• 71926 Citations
  • 119 h-Index
1984 …2020

Research output per year

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Research Output

2019

Effects of 3 Weeks of Water Immersion and Restraint Stress on Sleep in Mice

Yasugaki, S., Liu, C. Y., Kashiwagi, M., Kanuka, M., Honda, T., Miyata, S., Yanagisawa, M. & Hayashi, Y., Oct 14 2019, In : Frontiers in Neuroscience. 13, 1072.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Essential structure of orexin 1 receptor antagonist YNT-707, part III: Role of the 14-hydroxy and the 3-methoxy groups in antagonistic activity toward the orexin 1 receptor in YNT-707 derivatives lacking the 4,5-epoxy ring

Yamamoto, N., Ohrui, S., Okada, T., Saitoh, T., Kutsumura, N., Nagumo, Y., Irukayama-Tomobe, Y., Ogawa, Y., Ishikawa, Y., Watanabe, Y., Hayakawa, D., Gouda, H., Yanagisawa, M. & Nagase, H., Jan 1 2019, In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

2 Scopus citations

Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4,5-epoxymorphinan on the orexin 1 receptor antagonistic activity

Saitoh, T., Seki, K., Nakajima, R., Yamamoto, N., Kutsumura, N., Nagumo, Y., Irukayama-Tomobe, Y., Ogawa, Y., Ishikawa, Y., Tanimura, R., Yanagisawa, M. & Nagase, H., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

1 Scopus citations

Improvement of slow wave sleep continuity by mattresswith better body pressure dispersal

Kayaba, M., Ogata, H., Park, I., Ishihara, A., Kawana, F., Kokubo, T., Fukusumi, S., Hayashi, M., Tokuyama, K., Yanagisawa, M. & Satoh, M., Dec 1 2019, In : Sleep Medicine Research. 10, 2, p. 75-82 8 p.

Research output: Contribution to journalArticle

Open Access

MC-SleepNet: Large-scale Sleep Stage Scoring in Mice by Deep Neural Networks

Yamabe, M., Horie, K., Shiokawa, H., Funato, H., Yanagisawa, M. & Kitagawa, H., Dec 1 2019, In : Scientific reports. 9, 1, 15793.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Methodology and theoretical basis of forward genetic screening for sleep/wakefulness in mice

Miyoshi, C., Kim, S. J., Ezaki, T., Ikkyu, A., Hotta-Hirashima, N., Kanno, S., Kakizaki, M., Yamada, M., Wakana, S., Yanagisawa, M. & Funato, H., Aug 6 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 32, p. 16062-16067 6 p.

Research output: Contribution to journalArticle

Open Access

Sleep State Analysis Using Calcium Imaging Data by Non-negative Matrix Factorization

Nagayama, M., Aritake, T., Hino, H., Kanda, T., Miyazaki, T., Yanagisawa, M., Akaho, S. & Murata, N., Jan 1 2019, Artificial Neural Networks and Machine Learning – ICANN 2019: Theoretical Neural Computation - 28th International Conference on Artificial Neural Networks, 2019, Proceedings. Tetko, I. V., Karpov, P., Theis, F. & Kurková, V. (eds.). Springer Verlag, p. 102-113 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11727 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Toward the mysteries of sleep

Yanagisawa, M., Jan 1 2019, In : Keio Journal of Medicine. 68, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
2020

Copine-7 is required for REM sleep regulation following cage change or water immersion and restraint stress in mice

Liu, C. Y., Tsai, C. J., Yasugaki, S., Nagata, N., Morita, M., Isotani, A., Yanagisawa, M. & Hayashi, Y., Jan 1 2020, (Accepted/In press) In : Neuroscience Research.

Research output: Contribution to journalArticle

Enhanced cortical responsiveness during natural sleep in freely behaving mice

Matsumoto, S., Ohyama, K., Díaz, J., Yanagisawa, M., Greene, R. W. & Vogt, K. E., Dec 1 2020, In : Scientific reports. 10, 1, 2278.

Research output: Contribution to journalArticle

Open Access

Essential structure of orexin 1 receptor antagonist YNT-707, part V: Structure-activity relationship study of the substituents on the 17-amino group

Saitoh, T., Seki, K., Nakajima, R., Yamamoto, N., Kutsumura, N., Nagumo, Y., Irukayama-Tomobe, Y., Ogawa, Y., Ishikawa, Y., Yanagisawa, M. & Nagase, H., Feb 1 2020, In : Bioorganic and Medicinal Chemistry Letters. 30, 3, 126893.

Research output: Contribution to journalArticle

Widely Distributed Neurotensinergic Neurons in the Brainstem Regulate NREM Sleep in Mice

Kashiwagi, M., Kanuka, M., Tatsuzawa, C., Suzuki, H., Morita, M., Tanaka, K., Kawano, T., Shin, J. W., Suzuki, H., Itohara, S., Yanagisawa, M. & Hayashi, Y., Mar 23 2020, In : Current Biology. 30, 6, p. 1002-1010.e4

Research output: Contribution to journalArticle

2 Scopus citations

α-synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: A prodromal Parkinson's disease model

Taguchi, T., Ikuno, M., Hondo, M., Parajuli, L. K., Taguchi, K., Ueda, J., Sawamura, M., Okuda, S., Nakanishi, E., Hara, J., Uemura, N., Hatanaka, Y., Ayaki, T., Matsuzawa, S., Tanaka, M., El-Agnaf, O. M. A., Koike, M., Yanagisawa, M., Uemura, M. T., Yamakado, H. & 1 others, Takahashi, R., Jan 1 2020, In : Brain. 143, 1, p. 249-265 17 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations