• 71419 Citations
  • 119 h-Index
1984 …2019

Research output per year

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Research Output

  • 71419 Citations
  • 119 h-Index
  • 451 Article
  • 3 Chapter
  • 3 Conference contribution
1991

Characterization of the effect of endothelins in canine cerebral arteries

Saito, A., Shiba, R., Yanagisawa, M., Masaki, T., Kimura, S., Yamada, K., Mima, T., Shigeno, T. & Goto, K., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

1 Scopus citations

Chromosomal assignments of the human endothelin family genes: The endothelin-1 gene (EDN1) to 6p23-p24, the endothelin-2 gene (EDN2) to 1p34, and the endothelin-3 gene (EDN3) to 20q13.2-q13.3

Arinami, T., Ishikawa, M., Inoue, A., Yanagisawa, M., Masaki, T., Yoshida, M. C. & Hamaguchi, H., May 1991, In : American Journal of Human Genetics. 48, 5, p. 990-996 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Cloning and functional expression of human cDNA for the ETB endothelin receptor

Sakamoto, A., Yanagisawa, M., Sakurai, T., Takuwa, Y., Yanagisawa, H. & Masaki, T., Jul 31 1991, In : Biochemical and Biophysical Research Communications. 178, 2, p. 656-663 8 p.

Research output: Contribution to journalArticle

240 Scopus citations

Comparison of endothelin-1 concentrations in normal and complicated pregnancies

Otani, S., Usuki, S., Saitoh, T., Yanagisawa, M., Iwasaki, H., Tanaka, J., Suzuki, N., Fujino, M., Goto, K. & Masaki, T., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

12 Scopus citations

Elevated plasma levels of endothelin-1 in systemic sclerosis [2]

Yamane, K., Kashiwagi, H., Suzuki, N., Miyauchi, T., Yanagisawa, M., Goto, K. & Masaki, T., 1991, In : Arthritis and Rheumatism. 34, 2, p. 243-244 2 p.

Research output: Contribution to journalArticle

68 Scopus citations

Endothelin-1 in luteal tissue

Usuki, S., Suzuki, N., Matsumoto, H., Yanagisawa, M. & Masaki, T., 1991, In : Molecular and Cellular Endocrinology. 80, 1-3, p. 147-151 5 p.

Research output: Contribution to journalArticle

37 Scopus citations

Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines

Shichiri, M., Hirata, Y., Nakajima, T., Ando, K., Imai, T., Yanagisawa, M., Masaki, T. & Marumo, F., May 1991, In : Journal of Clinical Investigation. 87, 5, p. 1867-1871 5 p.

Research output: Contribution to journalArticle

195 Scopus citations

Endothelin induces DNA polymerase α activity in ovaries of hypophysectomized estrogen-treated immature rats

Usuki, S., Otani, S., Goto, K., Matsumoto, H., Suzuki, N., Yanagisawa, M. & Masaki, T., 1991, In : Hormone and Metabolic Research. 23, 12, p. 621-622 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Endothelin in perinatal pharmacology

Masaki, T., Usuki, S., Yanagisawa, M. & Suzuki, N., 1991, In : Seminars in Perinatology. 15, 1, p. 27-29 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Endothelins: Vasoconstrictor effects and localization in canine cerebral arteries

Saito, A., Shiba, R., Yanagisawa, M., Masaki, T., Kimura, S., Yamada, K., Mima, T., Shigeno, T. & Goto, K., 1991, In : British Journal of Pharmacology. 103, 1, p. 1129-1135 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Endothelin-secreting tumor

Yokokawa, K., Tahara, H., Kohno, M., Murakawa -i., K., Yasunari, K., Nakagawa, K., Hamada, T., Otani, S., Yanagisawa, M. & Takeda, T., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

12 Scopus citations

Expression of endothelin-like peptide in the nervous system of the marine mollusk Aplysia

Giaid, A., Masaki, T., Ouimet, T., Yanagisawa, M., Gaspar, L., Cantin, M., Kimura, S. & Castellucci, V. F., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

9 Scopus citations

Hypertension associated with endothelin-secreting malignant hemangioendothelioma

Yokokawa, K., Tahara, H., Kohno, M., Murakawa, K. I., Yasunari, K., Nakagawa, K., Hamada, T., Otani, S., Yanagisawa, M. & Takeda, T., Feb 1 1991, In : Annals of Internal Medicine. 114, 3, p. 213-215 3 p.

Research output: Contribution to journalArticle

155 Scopus citations

Increased plasma concentrations of endothelin-1 during and after pulmonary surgery

Onizuka, M., Miyauchi, T., Morita, R., Akaogi, E., Mitsui, K., Suzuki, N., Fujino, M., Yanagisawa, M., Goto, K., Masaki, T. & Hori, M., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

10 Scopus citations

Increased plasma level of endothelin-1 and coronary spasm induction in patients with vasospastic angina pectoris

Toyo-oka, T., Aizawa, T., Suzuki, N., Hirata, Y., Miyauchi, T., Shin, W. S., Yanagisawa, M., Masaki, T. & Sugimoto, T., Feb 1991, In : Circulation. 83, 2, p. 476-483 8 p.

Research output: Contribution to journalArticle

225 Scopus citations

Mechanisms of altered sensitivity to endothelin-1 between aortic smooth muscles of spontaneously hypertensive and Wistar-Kyoto rats

Tomobe, Y., Ishikawa, T., Yanagisawa, M., Kimura, S., Masaki, T. & Goto, K., 1991, In : Journal of Pharmacology and Experimental Therapeutics. 257, 2, p. 555-561 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Mechanisms of endothelin-1 mRNA and peptides induction by TGF-β and TPA in MDCK cells

Horie, M., Uchida, S., Yanagisawa, M., Matsushita, Y., Kurokawa, K. & Ogata, E., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

16 Scopus citations

Molecular and cellular mechanism of endothelin regulation: Implications for vascular function

Masaki, T., Kimura, S., Yanagisawa, M. & Goto, K., Oct 1991, In : Circulation. 84, 4, p. 1457-1468 12 p.

Research output: Contribution to journalArticle

397 Scopus citations

Phosphoramidon inhibits the intracellular conversion of big endothelin-1 to endothelin-1 in cultured endothelial cells

Sawamura, T., Kasuya, Y., Matsushita, Y., Suzuki, N., Shinmi, O., Kishi, N., Sugita, Y., Yanagisawa, M., Goto, K., Masaki, T. & Kimura, S., Jan 31 1991, In : Biochemical and Biophysical Research Communications. 174, 2, p. 779-784 6 p.

Research output: Contribution to journalArticle

77 Scopus citations

Plasma concentrations of endothelin-1 and endothelin-3 are altered differently in various pathophysiological conditions in humans

Miyauchi, T., Sugishita, Y., Yamaguchi, I., Ajisaka, R., Tomizawa, T., Onizuka, M., Matsuda, M., Kono, I., Yanagisawa, M., Goto, K., Suzuki, N., Matsumoto, H. & Masaki, T., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

30 Scopus citations

Polarized secretion of endothelin-1 and big ET-1 in MDCK cells is inhibited by cell Na+ flux and disrupted by NH4Cl

Uchida, S., Horie, M., Yanagisawa, M., Matsushita, Y., Kurokawa, K. & Ogata, E., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

15 Scopus citations

Possible role of endothelin in the pathogenesis of cerebral vasospasm

Shigeno, T., Mima, T., Yanagisawa, M., Saito, A., Fujimori, A., Shiba, R., Goto, K., Kimura, S., Yamashita, K., Yamasaki, Y., Masaki, T. & Takakura, K., 1991, In : Journal of Cardiovascular Pharmacology. 17, SUPPL. 7

Research output: Contribution to journalArticle

21 Scopus citations

Prevention of cerebral vasospasm by actinomycin D

Shigeno, T., Mima, T., Yanagisawa, M., Siato, A., Goto, K., Yamashita, K., Takenouchi, T., Matsuura, N., Yamasaki, Y., Yamada, K., Masaki, T. & Takakura, K., 1991, In : Journal of Neurosurgery. 74, 6, p. 940-943 4 p.

Research output: Contribution to journalArticle

36 Scopus citations

Role of endothelin in the development of dahl hypertension

Goligorsky, M. S., Iijima, K., Morgan, M., Yanagisawa, M., Masaki, T., Lin, L., Nasjletti, A., Kaskel, F., Frazer, M. & Badr, K. F., 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S484-S491

Research output: Contribution to journalArticle

25 Scopus citations

TaqI polymorphism at the human preproendothelin-1 gene (EDN1)

Watanabe, M., Yanagisawa, M., Hamaguchi, H., Kanazawa, I. & Masaki, T., Sep 25 1991, In : Nucleic Acids Research. 19, 18, p. 5099 1 p.

Research output: Contribution to journalArticle

3 Scopus citations

Topographical localisation of endothelin mRNA and peptide immunoreactivity in neurones of the human brain

Giaid, A., Gibson, S. J., Herrero, M. T., Gentleman, S., Legon, S., Yanagisawa, M., Masaki, T., Ibrahim, N. B. N., Roberts, G. W., Rossi, M. L. & Polak, J. M., Jan 1991, In : Histochemistry. 95, 3, p. 303-314 12 p.

Research output: Contribution to journalArticle

146 Scopus citations
1990

Affinity labelling of endothelin receptor and characterization of solubilized endothelin-endothelin-receptor complex

Miyazaki, H., Kondoh, M., Watanabe, H., Masuda, Y., Murakami, K., Takahashi, M., Yanagisawa, M., Kimura, S., Goto, K. & Masaki, T., 1990, In : European Journal of Biochemistry. 187, 1, p. 125-129 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Analysis of big endothelin-1 digestion by cathepsin D

Sawamura, T., Shinmi, O., Kishi, N., Sugita, Y., Yanagisawa, M., Goto, K., Masaki, T. & Kimura, S., Oct 30 1990, In : Biochemical and Biophysical Research Communications. 172, 2, p. 883-889 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cardiovascular effects of the endothelins

Masaki, T. & Yanagisawa, M., 1990, In : Cardiovascular Drug Reviews. 8, 4, p. 373-385 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cellular mechanism of vasoconstriction induced by endothelin.

Masaki, T., Yanagisawa, M., Takuwa, Y., Kasuya, Y., Kimura, S. & Goto, K., 1990, In : Advances in second messenger and phosphoprotein research. 24, p. 425-428 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Cerebral microvessel endothelium is producing endothelin

Yoshimoto, S., Ishizaki, Y., Kurihara, H., Sasaki, T., Yoshizumi, M., Yanagisawa, M., Yazaki, Y., Masaki, T., Takakura, K. & Murota, S. I., Feb 5 1990, In : Brain Research. 508, 2, p. 283-285 3 p.

Research output: Contribution to journalArticle

115 Scopus citations

Characterization of endothelin converting enzyme activities in soluble fraction of bovine cultured endothelial cells

Sawamura, T., Kimura, S., Shinmi, O., Sugita, Y., Kobayashi, M., Mitsui, Y., Yanagisawa, M., Goto, K. & Masaki, T., Jun 29 1990, In : Biochemical and Biophysical Research Communications. 169, 3, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

Sakurai, T., Yanagisawa, M., Takuwa, Y., Miyazaki, H., Kimura, S., Goto, K. & Masaki, T., Dec 20 1990, In : Nature. 348, 6303, p. 732-735 4 p.

Research output: Contribution to journalArticle

2288 Scopus citations

Detection of endothelin-1 in the human plasma and in the perfusate of rat mesenteric artery

Goto, K., Fujimori, A., Miyauchi, T., Ishikawa, T., Suzuki, N., Yanagisawa, M., Kimura, S. & Masaki, T., 1990, In : European Journal of Pharmacology. 183, 5, p. 1816-1817 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Detection of endothelin immunoreactivity and mRNA in pulmonary tumours

Giaid, A., Hamid, Q. A., Springall, D. R., Yanagisawa, M., Shinmi, O., Sawamura, T., Masaki, T., Kimura, S., Corrin, B. & Polak, J. M., 1990, In : Journal of Pathology. 162, 1, p. 15-22 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Distinct vascular and intestinal smooth muscle myosin heavy chain mRNAs are encoded by a single-copy gene in the chicken

Hamada, Y., Yanagisawa, M., Katsuragawa, Y., Coleman, J. R., Nagata, S., Matsuda, G. & Masaki, T., Jul 16 1990, In : Biochemical and Biophysical Research Communications. 170, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Effect of endothelin on cardiovascular system

Masaki, T., Yanagisawa, M., Kimura, S., Takuwa, Y. & Goto, K., 1990, In : Japanese Heart Journal. 31, 4, p. 517-518 2 p.

Research output: Contribution to journalArticle

Endothelin: A novel peptide in the posterior pituitary system

Yoshizawa, T., Shinmi, O., Giaid, A., Yanagisawa, M., Gibson, S. J., Kimura, S., Uchiyama, Y., Polak, J. M., Masaki, T. & Kanazawa, I., Jan 26 1990, In : Science. 247, 4941, p. 462-464 3 p.

Research output: Contribution to journalArticle

289 Scopus citations

Endothelin-induced vasoconstriction of cerebral and peripheral arteries of dogs

Saito, A., Mima, T., Shigeno, T., Yanagisawa, M., Goto, K., Kimura, S. & Masaki, T., 1990, In : European Journal of Pharmacology. 183, 5, p. 1803-1804 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Endothelin in plasma and cerebrospinal fluid of patients with subarachnoid haemorrhage

Fujimori, A., Yanagisawa, M., Saito, A., Goto, K., Masaki, T., Mima, T., Takakura, K. & Shigeno, T., Sep 8 1990, In : The Lancet. 336, 8715, p. 633 1 p.

Research output: Contribution to journalArticle

108 Scopus citations

Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells

Takuwa, Y., Kasuya, Y., Takuwa, N., Kudo, M., Yanagisawa, M., Goto, K., Masaki, T. & Yamashita, K., Mar 1990, In : Journal of Clinical Investigation. 85, 3, p. 653-658 6 p.

Research output: Contribution to journalArticle

158 Scopus citations

Increased maternal plasma concentration of endothelin-1 during labor pain or on delivery and the existence of a large amount of endothelin-1 in amniotic fluid

Usuki, S., Saitoh, T., Sawamura, T., Suzuki, N., Shigemitsu, S., Yanagisawa, M., Goto, K., Onda, H., Fujino, M. & Masaki, T., 1990, In : Gynecological Endocrinology. 4, 2, p. 85-97 13 p.

Research output: Contribution to journalArticle

54 Scopus citations

Interleukin 1 increases the production of endothelin-1 by cultured endothelial cells

Yoshizumi, M., Kurihara, H., Morita, T., Yamashita, T., Oh-hashi, Y., Sugiyama, T., Takaku, F., Yanagisawa, M., Masaki, T. & Yazaki, Y., Jan 15 1990, In : Biochemical and Biophysical Research Communications. 166, 1, p. 324-329 6 p.

Research output: Contribution to journalArticle

245 Scopus citations

Involvement of endothelin in the regulation of human vascular tonus - Potent vasoconstrictor effect and existence in endothelial cells

Miyauchi, T., Tomobe, Y., Shiba, R., Ishikawa, T., Yanagisawa, M., Kimura, S., Sugishita, Y., Ito, I., Goto, K. & Masaki, T., 1990, In : Circulation. 81, 6, p. 1874-1880 7 p.

Research output: Contribution to journalArticle

118 Scopus citations

Isolation of anti-endothelin receptor monoclonal antibodies for use in receptor characterization

Kondoh, M., Miyazaki, H., Watanabe, H., Shibata, T., Yanagisawa, M., Masaki, T. & Murakami, K., Oct 30 1990, In : Biochemical and Biophysical Research Communications. 172, 2, p. 503-510 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mechanisms of increased sensitivity to endothelin-1 in aorta from spontaneously hypertensive rats

Tomobe, Y., Ishikawa, T., Yanagisawa, M., Kimura, S., Masaki, T. & Goto, K., 1990, In : European Journal of Pharmacology. 183, 5, p. 1817 1 p.

Research output: Contribution to journalArticle

4 Scopus citations

Monoclonal antibodies to endothelin: Application for sandwich immunoassays

Hamaoki, M., Kato, H., Sugi, M., Fujimoto, M., Kurihara, H., Yosizumi, M., Yanagisawa, M., Kimura, S., Masaki, T. & Yazaki, Y., 1990, In : Hybridoma. 9, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Production of endothelin-1 by rat cultured mesangial cells

Sakamoto, H., Sasaki, S., Hirata, Y., Imai, T., Ando, K., Ida, T., Sakurai, T., Yanagisawa, M., Masaki, T. & Marumo, F., Jun 15 1990, In : Biochemical and Biophysical Research Communications. 169, 2, p. 462-468 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Purification and characterization of putative endothelin converting enzyme in bovine adrenal medulla: Evidence for a cathepsin D-like enzyme

Sawamura, T., Kimura, S., Shinmi, O., Sugita, Y., Yanagisawa, M., Goto, K. & Masaki, T., May 16 1990, In : Biochemical and Biophysical Research Communications. 168, 3, p. 1230-1236 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Role of endothelin in mechanisms of local blood pressure control

Masaki, T., Yanagisawa, M., Goto, K. & Kimura, S., 1990, In : Journal of Hypertension. 8, SUPPL. 7

Research output: Contribution to journalArticle

32 Scopus citations