• 644 Citations
  • 13 h-Index
20092019
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Research Output 2009 2019

  • 644 Citations
  • 13 h-Index
  • 17 Article
  • 1 Review article
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Article
2019
2 Citations (Scopus)

Three-phase liquid extraction: A simple and fast method for lipidomic workflows

Dias do Vale, G., Martin, S. A., Mitsche, M. A., Thompson, B. M., Eckert, K. M. & McDonald, J. G., Jan 1 2019, In : Journal of lipid research. 60, 3, p. 694-706 13 p.

Research output: Contribution to journalArticle

Liquid-Liquid Extraction
Workflow
Lipids
Liquids
Liver
2018
16 Citations (Scopus)
Essential Fatty Acids
Phospholipases
Phospholipids
Triglycerides
Lipids
2017
15 Citations (Scopus)

Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI

Zhang, Y., Udayakumar, D., Cai, L., Hu, Z., Kapur, P., Kho, E. Y., Pavía-Jiménez, A., Fulkerson, M., de Leon, A. D., Yuan, Q., Dimitrov, I. E., Yokoo, T., Ye, J., Mitsche, M. A., Kim, H., McDonald, J. G., Xi, Y., Madhuranthakam, A. J., Dwivedi, D. K., Lenkinski, R. E. & 5 others, Cadeddu, J. A., Margulis, V., Brugarolas, J., DeBerardinis, R. J. & Pedrosa, I., Aug 3 2017, In : JCI insight. 2, 15

Research output: Contribution to journalArticle

Open Access
Renal Cell Carcinoma
Neoplasms
Fats
Lipids
Lipid Metabolism
2016
16 Citations (Scopus)

Contribution of accelerated degradation to feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol metabolism in the liver

Hwang, S., Hartman, I. Z., Calhoun, L. N., Garland, K., Young, G. A., Mitsche, M. A., McDonald, J., Xu, F., Engelking, L. & DeBose-Boyd, R. A., Jun 24 2016, In : Journal of Biological Chemistry. 291, 26, p. 13479-13494 16 p.

Research output: Contribution to journalArticle

Metabolism
Coenzyme A
Liver
Oxidoreductases
Feedback
8 Citations (Scopus)

Transcription factor hepatocyte nuclear factor-1β regulates renal cholesterol metabolism

Aboudehen, K., Kim, M. S., Mitsche, M., Garland, K., Anderson, N., Noureddine, L., Pontoglio, M., Patel, V., Xie, Y., Debose-Boyd, R. & Igarashi, P., Aug 1 2016, In : Journal of the American Society of Nephrology. 27, 8, p. 2408-2421 14 p.

Research output: Contribution to journalArticle

Hepatocyte Nuclear Factor 1
Cholesterol
Kidney
Sterols
Hydroxymethylglutaryl CoA Reductases
2015
79 Citations (Scopus)

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling

Lin, R., Elf, S., Shan, C., Kang, H. B., Ji, Q., Zhou, L., Hitosugi, T., Zhang, L., Zhang, S., Seo, J. H., Xie, J., Tucker, M., Gu, T. L., Sudderth, J., Jiang, L., Mitsche, M., DeBerardinis, R. J., Wu, S., Li, Y., Mao, H. & 17 others, Chen, P. R., Wang, D., Chen, G. Z., Hurwitz, S. J., Lonial, S., Arellano, M. L., Khoury, H. J., Khuri, F. R., Lee, B. H., Lei, Q., Brat, D. J., Ye, K., Boggon, T. J., He, C., Kang, S., Fan, J. & Chen, J., Nov 1 2015, In : Nature Cell Biology. 17, 11, p. 1484-1496 13 p.

Research output: Contribution to journalArticle

Phosphogluconate Dehydrogenase
Pentose Phosphate Pathway
Lipogenesis
AMP-Activated Protein Kinases
Growth
32 Citations (Scopus)

Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance

Moon, Y. A., Ochoa, C. R., Mitsche, M. A., Hammer, R. E. & Horton, J. D., Jan 1 2015, In : Journal of Lipid Research. 55, 12, p. 2597-2605 9 p., A16.

Research output: Contribution to journalArticle

Fatty Liver
Oleic Acid
Liver
Insulin Resistance
Fatty Acids
40 Citations (Scopus)

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis

Padanad, M. S., Konstantinidou, G., Venkateswaran, N., Melegari, M., Rindhe, S., Mitsche, M., Yang, C., Batten, K., Huffman, K. E., Liu, J., Tang, X., Rodriguez-Canales, J., Kalhor, N., Shay, J. W., Minna, J. D., McDonald, J., Wistuba, I. I., DeBerardinis, R. J. & Scaglioni, P. P., Dec 29 2015, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

Coenzyme A Ligases
Lung Neoplasms
Carcinogenesis
Fatty Acids
Cells
41 Citations (Scopus)

Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways

Mitsche, M. A., McDonald, J. G., Hobbs, H. H. & Cohen, J. C., Jun 26 2015, In : eLife. 4, JUNE 2015, p. 1-21 21 p., e07999.

Research output: Contribution to journalArticle

Biosynthesis
Sterols
Cholesterol
Tissue
Fluxes
58 Citations (Scopus)

Relative roles of ABCG5/ABCG8 in liver and intestine

Wang, J., Mitsche, M. A., Lütjohann, D., Cohen, J. C., Xie, X. S. & Hobbs, H. H., Feb 1 2015, In : Journal of Lipid Research. 56, 2, p. 319-330 12 p.

Research output: Contribution to journalArticle

Sterols
Liver
Intestines
Cholesterol
Phytosterols
32 Citations (Scopus)

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition

Gao, L., Rabbitt, E. H., Condon, J. C., Renthal, N. E., Johnston, J. M., Mitsche, M. A., Chambon, P., Xu, J., O'Malley, B. W. & Mendelson, C. R., Jul 1 2015, In : Journal of Clinical Investigation. 125, 7, p. 2808-2824 17 p.

Research output: Contribution to journalArticle

Nuclear Receptor Coactivator 2
Nuclear Receptor Coactivator 1
Pulmonary Surfactant-Associated Protein A
Mothers
Parturition
2014
206 Citations (Scopus)

Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport

Yang, C., Ko, B., Hensley, C. T., Jiang, L., Wasti, A. T., Kim, J., Sudderth, J., Calvaruso, M., Lumata, L., Mitsche, M., Rutter, J., Merritt, M. E. & DeBerardinis, R. J., 2014, In : Molecular Cell. 56, 3, p. 414-424 11 p.

Research output: Contribution to journalArticle

Glutamate Dehydrogenase
Citric Acid Cycle
Glutamine
Pyruvic Acid
Cell Survival
6 Citations (Scopus)

Surface tensiometry of apolipoprotein B Domains at lipid interfaces suggests a new model for the initial steps in triglyceride-rich lipoprotein assembly

Mitsche, M. A., Packer, L. E., Brown, J. W., Jiang, Z. G., Small, D. M. & McKnight, C. J., Mar 30 2014, In : Journal of Biological Chemistry. 289, 13, p. 9000-9012 13 p.

Research output: Contribution to journalArticle

Triolein
Apolipoproteins B
Lipoproteins
Triglycerides
Lipids
2013
10 Citations (Scopus)

Surface pressure-dependent conformation change of apolipoprotein-derived amphipathic α-helices

Mitsche, M. A. & Small, D. M., Jun 1 2013, In : Journal of Lipid Research. 54, 6, p. 1578-1588 11 p.

Research output: Contribution to journalArticle

Apolipoproteins
Triolein
Lipoproteins
Conformations
Pressure
2011
15 Citations (Scopus)
Pre-beta High-Density Lipoprotein
Triolein
Apolipoprotein A-I
Phospholipids
Water
2010
30 Citations (Scopus)
phase rule
Triolein
eggs
Phospholipids
surface water
2009
10 Citations (Scopus)

Interfacial properties of a complex multi-domain 490 amino acid peptide derived from apolipoprotein B (residues 292-782)

Mitsche, M. A., Wang, L., Jiang, Z. G., McKnight, C. J. & Small, D. M., Feb 17 2009, In : Langmuir. 25, 4, p. 2322-2330 9 p.

Research output: Contribution to journalArticle

Apolipoproteins B
Peptides
peptides
amino acids
Amino acids