• 9800 Citations
  • 57 h-Index
1989 …2019
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Research Output 1989 2019

  • 9800 Citations
  • 57 h-Index
  • 118 Article
  • 6 Review article
  • 3 Comment/debate
  • 3 Short survey
2019

Enhancing cardiac glycolysis causes an increase in PDK4 content in response to short-term high-fat diet

Newhardt, M. F., Batushansky, LA., Matsuzaki, S., Young, Z. T., West, M., Cer Chin, N., Szweda, L. I., Kinter, M. & Humphries, K. M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 45, p. 16831-16845 15 p.

Research output: Contribution to journalArticle

High Fat Diet
Glycolysis
Nutrition
Fatty Acids
Fats
25 Citations (Scopus)

Evidence for hormonal control of heart regenerative capacity during endothermy acquisition

Hirose, K., Payumo, A. Y., Cutie, S., Hoang, A., Zhang, H., Guyot, R., Lunn, D., Bigley, R. B., Yu, H., Wang, J., Smith, M., Gillett, E., Muroy, S. E., Schmid, T., Wilson, E., Field, K. A., Reeder, D. A. M., Maden, M., Yartsev, M. M., Wolfgang, M. J. & 8 others, Grützner, F., Scanlan, T. S., Szweda, L. I., Buffenstein, R., Hu, G., Flamant, F., Olgin, J. E. & Huang, G. N., Jan 1 2019, In : Science. 364, 6436, p. 184-188 5 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Cardiac Myocytes
Zebrafish
Phylogeny
Cell Cycle Checkpoints
4 Citations (Scopus)

High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice

Peri-Okonny, P., Baskin, K. K., Iwamoto, G., Mitchell, J. H., Smith, S. A., Kim, H. K., Szweda, L. I., Bassel-Duby, R., Fujikawa, T., Castorena, C. M., Richardson, J., Shelton, J. M., Ayers, C., Berry, J. D., Malladi, V. S., Hu, M. C., Moe, O. W., Scherer, P. E. & Vongpatanasin, W., Mar 12 2019, In : Circulation. 139, 11, p. 1422-1434 13 p.

Research output: Contribution to journalArticle

Fatty Acids
Phosphates
Diet
Skeletal Muscle Fibers
Serum
2018
4 Citations (Scopus)

Coenzyme A–mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice

Schafer, C., Young, Z. T., Makarewich, C. A., Elnwasany, A., Kinter, C., Kinter, M. & Szweda, L. I., Jan 1 2018, In : Journal of Biological Chemistry. 293, 18, p. 6915-6924 10 p.

Research output: Contribution to journalArticle

Coenzymes
Pyruvic Acid
Fats
Nutrition
Degradation
26 Citations (Scopus)

Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes

Logan, S., Pharaoh, G. A., Marlin, M. C., Masser, D. R., Matsuzaki, S., Wronowski, B., Yeganeh, A., Parks, E. E., Premkumar, P., Farley, J. A., Owen, D. B., Humphries, K. M., Kinter, M., Freeman, W. M., Szweda, L. I., Van Remmen, H. & Sonntag, W. E., Jan 1 2018, (Accepted/In press) In : Molecular Metabolism.

Research output: Contribution to journalArticle

Somatomedin Receptors
Short-Term Memory
Amyloid
Astrocytes
Somatomedins
12 Citations (Scopus)

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation

Makarewich, C. A., Baskin, K. K., Munir, A. Z., Bezprozvannaya, S., Sharma, G., Khemtong, C., Shah, A. M., McAnally, J. R., Malloy, C. R., Szweda, L. I., Bassel-Duby, R. & Olson, E. N., Jun 26 2018, In : Cell Reports. 23, 13, p. 3701-3709 9 p.

Research output: Contribution to journalArticle

Mitochondrial Membranes
Fatty Acids
RNA
Muscles
Oxidation
11 Citations (Scopus)

Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass

Ahn, B., Pharaoh, G., Premkumar, P., Huseman, K., Ranjit, R., Kinter, M., Szweda, L., Kiss, T., Fulop, G., Tarantini, S., Csiszar, A., Ungvari, Z. & Van Remmen, H., Jul 1 2018, In : Redox Biology. 17, p. 47-58 12 p.

Research output: Contribution to journalArticle

NF-E2-Related Factor 2
Mitochondria
Oxidative stress
Muscle
Reactive Oxygen Species
2017
18 Citations (Scopus)

Consuming a Ketogenic Diet while Receiving Radiation and Chemotherapy for Locally Advanced Lung Cancer and Pancreatic Cancer: The University of Iowa Experience of Two Phase 1 Clinical Trials

Zahra, A., Fath, M. A., Opat, E., Mapuskar, K. A., Bhatia, S. K., Ma, D. C., Iii, S. N. R., Snyders, T. P., Chenard, C. A., Eichenberger-Gilmore, J. M., Bodeker, K. L., Ahmann, L., Smith, B. J., Vollstedt, S. A., Brown, H. A., Hejleh, T. A., Clamon, G. H., Berg, D. J., Szweda, L. I., Spitz, D. R. & 2 others, Buatti, J. M. & Allen, B. G., Jun 1 2017, In : Radiation Research. 187, 6, p. 743-754 12 p.

Research output: Contribution to journalArticle

Ketogenic Diet
diets
Clinical Trials, Phase I
chemotherapy
Pancreatic Neoplasms
2 Citations (Scopus)

Glucose availability controls adipogenesis in mouse 3T3-L1 adipocytes via up-regulation of nicotinamide metabolism

Jackson, R. M., Griesel, B. A., Gurley, J. M., Szweda, L. I. & Olson, A. L., Jan 1 2017, In : Journal of Biological Chemistry. 292, 45, p. 18556-18564 9 p.

Research output: Contribution to journalArticle

Adipogenesis
Niacinamide
Facilitative Glucose Transport Proteins
Adipocytes
Metabolism
3 Citations (Scopus)

Homozygous Expression of Mutant ELOVL4 Leads to Seizures and Death in a Novel Animal Model of Very Long-Chain Fatty Acid Deficiency

Hopiavuori, B. R., deák, F., Wilkerson, J. L., Brush, R. S., Rocha-Hopiavuori, N. A., Hopiavuori, A. R., Ozan, K. G., Sullivan, M. T., Wren, J. D., Georgescu, C., Szweda, L., Awasthi, V., Towner, R., Sherry, D. M., Anderson, R. E. & Agbaga, M. P., Nov 22 2017, (Accepted/In press) In : Molecular Neurobiology. p. 1-19 19 p.

Research output: Contribution to journalArticle

Seizures
Viverridae
Fatty Acids
Animal Models
Lipids
158 Citations (Scopus)

Hypoxia induces heart regeneration in adult mice

Nakada, Y., Canseco, D. C., Thet, S., Abdisalaam, S., Aroumougame, A., Santos, C. X., Shah, A. M., Zhang, H., Faber, J. E., Kinter, M. T., Szweda, L. I., Xing, C., Hu, Z., DeBerardinis, R. J., Schiattarella, G., Hill, J. A., Oz, O. K., Lu, Z., Zhang, C., Kimura, W. & 1 others, Sadek, H. A., Jan 12 2017, In : Nature. 541, 7636, p. 222-227 6 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Regeneration
DNA Damage
Myocardium
Respiration
8 Citations (Scopus)

PPARα is essential for retinal lipid metabolism and neuronal survival

Pearsall, E. A., Cheng, R., Zhou, K., Takahashi, Y., Matlock, H. G., Vadvalkar, S. S., Shin, Y., Fredrick, T. W., Gantner, M. L., Meng, S., Fu, Z., Gong, Y., Kinter, M., Humphries, K. M., Szweda, L. I., Smith, L. E. H. & Ma, J. X., Nov 28 2017, In : BMC Biology. 15, 1, 113.

Research output: Contribution to journalArticle

PPAR alpha
Lipid Metabolism
lipid metabolism
metabolism
lipid
14 Citations (Scopus)

Regulation of pyruvate dehydrogenase kinase 4 in the heart through degradation by the lon protease in response to mitochondrial substrate availability

Crewe, C., Schafer, C., Lee, I., Kinter, M. & Szweda, L. I., Jan 6 2017, In : Journal of Biological Chemistry. 292, 1, p. 305-312 8 p.

Research output: Contribution to journalArticle

Protease La
Availability
Degradation
Substrates
Pyruvic Acid
2016
10 Citations (Scopus)

Catalase-dependent H2O2 consumption by cardiac mitochondria and redox-mediated loss in insulin signaling

Rindler, P. M., Cacciola, A., Kinter, M. & Szweda, L. I., Jan 1 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 5, p. H1091-H1096

Research output: Contribution to journalArticle

Catalase
Oxidation-Reduction
Mitochondria
Insulin
Peroxiredoxins
20 Citations (Scopus)

Nutrient sensing and utilization: Getting to the heart of metabolic flexibility

Griffin, T. M., Humphries, K. M., Kinter, M., Lim, H. Y. & Szweda, L. I., May 1 2016, In : Biochimie. 124, p. 74-83 10 p.

Research output: Contribution to journalReview article

Nutrients
Metabolism
Glucose
Food
Fatty Acids
6 Citations (Scopus)

Pyrophosphate-dependent ATP formation from acetyl coenzyme a in Syntrophus aciditrophicus, a new twist on ATP formation

James, K. L., Ríos-Hernández, L. A., Wofford, N. Q., Mouttaki, H., Sieber, J. R., Sheik, C. S., Nguyen, H. H., Yang, Y., Xie, Y., Erde, J., Rohlin, L., Karr, E. A., Loo, J. A., Loo, R. R. O., Hurst, G. B., Gunsalus, R. P., Szweda, L. I. & McInerney, M. J., Jul 1 2016, In : mBio. 7, 4, e01208-16.

Research output: Contribution to journalArticle

Acetyl Coenzyme A
Coenzymes
Acetate-CoA Ligase
Adenosine Triphosphate
Phosphate Acetyltransferase
2015
26 Citations (Scopus)

Lysine Acetylation Activates Mitochondrial Aconitase in the Heart

Fernandes, J., Weddle, A., Kinter, C. S., Humphries, K. M., Mather, T., Szweda, L. I. & Kinter, M., Jun 30 2015, In : Biochemistry. 54, 25, p. 4008-4018 11 p.

Research output: Contribution to journalArticle

Aconitate Hydratase
Acetylation
Lysine
Sirtuin 3
High Fat Diet
18 Citations (Scopus)

Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency

Griffith, A. V., Venables, T., Shi, J., Farr, A., van Remmen, H., Szweda, L., Fallahi, M., Rabinovitch, P. & Petrie, H. T., Aug 18 2015, In : Cell Reports. 12, 7, p. 1071-1079 9 p.

Research output: Contribution to journalArticle

Acatalasia
Premature Aging
Thymus
T-cells
Catalase
2014
16 Citations (Scopus)

Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity

Yao, L., Heuser-Baker, J., Herlea-Pana, O., Zhang, N., Szweda, L. I., Griffin, T. M. & Barlic-Dicen, J., Oct 1 2014, In : FASEB Journal. 28, 10, p. 4534-4550 17 p.

Research output: Contribution to journalArticle

Brown Adipose Tissue
Chemokine Receptors
Nutrition
Adipocytes
Obesity
1 Citation (Scopus)

Erratum: The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response (Cell (2014) 157 (741-743))

Puente, B. N., Kimura, W., Muralidhar, S. A., Moon, J., Amatruda, J. F., Phelps, K. L., Grinsfelder, D., Rothermel, B. A., Chen, R., Garcia, J. A., Santos, C. X., Thet, S., Mori, E., Kinter, M. T., Rindler, P. M., Zacchigna, S., Mukherjee, S., Chen, D. J., Mahmoud, A. I., Giacca, M. & 5 others, Rabinovitch, P. S., Asaithamby, A., Shah, A. M., Szweda, L. I. & Sadek, H. A., May 22 2014, In : Cell. 157, 5, p. 1243 1 p.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Cardiac Myocytes
DNA Damage
Oxygen
25 Citations (Scopus)

Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle

DeBalsi, K. L., Wong, K. E., Koves, T. R., Slentz, D. H., Seiler, S. E., Wittmann, A. H., Ilkayeva, O. R., Stevens, R. D., Perry, C. G. R., Lark, D. S., Hui, S. T., Szweda, L., Neufer, P. D. & Muoio, D. M., Mar 21 2014, In : Journal of Biological Chemistry. 289, 12, p. 8106-8120 15 p.

Research output: Contribution to journalArticle

Thioredoxins
Metabolomics
Mitochondrial Proteins
Muscle
Oxidoreductases
240 Citations (Scopus)

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response

Puente, B. N., Kimura, W., Muralidhar, S. A., Moon, J., Amatruda, J. F., Phelps, K. L., Grinsfelder, D., Rothermel, B. A., Chen, R., Garcia, J. A., Santos, C. X., Thet, S., Mori, E., Kinter, M. T., Rindler, P. M., Zacchigna, S., Mukherjee, S., Chen, D. J., Mahmoud, A. I., Giacca, M. & 5 others, Rabinovitch, P. S., Aroumougame, A., Shah, A. M., Szweda, L. I. & Sadek, H. A., Apr 24 2014, In : Cell. 157, 3, p. 565-579 15 p.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Cardiac Myocytes
DNA Damage
Cells
Oxygen
2013
Endocrinology
Lipid Peroxides
Islets of Langerhans
Type 2 Diabetes Mellitus
Adenosine Triphosphate
33 Citations (Scopus)

Glutathionylation of α-ketoglutarate dehydrogenase: The chemical nature and relative susceptibility of the cofactor lipoic acid to modification

McLain, A. L., Cormier, P. J., Kinter, M. & Szweda, L. I., May 9 2013, In : Free Radical Biology and Medicine. 61, p. 161-169 9 p.

Research output: Contribution to journalArticle

Thioctic Acid
Oxidoreductases
Glutathione
Disulfides
Enzymes
75 Citations (Scopus)

High dietary fat selectively increases catalase expression within cardiac mitochondria

Rindler, P. M., Plafker, S. M., Szweda, L. I. & Kinter, M., Jan 18 2013, In : Journal of Biological Chemistry. 288, 3, p. 1979-1990 12 p.

Research output: Contribution to journalArticle

Mitochondria
Dietary Fats
Catalase
Oxidative stress
Nutrition
9 Citations (Scopus)

Identification of ATP synthase as a lipid peroxide protein adduct in pancreatic islets from humans with and without type 2 diabetes mellitus

MacDonald, M. J., Langberg, E. C., Tibell, A., Sabat, G., Kendrick, M. A., Szweda, L. I. & Ostenson, C. G., Apr 1 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 4

Research output: Contribution to journalArticle

Lipid Peroxides
Medical problems
Islets of Langerhans
Type 2 Diabetes Mellitus
Adenosine Triphosphate
78 Citations (Scopus)

Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts

Allen, B. G., Bhatia, S. K., Buatti, J. M., Brandt, K. E., Lindholm, K. E., Button, A. M., Szweda, L. I., Smith, B. J., Spitz, D. R. & Fath, M. A., Jul 15 2013, In : Clinical Cancer Research. 19, 14, p. 3905-3913 9 p.

Research output: Contribution to journalArticle

Ketogenic Diet
Radio
Heterografts
Lung Neoplasms
Oxidative Stress
11 Citations (Scopus)

Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links

Perry, E. A., Castellani, R. J., Moreira, P. I., Nunomura, A., Lui, Q., Harris, P. L. R., Sayre, L. M., Szweda, P. A., Szweda, L. I., Zhu, X., Smith, M. A. & Perry, G., Jul 1 2013, In : Free Radical Research. 47, 6-7, p. 507-510 4 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Lysine
Lipids
Labeling
Lipid Peroxidation
66 Citations (Scopus)

Oxidative modification of lipoic acid by HNE in alzheimer disease brain

Hardas, S. S., Sultana, R., Clark, A. M., Beckett, T. L., Szweda, L. I., Paul Murphy, M. & Butterfield, D. A., Jan 1 2013, In : Redox Biology. 1, 1, p. 80-85 6 p.

Research output: Contribution to journalArticle

Thioctic Acid
Brain
Alzheimer Disease
Dihydrolipoamide Dehydrogenase
Oxidative stress
25 Citations (Scopus)

Rapid Inhibition of Pyruvate Dehydrogenase: An Initiating Event in High Dietary Fat-Induced Loss of Metabolic Flexibility in the Heart

Crewe, C., Kinter, M. & Szweda, L. I., Oct 7 2013, In : PLoS One. 8, 10, e77280.

Research output: Contribution to journalArticle

pyruvate dehydrogenase (lipoamide)
pyruvate dehydrogenase (acetyl-transferring) kinase
Dietary Fats
Nutrition
Pyruvic Acid
29 Citations (Scopus)

Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria

Rindler, P. M., Crewe, C. L., Fernandes, J., Kinter, M. & Szweda, L. I., Sep 1 2013, In : American Journal of Physiology - Heart and Circulatory Physiology. 305, 5

Research output: Contribution to journalReview article

Oxidation-Reduction
Insulin Resistance
Mitochondria
Fatty Acids
Glucose
2012
18 Citations (Scopus)

A Quantitative Proteomic Profile of the Nrf2-Mediated Antioxidant Response of Macrophages to Oxidized LDL Determined by Multiplexed Selected Reaction Monitoring

Kinter, C. S., Lundie, J. M., Patel, H., Rindler, P. M., Szweda, L. I. & Kinter, M., Nov 16 2012, In : PLoS One. 7, 11, e50016.

Research output: Contribution to journalArticle

Macrophages
low density lipoprotein
Proteomics
proteomics
macrophages
18 Citations (Scopus)

Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover

Zhu, X., Castellani, R. J., Moreira, P. I., Aliev, G., Shenk, J. C., Siedlak, S. L., Harris, P. L. R., Fujioka, H., Sayre, L. M., Szweda, P. A., Szweda, L. I., Smith, M. A. & Perry, G., Feb 1 2012, In : Free Radical Biology and Medicine. 52, 3, p. 699-704 6 p.

Research output: Contribution to journalArticle

Lipofuscin
Fluorophores
Crosslinking
Alzheimer Disease
Lipid Peroxidation
55 Citations (Scopus)

Mechanisms for Countering Oxidative Stress and Damage in Retinal Pigment Epithelium

Plafker, S. M., O'Mealey, G. B. & Szweda, L. I., Aug 14 2012, In : International Review of Cell and Molecular Biology. 298, p. 135-177 43 p.

Research output: Contribution to journalArticle

Oxidative stress
Retinal Pigments
Retinal Pigment Epithelium
Macular Degeneration
Oxidative Stress
2011
22 Citations (Scopus)

Proteasome alterations during adipose differentiation and aging: Links to impaired adipocyte differentiation and development of oxidative stress

Dasuri, K., Zhang, L., Ebenezer, P., Fernandez-Kim, S. O., Bruce-Keller, A. J., Szweda, L. I. & Keller, J. N., Nov 1 2011, In : Free Radical Biology and Medicine. 51, 9, p. 1727-1735 9 p.

Research output: Contribution to journalArticle

Oxidative stress
Proteasome Endopeptidase Complex
Adipocytes
Ubiquitin
Oxidative Stress
74 Citations (Scopus)

α-Ketoglutarate dehydrogenase: A mitochondrial redox sensor

McLain, A. L., Szweda, P. A. & Szweda, L. I., Jan 1 2011, In : Free Radical Research. 45, 1, p. 29-36 8 p.

Research output: Contribution to journalReview article

Oxidation-Reduction
Oxidoreductases
Thioctic Acid
Sensors
Glutaredoxins
2010
68 Citations (Scopus)

Ischaemic preconditioning improves proteasomal activity and increases the degradation of PKC during reperfusion

Churchill, E. N., Ferreira, J. C., Brum, P. C., Szweda, L. I. & Mochly-Rosen, D., Jan 1 2010, In : Cardiovascular Research. 85, 2, p. 385-394 10 p.

Research output: Contribution to journalArticle

Ischemic Preconditioning
Protein Kinase C
Reperfusion
Ischemia
Mitochondria
42 Citations (Scopus)

Ohr (organic hydroperoxide resistance protein) possesses a previously undescribed activity, lipoyl-dependent peroxidase

Cussiol, J. R. R., Alegria, T. G. P., Szweda, L. I. & Netto, L. E. S., Jul 16 2010, In : Journal of Biological Chemistry. 285, 29, p. 21943-21950 8 p.

Research output: Contribution to journalArticle

Hydrogen Peroxide
Peroxidase
Proteins
Xylella
Peroxiredoxins
2009
13 Citations (Scopus)

Mitochondrial superoxide production and respiratory activity: Biphasic response to ischemic duration

Matsuzaki, S., Szweda, L. I. & Humphries, K. M., Apr 1 2009, In : Archives of Biochemistry and Biophysics. 484, 1, p. 87-93 7 p.

Research output: Contribution to journalArticle

Superoxides
Ischemia
Electron Transport
Free Radicals
Mitochondria
18 Citations (Scopus)

Regulated production of free radicals by the mitochondrial electron transport chain: Cardiac ischemic preconditioning

Matsuzaki, S., Szweda, P. A., Szweda, L. I. & Humphries, K. M., Nov 30 2009, In : Advanced Drug Delivery Reviews. 61, 14, p. 1324-1331 8 p.

Research output: Contribution to journalReview article

Ischemic Preconditioning
Electron Transport
Free Radicals
Mitochondria
Oxidation-Reduction
2008
101 Citations (Scopus)

Hypoxia-inducible factor-2α transactivates Abcg2 and promotes cytoprotection in cardiac side population cells

Martin, C. M., Ferdous, A., Gallardo, T., Humphries, C., Sadek, H., Caprioli, A., Garcia, J. A., Szweda, L. I., Garry, M. G. & Garry, D. J., May 2008, In : Circulation Research. 102, 9, p. 1075-1081 7 p.

Research output: Contribution to journalArticle

Side-Population Cells
Cytoprotection
Stem Cells
Hydrogen Peroxide
Population
64 Citations (Scopus)

Intraretinal leakage and oxidation of LDL in diabetic retinopathy

Wu, M., Chen, Y., Wilson, K., Chirindel, A., Ihnat, M. A., Yu, Y., Boulton, M. E., Szweda, L. I., Ma, J. X. & Lyons, T. J., Jun 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 6, p. 2679-2685 7 p.

Research output: Contribution to journalArticle

Diabetic Retinopathy
LDL Lipoproteins
Pericytes
Macrophages
In Situ Nick-End Labeling
55 Citations (Scopus)

Pigment epithelium-derived factor mitigates inflammation and oxidative stress in retinal pericytes exposed to oxidized low-density lipoprotein

Zhang, S. X., Wang, J. J., Dashti, A., Wilson, K., Zou, M. H., Szweda, L., Ma, J. X. & Lyons, T. J., Sep 1 2008, In : Journal of Molecular Endocrinology. 41, 3-4, p. 135-143 9 p.

Research output: Contribution to journalArticle

Pericytes
Oxidative Stress
Inflammation
Chemokine CCL2
Reactive Oxygen Species
88 Citations (Scopus)

Reversible inhibition of α-ketoglutarate dehydrogenase by hydrogen peroxide: Glutathionylation and protection of lipoic acid

Applegate, M. A. B., Humphries, K. M. & Szweda, L. I., Jan 8 2008, In : Biochemistry. 47, 1, p. 473-478 6 p.

Research output: Contribution to journalArticle

Thioctic Acid
Hydrogen Peroxide
Oxidoreductases
Biotin
Mitochondria
2007
117 Citations (Scopus)

Autophagocytosis of mitochondria is prominent in Alzheimer disease

Moreira, P. I., Siedlak, S. L., Wang, X., Santos, M. S., Oliveira, C. R., Tabaton, M., Nunomura, A., Szweda, L. I., Aliev, G., Smith, M. A., Zhu, X. & Perry, G., Jun 1 2007, In : Journal of Neuropathology and Experimental Neurology. 66, 6, p. 525-532 8 p.

Research output: Contribution to journalArticle

Autophagy
Alzheimer Disease
Mitochondria
Thioctic Acid
Electron Transport Complex IV
45 Citations (Scopus)

Early myocardial dysfunction in streptozotocin-induced diabetic mice: A study using in vivo magnetic resonance imaging (MRI)

Yu, X., Tesiram, Y. A., Towner, R. A., Abbott, A., Patterson, E., Huang, S., Garrett, M. W., Chandrasekaran, S., Matsuzaki, S., Szweda, L. I., Gordon, B. E. & Kem, D. C., Mar 9 2007, In : Cardiovascular Diabetology. 6, 6.

Research output: Contribution to journalArticle

Streptozocin
Magnetic Resonance Imaging
Diabetic Cardiomyopathies
Stroke Volume
Long-Acting Insulin
1 Citation (Scopus)

Erratum: Autophagocytosis of mitochondria is prominent in Alzheimer disease (Journal of Neuropathology and Experimental Neurology (2007) 66, (525-532))

Moreira, P. I., Siedlak, S. L., Wang, X., Santos, M. S., Oliveira, C. R., Tabaton, M., Nunomura, A., Szweda, L. I., Aliev, G., Smith, M. A., Zhu, X. & Perry, G., Jul 1 2007, In : Journal of Neuropathology and Experimental Neurology. 66, 7, 1 p.

Research output: Contribution to journalComment/debate

107 Citations (Scopus)

Erratum: Increased autophagic degradation of mitochondria in Alzheimer disease (Autophagy)

Moreira, P. I., Siedlak, S. L., Wang, X., Santos, M. S., Oliveira, C. R., Tabaton, M., Nunomura, A., Szweda, L. I., Aliev, G., Smith, M. A., Zhu, X. & Perry, G., Jan 1 2007, In : Autophagy. 3, 6, p. 614-615 2 p.

Research output: Contribution to journalComment/debate

Biological Models
Autophagy
Alzheimer Disease
Mitochondria
Oxidative Stress
63 Citations (Scopus)

Hypoxia-inducible factor 2α regulates expression of the mitochondrial aconitase chaperone protein frataxin

Oktay, Y., Dioum, E., Matsuzaki, S., Ding, K., Yan, L. J., Haller, R. G., Szweda, L. I. & Garcia, J. A., Apr 20 2007, In : Journal of Biological Chemistry. 282, 16, p. 11750-11756 7 p.

Research output: Contribution to journalArticle

Aconitate Hydratase
Oxidative stress
Liver
Proteins
Mitochondrial Diseases
18 Citations (Scopus)
Submitochondrial Particles
Electron Transport
Superoxides
Free Radicals
Mitochondria