• 5346 Citations
  • 39 h-Index
1987 …2018
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Fingerprint Dive into the research topics where Margaret A Phillips is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Trypanosoma brucei brucei Medicine & Life Sciences
Ornithine Decarboxylase Medicine & Life Sciences
Adenosylmethionine Decarboxylase Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Plasmodium falciparum Medicine & Life Sciences
Polyamines Medicine & Life Sciences
Parasites Medicine & Life Sciences
African Trypanosomiasis Medicine & Life Sciences

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Research Output 1987 2018

  • 5346 Citations
  • 39 h-Index
  • 120 Article
  • 2 Chapter
  • 1 Short survey
  • 1 Review article
1 Citation (Scopus)
Adenosylmethionine Decarboxylase
Trypanosoma brucei brucei
16 Citations (Scopus)

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

Llanos-Cuentas, A., Casapia, M., Chuquiyauri, R., Hinojosa, J. C., Kerr, N., Rosario, M., Toovey, S., Arch, R. H., Phillips, M. A., Rozenberg, F. D., Bath, J., Ng, C. L., Cowell, A. N., Winzeler, E. A., Fidock, D. A., Baker, M., Möhrle, J. J., Hooft van Huijsduijnen, R., Gobeau, N., Araeipour, N. & 3 others, Andenmatten, N., Rückle, T. & Duparc, S., Jan 1 2018, (Accepted/In press) In : The Lancet Infectious Diseases.

Research output: Contribution to journalArticle

Vivax Malaria
Plasmodium falciparum
6 Citations (Scopus)

Assessing drug efficacy against Plasmodium falciparum liver stages in vivo

Flannery, E. L., Foquet, L., Chuenchob, V., Fishbaugher, M., Billman, Z., Navarro, M. J., Betz, W., Olsen, T. M., Lee, J., Camargo, N., Nguyen, T., Schafer, C., Sack, B. K., Wilson, E. M., Saunders, J., Bial, J., Campo, B., Charman, S. A., Murphy, S. C., Phillips, M. A. & 2 others, Kappe, S. H. & Mikolajczak, S. A., Jan 11 2018, In : JCI insight. 3, 1

Research output: Contribution to journalArticle

Open Access
Plasmodium falciparum
Pharmaceutical Preparations
2 Citations (Scopus)

Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265

White, J., Dhingra, S. K., Deng, X., El Mazouni, F., Lee, M. C. S., Afanador, G. A., Lawong, A., Tomchick, D. R., Ng, C. L., Bath, J., Rathod, P. K., Fidock, D. A. & Phillips, M. A., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Plasmodium falciparum
Point Mutation
5 Citations (Scopus)

Isoxazolopyrimidine-Based Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Antimalarial Activity

Kokkonda, S., El Mazouni, F., White, K. L., White, J., Shackleford, D. M., Lafuente-Monasterio, M. J., Rowland, P., Manjalanagara, K., Joseph, J. T., Garcia-Pérez, A., Fernandez, J., Gamo, F. J., Waterson, D., Burrows, J. N., Palmer, M. J., Charman, S. A., Rathod, P. K. & Phillips, M. A., Aug 31 2018, In : ACS Omega. 3, 8, p. 9227-9240 14 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
dihydroorotate dehydrogenase