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Research Output

  • 2683 Citations
  • 12 h-Index
  • 12 Article
  • 1 Comment/debate
2011

Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression

Zhang, L., Li, P., Hsu, T., Aguilar, H. R., Frantz, D. E., Schneider, J. W., Bachoo, R. & Hsieh, J., Apr 1 2011, In : Differentiation. 81, 4, p. 233-242 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Structure of C3PO and mechanism of human RISC activation

Ye, X., Huang, N., Liu, Y., Paroo, Z., Huerta, C., Li, P., Chen, S., Liu, Q. & Zhang, H., Jun 2011, In : Nature Structural and Molecular Biology. 18, 6, p. 650-657 8 p.

Research output: Contribution to journalArticle

98 Scopus citations
2009

The novel epididymis-specific beta-galactosidase-like gene Glb1I4 is essential in epididymal development and sperm maturation in rats

Zhen, W., Li, P., He, B., Guo, J. & Zhang, Y. L., Apr 1 2009, In : Biology of reproduction. 80, 4, p. 696-706 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
2008

Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis

Lee, Y. K., Schmidt, D. R., Cummins, C. L., Choi, M., Li, P., Zhang, Y., Goodwin, B., Hammer, R. E., Mangelsdorf, D. J. & Kliewer, S. A., Jun 2008, In : Molecular Endocrinology. 22, 6, p. 1345-1356 12 p.

Research output: Contribution to journalArticle

98 Scopus citations

Structural basis of human pregnane X receptor activation by the hops constituent colupulone

Teotico, D. G., Bischof, J. J., Peng, L., Kliewer, S. A. & Redinbo, M. R., Dec 1 2008, In : Molecular Pharmacology. 74, 6, p. 1512-1520 9 p.

Research output: Contribution to journalArticle

49 Scopus citations
2007

Crystal structure of the pregnane X receptor-estradiol complex provides insights into endobiotic recognition

Xue, Y., Moore, L. B., Orans, J., Peng, L., Bencharit, S., Kliewer, S. A. & Redinbo, M. R., May 1 2007, In : Molecular Endocrinology. 21, 5, p. 1028-1038 11 p.

Research output: Contribution to journalArticle

74 Scopus citations

Erratum: Crystal structure of the pregnane X receptor-estradiol complex provides insights into endobiotic recognition (Molecular Endocrinology (2007) 21, 5, (1028-1038))

Xue, Y., Moore, L. B., Orans, J., Peng, L., Bencharit, S., Kliewer, S. A. & Redinbo, M. R., Jun 2007, In : Molecular Endocrinology. 21, 6, p. 1488-1489 2 p.

Research output: Contribution to journalComment/debate

2006

Identification of a hormonal basis for gallbladder filling

Choi, M., Moschetta, A., Bookout, A. L., Peng, L., Umetani, M., Holmstrom, S. R., Suino-Powell, K., Xu, H. E., Richardson, J. A., Gerard, R. D., Mangelsdorf, D. J. & Kliewer, S. A., Nov 1 2006, In : Nature medicine. 12, 11, p. 1253-1255 3 p.

Research output: Contribution to journalArticle

192 Scopus citations

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

Inagaki, T., Moschetta, A., Lee, Y. K., Peng, L., Zhao, G., Downes, M., Yu, R. T., Shelton, J. M., Richardson, J. A., Repa, J. J., Mangelsdorf, D. J. & Kliewer, S. A., Mar 7 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 10, p. 3920-3925 6 p.

Research output: Contribution to journalArticle

560 Scopus citations
2005

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., Gerard, R. D., Repa, J. J., Mangelsdorf, D. J. & Kliewer, S. A., Oct 1 2005, In : Cell Metabolism. 2, 4, p. 217-225 9 p.

Research output: Contribution to journalArticle

1043 Scopus citations

Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development

Gu, P., Goodwin, B., Chung, A. C. K., Xu, X., Wheeler, D. A., Price, R. R., Galardi, C., Peng, L., Latour, A. M., Koller, B. H., Gossen, J., Kliewer, S. A. & Cooney, A. J., May 2005, In : Molecular and cellular biology. 25, 9, p. 3492-3505 14 p.

Research output: Contribution to journalArticle

212 Scopus citations

Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin

Chrencik, J. E., Orans, J., Moore, L. B., Xue, Y., Peng, L., Collins, J. L., Wisely, G. B., Lambert, M. H., Kliewer, S. A. & Redinbo, M. R., May 1 2005, In : Molecular Endocrinology. 19, 5, p. 1125-1134 10 p.

Research output: Contribution to journalArticle

156 Scopus citations
2004

The nuclear xenobiotic receptor CAR: Structural determinants of constitutive activation and heterodimerization

Suino, K., Peng, L., Reynolds, R., Li, Y., Cha, J. Y., Repa, J. J., Kliewer, S. A. & Xu, H. E., Dec 22 2004, In : Molecular cell. 16, 6, p. 893-905 13 p.

Research output: Contribution to journalArticle

163 Scopus citations