• 765 Citations
  • 13 h-Index
20092020

Research output per year

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Research Output

  • 765 Citations
  • 13 h-Index
  • 20 Article
  • 1 Review article
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Article
2020

A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins

Theodoropoulos, P. C., Wang, W., Budhipramono, A., Thompson, B. M., Madhusudhan, N., Mitsche, M. A., McDonald, J. G., De Brabander, J. K. & Nijhawan, D., Apr 1 2020, In : Journal of the American Chemical Society. 142, 13, p. 6128-6138 11 p.

Research output: Contribution to journalArticle

Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression

Cardoso, A. C., Lam, N. T., Savla, J. J., Nakada, Y., Pereira, A. H. M., Elnwasany, A., Menendez-Montes, I., Ensley, E. L., Bezan Petric, U., Sharma, G., Sherry, A. D., Malloy, C. R., Khemtong, C., Kinter, M. T., Tan, W. L. W., Anene-Nzelu, C. G., Foo, R. S. Y., Nguyen, N. U. N., Li, S., Ahmed, M. S. & 14 others, Elhelaly, W. M., Abdisalaam, S., Asaithamby, A., Xing, C., Kanchwala, M., Vale, G., Eckert, K. M., Mitsche, M. A., McDonald, J. G., Hill, J. A., Huang, L., Shaul, P. W., Szweda, L. I. & Sadek, H. A., Feb 1 2020, In : Nature Metabolism. 2, 2, p. 167-178 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Insights into lipid accumulation in skeletal muscle in dysferlin-deficient mice

Agarwal, A. K., Tunison, K., Mitsche, M. A., McDonald, J. G. & Garg, A., 2019, In : Journal of lipid research. 60, 12, p. 2057-2073 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Three-phase liquid extraction: A simple and fast method for lipidomic workflows

Vale, G., Martin, S. A., Mitsche, M. A., Thompson, B. M., Eckert, K. M. & McDonald, J. G., Jan 1 2019, In : Journal of lipid research. 60, 3, p. 694-706 13 p.

Research output: Contribution to journalArticle

5 Scopus citations
2018
30 Scopus citations
2017

Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI

Zhang, Y., Udayakumar, D., Cai, L., Hu, Z., Kapur, P., Kho, E. Y., Pavía-Jiménez, A., Fulkerson, M., de Leon, A. D., Yuan, Q., Dimitrov, I. E., Yokoo, T., Ye, J., Mitsche, M. A., Kim, H., McDonald, J. G., Xi, Y., Madhuranthakam, A. J., Dwivedi, D. K., Lenkinski, R. E. & 5 others, Cadeddu, J. A., Margulis, V., Brugarolas, J., DeBerardinis, R. J. & Pedrosa, I., Aug 3 2017, In : JCI Insight. 2, 15

Research output: Contribution to journalArticle

Open Access
16 Scopus citations
2016

Contribution of accelerated degradation to feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol metabolism in the liver

Hwang, S., Hartman, I. Z., Calhoun, L. N., Garland, K., Young, G. A., Mitsche, M. A., McDonald, J., Xu, F., Engelking, L. & DeBose-Boyd, R. A., Jun 24 2016, In : Journal of Biological Chemistry. 291, 26, p. 13479-13494 16 p.

Research output: Contribution to journalArticle

19 Scopus citations

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis

Padanad, M. S., Konstantinidou, G., Venkateswaran, N., Melegari, M., Rindhe, S., Mitsche, M., Yang, C., Batten, K., Huffman, K. E., Liu, J., Tang, X., Rodriguez-Canales, J., Kalhor, N., Shay, J. W., Minna, J. D., McDonald, J., Wistuba, I. I., DeBerardinis, R. J. & Scaglioni, P. P., Aug 9 2016, In : Cell Reports. 16, 6, p. 1614-1628 15 p.

Research output: Contribution to journalArticle

51 Scopus citations

Transcription factor hepatocyte nuclear factor-1β regulates renal cholesterol metabolism

Aboudehen, K., Kim, M. S., Mitsche, M., Garland, K., Anderson, N., Noureddine, L., Pontoglio, M., Patel, V., Xie, Y., Debose-Boyd, R. & Igarashi, P., Aug 2016, In : Journal of the American Society of Nephrology. 27, 8, p. 2408-2421 14 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling

Lin, R., Elf, S., Shan, C., Kang, H. B., Ji, Q., Zhou, L., Hitosugi, T., Zhang, L., Zhang, S., Seo, J. H., Xie, J., Tucker, M., Gu, T. L., Sudderth, J., Jiang, L., Mitsche, M., DeBerardinis, R. J., Wu, S., Li, Y., Mao, H. & 17 others, Chen, P. R., Wang, D., Chen, G. Z., Hurwitz, S. J., Lonial, S., Arellano, M. L., Khoury, H. J., Khuri, F. R., Lee, B. H., Lei, Q., Brat, D. J., Ye, K., Boggon, T. J., He, C., Kang, S., Fan, J. & Chen, J., Nov 1 2015, In : Nature cell biology. 17, 11, p. 1484-1496 13 p.

Research output: Contribution to journalArticle

96 Scopus citations

Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance

Moon, Y. A., Ochoa, C. R., Mitsche, M. A., Hammer, R. E. & Horton, J. D., Jan 1 2015, In : Journal of lipid research. 55, 12, p. 2597-2605 9 p., A16.

Research output: Contribution to journalArticle

37 Scopus citations

Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways

Mitsche, M. A., McDonald, J. G., Hobbs, H. H. & Cohen, J. C., Jun 26 2015, In : eLife. 4, JUNE 2015, p. 1-21 21 p., e07999.

Research output: Contribution to journalArticle

48 Scopus citations

Relative roles of ABCG5/ABCG8 in liver and intestine

Wang, J., Mitsche, M. A., Lütjohann, D., Cohen, J. C., Xie, X. S. & Hobbs, H. H., Feb 1 2015, In : Journal of lipid research. 56, 2, p. 319-330 12 p.

Research output: Contribution to journalArticle

67 Scopus citations

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition

Gao, L., Rabbitt, E. H., Condon, J. C., Renthal, N. E., Johnston, J. M., Mitsche, M. A., Chambon, P., Xu, J., O'Malley, B. W. & Mendelson, C. R., Jul 1 2015, In : Journal of Clinical Investigation. 125, 7, p. 2808-2824 17 p.

Research output: Contribution to journalArticle

38 Scopus citations
2014

Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport

Yang, C., Ko, B., Hensley, C. T., Jiang, L., Wasti, A. T., Kim, J., Sudderth, J., Calvaruso, M., Lumata, L., Mitsche, M., Rutter, J., Merritt, M. E. & DeBerardinis, R. J., Jan 1 2014, In : Molecular cell. 56, 3, p. 414-424 11 p.

Research output: Contribution to journalArticle

243 Scopus citations

Surface tensiometry of apolipoprotein B Domains at lipid interfaces suggests a new model for the initial steps in triglyceride-rich lipoprotein assembly

Mitsche, M. A., Packer, L. E., Brown, J. W., Jiang, Z. G., Small, D. M. & McKnight, C. J., Mar 30 2014, In : Journal of Biological Chemistry. 289, 13, p. 9000-9012 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013

Surface pressure-dependent conformation change of apolipoprotein-derived amphipathic α-helices

Mitsche, M. A. & Small, D. M., Jun 1 2013, In : Journal of lipid research. 54, 6, p. 1578-1588 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011
15 Scopus citations
2010
32 Scopus citations
2009

Interfacial properties of a complex multi-domain 490 amino acid peptide derived from apolipoprotein B (residues 292-782)

Mitsche, M. A., Wang, L., Jiang, Z. G., McKnight, C. J. & Small, D. M., Feb 17 2009, In : Langmuir. 25, 4, p. 2322-2330 9 p.

Research output: Contribution to journalArticle

11 Scopus citations