L., Zhong, R., Kollipara, R. K., Park, H., Bayo, J., Yenerall, P., Zhou, Y., Timmons, B. C., Rodriguez-Canales, J., Behrens, C., Mino, B., Villalobos, P., Parra, E. R., Suraokar, M., Pataer, A., Swisher, S. G., Kalhor, N., Bhanu, N. V., Garcia, B. A. & 9 others, Heymach, J. V., Coombes, K., Xie, Y., Girard, L., Gazdar, A. F., Kittler, R., Wistuba, I. I., Minna, J. D. & Martinez, E. D., May 23 2017, In : Cell Reports. 19, 8, p. 1669-1684 16 p.

Research output: Contribution to journalArticle

29 Scopus citations

Telomerase-Mediated Strategy for Overcoming Non–Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance

Mender, I., LaRanger, R., Luitel, K., Peyton, M., Girard, L., Lai, T. P., Batten, K., Cornelius, C., Dalvi, M. P., Ramirez, M., Du, W., Wu, L. F., Altschuler, S. J., Brekken, R., Martinez, E. D., Minna, J. D., Wright, W. E. & Shay, J. W., Aug 1 2018, In : Neoplasia (United States). 20, 8, p. 826-837 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells

Ueda, K., Kawashima, H., Ohtani, S., Deng, W. G., Ravoori, M., Bankson, J., Gao, B., Girard, L., Minna, J. D., Roth, J. A., Kundra, V. & Ji, L., Oct 1 2006, In : Cancer research. 66, 19, p. 9682-9690 9 p.

Research output: Contribution to journalArticle

56 Scopus citations
500 Scopus citations

The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors

He, M., Liu, S., Gallolu Kankanamalage, S., Borromeo, M. D., Girard, L., Gazdar, A. F., Minna, J. D., Johnson, J. E. & Cobb, M. H., Apr 1 2018, In : Translational Oncology. 11, 2, p. 292-299 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA

Rabellino, A., Carter, B., Konstantinidou, G., Wu, S. Y., Rimessi, A., Byers, L. A., Heymach, J. V., Girard, L., Chiang, C. M., Teruya-Feldstein, J. & Scaglioni, P. P., May 1 2012, In : Cancer research. 72, 9, p. 2275-2284 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival

Yoshida, K., Sato, M., Hase, T., Elshazley, M., Yamashita, R., Usami, N., Taniguchi, T., Yokoi, K., Nakamura, S., Kondo, M., Girard, L., Minna, J. D. & Hasegawa, Y., Feb 1 2013, In : Cancer Science. 104, 2, p. 171-177 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

Updegraff, B. L., Zhou, X., Guo, Y., Padanad, M. S., Chen, P. H., Yang, C., Sudderth, J., Rodriguez-Tirado, C., Girard, L., Minna, J. D., Mishra, P., DeBerardinis, R. J. & O'Donnell-Mendell, K. A., Jan 1 2018, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

5 Scopus citations

Tumor antigen acrosin binding protein normalizes mitotic spindle function to promote cancer cell proliferation

Whitehurst, A. W., Xie, Y., Purinton, S. C., Cappell, K. M., Swanik, J. T., Larson, B., Girard, L., Schorge, J. O. & White, M. A., Oct 1 2010, In : Cancer research. 70, 19, p. 7652-7661 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Two distinct Notch1 mutant alleles are involved in the induction of T- cell leukemia in c-myc transgenic mice

Hoemann, C. D., Beaulieu, N., Girard, L., Rebai, N. & Jolicoeur, P., Jun 1 2000, In : Molecular and cellular biology. 20, 11, p. 3831-3842 12 p.

Research output: Contribution to journalArticle

75 Scopus citations

Unbiased peptoid combinatorial cell screen identifies plectin protein as a potential biomarker for lung cancer stem cells

Raymond, A. C., Gao, B., Girard, L., Minna, J. D. & Gomika Udugamasooriya, D., Dec 1 2019, In : Scientific reports. 9, 1, 14954.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Validation of SCT methylation as a hallmark biomarker for lung cancers

Zhang, Y. A., Ma, X., Sathe, A., Fujimoto, J., Wistuba, I. I., Lam, S., Yatabe, Y., Wang, Y. W., Stastny, V., Gao, B., Larsen, J. E., Girard, L., Liu, X., Song, K., Behrens, C., Kalhor, N., Xie, Y., Zhang, M. Q., Minna, J. D. & Gazdar, A. F., Mar 23 2016, In : Journal of Thoracic Oncology. 11, 3, p. 346-360 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy

Riquelme, E., Suraokar, M., Behrens, C., Lin, H. Y., Girard, L., Nilsson, M. B., Simon, G., Wang, J., Coombes, K. R., Lee, J. J., Hong, W. K., Heymach, J., Minna, J. D. & Wistuba, I. I., Jul 15 2014, In : Clinical Cancer Research. 20, 14, p. 3849-3861 13 p.

Research output: Contribution to journalArticle

28 Scopus citations

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

Larsen, J. E., Nathan, V., Osborne, J. K., Farrow, R. K., Deb, D., Sullivan, J. P., Dospoy, P. D., Augustyn, A., Hight, S. K., Sato, M., Girard, L., Behrens, C., Wistuba, I. I., Gazdar, A. F., Hayward, N. K. & Minna, J. D., Sep 1 2016, In : Journal of Clinical Investigation. 126, 9, p. 3219-3235 17 p.

Research output: Contribution to journalArticle

95 Scopus citations