• 20084 Citations
  • 77 h-Index
1976 …2020

Research output per year

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Research Output

1990

Expression of 11β-hydroxysteroid dehydrogenase using recombinant vaccinia virus

Agarwal, A. K., Tusie-Luna, M. T., Monder, C. & White, P. C., Dec 1990, In : Molecular Endocrinology. 4, 12, p. 1827-1832 6 p.

Research output: Contribution to journalArticle

Open Access
162 Scopus citations

First trimester prenatal treatment and molecular genetic diagnosis of congenital adrenal hyperplasia (21-hydroxylase deficiency)

Speiser, P. W., Laforgia, N., Kato, K., Pareira, J., Khan, R., Yang, S. Y., Whorwood, C., White, P. C., Elias, S., Schriock, E., Schriock, E., Simpson, J. L., Taslimi, M., Najjar, J., May, S., Mills, G., Crawford, C. & New, M. I., Oct 1990, In : Obstetrical and Gynecological Survey. 45, 10, p. 707-709 3 p.

Research output: Contribution to journalArticle

First trimester prenatal treatment and molecular genetic diagnosis of congenital adrenal hyperplasia (21-hydroxylase deficiency)

Speiser, P. W., Laforgia, N., Kato, K., Pareira, J., Khan, R., Yang, S. Y., Whorwood, C., White, P. C., Elias, S., Schriock, E., Schriock, E., Simpson, J. L., Taslimi, M., Najjar, J., May, S., Mills, G., Crawford, C. & New, M. I., Apr 1990, In : Journal of Clinical Endocrinology and Metabolism. 70, 4, p. 838-848 11 p.

Research output: Contribution to journalArticle

104 Scopus citations
1991

Aldosterone Synthesis in Salt-Wasting Congenital Adrenal Hyperplasia with Complete Absence of Adrenal 21-Hydroxylase

Speiser, P. W., Agdere, L., Ueshiba, H., White, P. C. & New, M. I., Jan 17 1991, In : New England Journal of Medicine. 324, 3, p. 145-149 5 p.

Research output: Contribution to journalArticle

67 Scopus citations

A mutation (pro-30 to leu) in CYP21 represents a potential nonclassic steroid 21-hydroxylase deficiency allele

Tusie-Luna, M. T., Speiser, P. W., Dumic, M., New, M. I. & White, P. C., May 1 1991, In : Molecular Endocrinology. 5, 5, p. 685-692 8 p.

Research output: Contribution to journalArticle

Open Access
155 Scopus citations

A mutation in CYP11B1 (Arg-448 → His) associated with steroid 11β-hydroxylase deficiency in Jews of Moroccan origin

White, P. C., Dupont, J., New, M. I., Leiberman, E., Hochberg, Z. & Rösler, A., 1991, In : Journal of Clinical Investigation. 87, 5, p. 1664-1667 4 p.

Research output: Contribution to journalArticle

Open Access
190 Scopus citations

Defects in cortisol metabolism causing low-renin hypertension

White, P. C., Jan 1 1991, In : Endocrine Research. 17, 1-2, p. 85-107 23 p.

Research output: Contribution to journalArticle

8 Scopus citations

Distribution of deletions and seven point mutations on CYP21B genes in three clinical forms of steroid 21-hydroxylase deficiency

Mornet, E., Crété, P., Kuttenn, F., Raux-Demay, M. C., Boué, J., White, P. C. & Boué, A., Feb 4 1991, In : American Journal of Human Genetics. 48, 1, p. 79-88 10 p.

Research output: Contribution to journalArticle

127 Scopus citations

Molecular cloning and expression of rat liver 3α-hydroxysteroid dehydrogenase

Cheng, K. C., White, P. C. & Qin, K. N., Jun 1 1991, In : Molecular Endocrinology. 5, 6, p. 823-828 6 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations

Molecular pathology of steroid 21-hydroxylase deficiency

Strachan, T. & White, P. C., 1991, In : Journal of Steroid Biochemistry and Molecular Biology. 40, 4-6, p. 537-543 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
414 Scopus citations

The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex

Curnow, K. M., Tusie-Luna, M. T., Pascoe, L., Natarajan, R., Gu, J. L., Nadler, J. L. & White, P. C., Oct 1991, In : Molecular Endocrinology. 5, 10, p. 1513-1522 10 p.

Research output: Contribution to journalArticle

Open Access
285 Scopus citations
1992

A novel gene constitutively expressed in human lymphoid cells is inducible with interferon-γ in myeloid cells

Trapani, J. A., Browne, K. A., Dawson, M. J., Ramsay, R. G., Eddy, R. L., Shows, T. B., White, P. C. & Dupont, B., Sep 1992, In : Immunogenetics. 36, 6, p. 369-376 8 p.

Research output: Contribution to journalArticle

85 Scopus citations

Disease expression and molecular genotype in congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Speiser, P. W., Dupont, J., Zhu, D., Serrat, J., Buegeleisen, M., Tusie-Luna, M. T., Lesser, M., New, M. I. & White, P. C., 1992, In : Journal of Clinical Investigation. 90, 2, p. 584-595 12 p.

Research output: Contribution to journalArticle

Open Access
467 Scopus citations

Disorders of steroid 11β-hydroxylase isozymes

White, P. C. & Pascoe, L., Aug 1992, In : Trends in Endocrinology and Metabolism. 3, 6, p. 229-234 6 p.

Research output: Contribution to journalReview article

8 Scopus citations

Genetic analysis of the human type-1 angiotensin II receptor

Curnow, K. M., Pascoe, L. & White, P. C., Jul 1 1992, In : Molecular Endocrinology. 6, 7, p. 1113-1118 6 p.

Research output: Contribution to journalArticle

101 Scopus citations
90 Scopus citations

Genomic organization and chromosomal location of the human gene encoding the B-lymphocyte activation antigen B7

Selvakumar, A., Mohanraj, B. K., Eddy, R. L., Shows, T. B., White, P. C. & Dupont, B., May 1992, In : Immunogenetics. 36, 3, p. 175-181 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Genotype of Yupik Eskimos with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Speisere, P. W., New, M. I., Tannin, G. M., Pickering, D., Yang, S. Y. & White, P. C., Mar 1992, In : Human genetics. 88, 6, p. 647-648 2 p.

Research output: Contribution to journalArticle

32 Scopus citations

Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2

Pascoe, L., Curnow, K. M., Slutsker, L., Connell, J. M. C., Speiser, P. W., New, M. I. & White, P. C., 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 17, p. 8327-8331 5 p.

Research output: Contribution to journalArticle

Open Access
215 Scopus citations

Molecular biology of 11β-hydroxylase and 11β-hydroxysteroid dehydrogenase enzymes

White, P. C., Pascoe, L., Curnow, K. M., Tannin, G. & Rösler, A., Dec 1992, In : Journal of Steroid Biochemistry and Molecular Biology. 43, 8, p. 827-835 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Mutations in the human CYP11B2 (aldosterone synthase) gene causing corticosterone methyloxidase II deficiency

Pascoe, L., Curnow, K. M., Slutsker, L., Rösler, A. & White, P. C., 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 11, p. 4996-5000 5 p.

Research output: Contribution to journalArticle

Open Access
158 Scopus citations

Polymorphism in the RD (D6S45) gene

White, P. C., Vitek, J., Lahita, R. G. & Speiser, P. W., May 1 1992, In : Human genetics. 89, 2, p. 243-244 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Prenatal diagnosis/treatment in families at risk for infants with steroid 21-hydroxylase deficiency (congenital adrenal hyperplasia)

Karaviti, L. P., Mercado, A. B., Mercado, M. B., Speiser, P. W., Buegeleisen, M., Crawford, C., Antonian, L., White, P. C. & New, M. I., Mar 1992, In : Journal of Steroid Biochemistry and Molecular Biology. 41, 3-8, p. 445-451 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

R339H and P453s: CYP21 mutations associated with nonclassic steroid 21-hydroxylase deficiency that are not apparent gene conversions

Helmberg, A., Tusie-Luna, M. T., Tabarelli, M., Kofler, R. & White, P. C., Aug 1992, In : Molecular Endocrinology. 6, 8, p. 1318-1322 5 p.

Research output: Contribution to journalArticle

Open Access
105 Scopus citations

Tyr-179 and Lys-183 are essential for enzymatic activity of 11β-hydroxysteroid dehydrogenase

Obeid, J. & White, P. C., Oct 15 1992, In : Biochemical and Biophysical Research Communications. 188, 1, p. 222-227 6 p.

Research output: Contribution to journalArticle

104 Scopus citations
1993

11β-Hydroxysteroid Dehydrogenase

Monder, C. & White, P. C., Jan 1 1993, In : Vitamins and Hormones. 47, C, p. 187-271 85 p.

Research output: Contribution to journalArticle

208 Scopus citations

Defects in the HSD11 gene encoding 11 β-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency

Nikkilä, H., Tannin, G. M., New, M. I., Taylor, N. F., Kalaitzoglou, G., Monder, C. & White, P. C., Sep 1993, In : Journal of Clinical Endocrinology and Metabolism. 77, 3, p. 687-691 5 p.

Research output: Contribution to journalArticle

100 Scopus citations

Genomic organization of the mouse B-lymphocyte activation antigen B7

Selvakumar, A., White, P. C. & Dupont, B., Jun 1993, In : Immunogenetics. 38, 4, p. 292-295 4 p.

Research output: Contribution to journalArticle

23 Scopus citations
19 Scopus citations

Mutations in the CYP11B1 gene causing congenital adrenal hyperplasia and hypertension cluster in exons 6, 7, and 8

Curnow, K. M., Slutsker, L., Vitek, J., Cole, T., Speiser, P. W., New, M. I., White, P. C. & Pascoe, L., 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 10, p. 4552-4556 5 p.

Research output: Contribution to journalArticle

Open Access
171 Scopus citations

Transcripts originating in intron 1 of the HSD11 (11 β-hydroxysteroid dehydrogenase) gene encode a truncated polypeptide that is enzymatically inactive

Obeid, J., Curnow, K. M., Aisenberg, J. & White, P. C., Dec 1993, In : Molecular Endocrinology. 7, 2, p. 154-160 7 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations
1994

Defects in the HSD11 gene encoding 11β-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency

Nikkilä, H., Tannin, G. M., New, M. I., Taylor, N. F., Kalaitzoglou, G., Monder, C. & White, P. C., Jun 1 1994, In : Pediatric Nephrology. 8, 3, 1 p.

Research output: Contribution to journalArticle

Disorders of aldosterone biosynthesis and action

White, P. C., Jul 28 1994, In : New England Journal of Medicine. 331, 4, p. 250-258 9 p.

Research output: Contribution to journalReview article

162 Scopus citations

Disorders of Steroid 1lβ-Hydroxylase Isozymes*

White, P. C., Curnow, K. M. & Pascoe, L., Aug 1994, In : Endocrine reviews. 15, 4, p. 421-438 18 p.

Research output: Contribution to journalArticle

275 Scopus citations

Genetic analysis of 11β-hydroxysteroid dehydrogenase

White, P. C., Obeid, J., Agarwal, A. K., Tannin, G. M. & Nikkila, H., Feb 1994, In : Steroids. 59, 2, p. 111-115 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Genetic diseases of steroid metabolism.

White, P. C., 1994, In : Vitamins and Hormones. 49, p. 131-195 65 p.

Research output: Contribution to journalArticle

42 Scopus citations

Molecular genetic prenatal diagnosis of congenital adrenalhyperplasia due to 21-hydroxylase deficiency by allele-specific hybridization

Speiser, P. W., White, P. C., Dupont, J., Zhu, D., Mercado, A. & New, M. I., Jan 1 1994, In : Recent progress in hormone research. 49, 1, p. 367-371 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mutations in Steroid 21‐Hydroxylase (CYP21)

White, P. C., Tusie-Luna, M. T., New, M. I. & Speiser, P. W., 1994, In : Human mutation. 3, 4, p. 373-378 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

NAD+-dependent isoform of 11β-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney

Agarwal, A. K., Mune, T., Monder, C. & White, P. C., 1994, In : Journal of Biological Chemistry. 269, 42, p. 25959-25962 4 p.

Research output: Contribution to journalArticle

252 Scopus citations

Prenatal diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency by allele-specific hybridization and Southern blot

Speiser, P. W., White, P. C., Dupont, J., Zhu, D., Mercado, A. B. & New, M. I., Apr 1994, In : Human genetics. 93, 4, p. 424-428 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Steroid 11β-hydroxylase deficiency and related disorders

White, P. C. & Speiser, P. W., Jan 1 1994, In : Endocrinology and Metabolism Clinics of North America. 23, 2, p. 325-339 15 p.

Research output: Contribution to journalReview article

39 Scopus citations
1995

Alternatively spliced human type 1 angiotensin II receptor mRNAs are translated at different efficiencies and encode two receptor isoforms

Curnow, K. M., Pascoe, L., Davies, E., White, P. C., Corvol, P. & Clauser, E., Sep 1 1995, In : Molecular Endocrinology. 9, 9, p. 1250-1262 13 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Analysis of the human gene encoding the kidney isozyme of 11β-hydroxysteroid dehydrogenase

Agarwal, A. K., Rogerson, F. M., Mune, T. & White, P. C., Dec 1995, In : Journal of Steroid Biochemistry and Molecular Biology. 55, 5-6, p. 473-479 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Clinical, biochemical and genetic features of five extended kindred's with glucocorticoid-suppressible hyperaldosteronism

Jamieson, A., Slutsker, L., Inglis, G., Campbell, M., Fraser, R., White, P. & Connell, J., Jan 1 1995, In : Endocrine Research. 21, 1-2, p. 463-469 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cloning of cDNA encoding an NAD+-dependent isoform of 11βhydroxysteroid dehydrogenase in sheep kidney

Agarwal, A. K., Mune, T., Monder, C. & White, P. C., Jan 1 1995, In : Endocrine Research. 21, 1-2, p. 389-397 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Detection of steroid 21-hydroxylase alleles using gene-specific PCR and a multiplexed ligation detection reaction

Day, D. J., Speiser, P. W., White, P. C. & Barany, F., Sep 1 1995, In : Genomics. 29, 1, p. 152-162 11 p.

Research output: Contribution to journalArticle

105 Scopus citations

Four is not more than two

Russell, D. W. & White, P. C., Jan 1 1995, In : American Journal of Human Genetics. 57, 5, p. 1002-1005 4 p.

Research output: Contribution to journalEditorial

6 Scopus citations

Functional studies of 11β-hydroxysteroid dehydrogenase

White, P. C., Mune, T. & Agarwal, A. K., Jan 1995, In : Steroids. 60, 1, p. 65-68 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
Open Access
144 Scopus citations