• 4221 Citations
  • 23 h-Index
20072019

Research output per year

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Research Output

  • 4221 Citations
  • 23 h-Index
  • 27 Article
  • 1 Conference contribution
  • 1 Comment/debate
2019

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access

Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans

Ni, M., Solmonson, A., Pan, C., Yang, C., Li, D., Notzon, A., Cai, L., Guevara, G., Zacharias, L. G., Faubert, B., Vu, H. S., Jiang, L., Ko, B., Morales, N. M., Pei, J., Vale, G., Rakheja, D., Grishin, N. V., McDonald, J. G., Gotway, G. K. & 3 others, McNutt, M. C., Pascual, J. M. & DeBerardinis, R. J., Apr 30 2019, In : Cell Reports. 27, 5, p. 1376-1386.e6

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation

Gu, Z., Liu, Y., Cai, F., Patrick, M., Zmajkovic, J., Cao, H., Zhang, Y., Tasdogan, A., Chen, M., Qi, L., Liu, X., Li, K., Lyu, J., Dickerson, K. E., Chen, W., Ni, M., Merritt, M. E., Morrison, S. J., Skoda, R. C., DeBerardinis, R. J. & 1 others, Xu, J., Sep 1 2019, In : Cancer discovery. 9, 9, p. 1228-1247 20 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Gain-of-function variants in the ODC1 gene cause a syndromic neurodevelopmental disorder associated with macrocephaly, alopecia, dysmorphic features, and neuroimaging abnormalities

Rodan, L. H., Anyane-Yeboa, K., Chong, K., Klein Wassink-Ruiter, J. S., Wilson, A., Smith, L., Kothare, S. V., Rajabi, F., Blaser, S., Ni, M., DeBerardinis, R. J., Poduri, A. & Berry, G. T., Jan 1 2018, (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

3 Scopus citations

Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers

Huang, F., Ni, M., Chalishazar, M. D., Huffman, K. E., Kim, J., Cai, L., Shi, X., Cai, F., Zacharias, L. G., Ireland, A. S., Li, K., Gu, W., Kaushik, A. K., Liu, X., Gazdar, A. F., Oliver, T. G., Minna, J. D., Hu, Z. & DeBerardinis, R. J., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

17 Scopus citations
2017

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & Deberardinis, R. J., Jun 1 2017, In : Nature. 546, 7656, p. 168-172 5 p.

Research output: Contribution to journalArticle

56 Scopus citations

In Situ Capture of Chromatin Interactions by Biotinylated dCas9

Liu, X., Zhang, Y., Chen, Y., Li, M., Zhou, F., Li, K., Cao, H., Ni, M., Liu, Y., Gu, Z., Dickerson, K. E., Xie, S., Hon, G. C., Xuan, Z., Zhang, M. Q., Shao, Z. & Xu, J., Aug 24 2017, In : Cell. 170, 5, p. 1028-1043.e19

Research output: Contribution to journalArticle

64 Scopus citations

Lactate Metabolism in Human Lung Tumors

Faubert, B., Li, K. Y., Cai, L., Hensley, C. T., Kim, J., Zacharias, L. G., Yang, C., Do, Q. N., Doucette, S., Burguete, D., Li, H., Huet, G., Yuan, Q., Wigal, T., Butt, Y., Ni, M., Torrealba, J., Oliver, D., Lenkinski, R. E., Malloy, C. R. & 4 others, Wachsmann, J. W., Young, J. D., Kernstine, K. & DeBerardinis, R. J., Oct 5 2017, In : Cell. 171, 2, p. 358-371.e9

Research output: Contribution to journalArticle

200 Scopus citations

Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation

Liu, X., Zhang, Y., Ni, M., Cao, H., Signer, R. A. J., Li, D., Li, M., Gu, Z., Hu, Z., Dickerson, K. E., Weinberg, S. E., Chandel, N. S., Deberardinis, R. J., Zhou, F., Shao, Z. & Xu, J., May 31 2017, In : Nature Cell Biology. 19, 6, p. 626-638 13 p.

Research output: Contribution to journalArticle

36 Scopus citations
2016

Metabolic Heterogeneity in Human Lung Tumors

Hensley, C. T., Faubert, B., Yuan, Q., Lev-Cohain, N., Jin, E., Kim, J., Jiang, L., Ko, B., Skelton, R., Loudat, L., Wodzak, M., Klimko, C., McMillan, E., Butt, Y., Ni, M., Oliver, D., Torrealba, J., Malloy, C. R., Kernstine, K., Lenkinski, R. E. & 1 others, DeBerardinis, R. J., Feb 11 2016, In : Cell. 164, 4, p. 681-694 14 p.

Research output: Contribution to journalArticle

311 Scopus citations

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

Shu, S., Lin, C. Y., He, H. H., Witwicki, R. M., Tabassum, D. P., Roberts, J. M., Janiszewska, M., Huh, S. J., Liang, Y., Ryan, J., Doherty, E., Mohammed, H., Guo, H., Stover, D. G., Ekram, M. B., Peluffo, G., Brown, J., D'Santos, C., Krop, I. E., Dillon, D. & 20 others, McKeown, M., Ott, C., Qi, J., Ni, M., Rao, P. K., Duarte, M., Wu, S. Y., Chiang, C. M., Anders, L., Young, R. A., Winer, E. P., Letai, A., Barry, W. T., Carroll, J. S., Long, H. W., Brown, M., Liu, X. S., Meyer, C. A., Bradner, J. E. & Polyak, K., Jan 21 2016, In : Nature. 529, 7586, p. 413-417 5 p.

Research output: Contribution to journalArticle

217 Scopus citations
2014

Importance of breast cancer subtype in the development of androgen-receptor-directed therapy

Lim, E., Ni, M., Cao, S., Hazra, A., Tamimi, R. M. & Brown, M., 2014, In : Current Breast Cancer Reports. 6, 2, p. 71-78 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

Chen, X., Iliopoulos, D., Zhang, Q., Tang, Q., Greenblatt, M. B., Hatziapostolou, M., Lim, E., Tam, W. L., Ni, M., Chen, Y., Mai, J., Shen, H., Hu, D. Z., Adoro, S., Hu, B., Song, M., Tan, C., Landis, M. D., Ferrari, M., Shin, S. J. & 4 others, Brown, M., Chang, J. C., Liu, X. S. & Glimcher, L. H., 2014, In : Nature. 508, 1, p. 103-107 5 p.

Research output: Contribution to journalArticle

345 Scopus citations
2013

Amplitude modulation of androgen signaling by c-MYC

Ni, M., Chen, Y., Fei, T., Li, D., Lim, E., Liu, X. S. & Brown, M., Apr 1 2013, In : Genes and Development. 27, 7, p. 734-748 15 p.

Research output: Contribution to journalArticle

54 Scopus citations
2012

Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis andAKT oncogenic signaling

Wey, S., Luo, B., Tseng, C. C., Ni, M., Zhou, H., Fu, Y., Bhojwani, D., Carroll, W. L. & Lee, A. S., Jan 19 2012, In : Blood. 119, 3, p. 817-825 9 p.

Research output: Contribution to journalArticle

54 Scopus citations
2011

Beyond the endoplasmic reticulum: Atypical GRP78 in cell viability, signalling and therapeutic targeting

Ni, M., Zhang, Y. & Lee, A. S., Mar 1 2011, In : Biochemical Journal. 434, 2, p. 181-188 8 p.

Research output: Contribution to journalArticle

276 Scopus citations

Inositol 1,4,5-trisphosphate receptor 1 mutation perturbs glucose homeostasis and enhances susceptibility to diet-induced diabetes

Ye, R., Ni, M., Wang, M., Luo, S., Zhu, G., Chow, R. H. & Lee, A. S., Aug 2011, In : Journal of Endocrinology. 210, 2, p. 209-217 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B

Baba, A., Ohtake, F., Okuno, Y., Yokota, K., Okada, M., Imai, Y., Ni, M., Meyer, C. A., Igarashi, K., Kanno, J., Brown, M. & Kato, S., Jun 2011, In : Nature Cell Biology. 13, 6, p. 668-675 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

Targeting Androgen Receptor in Estrogen Receptor-Negative Breast Cancer

Ni, M., Chen, Y., Lim, E., Wimberly, H., Bailey, S. T., Imai, Y., Rimm, D. L., Shirley Liu, X. & Brown, M., Jul 12 2011, In : Cancer Cell. 20, 1, p. 119-131 13 p.

Research output: Contribution to journalArticle

220 Scopus citations
2010

Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP

Zhang, Y., Liu, R., Ni, M., Gill, P. & Lee, A. S., May 14 2010, In : Journal of Biological Chemistry. 285, 20, p. 15065-15075 11 p.

Research output: Contribution to journalArticle

177 Scopus citations

Nucleosome dynamics define transcriptional enhancers

He, H. H., Meyer, C. A., Shin, H., Bailey, S. T., Wei, G., Wang, Q., Zhang, Y., Xu, K., Ni, M., Lupien, M., Mieczkowski, P., Lieb, J. D., Zhao, K., Brown, M. & Liu, X. S., Apr 2010, In : Nature Genetics. 42, 4, p. 343-347 5 p.

Research output: Contribution to journalArticle

325 Scopus citations

Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6

Xu, J., Sankaran, V. G., Ni, M., Menne, T. F., Puram, R. V., Kim, W. & Orkin, S. H., Apr 15 2010, In : Genes and Development. 24, 8, p. 783-789 7 p.

Research output: Contribution to journalArticle

211 Scopus citations
2009

Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase

Zhang, Q., Gu, J., Li, L., Liu, J., Luo, B., Cheung, H. W., Boehm, J. S., Ni, M., Geisen, C., Root, D. E., Polyak, K., Brown, M., Richardson, A. L., Hahn, W. C., Kaelin, W. G. & Bommi-Reddy, A., Nov 6 2009, In : Cancer Cell. 16, 5, p. 413-424 12 p.

Research output: Contribution to journalArticle

87 Scopus citations

Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP

Ni, M., Zhou, H., Wey, S., Baumeister, P. & Lee, A. S., Aug 31 2009, In : PLoS One. 4, 8, e6868.

Research output: Contribution to journalArticle

100 Scopus citations
2008

Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development

Dong, D., Ni, M., Li, J., Xiong, S., Ye, W., Virrey, J. J., Mao, C., Ye, R., Wang, M., Pen, L., Dubeau, L., Groshen, S., Hofman, F. M. & Lee, A. S., Jan 15 2008, In : Cancer Research. 68, 2, p. 498-505 8 p.

Research output: Contribution to journalArticle

276 Scopus citations

Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells

Virrey, J. J., Dong, D., Stiles, C., Patterson, J. B., Pen, L., Ni, M., Schönthal, A. H., Chen, T. C., Hofman, F. M. & Lee, A. S., Aug 1 2008, In : Molecular Cancer Research. 6, 8, p. 1268-1275 8 p.

Research output: Contribution to journalArticle

111 Scopus citations

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

Li, J., Ni, M., Lee, B., Barron, E., Hinton, D. R. & Lee, A. S., 2008, In : Cell Death and Differentiation. 15, 9, p. 1460-1471 12 p.

Research output: Contribution to journalArticle

282 Scopus citations
2007

Endoplasmic reticulum stress

Bánhegyi, G., Baumeister, P., Benedetti, A., Dong, D., Fu, Y., Lee, A. S., Li, J., Mao, C., Margittai, É., Ni, M., Paschen, W., Piccirella, S., Senesi, S., Sitia, R., Wang, M. & Yang, W., Oct 2007, Annals of the New York Academy of Sciences. Vol. 1113. p. 58-71 14 p. (Annals of the New York Academy of Sciences; vol. 1113).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

99 Scopus citations

ER chaperones in mammalian development and human diseases

Ni, M. & Lee, A. S., Jul 31 2007, In : FEBS Letters. 581, 19, p. 3641-3651 11 p.

Research output: Contribution to journalArticle

560 Scopus citations