• 71926 Citations
  • 119 h-Index
1984 …2020

Research output per year

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Research Output

Pharmacology of endothelins in vascular circuits of normal or heterozygous endothelin-A or endothelin-B knockout transgenic mice

Berthiaume, N., Yanagisawa, M., Yanagisawa, H., DeWit, D. & D'Orléans-Juste, P., Jan 1 1998, In : Journal of Cardiovascular Pharmacology. 31, SUPPL. 1, p. S561-S564

Research output: Contribution to journalArticle

14 Scopus citations

Phosphoinositide turnover signaling stimulated by ET-3 in endothelial cells from spontaneously hypertensive rats

Yokokawa, K., Johnson, J., Kohno, M., Mandal, A. K., Yanagisawa, M., Horio, T., Yasunari, K. & Takeda, T., 1994, In : AM.J.PHYSIOL.. 267, 3 part 2

Research output: Contribution to journalArticle

Phosphoinositide turnover signaling stimulated by ET-3 in endothelial cells from spontaneously hypertensive rats

Yokokawa, K., Johnson, J., Kohno, M., Mandal, A. K., Yanagisawa, M., Horio, T., Yasunari, K. & Takeda, T., Jan 1 1994, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 267, 3 36-3, p. R635-R644

Research output: Contribution to journalArticle

14 Scopus citations

Phosphoramidon inhibits the intracellular conversion of big endothelin-1 to endothelin-1 in cultured endothelial cells

Sawamura, T., Kasuya, Y., Matsushita, Y., Suzuki, N., Shinmi, O., Kishi, N., Sugita, Y., Yanagisawa, M., Goto, K., Masaki, T. & Kimura, S., Jan 31 1991, In : Biochemical and Biophysical Research Communications. 174, 2, p. 779-784 6 p.

Research output: Contribution to journalArticle

77 Scopus citations

Physiology and pharmacology of endothelins

Masaki, T., Yanagisawa, M. & Goto, K., Jul 1992, In : Medicinal Research Reviews. 12, 4, p. 391-421 31 p.

Research output: Contribution to journalArticle

247 Scopus citations

Plasma concentrations of endothelin-1 and endothelin-3 are altered differently in various pathophysiological conditions in humans

Miyauchi, T., Sugishita, Y., Yamaguchi, I., Ajisaka, R., Tomizawa, T., Onizuka, M., Matsuda, M., Kono, I., Yanagisawa, M., Goto, K., Suzuki, N., Matsumoto, H. & Masaki, T., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S394-S397

Research output: Contribution to journalArticle

30 Scopus citations

Polarized secretion of endothelin-1 and big ET-1 in MDCK cells is inhibited by cell Na+flux and disrupted by NH4Cl

Uchida, S., Horie, M., Yanagisawa, M., Matsushita, Y., Kurokawa, K. & Ogata, E., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S226-S228

Research output: Contribution to journalArticle

15 Scopus citations

Positive chronotropic effects of endothelin, a novel endothelium-derived vasoconstrictor peptide

Ishikawa, T., Yanagisawa, M., Kimura, S., Goto, K. & Masaki, T., Nov 1 1988, In : Pflügers Archiv European Journal of Physiology. 413, 1, p. 108-110 3 p.

Research output: Contribution to journalArticle

181 Scopus citations

Positive inotropic action of novel vasoconstrictor peptide endothelin on guinea pig atria

Ishikawa, T., Yanagisawa, M., Kimura, S., Goto, K. & Masaki, T., Jan 1 1988, In : American Journal of Physiology - Heart and Circulatory Physiology. 255, 4, p. 24/4

Research output: Contribution to journalArticle

336 Scopus citations

Possible role of endothelin in the pathogenesis of cerebral vasospasm

Shigeno, T., Mima, T., Yanagisawa, M., Saito, A., Fujimori, A., Shiba, R., Goto, K., Kimura, S., Yamashita, K., Yamasaki, Y., Masaki, T. & Takakura, K., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S480-S483

Research output: Contribution to journalArticle

21 Scopus citations

Presence and distribution of endothelin-1 gene expression in human kidney

Pupilli, C., Brunori, M., Misciglia, N., Selli, C., Ianni, L., Yanagisawa, M., Mannelli, M. & Serio, M., Jan 1 1994, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 267, 4 36-4, p. F679-F687

Research output: Contribution to journalArticle

51 Scopus citations

Presence and distribution of endothelin-1 gene expression in human kidney

Pupilli, C., Brunori, M., Misciglia, N., Selli, C., Ianni, L., Yanagisawa, M., Mannelli, M. & Serio, M., 1994, In : AM.J.PHYSIOL.. 267, 4 part 2

Research output: Contribution to journalArticle

Presence of endothelin-1 in porcine spinal cord: Isolation and sequence determination

Shinmi, O., Kimura, S., Yoshizawa, T., Sawamura, T., Uchiyama, Y., Sugita, Y., Kanazawa, I., Yanagisawa, M., Goto, K. & Masaki, T., Jul 14 1989, In : Biochemical and Biophysical Research Communications. 162, 1, p. 340-346 7 p.

Research output: Contribution to journalArticle

97 Scopus citations

Pressor Response to Endothelin in Guinea Pigs

Li, L., Ishikawa, T., Miyauchi, T., Yanagisawa, M., Kimura, S., Goto, K. & Masaki, T., Jan 1 1988, In : the japanese journal of pharmacology. 49, 4, p. 549-552 4 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Prevention of cerebral vasospasm by actinomycin D

Shigeno, T., Mima, T., Yanagisawa, M., Siato, A., Goto, K., Yamashita, K., Takenouchi, T., Matsuura, N., Yamasaki, Y., Yamada, K., Masaki, T. & Takakura, K., Jan 1 1991, In : Journal of neurosurgery. 74, 6, p. 940-943 4 p.

Research output: Contribution to journalArticle

36 Scopus citations

Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide

Yanagisawa, M., Inoue, A., Ishikawa, T., Kasuya, Y., Kimura, S., Kumagaye, S., Nakajima, K., Watanabe, T. X., Sakakibara, S., Goto, K. & Masaki, T., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 18, p. 6964-6967 4 p.

Research output: Contribution to journalArticle

Open Access
531 Scopus citations

Primary structure of chicken skeletal muscle and fibroblast α‐actinins deduced from cDNA sequences

ARIMURA, C., SUZUKI, T., YANAGISAWA, M., IMAMURA, M., HAMADA, Y. & MASAKI, T., Jan 1 1988, In : European Journal of Biochemistry. 177, 3, p. 649-655 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Production of endothelin-1 by rat cultured mesangial cells

Sakamoto, H., Sasaki, S., Hirata, Y., Imai, T., Ando, K., Ida, T., Sakurai, T., Yanagisawa, M., Masaki, T. & Marumo, F., Jun 15 1990, In : Biochemical and Biophysical Research Communications. 169, 2, p. 462-468 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Progress report on the Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) study: Status at February 2004

Hosohata, K., Saito, S., Asayama, K., Ohkubo, T., Kikuya, M., Metoki, H., Obara, T., Kato, T., Hashimoto, J., Totsune, K., Miura, Y., Imai, Y., Arakawa, K., Fujishima, M., Fujii, J., Fukiyama, K., Hisamichi, S., Iimura, O., Ishii, M., Omae, T. & 526 others, Saruta, T., Yoshinaga, K., Abe, I., Abe, K., Abukawa, T., Ashida, T., Dohba, N., Etoh, T., Fujimura, A., Fujita, T., Fukui, A., Gotoh, T., Hama, H., Hano, T., Hayashi, H., Hayashida, N., Hayashi, M., Hiramori, K., Hirai, Y., Hirata, Y., Hiwada, K., Hora, K., Ichikawa, S., Iida, T., Ikeda, T., Imaizumi, T., Ishikawa, K., Ito, I., Ito, M., Ito, S., Iwaoka, D., Kanamasa, K., Katagiri, T., Katayama, S., Kawamura, H., Kawano, Y., Kida, H., Kikuchi, K., Kimura, G., Kimura, K., Kitaoka, H., Kobayashi, S., Kohara, K., Kojima, S., Komuro, I., Kumagai, H., Kumagai, Y., Kusano, E., Kushiro, T., Kuwajima, I., Maruyama, Y., Masani, F., Matsubara, H., Matsubara, T., Matsumoto, M., Matsuoka, H., Matsuura, H., Mishima, Y., Miura, M., Miyamori, I., Mori, H., Murakami, H., Muratani, H., Nakagawa, M., Nakao, K., Naruse, M., Nishio, I., Ogihara, T., Ohta, M., Ohtsuka, K., Ohtsuka, Y., Ohuchi, Y., Oikawa, S., Okabe, M., Okumura, K., Saitoh, I., Saitoh, H., Sakata, T., Saku, K., Sasaki, H., Seino, M., Senda, S., Shimada, K., Shimamoto, K., Shimizu, M., Shiomi, T., Shirato, K., Sone, M., Suzuki, H., Suzuki, S., Takahashi, H., Takada, M., Takeda, K., Takeda, N., Takeshita, A., Takishita, S., Tanaka, S., Toba, K., Tochikubo, O., Tomoike, H., Ueno, Y., Umemura, S., Urata, H., Watanabe, T., Yamada, K., Yamaguchi, T., Yamakado, M., Yamamoto, Y., Yamamoto, Y., Yamashina, A., Yokoyama, H., Yoshimura, M., Satoh, H., Oka, Y., Katagiri, H., Kondo, Y., Shishido, H., Kohinata, A., Kanno, Y., Ikeda, H., Takahira, Y., Takahashi, T., Kimura, A., Funahashi, J., Takada, N., Hanazawa, T., Suzuki, N., Osugi, M., Hashimoto, J., Ogawa, Y., Miyamura, T., Masuda, Y., Tanaka, S., Tanaka, S., Koizumi, M., Ando, T., Endo, T., Tsuchida, A., Nanba, M., Yonekura, S., Shiroishi, M., Nakagawa, M., Ito, K., Oda, K., Takahashi, K., Kanahara, I., Hirota, N., Tsutsui, M., Anzai, J., Hosoda, S., Shiiki, M., Takagawa, Y., Iida, M., Tada, M., Noto, T., Tanaka, H., Tajima, G., Kawamorita, K., Kikuchi, K., Suzuki, H., Suzuki, K., Komai, K., Seki, H., Omoto, A., Takahashi, H., Kitabayashi, A., Kimura, M., Kimura, Y., Yamamoto, H., Takahashi, K., Kimura, H., Kawamorita, Y., Emura, Y., Suzuki, Y., Ishikawa, Y., Nagai, K., Nagai, S., Ito, T., Nihei, K., Yamada, S., Goto, T., Yamamoto, N., Suzuki, Y., Ito, H., Ito, M., Fujita, T., Tominaga, Y., Tominaga, S., Suzuki, K., Ishibashi, K., Ando, Y., Sato, S., Morikawa, H., Kashima, S., Nakayama, D., Hayashi, Y., Ohta, K., Metoki, H., Fukami, K., Hayashi, T., Kishi, M., Tajima, J., Seino, J., Hoshi, H., Imai, Y., Kimura, H., Mori, R., Matsuo, K., Tanno, Y., Shibasaki, A., Yamagishi, T., Ohtomo, E., Ohtsuka, Y., Sasaki, S., Seino, M., Kurosawa, K., Ito, K., Takagi, Y., Kyogoku, S., Ito, K., Ono, Y., Watanabe, M., Watanabe, S., Hiwatashi, N., Yagi, C., Unakami, H., Asayama, K., Mouri, T., Watanabe, T., Kikuchi, K., Maruyama, N., Sone, M., Iwamoto, M., Naganuma, S., Mashiko, H., Ishii, H., Takaya, Y., Kamimoto, M., Shirai, A., Watanabe, R., Tohyama, Y., Araki, F., Sakuma, H., Amada, Y., Sato, E., Techigawara, M., Nakamura, K., Nakayama, T., Hasegawa, K., Hasegawa, K., Nagao, T., Minami, J., Kumagai, Y., Cho, T., Okamoto, K., Iguchi, T., Honzawa, T., Koitabashi, T., Yamada, T., Horikoshi, H., Nagao, T., Yoshimatsu, H., Seki, K., Akiyama, N., Suga, H., Matsunaga, R., Sinozaki, T., Ishimaru, Y., Yagi, N., Takikawa, H., Hukutome, T., Nakajima, C., Sato, H., Simizu, J., Arai, M., Koide, H., Takada, H., Sato, T., Umezu, T., Aoki, H., Nakamoto, H., Komahashi, K., Sekiya, S., Sugimoto, H., Arai, T., Suzuki, H., Inokuma, S., Funazaki, T., Yasuda, F., Kanouzawa, S., Yokota, C., Noguchi, Y., Hatano, M., Izumida, T., Hara, T., Muranaka, H., Suzuki, M., Ogawa, Y., Yabumoto, E., Matsushita, S., Kohzu, K., Sasaki, F., Hata, N., Yanagisawa, M., Ueda, T., Kurosawa, M., Doutare, S., Higashi, S., Kato, M., Hoshino, T., Fukuda, K., Ohtsuki, K., Ikeda, T., Kasatani, T., Yamada, T., Yatagai, S., Ohsuga, E., Yamakado, M., Kawamura, H., Mitsubayashi, H., Yamashina, S., Yamazaki, J., Nanjo, S., Ito, S., Teramoto, T., Gomi, T., Kato, S., Koekawa, N., Kuwaki, K., Ikeda, T., Hori, K., Arai, S., Koyama, H., Ichikawa, M., Hashimoto, A., Mori, H., Abe, S., Ohba, Y., Kurata, F., Miyakawa, M., Kimura, K., Hatori, Y., Ushiyama, M., Yamamoto, H., Adachi, M., Takayama, K., Shimizu, M., Iida, T., Asato, S., Uchiba, K., Watanabe, N., Kotani, M., Akaoka, F., Takahashi, S., Hirahara, K., Suzuki, S., Yamaguchi, Y., Ishikawa, S., Sasaki, K., Terada, Y., Ohhashi, S., Sakamaki, A., Hifumi, N., Ohno, T., Saeki, T., Suzaki, Y., Yamamoto, H., Nakagawa, T., Tomoda, F., Nishino, H., Ise, T., Takakuwa, H., Yokoyama, H., Kitakawa, S., Takasawa, K., Ohkura, T., Yamamoto, Y., Satake, K., Arai, Y., Nakayama, H., Sugiyama, S., Sugiura, K., Yokoyama, M., Ito, A., Okazaki, K., Saito, R., Mihara, J., Naito, A., Takahira, Y., Mori, T., Watanabe, M., Asai, S., Nojiri, O., Sakakura, K., Kozuka, M., Oyama, Y., Kawamura, Y., Inoko, T., Takeuchi, N., Tatematsu, H., Hayakawa, Y., Adachi, N., Tamagaki, N., Nakamura, T., Fukui, A., Amenomori, M., Kanaya, T., Masui, A., Hayashi, K., Nishi, S., Amari, M., Yoshida, K., Matsushita, Y., Sawada, S., Fujiwara, M., Ono, S., Tamai, K., Takemoto, Y., Kanemasa, T., Takenaka, T., Kitayama, K., Yasui, K., Fujita, S., Terayama, Y., Kato, N., Nagai, M., Takashima, H., Watanabe, K., Hirobe, N., Miyamoto, M., Sakamoto, N., Kurimoto, Y., Suzuki, N., Katsuya, S., Katsuya, T., Nagao, K., Nakamuta, K., Goto, S., Ueda, T., Imai, N., Sano, I., Ueda, H., Takahashi, N., Sada, T., Iwane, M., Suzuki, H., Yoshikawa, H., Tominaga, Y., Kamura, M., Ohtahara, A., Nakamura, Y., Osakada, M., Gen, M., Kahara, M., Yoshimoto, T., Mizuno, K., Furukawa, Y., Tokunaga, A., Sasaki, N., Matsumura, M., Furue, T., Iwasaki, K., Ichiki, K., Mizofuchi, S., Yokoi, T., Furumoto, W., Fukui, T., Fujino, K., Ohta, A., Ueda, S., Kitami, Y., Ohkura, T., Takeuchi, M., Yoshida, K., Nishiyama, S., Kawamoto, R., Kobaru, A., Endo, T., Kitano, K., Hirooka, Y., Tohaya, M., Miyazaki, Y., Onoyama, K., Miyagi, J., Kin, U., Fujishima, Y., Kuwahara, A., Shindo, R., Satake, Y., Moritsuka, T., Kuwahara, T., Hano, O., Takagi, Y., Suzuki, S., Abe, K., Sato, T., Kohno, M., Fujino, T., Wakayama, K., Aso, T., Goto, T., Ozaki, H., Ninomiya, K., Inobe, Y., Hamasaki, S., Inoue, J., Naomi, S., Iwaoka, T., Ono, T., Muta, Y., Endo, Y., Ohmori, H., Nagata, M., Wake, N., Kozawa, H., Tomino, Y., Ikeda, T., Yoshii, H., Nakamura, H., Fujimoto, N., Asato, T., Tozawa, M., Sunagawa, R., Nakamura, Y., Tomori, H. & Takashiba, K., Jan 1 2007, In : Clinical and Experimental Hypertension. 29, 1, p. 69-81 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Pseudo-Noncompetitive Antagonism by BQ123 of Intracellular Calcium Transients Mediated by Human ETA Endothelin Receptor

Sakamoto, A., Yanagisawa, M., Tsujimoto, G., Nakao, K., Toyooka, T. & Masaki, T., Jan 1 1994, In : Biochemical and Biophysical Research Communications. 200, 2, p. 679-686 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Pulmonary disease models induced by in vivo hemagglutinating virus of Japan liposome-mediated endothelin-1 gene transfer

Takeda, S. I., Miyoshi, S., Omori, K. I., Utsumi, T., Kogaki, S., Sawa, Y., Yanagisawa, M. & Matsuda, H., Jan 1 1998, In : Journal of Cardiovascular Pharmacology. 31, SUPPL. 1, p. S336-S338

Research output: Contribution to journalArticle

4 Scopus citations

Purification and characterization of putative endothelin converting enzyme in bovine adrenal medulla: Evidence for a cathepsin D-like enzyme

Sawamura, T., Kimura, S., Shinmi, O., Sugita, Y., Yanagisawa, M., Goto, K. & Masaki, T., May 16 1990, In : Biochemical and Biophysical Research Communications. 168, 3, p. 1230-1236 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

QRFP-Deficient mice are hypophagic, lean, hypoactive and exhibit increased anxiety-Like behavior

Okamoto, K., Yamasaki, M., Takao, K., Soya, S., Iwasaki, M., Sasaki, K., Magoori, K., Sakakibara, I., Miyakawa, T., Mieda, M., Watanabe, M., Sakai, J., Yanagisawa, M. & Sakurai, T., Nov 2016, In : PloS one. 11, 11, e0164716.

Research output: Contribution to journalArticle

7 Scopus citations

Quantitative measurement of GPCR endocytosis via pulse-chase covalent labeling

Kumagai, H., Ikeda, Y., Motozawa, Y., Fujishiro, M., Okamura, T., Fujio, K., Okazaki, H., Nomura, S., Takeda, N., Harada, M., Toko, H., Takimoto, E., Akazawa, H., Morita, H., Suzuki, J. I., Yamazaki, T., Yamamoto, K., Komuro, I. & Yanagisawa, M., May 28 2015, In : PLoS One. 10, 5, e0129394.

Research output: Contribution to journalArticle

4 Scopus citations

Quantitative phosphoproteomic analysis of the molecular substrates of sleep need

Wang, Z., Ma, J., Miyoshi, C., Li, Y., Sato, M., Ogawa, Y., Lou, T., Ma, C., Gao, X., Lee, C., Fujiyama, T., Yang, X., Zhou, S., Hotta-Hirashima, N., Klewe-Nebenius, D., Ikkyu, A., Kakizaki, M., Kanno, S., Cao, L., Takahashi, S. & 5 others, Peng, J., Yu, Y., Funato, H., Yanagisawa, M. & Liu, Q., Jun 21 2018, In : Nature. 558, 7710, p. 435-439 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Rediscovering an endothelin antagonist (BQ-123): A self-deconvoluting cyclic pentapeptide library

Spatola, A. F., Crozet, Y., DeWit, D. & Yanagisawa, M., Sep 13 1996, In : Journal of Medicinal Chemistry. 39, 19, p. 3842-3846 5 p.

Research output: Contribution to journalArticle

51 Scopus citations
21 Scopus citations

Reduced expression of the endothelin receptor type B gene in piebald mice caused by insertion of a retroposon-like element in intron 1

Yamada, T., Ohtani, S., Sakurai, T., Tsuji, T., Kunieda, T. & Yanagisawa, M., Apr 21 2006, In : Journal of Biological Chemistry. 281, 16, p. 10799-10807 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

REGISTRATION OF LOCALLY DISTORTED IMAGES BY MULTIWINDOW PATTERN MATCHING AND DISPLACEMENT INTERPOLATION: THE PROPOSAL OF AN ALGORITHM AND ITS APPLICATION TO DIGITAL SUBTRACTION ANGIOGRAPHY.

Yanagisawa, M., Shigemitsu, S. & Akatsuka, T., Dec 1 1984, Proceedings - International Conference on Pattern Recognition. IEEE, p. 1288-1291 4 p. (Proceedings - International Conference on Pattern Recognition; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

23 Scopus citations

Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor

Clines, G. A., Mohammad, K. S., Grunda, J. M., Clines, K. L., Niewolna, M., McKenna, C. R., McKibbin, C. R., Yanagisawa, M., Suva, L. J., Chirgwin, J. M. & Guise, T. A., Oct 1 2011, In : Journal of Bone and Mineral Research. 26, 10, p. 2523-2536 14 p.

Research output: Contribution to journalArticle

23 Scopus citations

Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells

Oike, Y., Ito, Y., Hamada, K., Zhang, X. Q., Miyata, K., Arai, F., Inada, T., Araki, K., Nakagata, N., Takeya, M., Kisanuki, Y. Y., Yanagisawa, M., Gale, N. W. & Suda, T., Aug 15 2002, In : Blood. 100, 4, p. 1326-1333 8 p.

Research output: Contribution to journalArticle

Open Access
102 Scopus citations

Renal tubular effects of endothelin-B receptor signaling: Its role in cardiovascular homeostasis and extracellular volume regulation

Ohuchi, T., Yanagisawa, M. & Gariepy, C. E., Jul 24 2000, In : Current opinion in nephrology and hypertension. 9, 4, p. 435-439 5 p.

Research output: Contribution to journalReview article

26 Scopus citations

Renal vasoconstriction by the endothelial cell-derived peptide endothelin in spontaneously hypertensive rats

Hirata, Y., Matsuoka, H., Kimura, K., Fukui, K., Hayakawa, H., Suzuki, E., Sugimoto, T., Sugimoto, T., Yanagisawa, M. & Masaki, T., Jan 1 1989, In : Circulation research. 65, 5, p. 1370-1379 10 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations

Rodent models of human narcolepsy-cataplexy

Sakurai, T., Yanagisawa, M. & Mieda, M., Jan 1 2005, Hypocretins: Integrators of Physiological Functions. Springer US, p. 27-38 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Role of cardiac myocyte-derived endothelin-1 in chagasic cardiomyopathy: Molecular genetic evidence

Huang, H., Yanagisawa, M., Kisanuki, Y. Y., Jelicks, L. A., Chandra, M., Factor, S. M., Wittner, M., Weiss, L. M., Pestell, R. G., Shtutin, V., Shirani, J. & Tanowitz, H. B., Aug 1 2002, In : Clinical science. 103, SUPPL. 48, p. 263S-266S

Research output: Contribution to journalArticle

20 Scopus citations

Role of D1x6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer

Charité, J., McFadden, D. G., Merlo, G., Levi, G., Clouthier, D. E., Yanagisawa, M., Richardson, J. A. & Olson, E. N., Nov 15 2001, In : Genes and Development. 15, 22, p. 3039-3049 11 p.

Research output: Contribution to journalArticle

98 Scopus citations

Role of endothelin-1/endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice

Yanagisawa, H., Hammer, R. E., Richardson, J. A., Williams, S. C., Clouthier, D. E. & Yanagisawa, M., Jul 1 1998, In : Journal of Clinical Investigation. 102, 1, p. 22-33 12 p.

Research output: Contribution to journalArticle

Open Access
164 Scopus citations

Role of endothelin 1 in the pathogenesis of chronic chagasic heart disease

Tanowitz, H. B., Huang, H., Jelicks, L. A., Chandra, M., Loredo, M. L., Weiss, L. M., Factor, S. M., Shtutin, V., Mukherjee, S., Kitsis, R. N., Christ, G. J., Wittner, M., Shirani, J., Kisanuki, Y. Y. & Yanagisawa, M., Apr 1 2005, In : Infection and immunity. 73, 4, p. 2496-2503 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Role of endothelin ETB receptor in partial ablation-induced chronic renal failure in rats

Okada, Y., Nakata, M., Izumoto, H., Takasu, M., Tazawa, N., Takaoka, M., Gariepy, C. E., Yanagisawa, M. & Matsumura, Y., Jun 21 2004, In : European Journal of Pharmacology. 494, 1, p. 63-71 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Role of endothelin ET B receptor in the pathogenesis of monocrotaline-induced pulmonary hypertension in rats

Nishida, M., Okada, Y., Akiyoshi, K., Eshiro, K., Takaoka, M., Gariepy, C. E., Yanagisawa, M. & Matsumura, Y., Aug 2 2004, In : European Journal of Pharmacology. 496, 1-3, p. 159-165 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Role of endothelin ETB receptors in the renal hemodynamic and excretory responses to big endothelin-1

Konishi, F., Okada, Y., Takaoka, M., Gariepy, C. E., Yanagisawa, M. & Matsumura, Y., Sep 13 2002, In : European Journal of Pharmacology. 451, 2, p. 177-184 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Role of endothelin in mechanisms of local blood pressure control

Masaki, T., Yanagisawa, M., Goto, K. & Kimura, S., Dec 1 1990, In : Journal of hypertension. 8, SUPPL. 7, p. S107-S112

Research output: Contribution to journalArticle

32 Scopus citations

Role of endothelin in the development of dahl hypertension

Goligorsky, M. S., Iijima, K., Morgan, M., Yanagisawa, M., Masaki, T., Lin, L., Nasjletti, A., Kaskel, F., Frazer, M. & Badr, K. F., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S484-S491

Research output: Contribution to journalArticle

25 Scopus citations

Role of hypothalamic orexin neurons in the regulation of arousal according to energy balance

Yamanaka, A., Beuckmann, C. T., Willie, J. T., Hara, J., Tsujino, N., Goto, K., Yanagisawa, M. & Sakurai, T., May 1 2004, In : Sleep and Biological Rhythms. 2, SUPPL. 1, p. S57

Research output: Contribution to journalArticle

Role of tyrosine kinase pathways in ET(B) receptor activation of NHE3

Chu, T. S., Tsuganezawa, H., Peng, Y., Cano, A., Yanagisawa, M. & Alpern, R. J., Sep 1 1996, In : American Journal of Physiology - Cell Physiology. 271, 3 40-3, p. C763-C771

Research output: Contribution to journalArticle

36 Scopus citations

Roles of forkhead transcription factor Foxc2 (MFH-1) and endothelin receptor a in cardiovascular morphogenesis

Kanzaki-Kato, N., Tamakoshi, T., Fu, Y., Chandra, A., Itakura, T., Uezato, T., Tanaka, T., Clouthier, D. E., Sugiyama, T., Yanagisawa, M. & Miura, N., Feb 15 2005, In : Cardiovascular Research. 65, 3, p. 711-718 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Salt-sensitive hypertension in endothelin-B receptor-deficient rats

Gariepy, C. E., Ohuchi, T., Williams, S. C., Richardson, J. A. & Yanagisawa, M., Apr 2000, In : Journal of Clinical Investigation. 105, 7, p. 925-933 9 p.

Research output: Contribution to journalArticle

Open Access
246 Scopus citations

Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture

Matsuki, T., Nomiyama, M., Takahira, H., Hirashima, N., Kunita, S., Takahashi, S., Yagami, K. I., Kilduff, T. S., Bettler, B., Yanagisawa, M. & Sakurai, T., Mar 17 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 11, p. 4459-4464 6 p.

Research output: Contribution to journalArticle

88 Scopus citations

Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 11, (4459-4464) DOI: 10.1073/pnas.0811126106)

Matsuki, T., Nomiyama, M., Takahira, H., Hirashima, N., Kunita, S., Takahashi, S., Yagami, K. I., Kilduff, T. S., Bettler, B., Yanagisawa, M. & Sakurai, T., May 26 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 21, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Sensitivity of orexin-A binding to phospholipase C inhibitors, neuropeptide Y, and secretin

Kane, J. K., Tanaka, H., Parker, S. L., Yanagisawa, M. & Li, M. D., Jun 16 2000, In : Biochemical and Biophysical Research Communications. 272, 3, p. 959-965 7 p.

Research output: Contribution to journalArticle

39 Scopus citations