• 9763 Citations
  • 50 h-Index
1979 …2018
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Fingerprint Dive into the research topics where Michael G Roth is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 23 Similar Profiles
Hemagglutinins Medicine & Life Sciences
Orthomyxoviridae Medicine & Life Sciences
Membranes Medicine & Life Sciences
Viruses Chemical Compounds
Proteins Medicine & Life Sciences
ADP-Ribosylation Factors Medicine & Life Sciences
Phospholipase D Medicine & Life Sciences
Madin Darby Canine Kidney Cells Medicine & Life Sciences

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Research Output 1979 2018

  • 9763 Citations
  • 50 h-Index
  • 114 Article
  • 1 Review article
13 Citations (Scopus)

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

McMillan, E. A., Ryu, M. J., Diep, C. H., Mendiratta, S., Clemenceau, J. R., Vaden, R. M., Kim, J. H., Motoyaji, T., Covington, K. R., Peyton, M., Huffman, K., Wu, X., Girard, L., Sung, Y., Chen, P. H., Mallipeddi, P. L., Lee, J. Y., Hanson, J., Voruganti, S., Yu, Y. & 20 others, Park, S., Sudderth, J., DeSevo, C., Muzny, D. M., Doddapaneni, H. V., Gazdar, A., Gibbs, R. A., Hwang, T. H., Heymach, J. V., Wistuba, I., Coombes, K. R., Williams, N. S., Wheeler, D. A., MacMillan, J. B., Deberardinis, R. J., Roth, M. G., Posner, B. A., Minna, J. D., Kim, H. S. & White, M. A., May 3 2018, In : Cell. 173, 4, p. 864-878.e29

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasms
Oncology
Biosynthesis
Small Molecule Libraries
9 Citations (Scopus)

Dapagliflozin suppresses glucagon signaling in rodent models of diabetes

Wang, M-Y., Yu, X., Lee, Y. H., McCorkle, S. K., Chen, S., Li, J., Wang, Z., Davidson, J. A., Scherer, P. E., Holland, W. L., Unger, R. H. & Roth, M. G., Jun 20 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 25, p. 6611-6616 6 p.

Research output: Contribution to journalArticle

Glucagon
Rodentia
Sodium-Glucose Transport Proteins
Liver
Glucose
20 Citations (Scopus)

SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

Tagal, V., Wei, S., Zhang, W., Brekken, R. A., Posner, B. A., Peyton, M., Girard, L., Hwang, T., Wheeler, D. A., Minna, J. D., White, M. A., Gazdar, A. F. & Roth, M. G., Jan 19 2017, In : Nature Communications. 8, 14098.

Research output: Contribution to journalArticle

Aurora Kinase A
mutations
Non-Small Cell Lung Carcinoma
lungs
inhibitors
4 Citations (Scopus)

An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon Production

Evans, M. R., Wei, S., Posner, B. A., Unger, R. H. & Roth, M. G., Apr 1 2016, In : Journal of Biomolecular Screening. 21, 4, p. 325-332 8 p.

Research output: Contribution to journalArticle

Glucagon
Assays
Medical problems
Glucagon Receptors
Insulin
4 Citations (Scopus)

A novel inhibitor of topoisomerase i is selectively toxic for a subset of non-small cell lung cancer cell lines

Zubovych, I. O., Sethi, A., Kulkarni, A., Tagal, V. & Roth, M. G., Jan 1 2016, In : Molecular Cancer Therapeutics. 15, 1, p. 23-36 14 p.

Research output: Contribution to journalArticle

Topoisomerase Inhibitors
Poisons
Non-Small Cell Lung Carcinoma
Cell Line
Camptothecin