• 19997 Citations
  • 77 h-Index
1976 …2019

Research output per year

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Research Output

1992

Polymorphism in the RD (D6S45) gene

White, P. C., Vitek, J., Lahita, R. G. & Speiser, P. W., May 1 1992, In : Human genetics. 89, 2, p. 243-244 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Prenatal diagnosis/treatment in families at risk for infants with steroid 21-hydroxylase deficiency (congenital adrenal hyperplasia)

Karaviti, L. P., Mercado, A. B., Mercado, M. B., Speiser, P. W., Buegeleisen, M., Crawford, C., Antonian, L., White, P. C. & New, M. I., Mar 1992, In : Journal of Steroid Biochemistry and Molecular Biology. 41, 3-8, p. 445-451 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

R339H and P453s: CYP21 mutations associated with nonclassic steroid 21-hydroxylase deficiency that are not apparent gene conversions

Helmberg, A., Tusie-Luna, M. T., Tabarelli, M., Kofler, R. & White, P. C., Aug 1992, In : Molecular Endocrinology. 6, 8, p. 1318-1322 5 p.

Research output: Contribution to journalArticle

Open Access
105 Scopus citations

Tyr-179 and Lys-183 are essential for enzymatic activity of 11β-hydroxysteroid dehydrogenase

Obeid, J. & White, P. C., Oct 15 1992, In : Biochemical and Biophysical Research Communications. 188, 1, p. 222-227 6 p.

Research output: Contribution to journalArticle

104 Scopus citations
1991

Aldosterone Synthesis in Salt-Wasting Congenital Adrenal Hyperplasia with Complete Absence of Adrenal 21-Hydroxylase

Speiser, P. W., Agdere, L., Ueshiba, H., White, P. C. & New, M. I., Jan 17 1991, In : New England Journal of Medicine. 324, 3, p. 145-149 5 p.

Research output: Contribution to journalArticle

67 Scopus citations

A mutation (pro-30 to leu) in CYP21 represents a potential nonclassic steroid 21-hydroxylase deficiency allele

Tusie-Luna, M. T., Speiser, P. W., Dumic, M., New, M. I. & White, P. C., May 1 1991, In : Molecular Endocrinology. 5, 5, p. 685-692 8 p.

Research output: Contribution to journalArticle

Open Access
155 Scopus citations

A mutation in CYP11B1 (Arg-448 → His) associated with steroid 11β-hydroxylase deficiency in Jews of Moroccan origin

White, P. C., Dupont, J., New, M. I., Leiberman, E., Hochberg, Z. & Rösler, A., Jan 1 1991, In : Journal of Clinical Investigation. 87, 5, p. 1664-1667 4 p.

Research output: Contribution to journalArticle

Open Access
190 Scopus citations

Defects in cortisol metabolism causing low-renin hypertension

White, P. C., Jan 1 1991, In : Endocrine Research. 17, 1-2, p. 85-107 23 p.

Research output: Contribution to journalArticle

8 Scopus citations

Distribution of deletions and seven point mutations on CYP21B genes in three clinical forms of steroid 21-hydroxylase deficiency

Mornet, E., Crété, P., Kuttenn, F., Raux-Demay, M. C., Boué, J., White, P. C. & Boué, A., Feb 4 1991, In : American Journal of Human Genetics. 48, 1, p. 79-88 10 p.

Research output: Contribution to journalArticle

126 Scopus citations

Molecular cloning and expression of rat liver 3α-hydroxysteroid dehydrogenase

Cheng, K. C., White, P. C. & Qin, K. N., Jun 1 1991, In : Molecular Endocrinology. 5, 6, p. 823-828 6 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations

Molecular pathology of steroid 21-hydroxylase deficiency

Strachan, T. & White, P. C., 1991, In : Journal of Steroid Biochemistry and Molecular Biology. 40, 4-6, p. 537-543 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

The human gene for 11β-hydroxysteroid dehydrogenase: Structure, tissue distribution, and chromosomal localization

Tannin, G. M., Agarwal, A. K., Monder, C., New, M. I. & White, P. C., Nov 1 1991, In : Journal of Biological Chemistry. 266, 25, p. 16653-16658 6 p.

Research output: Contribution to journalArticle

413 Scopus citations

The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex

Curnow, K. M., Tusie-Luna, M. T., Pascoe, L., Natarajan, R., Gu, J. L., Nadler, J. L. & White, P. C., Oct 1991, In : Molecular Endocrinology. 5, 10, p. 1513-1522 10 p.

Research output: Contribution to journalArticle

Open Access
283 Scopus citations
1990

11Beta‐Hydroxysteroid Dehydrogenase Messenger Ribonucleic Acid Expression, Bioactivity and Immunoreactivity in Rat Cerebellum

Moisan, M. P., Seckl, J. R., Brett, L. P., Monder, C., Agarwal, A. K., White, P. C. & Edwards, C. R. W., Dec 1990, In : Journal of Neuroendocrinology. 2, 6, p. 853-858 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Characterization of 11 β-hydroxysteroid dehydrogenase gene expression: Identification of multiple unique forms of messenger ribonucleic acid in the rat kidney

Krozowski, Z., Stuchbery, S., White, P., Monder, C. & Funder, J. W., Dec 1990, In : Endocrinology. 127, 6, p. 3009-3013 5 p.

Research output: Contribution to journalArticle

93 Scopus citations

Determination of functional effects of mutations in the steroid 21-hydroxylase gene (CYP21) using recombinant vaccinia virus

Tusie-Luna, M. T., Traktman, P. & White, P. C., Dec 1 1990, In : Journal of Biological Chemistry. 265, 34, p. 20916-20922 7 p.

Research output: Contribution to journalArticle

190 Scopus citations

Expression of 11β-hydroxysteroid dehydrogenase using recombinant vaccinia virus

Agarwal, A. K., Tusie-Luna, M. T., Monder, C. & White, P. C., Dec 1990, In : Molecular Endocrinology. 4, 12, p. 1827-1832 6 p.

Research output: Contribution to journalArticle

Open Access
162 Scopus citations

First trimester prenatal treatment and molecular genetic diagnosis of congenital adrenal hyperplasia (21-hydroxylase deficiency)

Speiser, P. W., Laforgia, N., Kato, K., Pareira, J., Khan, R., Yang, S. Y., Whorwood, C., White, P. C., Elias, S., Schriock, E., Schriock, E., Simpson, J. L., Taslimi, M., Najjar, J., May, S., Mills, G., Crawford, C. & New, M. I., Oct 1990, In : Obstetrical and Gynecological Survey. 45, 10, p. 707-709 3 p.

Research output: Contribution to journalArticle

First trimester prenatal treatment and molecular genetic diagnosis of congenital adrenal hyperplasia (21-hydroxylase deficiency)

Speiser, P. W., Laforgia, N., Kato, K., Pareira, J., Khan, R., Yang, S. Y., Whorwood, C., White, P. C., Elias, S., Schriock, E., Schriock, E., Simpson, J. L., Taslimi, M., Najjar, J., May, S., Mills, G., Crawford, C. & New, M. I., Apr 1990, In : Journal of Clinical Endocrinology and Metabolism. 70, 4, p. 838-848 11 p.

Research output: Contribution to journalArticle

104 Scopus citations
1989

Analysis of mutations causing steroid 21-hydroxylase deficiency

White, P. C., Jan 1 1989, In : Endocrine Research. 15, 1-2, p. 239-256 18 p.

Research output: Contribution to journalArticle

22 Scopus citations

Characterization of two genes encoding human steroid 11β-hydroxylase (P-450(11β))

Mornet, E., Dupont, J., Vitek, A. & White, P. C., Dec 1 1989, In : Journal of Biological Chemistry. 264, 35, p. 20961-20967 7 p.

Research output: Contribution to journalArticle

418 Scopus citations

Clinical and genetic characterization of nonclassic 21-hydroxylase deficiency

Speiser, P. W., New, M. I. & White, P. C., Jan 1 1989, In : Endocrine Research. 15, 1-2, p. 257-276 20 p.

Research output: Contribution to journalArticle

4 Scopus citations

Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase

Agarwal, A. K., Monder, C., Eckstein, B. & White, P. C., Dec 1 1989, In : Journal of Biological Chemistry. 264, 32, p. 18939-18943 5 p.

Research output: Contribution to journalArticle

430 Scopus citations

Steroid 21-hydroxylase deficiency

White, P. C., Crawford, C. & New, M. I., Jan 1 1989, In : Current opinion in pediatrics. 1, 2, p. 436-440 5 p.

Research output: Contribution to journalReview article

2 Scopus citations

Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11β-hydroxylase

Mouw, A. R., Rice, D. A., Meade, J. C., Chua, S. C., White, P. C., Schimmer, B. P. & Parker, K. L., Jan 1 1989, In : Journal of Biological Chemistry. 264, 2, p. 1305-1309 5 p.

Research output: Contribution to journalArticle

56 Scopus citations

Structure of the Human RD Gene: A Highly Conserved Gene in the Class III Region of the Major Histocompatibility Complex

Speiser, P. W. & White, P. C., Dec 1989, In : DNA. 8, 10, p. 745-751 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
1988

6 Molecular genetics of congenital adrenal hyperplasia

White, P. C. & New, M. I., Nov 1988, In : Bailliere's Clinical Endocrinology and Metabolism. 2, 4, p. 941-965 25 p.

Research output: Contribution to journalArticle

17 Scopus citations

An Inherited Defect in Aldosterone Biosynthesis Caused by a Mutation in or near the Gene for Steroid 11-Hydroxylase

Globerman, H., Rosler, A., Theodor, R., New, M. I. & White, P. C., Nov 3 1988, In : New England Journal of Medicine. 319, 18, p. 1193-1197 5 p.

Research output: Contribution to journalArticle

45 Scopus citations

Characterization of frequent deletions causing steroid 21-hydroxylase deficiency

White, P. C., Vitek, A., Dupont, B. & New, M. I., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 12, p. 4436-4440 5 p.

Research output: Contribution to journalArticle

Open Access
199 Scopus citations

Immunohistochemical localization of cytochrome P-450C21 in human adrenal cortex and its relation to endocrine function

Sasano, H., White, P. C., New, M. I. & Sasano, N., Feb 1988, In : Human Pathology. 19, 2, p. 181-185 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Immunohistochemistry of cytochrome P-450 21-hydroxylase: Microscopic examination of the enzyme in the bovine adrenal cortex and kidney

Sasano, H., White, P. C., New, M. I. & Sasano, N., Jan 1988, In : Endocrinology. 122, 1, p. 291-295 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes

Trapani, J. A., Klein, J. L., White, P. C. & Dupont, B., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 18, p. 6924-6928 5 p.

Research output: Contribution to journalArticle

Open Access
83 Scopus citations

Molecular Genetic Analysis of Nonclassic Steroid 21-Hydroxylase Deficiency Associated with HLA-B14,DR1

Speiser, P. W., New, M. I. & White, P. C., Jul 7 1988, In : New England Journal of Medicine. 319, 1, p. 19-23 5 p.

Research output: Contribution to journalArticle

166 Scopus citations

Molecular genetic analysis of nonclassic steroid 21 hydroxylase deficiency associated with hla b14 dri

Speiser, P. W., New, M. I. & White, P. C., 1988, In : Obstetrical and Gynecological Survey. 43, 11, p. 693-694 2 p.

Research output: Contribution to journalArticle

Mutation in the CYP21B gene (Ile-172→Asn) causes steroid 21-hydroxylase deficiency

Amor, M., Parker, K. L., Globerman, H., New, M. I. & White, P. C., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 5, p. 1600-1604 5 p.

Research output: Contribution to journalArticle

Open Access
199 Scopus citations

Nonsense mutation causing steroid 21-hydroxylase deficiency

Globerman, H., Amor, M., Parker, K. L., New, M. I. & White, P. C., Jan 1 1988, In : Journal of Clinical Investigation. 82, 1, p. 139-144 6 p.

Research output: Contribution to journalArticle

Open Access
100 Scopus citations

Prenatal diagnosis of 21-hydroxylase deficiency by the complementary deoxyribonucleic acid probe for cytochrome P-450C-21OH

Reindollar, R. H., Lewis, J. B., White, P. C., Fernhoff, P. M., McDonough, P. G. & Whitney, J. B., Mar 1988, In : American journal of obstetrics and gynecology. 158, 3 PART 1, p. 545-547 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

λPMV: A Bacteriophage Vector Allowing Single-Step Retrieval of cDNAs Following Expression in Mammalian Cells

DiSanto, J. P., Small, T. N., Flomenberg, N. & White, P. C., Dec 1988, In : DNA. 7, 10, p. 735-741 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
1987

Analysis of Steroid 21-Hydroxylase Gene in Five Unrelated Japanese Patients with 21-Hydroxylase Deficiency

Nakura, J., Miki, T., Fukuchi, K. I., Shimizu, K., Nose, O., Takai, S., White, P. C., Honjo, T. & Kumahara, Y., Jan 1 1987, In : Endocrinologia Japonica. 34, 3, p. 373-379 7 p.

Research output: Contribution to journalArticle

Open Access

Cloning of cDNA encoding steroid 11 beta-hydroxylase (P450c11).

Chua, S. C., Szabo, P., Vitek, A., Grzeschik, K. H., John, M. & White, P. C., Oct 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 20, p. 7193-7197 5 p.

Research output: Contribution to journalArticle

Open Access
179 Scopus citations

Congenital Adrenal Hyperplasia

White, P. C., New, M. I. & Dupont, B., Jun 18 1987, In : New England Journal of Medicine. 316, 25, p. 1580-1586 7 p.

Research output: Contribution to journalReview article

194 Scopus citations

Congenital Adrenal Hyperplasia

White, P. C., New, M. I. & Dupont, B., Jun 11 1987, In : New England Journal of Medicine. 316, 24, p. 1519-1524 6 p.

Research output: Contribution to journalReview article

161 Scopus citations

Congenital Adrenal Hyperplasia

Miller, W. L., White, P. C., New, M. & Dupont, B., Nov 26 1987, In : New England Journal of Medicine. 317, 22, p. 1413-1415 3 p.

Research output: Contribution to journalLetter

7 Scopus citations

Frequent deletion and duplication of the steroid 21-hydroxylase genes

Werkmeister, J. W., New, M. I., Dupont, B. O. & White, P. C., 1987, In : Obstetrical and Gynecological Survey. 42, 9, p. 572-573 2 p.

Research output: Contribution to journalArticle

Genetics of steroid 21-hydroxylase deficiency.

White, P. C., 1987, In : Recent progress in hormone research. 43, p. 305-336 32 p.

Research output: Contribution to journalReview article

18 Scopus citations

UNTERSUCHUNGEN ZUR MOLEKULAREN BIOLOGIE DES ADRENOGENITALEN SYNDROMS. NEUE MOGLICHKEITEN DES HETERO-ZYGOTEN-SCREENING

Translated title of the contribution: Molecular biology of the adrenogenital syndrome. New possibilities of heterozygote screeningBohm, B. O., Rosak, C., Bohm, T. L. J., White, P. C. & Schöffling, K., Feb 27 1987, In : Deutsche Medizinische Wochenschrift. 112, 3, p. 87-89 3 p.

Research output: Contribution to journalArticle

1986

Associations between restriction fragment length polymorphisms detected with a probe for human 21-hydroxylase (21-OH) and two clinical forms of 21-OH deficiency

Mornet, E., Couillin, P., Kutten, F., Raux, M. C., White, P. C., Cohen, D., Boué, A. & Dausset, J., Dec 1 1986, In : Human genetics. 74, 4, p. 402-408 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Bovine Steroid 21-Hydroxylase: Regulation of Biosynthesis

John, M. E., Okamura, T., Dee, A., Adler, B., John, M. C., White, P. C., Simpson, E. R. & Waterman, M. R., May 1986, In : Biochemistry. 25, 10, p. 2846-2853 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Classical and late-onset forms of congenital adrenal hyperplasia caused by 21-OH deficiency reveal different alterations in the C4/21-OH gene region

Boehm, B. O., Rosak, C., Boehm, T. L. J., Kuehnl, P., White, P. C. & Schöffling, K., Dec 1 1986, In : Molecular Biology and Medicine. 3, 5, p. 437-448 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Frequency deletion and duplication of the steroid 21-hydroxylase genes

Werkmeister, J. W., New, M. I., Dupont, B. & White, P. C., Jan 1 1986, In : American Journal of Human Genetics. 39, 4, p. 461-469 9 p.

Research output: Contribution to journalArticle

95 Scopus citations