Patrick J Leavey

  • 1054 Citations
  • 17 h-Index
1989 …2019

Research output per year

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Research Output

  • 1054 Citations
  • 17 h-Index
  • 44 Article
  • 4 Review article
  • 2 Conference contribution
  • 2 Comment/debate
2019

Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group (British Journal of Cancer, (2018), 119, 5, (615-621), 10.1038/s41416-018-0212-9)

Shulman, D. S., Klega, K., Imamovic-Tuco, A., Clapp, A., Nag, A., Thorner, A. R., Van Allen, E., Ha, G., Lessnick, S. L., Gorlick, R., Janeway, K. A., Leavey, P. J., Mascarenhas, L., London, W. B., Vo, K. T., Stegmaier, K., Hall, D., Krailo, M. D., Barkauskas, D. A., DuBois, S. G. & 1 others, Crompton, B. D., Jan 1 2019, In : British Journal of Cancer.

Research output: Contribution to journalComment/debate

Open Access

Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib

Hassan, M., Butler, E., Wilson, R., Roy, A., Zheng, Y., Liem, P., Rakheja, D., Pavlick, D., Young, L. L., Rosenzweig, M., Erlich, R., Ali, S. M., Leavey, P. J., Parsons, D. W., Skapek, S. X. & Laetsch, T. W., Oct 1 2019, In : Cold Spring Harbor Molecular Case Studies. 5, 5

Research output: Contribution to journalArticle

Open Access

Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort

Smeland, S., Bielack, S. S., Whelan, J., Bernstein, M., Hogendoorn, P., Krailo, M. D., Gorlick, R., Janeway, K. A., Ingleby, F. C., Anninga, J., Antal, I., Arndt, C., Brown, K. L. B., Butterfass-Bahloul, T., Calaminus, G., Capra, M., Dhooge, C., Eriksson, M., Flanagan, A. M., Friedel, G. & 32 others, Gebhardt, M. C., Gelderblom, H., Goldsby, R., Grier, H. E., Grimer, R., Hawkins, D. S., Hecker-Nolting, S., Sundby Hall, K., Isakoff, M. S., Jovic, G., Kühne, T., Kager, L., von Kalle, T., Kabickova, E., Lang, S., Lau, C. C., Leavey, P. J., Lessnick, S. L., Mascarenhas, L., Mayer-Steinacker, R., Meyers, P. A., Nagarajan, R., Randall, R. L., Reichardt, P., Renard, M., Rechnitzer, C., Schwartz, C. L., Strauss, S., Teot, L., Timmermann, B., Sydes, M. R. & Marina, N., Mar 1 2019, In : European Journal of Cancer. 109, p. 36-50 15 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Viable and necrotic tumor assessment from whole slide images of osteosarcoma using machine-learning and deep-learning models

Arunachalam, H. B., Mishra, R., Daescu, O., Cederberg, K. B., Rakheja, D., Sengupta, A. L., Leonard, D., Hallac, R. R. & Leavey, P. J., Apr 1 2019, In : PloS one. 14, 4, e0210706.

Research output: Contribution to journalArticle

Open Access
2018

Convolutional neural network for histopathological analysis of osteosarcoma

Mishra, R., Daescu, O., Leavey, P., Rakheja, D. & Sengupta, A., Mar 1 2018, In : Journal of Computational Biology. 25, 3, p. 313-325 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Current Status and Future Perspectives on Neoadjuvant Therapy in Lung Cancer

Blumenthal, G. M., Bunn, P. A., Chaft, J. E., McCoach, C. E., Perez, E. A., Scagliotti, G. V., Carbone, D. P., Aerts, H. J. W. L., Aisner, D. L., Bergh, J., Berry, D. A., Jarkowski, A., Botwood, N., Cross, D. A. E., Diehn, M., Drezner, N. L., Doebele, R. C., Blakely, C. M., Eberhardt, W. E. E., Felip, E. & 23 others, Gianni, L., Keller, S. P., Leavey, P. J., Malik, S., Pignatti, F., Prowell, T. M., Redman, M. W., Rizvi, N. A., Rosell, R., Rusch, V., de Ruysscher, D., Schwartz, L. H., Sridhara, R., Stahel, R. A., Swisher, S., Taube, J. M., Travis, W. D., Keegan, P., Wiens, J. R., Wistuba, I. I., Wynes, M. W., Hirsch, F. R. & Kris, M. G., Dec 1 2018, In : Journal of Thoracic Oncology. 13, 12, p. 1818-1831 14 p.

Research output: Contribution to journalReview article

13 Scopus citations

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group

Shulman, D. S., Klega, K., Imamovic-Tuco, A., Clapp, A., Nag, A., Thorner, A. R., Van Allen, E., Ha, G., Lessnick, S. L., Gorlick, R., Janeway, K. A., Leavey, P. J., Mascarenhas, L., London, W. B., Vo, K. T., Stegmaier, K., Hall, D., Krailo, M. D., Barkauskas, D. A., DuBois, S. G. & 1 others, Crompton, B. D., Aug 28 2018, In : British Journal of Cancer. 119, 5, p. 615-621 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Hope as a Predictor of Anxiety and Depressive Symptoms Following Pediatric Cancer Diagnosis

Germann, J. N., Leonard, D., Heath, C. L., Stewart, S. M. & Leavey, P. J., Mar 1 2018, In : Journal of Pediatric Psychology. 43, 2, p. 152-161 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Prolonged response to sorafenib in a patient with refractory metastatic osteosarcoma and a somatic PDGFRA D846V mutation

Armstrong, A. E., Walterhouse, D. O., Leavey, P. J., Reichek, J. & Walz, A. L., Jan 1 2018, (Accepted/In press) In : Pediatric Blood and Cancer. e27493.

Research output: Contribution to journalArticle

The American Society of Pediatric Hematology/Oncology workforce assessment: Part 1—Current state of the workforce

on behalf of the American Society of Pediatric Hematology/Oncology Workforce Advisory Taskforce, Feb 1 2018, In : Pediatric Blood and Cancer. 65, 2, e26780.

Research output: Contribution to journalArticle

2 Scopus citations

The American Society of Pediatric Hematology/Oncology workforce assessment: Part 2—Implications for fellowship training

on behalf of the American Society of Pediatric Hematology/Oncology Workforce Advisory Taskforce, Feb 1 2018, In : Pediatric Blood and Cancer. 65, 2, e26765.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Histopathological diagnosis for viable and non-viable tumor prediction for osteosarcoma using convolutional neural network

Mishra, R., Daescu, O., Leavey, P. J., Rakheja, D. & Sengupta, A. L., 2017, Bioinformatics Research and Applications - 13th International Symposium, ISBRA 2017, Proceedings. Springer Verlag, Vol. 10330 LNBI. p. 12-23 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10330 LNBI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Scopus citations
2016

Biomarker development in osteosarcoma—Is there no longer any utility to tumor necrosis?

Leavey, P. J., Oct 1 2016, In : Pediatric Blood and Cancer. 63, 10, p. 1702-1703 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial

Marina, N. M., Smeland, S., Bielack, S. S., Bernstein, M., Jovic, G., Krailo, M. D., Hook, J. M., Arndt, C., van den Berg, H., Brennan, B., Brichard, B., Brown, K. L. B., Butterfass-Bahloul, T., Calaminus, G., Daldrup-Link, H. E., Eriksson, M., Gebhardt, M. C., Gelderblom, H., Gerss, J., Goldsby, R. & 33 others, Goorin, A., Gorlick, R., Grier, H. E., Hale, J. P., Hall, K. S., Hardes, J., Hawkins, D. S., Helmke, K., Hogendoorn, P. C. W., Isakoff, M. S., Janeway, K. A., Jürgens, H., Kager, L., Kühne, T., Lau, C. C., Leavey, P. J., Lessnick, S. L., Mascarenhas, L., Meyers, P. A., Mottl, H., Nathrath, M., Papai, Z., Randall, R. L., Reichardt, P., Renard, M., Safwat, A. A., Schwartz, C. L., Stevens, M. C. G., Strauss, S. J., Teot, L., Werner, M., Sydes, M. R. & Whelan, J. S., Oct 1 2016, In : The Lancet Oncology. 17, 10, p. 1396-1408 13 p.

Research output: Contribution to journalArticle

99 Scopus citations

COMPUTER AIDED IMAGE SEGMENTATION AND CLASSIFICATION FOR VIABLE AND NON-VIABLE TUMOR IDENTIFICATION IN OSTEOSARCOMA

Arunachalam, H. B., Mishra, R., Armaselu, B., Daescu, O., Martinez, M., Leavey, P. J., Rakheja, D., Cederberg, K. B., Sengupta, A. L. & Ni'suilleabhain, M., 2016, In : Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 22, p. 195-206 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015
8 Scopus citations

Humanism and professionalism education for pediatric hematology-oncology fellows: A model for pediatric subspecialty training

Kesselheim, J. C., Atlas, M., Adams, D., Aygun, B., Barfield, R., Eisenman, K., Fulbright, J., Garvey, K., Kersun, L., Nageswara Rao, A., Reilly, A., Sharma, M., Shereck, E., Wang, M., Watt, T. & Leavey, P., Feb 1 2015, In : Pediatric Blood and Cancer. 62, 2, p. 335-340 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

PAX genes in childhood oncogenesis: Developmental biology gone awry?

Mahajan, P., Leavey, P. J. & Galindo, R. L., May 21 2015, In : Oncogene. 34, 21, p. 2681-2689 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney

Roy, A., Kumar, V., Zorman, B., Fang, E., Haines, K. M., Doddapaneni, H., Hampton, O. A., White, S., Bavle, A. A., Patel, N. R., Eldin, K. W., John Hicks, M., Rakheja, D., Leavey, P. J., Skapek, S. X., Amatruda, J. F., Nuchtern, J. G., Chintagumpala, M. M., Wheeler, D. A., Plon, S. E. & 2 others, Sumazin, P. & Parsons, D. W., Nov 17 2015, In : Nature Communications. 6, 8891.

Research output: Contribution to journalArticle

55 Scopus citations

Whole slide images stitching for osteosarcoma detection

Armaselu, B., Arunachalam, H. B., Daescu, O., Bach, J. P., Cederberg, K. B., Rakheja, D., Sengupta, A. L., Skapek, S. X. & Leavey, P. J., Dec 2 2015, 2015 IEEE 5th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2015. Institute of Electrical and Electronics Engineers Inc., 7344718

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2014

Bone scintigraphy in osteosarcoma: A single institution experience

Powers, J. M., Cost, C., Cederberg, K., Leonard, D. & Leavey, P. J., Nov 8 2014, In : Journal of Pediatric Hematology/Oncology. 36, 8, p. e543-e545

Research output: Contribution to journalArticle

3 Scopus citations

Do pediatric hematology/oncology (PHO) fellows receive communication training?

File, W., Bylund, C. L., Kesselheim, J., Leonard, D. & Leavey, P., Mar 1 2014, In : Pediatric Blood and Cancer. 61, 3, p. 502-506 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Hoping is coping: A guiding theoretical framework for promoting coping and adjustment following pediatric cancer diagnosis

Germann, J. N., Leonard, D., Stuenzi, T. J., Pop, R. B., Stewart, S. M. & Leavey, P. J., Oct 27 2014, In : Journal of Pediatric Psychology. 40, 9, p. 846-855 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Important principles in Ewing sarcoma treatment

Leavey, P. J., Dec 1 2014, In : Pediatric Blood and Cancer. 61, 12, p. 2149-2150 2 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

How many physicians do we need? A benchmark for pediatric hematology/oncology

Leavey, P. J., Apr 1 2013, In : Pediatric Blood and Cancer. 60, 4, p. 527-528 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

IL-8 predicts pediatric oncology patients with febrile neutropenia at low risk for bacteremia

Cost, C. R., Stegner, M. M., Leonard, D. & Leavey, P., Apr 1 2013, In : Journal of Pediatric Hematology/Oncology. 35, 3, p. 206-211 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012

Graduate medical education changes: Yes we can or enough already?

Leavey, P. J. & Jubran, R. F., Dec 15 2012, In : Pediatric Blood and Cancer. 59, 7, p. 1168-1172 5 p.

Research output: Contribution to journalReview article

2 Scopus citations

Predictive value of interleukin-5 and monocyte chemotactic protein-1 for bacteremia in children with febrile neutropenia

Aquino, V. M., Cost, C., Gomez, A., Bowers, D. C., Ramilo, O., Ahmad, N., Winick, N. & Leavey, P. J., Aug 1 2012, In : Journal of Pediatric Hematology/Oncology. 34, 6, p. e241-e245

Research output: Contribution to journalArticle

5 Scopus citations
2009

Dose-intensified compared with standard chemotherapy for nonmetastatic ewing sarcoma family of tumors: A children's oncology group study

Granowetter, L., Womer, R., Devidas, M., Krailo, M., Wang, C., Bernstein, M., Marina, N., Leavey, P., Gebhardt, M., Healey, J., Shamberger, R. C., Goorin, A., Miser, J., Meyer, J., Arndt, C. A. S., Sailer, S., Marcus, K., Perlman, E., Dickman, P. & Grier, H. E., May 20 2009, In : Journal of Clinical Oncology. 27, 15, p. 2536-2541 6 p.

Research output: Contribution to journalArticle

187 Scopus citations
2008

Ewing sarcoma: Prognostic criteria, outcomes and future treatment

Leavey, P. J. & Collier, A. B., Apr 1 2008, In : Expert Review of Anticancer Therapy. 8, 4, p. 617-624 8 p.

Research output: Contribution to journalReview article

46 Scopus citations

Prognostic factors for patients with Ewing sarcoma (EWS) at first recurrence following multi-modality therapy: A report from the children's oncology group

Leavey, P. J., Mascarenhas, L., Marina, N., Chen, Z., Krailo, M., Miser, J., Brown, K., Tarbell, N., Bernstein, M. L., Granowetter, L., Gebhardt, M. & Grier, H. E., Sep 1 2008, In : Pediatric Blood and Cancer. 51, 3, p. 334-338 5 p.

Research output: Contribution to journalArticle

94 Scopus citations
2007

Extracorporeal membrane oxygenation (ECMO) initiation without intubation in two children with mediastinal malignancy

Wickiser, J. E., Thompson, M., Leavey, P. J., Quinn, C. T., Garcia, N. M. & Aquino, V. M., Oct 15 2007, In : Pediatric Blood and Cancer. 49, 5, p. 751-754 4 p.

Research output: Contribution to journalArticle

22 Scopus citations
2006

KAI-1 expression in pediatric high-grade osteosarcoma

Leavey, P. J., Timmons, C., Frawley, W., Lombardi, D. & Ashfaq, R., May 1 2006, In : Pediatric and Developmental Pathology. 9, 3, p. 219-224 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

The prevalence and use of antidepressant medication in pediatric cancer patients

Portteus, A., Ahmad, N., Tobey, D. & Leavey, P., Aug 1 2006, In : Journal of Child and Adolescent Psychopharmacology. 16, 4, p. 467-473 7 p.

Research output: Contribution to journalReview article

19 Scopus citations
2004

Phase I Study of Oral Cyclophosphamide and Oral Topotecan for Children with Recurrent or Refractory Solid Tumors

Bowers, D. C., Aquino, V. M., Leavey, P. J., Bash, R. O., Journeycake, J. M., Tomlinson, G., Mulne, A. F., Haynes, H. J. & Winick, N. J., Jan 1 2004, In : Pediatric Blood and Cancer. 42, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

16 Scopus citations
2003

Cyclooxygenase-2 expression does not correlate with outcome in osteosarcoma or rhabdomyosarcoma

Dickens, D. S., Kozielski, R., Leavey, P. J., Timmons, C. & Cripe, T. P., Apr 1 2003, In : Journal of Pediatric Hematology/Oncology. 25, 4, p. 282-285 4 p.

Research output: Contribution to journalArticle

45 Scopus citations

Skip metastasis in osteosarcoma

Leavey, P. J., Day, M. D., Booth, T. & Maale, G., Oct 1 2003, In : Journal of Pediatric Hematology/Oncology. 25, 10, p. 806-808 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

The epidermal growth factor receptor HER2 is not a major therapeutic target in Ewing sarcoma

Ye, D., Maitra, A., Timmons, C. F., Leavey, P. J., Ashfaq, R. & Ilaria, R. L., Jun 1 2003, In : Journal of Pediatric Hematology/Oncology. 25, 6, p. 459-466 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2002

A 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activity

Leavey, P. J., Gonzalez-Aller, C., Thurman, G., Kleinberg, M., Rinckel, L., Ambruso, D. W., Freeman, S., Kuypers, F. A. & Ambruso, D. R., Nov 22 2002, In : Journal of Biological Chemistry. 277, 47, p. 45181-45187 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Effective removal of methotrexate by high-flux hemodialysis

Saland, J. M., Leavey, P. J., Bash, R. O., Hansch, E., Arbus, G. S. & Quigley, R., Dec 1 2002, In : Pediatric Nephrology. 17, 10, p. 825-829 5 p.

Research output: Contribution to journalArticle

51 Scopus citations

In vivo treatment with granulocyte colony-stimulating factor does not delay apoptosis in human neutrophils by increasing the expression of the vacuolar proton ATPase

Zimbelman, J., Thurman, G., Leavey, P. J., Ellison, M. C. & Ambruso, D. R., Jan 1 2002, In : Journal of Investigative Medicine. 50, 1, p. 33-37 5 p.

Research output: Contribution to journalArticle

Variability in dose intensity of high-dose methotrexate for nonmetastatic osteosarcoma

Leavey, P. J., Mantadakis, E. & Maale, G., Oct 1 2002, In : Pediatric Hematology and Oncology. 19, 7, p. 483-489 7 p.

Research output: Contribution to journalArticle

2001

Lack of prognostic significance of intratumoral angiogenesis in nonmetastatic osteosarcoma

Mantadakis, E., Kim, G., Reisch, J., McHard, K., Maale, G., Leavey, P. J. & Timmons, C., Jan 1 2001, In : American Journal of Pediatric Hematology/Oncology. 23, 5, p. 286-289 4 p.

Research output: Contribution to journalArticle

30 Scopus citations
2000

Fractionated cyclophosphamide and etoposide for children with advanced or refractory solid tumors: A phase II window study

Mantadakis, E., Herrera, L., Leavey, P. J., Bash, R. O., Winick, N. J. & Kamen, B. A., Jul 2000, In : Journal of Clinical Oncology. 18, 13, p. 2576-2581 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Functional characteristics of neutrophils collected and stored after administration of G-CSF

Leavey, P. J., Thurman, G. & Ambruso, D. R., May 10 2000, In : Transfusion. 40, 4, p. 414-419 6 p.

Research output: Contribution to journalArticle

31 Scopus citations
1998

In vivo treatment with granulocyte colony-stimulating factor results in divergent effects on neutrophil functions measured in vitro

Leavey, P. J., Sellins, K. S., Thurman, G., Elzi, D., Hiester, A., Silliman, C. C., Zerbe, G., Cohen, J. J. & Ambruso, D. R., Dec 1 1998, In : Blood. 92, 11, p. 4366-4374 9 p.

Research output: Contribution to journalArticle

67 Scopus citations

The Effects of Stem Cell Factor and Granulocyte Colony Stimulating Factor Therapy on the Activity of the Neutrophil NADPH Oxidase Enzyme System

Leavey, P. J., Thurman, G., Gonzalez-Aller, C., Zerbe, G. & Ambruso, D. R., Apr 1998, In : Journal of Investigative Medicine. 46, 4, p. 121-126 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
1997

Intra-operative radiation therapy in pediatric neuroblastoma

Leavey, P. J., Odom, L. F., Poole, M., McNeely, L., Tyson, R. W. & Haase, G. M., May 28 1997, In : Medical and Pediatric Oncology. 28, 6, p. 424-428 5 p.

Research output: Contribution to journalArticle

23 Scopus citations
1996

Granulocyte colony stimulating factor (filgrastim) administration to normal volunteers prolongs the survival of isolated neutrophils

Leavey, P. J., Sellins, K. S., Cohen, J. J. & Ambruso, D. R., Jan 1 1996, In : Journal of Investigative Medicine. 44, 3, p. 231a

Research output: Contribution to journalArticle

1 Scopus citations
1992

Osteogenic sarcoma and Rothmund Thomson syndrome

Varughese, M., Leavey, P., Smith, P., Sneath, R., Breatnach, F. & O'Meara, A., May 1 1992, In : Journal of Cancer Research and Clinical Oncology. 118, 5, p. 389-390 2 p.

Research output: Contribution to journalArticle

23 Scopus citations