• 72581 Citations
  • 120 h-Index
1984 …2020

Research output per year

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Research Output

1992

A pertussis toxin‐sensitive mechanism of endothelin action in porcine coronary artery smooth muscle

Kasuya, Y., Takuwa, Y., Yanagisawa, M., Masaki, T. & Goto, K., Oct 1992, In : British Journal of Pharmacology. 107, 2, p. 456-462 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Cardiovascular Effects of Endothelin

Goto, K., Yanagisawa, M., Kimura, S. & Masaki, T., Jan 1 1992, In : JAPANESE CIRCULATION JOURNAL. 56, 2, p. 162-169 8 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Complete primary structure and tissue expression of chicken pectoralis M- protein

Noguchi, J., Yanagisawa, M., Imamura, M., Kasuya, Y., Sakurai, T., Tanaka, T. & Masaki, T., Jan 1 1992, In : Journal of Biological Chemistry. 267, 28, p. 20302-20310 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Concomitant expression of receptor subtype and isopeptide of endothelin by human adrenal gland

Imai, T., Hirata, Y., Eguchi, S., Kanno, K., Ohta, K., Emori, T., Sakamoto, A., Yanagisawa, M., Masaki, T. & Marumo, F., Feb 14 1992, In : Biochemical and Biophysical Research Communications. 182, 3, p. 1115-1121 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Differential tissue expression of multiple genes for chicken smooth muscle/nonmuscle myosin regulatory light chains

Inoue, A., Yanagisawa, M. & Masaki, T., Mar 24 1992, In : BBA - Gene Structure and Expression. 1130, 2, p. 197-202 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Endothelin receptors in human parathyroid gland

Eguchi, S., Hirata, Y., Imai, T., Kanno, K., Akiba, T., Sakamoto, A., Yanagisawa, M., Masaki, T. & Marumo, F., May 15 1992, In : Biochemical and Biophysical Research Communications. 184, 3, p. 1448-1455 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Endothelins.

Masaki, T. & Yanagisawa, M., 1992, In : Essays in biochemistry. 27, p. 79-89 11 p.

Research output: Contribution to journalReview article

32 Scopus citations

Increased lung endothelin-1 production in rats with idiopathic pulmonary hypertension

Stelzner, T. J., O'Brien, R. F., Yanagisawa, M., Sakurai, T., Sato, K., Webb, S., Zamora, M., McMurtry, I. F. & Fisher, J. H., 1992, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 262, 5 6-5, p. L614-L620

Research output: Contribution to journalArticle

149 Scopus citations

Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells

Imai, T., Hirata, Y., Emori, T., Yanagisawa, M., Masaki, T. & Marumo, F., Jun 1992, In : Hypertension. 19, 6, p. 753-757 5 p.

Research output: Contribution to journalArticle

Open Access
329 Scopus citations

Interleukin-2 Suppresses Endothelin-1 Secretion of Cultured Endothelial Cells

Taniguchi, K., Morimoto, S., Fukuo, K., Ogihara, T., Yanagisawa, M., Masaki, T. & Suzuki, N., 1992, In : Hypertension Research. 15, p. 171-175 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Molecular characterization of endothelin receptors

Takeshi, S., Yanagisawa, M. & Tomoh, M., 1992, In : Trends in Pharmacological Sciences. 13, C, p. 103-108 6 p.

Research output: Contribution to journalReview article

598 Scopus citations

Physiology and pharmacology of endothelins

Masaki, T., Yanagisawa, M. & Goto, K., Jul 1992, In : Medicinal Research Reviews. 12, 4, p. 391-421 31 p.

Research output: Contribution to journalArticle

247 Scopus citations
1991

cDNA cloning, sequence analysis and tissue distribution of rat preproendothelin-1 mRNA

Sakurai, T., Yanagisawa, M., Inoue, A., Ryan, U. S., Kimura, S., Mitsui, Y., Goto, K. & Masaki, T., Feb 28 1991, In : Biochemical and Biophysical Research Communications. 175, 1, p. 44-47 4 p.

Research output: Contribution to journalArticle

233 Scopus citations

Characteristics of binding of endothelin-1 and endothelin-3 to rat hearts: Developmental changes in mechanical responses and receptor subtypes

Ishikawa, T., Li, L., Shinmi, O., Kimura, S., Yanagisawa, M., Goto, K. & Masaki, T., Jan 1 1991, In : Circulation research. 69, 4, p. 918-926 9 p.

Research output: Contribution to journalArticle

Open Access
50 Scopus citations

Characterization of the effect of endothelins in canine cerebral arteries

Saito, A., Shiba, R., Yanagisawa, M., Masaki, T., Kimura, S., Yamada, K., Mima, T., Shigeno, T. & Goto, K., 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S219-S221

Research output: Contribution to journalArticle

1 Scopus citations

Chromosomal assignments of the human endothelin family genes: The endothelin-1 gene (EDN1) to 6p23-p24, the endothelin-2 gene (EDN2) to 1p34, and the endothelin-3 gene (EDN3) to 20q13.2-q13.3

Arinami, T., Ishikawa, M., Inoue, A., Yanagisawa, M., Masaki, T., Yoshida, M. C. & Hamaguchi, H., May 22 1991, In : American Journal of Human Genetics. 48, 5, p. 990-996 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Cloning and functional expression of human cDNA for the ETB endothelin receptor

Sakamoto, A., Yanagisawa, M., Sakurai, T., Takuwa, Y., Yanagisawa, H. & Masaki, T., Jul 31 1991, In : Biochemical and Biophysical Research Communications. 178, 2, p. 656-663 8 p.

Research output: Contribution to journalArticle

241 Scopus citations

Comparison of endothelin-1 concentrations in normal and complicated pregnancies

Otani, S., Usuki, S., Saitoh, T., Yanagisawa, M., Iwasaki, H., Tanaka, J., Suzuki, N., Fujino, M., Goto, K. & Masaki, T., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S308-S312

Research output: Contribution to journalArticle

12 Scopus citations

Elevated plasma levels of endothelin‐1 in systemic sclerosis

Yamane, K., Kashiwagi, H., Suzuki, N., Miyauchi, T., Yanagisawa, M., Goto, K. & Masaki, T., Feb 1991, In : Arthritis & Rheumatism. 34, 2, p. 243-244 2 p.

Research output: Contribution to journalArticle

68 Scopus citations

Endothelin-1 in luteal tissue

Usuki, S., Suzuki, N., Matsumoto, H., Yanagisawa, M. & Masaki, T., Sep 1991, In : Molecular and Cellular Endocrinology. 80, 1-3, p. 147-151 5 p.

Research output: Contribution to journalArticle

37 Scopus citations

Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines

Shichiri, M., Hirata, Y., Nakajima, T., Ando, K., Imai, T., Yanagisawa, M., Masaki, T. & Marumo, F., May 1991, In : Journal of Clinical Investigation. 87, 5, p. 1867-1871 5 p.

Research output: Contribution to journalArticle

Open Access
195 Scopus citations

Endothelin induces DNA polymerase α activity in ovaries of hypophysectomized estrogen-treated immature rats

Usuki, S., Otani, S., Goto, K., Matsumoto, H., Suzuki, N., Yanagisawa, M. & Masaki, T., Jan 1 1991, In : Hormone and Metabolic Research. 23, 12, p. 621-622 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Endothelin in perinatal pharmacology

Masaki, T., Usuki, S., Yanagisawa, M. & Suzuki, N., Feb 1991, In : Seminars in Perinatology. 15, 1, p. 27-29 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Endothelins: vasoconstrictor effects and localization in canine cerebral arteries

Saito, A., Shiba, R., Yanagisawa, M., Masaki, T., Kimura, S., Yamada, K., Mima, T., Shigeno, T. & Goto, K., May 1991, In : British Journal of Pharmacology. 103, 1, p. 1129-1135 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Endothelin-secreting tumor

Yokokawa, K., Tahara, H., Kohno, M., Murakawa -i., K., Yasunari, K., Nakagawa, K., Hamada, T., Otani, S., Yanagisawa, M. & Takeda, T., 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S398-S41

Research output: Contribution to journalArticle

12 Scopus citations

Expression of endothelin-like peptide in the nervous system of the marine mollusk Aplysia

Giaid, A., Masaki, T., Ouimet, T., Yanagisawa, M., Gaspar, L., Cantin, M., Kimura, S. & Castellucci, V. F., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S449-S451

Research output: Contribution to journalArticle

9 Scopus citations

Hypertension associated with endothelin-secreting malignant hemangioendothelioma

Yokokawa, K., Tahara, H., Kohno, M., Murakawa, K. I., Yasunari, K., Nakagawa, K., Hamada, T., Otani, S., Yanagisawa, M. & Takeda, T., Jan 1 1991, In : Annals of internal medicine. 114, 3, p. 213-215 3 p.

Research output: Contribution to journalArticle

158 Scopus citations

Increased plasma concentrations of endothelin-1 during and after pulmonary surgery

Onizuka, M., Miyauchi, T., Morita, R., Akaogi, E., Mitsui, K., Suzuki, N., Fujino, M., Yanagisawa, M., Goto, K., Masaki, T. & Hori, M., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S402-S403

Research output: Contribution to journalArticle

10 Scopus citations

Increased plasma level of endothelin-1 and coronary spasm induction in patients with vasospastic angina pectoris

Toyo-oka, T., Aizawa, T., Suzuki, N., Hirata, Y., Miyauchi, T., Shin, W. S., Yanagisawa, M., Masaki, T. & Sugimoto, T., Jan 1 1991, In : Circulation. 83, 2, p. 476-483 8 p.

Research output: Contribution to journalArticle

Open Access
226 Scopus citations

Mechanisms of altered sensitivity to endothelin-1 between aortic smooth muscles of spontaneously hypertensive and Wistar-Kyoto rats

Tomobe, Y., Ishikawa, T., Yanagisawa, M., Kimura, S., Masaki, T. & Goto, K., Jan 1 1991, In : Journal of Pharmacology and Experimental Therapeutics. 257, 2, p. 555-561 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Mechanisms of endothelin-1 mRNA and peptides induction by TGF-β and TPA in MDCK cells

Horie, M., Uchida, S., Yanagisawa, M., Matsushita, Y., Kurokawa, K. & Ogata, E., 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S222-S225

Research output: Contribution to journalArticle

16 Scopus citations

Molecular and cellular mechanism of endothelin regulation: Implications for vascular function

Masaki, T., Kimura, S., Yanagisawa, M. & Goto, K., Oct 1991, In : Circulation. 84, 4, p. 1457-1468 12 p.

Research output: Contribution to journalArticle

Open Access
398 Scopus citations

Phosphoramidon inhibits the intracellular conversion of big endothelin-1 to endothelin-1 in cultured endothelial cells

Sawamura, T., Kasuya, Y., Matsushita, Y., Suzuki, N., Shinmi, O., Kishi, N., Sugita, Y., Yanagisawa, M., Goto, K., Masaki, T. & Kimura, S., Jan 31 1991, In : Biochemical and Biophysical Research Communications. 174, 2, p. 779-784 6 p.

Research output: Contribution to journalArticle

77 Scopus citations

Plasma concentrations of endothelin-1 and endothelin-3 are altered differently in various pathophysiological conditions in humans

Miyauchi, T., Sugishita, Y., Yamaguchi, I., Ajisaka, R., Tomizawa, T., Onizuka, M., Matsuda, M., Kono, I., Yanagisawa, M., Goto, K., Suzuki, N., Matsumoto, H. & Masaki, T., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S394-S397

Research output: Contribution to journalArticle

30 Scopus citations

Polarized secretion of endothelin-1 and big ET-1 in MDCK cells is inhibited by cell Na+flux and disrupted by NH4Cl

Uchida, S., Horie, M., Yanagisawa, M., Matsushita, Y., Kurokawa, K. & Ogata, E., 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S226-S228

Research output: Contribution to journalArticle

15 Scopus citations

Possible role of endothelin in the pathogenesis of cerebral vasospasm

Shigeno, T., Mima, T., Yanagisawa, M., Saito, A., Fujimori, A., Shiba, R., Goto, K., Kimura, S., Yamashita, K., Yamasaki, Y., Masaki, T. & Takakura, K., Jan 1 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S480-S483

Research output: Contribution to journalArticle

21 Scopus citations

Prevention of cerebral vasospasm by actinomycin D

Shigeno, T., Mima, T., Yanagisawa, M., Siato, A., Goto, K., Yamashita, K., Takenouchi, T., Matsuura, N., Yamasaki, Y., Yamada, K., Masaki, T. & Takakura, K., 1991, In : Journal of neurosurgery. 74, 6, p. 940-943 4 p.

Research output: Contribution to journalArticle

36 Scopus citations

Role of endothelin in the development of dahl hypertension

Goligorsky, M. S., Iijima, K., Morgan, M., Yanagisawa, M., Masaki, T., Lin, L., Nasjletti, A., Kaskel, F., Frazer, M. & Badr, K. F., 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S484-S491

Research output: Contribution to journalArticle

25 Scopus citations

TaqI polymorphism at the human preproendothelin-1 gene (EDN1)

Watanabe, M., Yanagisawa, M., Hamaguchi, H., Kanazawa, I. & Masaki, T., Sep 25 1991, In : Nucleic acids research. 19, 18, 1 p.

Research output: Contribution to journalArticle

3 Scopus citations

Topographical localisation of endothelin mRNA and peptide immunoreactivity in neurones of the human brain

Giaid, A., Gibson, S. J., Herrero, M. T., Gentleman, S., Legon, S., Yanagisawa, M., Masaki, T., Ibrahim, N. B. N., Roberts, G. W., Rossi, M. L. & Polak, J. M., Jan 1 1991, In : Histochemistry. 95, 3, p. 303-314 12 p.

Research output: Contribution to journalArticle

147 Scopus citations
1990

Affinity labelling of endothelin receptor and characterization of solubilized endothelin–endothelin‐receptor complex

Miyazaki, H., Kondoh, M., Watanabe, H., Masuda, Y., Murakami, K., Takahashi, M., Yanagisawa, M., Kimura, S., Goto, K. & Masaki, T., Jan 1990, In : European Journal of Biochemistry. 187, 1, p. 125-129 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Analysis of big endothelin-1 digestion by cathepsin D

Sawamura, T., Shinmi, O., Kishi, N., Sugita, Y., Yanagisawa, M., Goto, K., Masaki, T. & Kimura, S., Oct 30 1990, In : Biochemical and Biophysical Research Communications. 172, 2, p. 883-889 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cardiovascular Effects of the Endothelins

Masaki, T. & Yanagisawa, M., Dec 1990, In : Cardiovascular Drug Reviews. 8, 4, p. 373-385 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cellular mechanism of vasoconstriction induced by endothelin.

Masaki, T., Yanagisawa, M., Takuwa, Y., Kasuya, Y., Kimura, S. & Goto, K., 1990, In : Advances in Second Messenger and Phosphoprotein Research. 24, p. 425-428 4 p.

Research output: Contribution to journalReview article

8 Scopus citations

Cerebral microvessel endothelium is producing endothelin

Yoshimoto, S., Ishizaki, Y., Kurihara, H., Sasaki, T., Yoshizumi, M., Yanagisawa, M., Yazaki, Y., Masaki, T., Takakura, K. & Murota, S. I., Feb 5 1990, In : Brain Research. 508, 2, p. 283-285 3 p.

Research output: Contribution to journalArticle

116 Scopus citations

Characterization of endothelin converting enzyme activities in soluble fraction of bovine cultured endothelial cells

Sawamura, T., Kimura, S., Shinmi, O., Sugita, Y., Kobayashi, M., Mitsui, Y., Yanagisawa, M., Goto, K. & Masaki, T., Jun 29 1990, In : Biochemical and Biophysical Research Communications. 169, 3, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

Sakurai, T., Yanagisawa, M., Takuwa, Y., Miyazaki, H., Kimura, S., Goto, K. & Masaki, T., 1990, In : Nature. 348, 6303, p. 732-735 4 p.

Research output: Contribution to journalArticle

2296 Scopus citations

Detection of endothelin-1 in the human plasma and in the perfusate of rat mesenteric artery

Goto, K., Fujimori, A., Miyauchi, T., Ishikawa, T., Suzuki, N., Yanagisawa, M., Kimura, S. & Masaki, T., Jan 1 1990, In : European Journal of Pharmacology. 183, 5, p. 1816-1817 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Detection of endothelin immunoreactivity and mRNA in pulmonary tumours

Giaid, A., Hamid, Q. A., Springall, D. R., Yanagisawa, M., Shinmi, O., Sawamura, T., Masaki, T., Kimura, S., Corrin, B. & Polak, J. M., Sep 1990, In : The Journal of Pathology. 162, 1, p. 15-22 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Distinct vascular and intestinal smooth muscle myosin heavy chain mRNAs are encoded by a single-copy gene in the chicken

Hamada, Y., Yanagisawa, M., Katsuragawa, Y., Coleman, J. R., Nagata, S., Matsuda, G. & Masaki, T., Jul 16 1990, In : Biochemical and Biophysical Research Communications. 170, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

57 Scopus citations