• 19997 Citations
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1976 …2019

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1999

Aldosterone synthase (CYP11B2) polymorphisms and cardiovascular function

White, P. C., Hautanen, A. & Kupari, M., Apr 1 1999, In : Journal of Steroid Biochemistry and Molecular Biology. 69, 1-6, p. 409-412 4 p.

Research output: Contribution to journalArticle

27 Scopus citations

Apparent cortisone reductase deficiency: A functional defect in 11β-hydroxysteroid dehydrogenase type 1

Jamieson, A., Wallace, A. M., Andrew, R., Nunez, B. S., Walker, B. R., Fraser, R., White, P. C. & Connell, J. M. C., 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 10, p. 3570-3574 5 p.

Research output: Contribution to journalArticle

Open Access
98 Scopus citations

Autosomal recessive familial neurohypophyseal diabetes insipidus with continued secretion of mutant weakly active vasopressin

Willcutts, M. D., Felner, E. & White, P. C., Jul 27 1999, In : Human molecular genetics. 8, 7, p. 1303-1307 5 p.

Research output: Contribution to journalArticle

72 Scopus citations

Expression of human kidney 11β-hydroxysteroid dehydrogenase (11-HSD2) in bacteria

Nunez, B. S., Mune, T. & White, P. C., Feb 24 1999, In : Biochemical and Biophysical Research Communications. 255, 3, p. 652-656 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Functional analysis of four CYP21 mutations from Spanish patients with congenital adrenal hyperplasia

Nunez, B. S., Lobato, M. N., White, P. C. & Meseguer, A., Sep 7 1999, In : Biochemical and Biophysical Research Communications. 262, 3, p. 635-637 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction

Hautanen, A., Toivanen, P., Mänttäri, M., Tenkanen, L., Kupari, M., Manninen, V., Kayes, K. M., Rosenfeld, S. & White, P. C., Nov 30 1999, In : Circulation. 100, 22, p. 2213-2218 6 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Mutants of 11-hydroxysteroid dehydrogenase (11-hsd2) with partial activity: Improved correlations between genotype and biochemical phenotype in apparent mineralocorticoid excess

Nunez, B. S., Rogerson, F. M., Mune, T., Igarashi, Y., Nakagawa, Y., Phillipov, G., Moudgil, A., Travis, L. B., Palermo, M., Shackleton, C. & White, P. C., Oct 1999, In : Hypertension. 34, 4, p. 638-642 5 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations

Pseudoaldosteronism and the epithelial sodium channel

Nunez, B. S. & White, P. C., Jun 23 1999, In : Current Opinion in Endocrinology and Diabetes. 6, 3, p. 238-244 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
1998

Aldosterone synthase (CYP11B2) polymorphisms and cardiovascular function

White, P. C., Hautanen, A. & Kupari, M., Jan 1 1998, In : Endocrine Research. 24, 3-4, p. 797-804 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Associations between aldosterone synthase gene polymorphism and the adrenocortical function in males

Hautanena, A., Lankinen, L., Kupari, M., Jänne, O. A., Adlercreutz, H., Nikkilä, H. & White, P. C., Jul 22 1998, In : Journal of Internal Medicine. 244, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

86 Scopus citations

Associations between human aldosterone synthase (CYP11B2) gene polymorphisms and left ventricular size, mass, and function

Kupari, M., Hautanen, A., Lankinen, L., Koskinen, P., Virolainen, J., Nikkila, H. & White, P. C., Feb 17 1998, In : Circulation. 97, 6, p. 569-575 7 p.

Research output: Contribution to journalArticle

Open Access
202 Scopus citations

Prominent sex steroid metabolism in human lymphocytes

Zhou, Z., Shackleton, C. H. L., Pahwa, S., White, P. C. & Speiser, P. W., Mar 16 1998, In : Molecular and Cellular Endocrinology. 138, 1-2, p. 61-69 9 p.

Research output: Contribution to journalArticle

52 Scopus citations
1997

11β-Hydroxysteroid dehydrogenase and its role in the syndrome of apparent mineralocorticoid excess

White, P. C., Mune, T., Rogerson, F. M., Kayes, K. M. & Agarwal, A. K., Jan 1997, In : Pediatric Research. 41, 1, p. 25-29 5 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

11β-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess

White, P. C., Mune, T. & Agarwal, A. K., Feb 24 1997, In : Endocrine reviews. 18, 1, p. 135-156 22 p.

Research output: Contribution to journalArticle

524 Scopus citations

Angiotensin II and potassium regulate human CYP11B2 transcription through common cis-elements

Clyne, C. D., Zhang, Y., Slutsker, L., Mathis, J. M., White, P. C. & Rainey, W. E., 1997, In : Molecular Endocrinology. 11, 5, p. 638-649 12 p.

Research output: Contribution to journalArticle

Open Access
172 Scopus citations

CYP11B1 mutations causing non-classic adrenal hyperplasia due to 11β- hydroxylase deficiency

Joehrer, K., Geley, S., Strasser-Wozak, E. M. C., Azziz, R., Wollmann, H. A., Schmitt, K., Kofler, R. & White, P. C., Oct 1 1997, In : Human molecular genetics. 6, 11, p. 1829-1834 6 p.

Research output: Contribution to journalArticle

93 Scopus citations

Molecular analysis of 11β-hydroxysteroid dehydrogenase and its role in the syndrome of apparent mineralocorticoid excess

White, P. C., Mune, T., Rogerson, F. M., Kayes, K. M. & Agarwal, A. K., Jan 1 1997, In : Steroids. 62, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Steroid 21-hydroxylase expression and activity in human lymphocytes

Zhou, Z., Agarwal, V. R., Dixit, N., White, P. & Speiser, P. W., Mar 14 1997, In : Molecular and Cellular Endocrinology. 127, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Variation in placental type 2 11β-hydroxysteroid dehydrogenase activity is not related to birth weight or placental weight

Rogerson, F. M., Kayes, K. M. & White, P. C., Apr 4 1997, In : Molecular and Cellular Endocrinology. 128, 1-2, p. 103-109 7 p.

Research output: Contribution to journalArticle

68 Scopus citations
1996
31 Scopus citations

Apparent mineralocorticoid excess: Genotype is correlated with biochemical phenotype

Mune, T. & White, P. C., Jan 1 1996, In : Hypertension. 27, 6, p. 1193-1199 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Calcium regulates human CYP11B2 transcription

Clyne, C. D., White, P. C. & Rainey, W. E., Jan 1 1996, In : Endocrine Research. 22, 4, p. 485-492 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

CYP11B1 mutations causing congenital adrenal hyperplasia due to 11β- hydroxylase deficiency

Geley, S., Kapelari, K., Jöhrer, K., Peter, M., Glatzl, J., Vierhapper, H., Schwarz, S., Helmberg, A., Sippell, W. G., White, P. C. & Kofler, R., Oct 8 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 8, p. 2896-2901 6 p.

Research output: Contribution to journalArticle

101 Scopus citations

Genetic disorders affecting aldosterone synthesis and action

White, P. C., Jan 1 1996, In : Current Opinion in Endocrinology and Diabetes. 3, 3, p. 220-226 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Identification of non-amplifying CYP21 genes when using PCR-based diagnosis of 21-hydroxylase deficiency in congenital adrenal hyperplasia (CAH) affected pedigrees

Day, D. J., Speiser, P. W., Schulze, E., Bettendorf, M., Fitness, J., Barany, F. & White, P. C., Dec 1 1996, In : Human molecular genetics. 5, 12, p. 2039-2048 10 p.

Research output: Contribution to journalArticle

116 Scopus citations

Inherited forms of mineralocorticoid hypertension

White, P. C., Dec 1996, In : Hypertension. 28, 6, p. 927-936 10 p.

Research output: Contribution to journalArticle

72 Scopus citations
1995

Alternatively spliced human type 1 angiotensin II receptor mRNAs are translated at different efficiencies and encode two receptor isoforms

Curnow, K. M., Pascoe, L., Davies, E., White, P. C., Corvol, P. & Clauser, E., Sep 1 1995, In : Molecular Endocrinology. 9, 9, p. 1250-1262 13 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Analysis of the human gene encoding the kidney isozyme of 11β-hydroxysteroid dehydrogenase

Agarwal, A. K., Rogerson, F. M., Mune, T. & White, P. C., Dec 1995, In : Journal of Steroid Biochemistry and Molecular Biology. 55, 5-6, p. 473-479 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Clinical, biochemical and genetic features of five extended kindred's with glucocorticoid-suppressible hyperaldosteronism

Jamieson, A., Slutsker, L., Inglis, G., Campbell, M., Fraser, R., White, P. & Connell, J., Jan 1 1995, In : Endocrine Research. 21, 1-2, p. 463-469 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cloning of cDNA encoding an NAD+-dependent isoform of 11βhydroxysteroid dehydrogenase in sheep kidney

Agarwal, A. K., Mune, T., Monder, C. & White, P. C., Jan 1 1995, In : Endocrine Research. 21, 1-2, p. 389-397 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Detection of steroid 21-hydroxylase alleles using gene-specific PCR and a multiplexed ligation detection reaction

Day, D. J., Speiser, P. W., White, P. C. & Barany, F., Sep 1 1995, In : Genomics. 29, 1, p. 152-162 11 p.

Research output: Contribution to journalArticle

105 Scopus citations

Functional studies of 11β-hydroxysteroid dehydrogenase

White, P. C., Mune, T. & Agarwal, A. K., Jan 1995, In : Steroids. 60, 1, p. 65-68 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
Open Access
144 Scopus citations

Gene structure and chromosomal localization of the human HSD11K gene encoding the kidney (Type 2) isozyme of 11β-hydroxysteroid dehydrogenase

Agarwal, A. K., Rogerson, F. M., Mune, T. & White, P. C., Sep 1 1995, In : Genomics. 29, 1, p. 195-199 5 p.

Research output: Contribution to journalArticle

106 Scopus citations

Genetic disorders of steroid hormone synthesis and metabolism

New, M. I. & White, P. C., Jul 1995, In : Bailliere's Clinical Endocrinology and Metabolism. 9, 3, p. 525-554 30 p.

Research output: Contribution to journalArticle

37 Scopus citations

Glucocorticoid-suppressible hyperaldosteronism: Effects of crossover site and parental origin of chimaeric gene on phenotypic expression

Jamieson, A., Slutsker, L., Inglis, G. C., Fraser, R., White, P. C. & Connell, J. M. C., Jan 1 1995, In : Clinical science. 88, 5, p. 563-570 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Haplotype analysis of CYP11b2

White, P. C. & Slutsker, L., Jan 1 1995, In : Endocrine Research. 21, 1-2, p. 437-442 6 p.

Research output: Contribution to journalArticle

180 Scopus citations

Human hypertension caused by mutations in the kidney isozyme of 11β–hydroxysteroid dehydrogenase

Mune, T., Rogerson, F. M., Nikkilä, H., Agarwal, A. K. & White, P. C., Aug 1995, In : Nature genetics. 10, 4, p. 394-399 6 p.

Research output: Contribution to journalArticle

559 Scopus citations
44 Scopus citations
1994

Defects in the HSD11 gene encoding 11β-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency

Nikkilä, H., Tannin, G. M., New, M. I., Taylor, N. F., Kalaitzoglou, G., Monder, C. & White, P. C., Jun 1 1994, In : Pediatric Nephrology. 8, 3, 1 p.

Research output: Contribution to journalArticle

Disorders of Steroid 1lβ-Hydroxylase Isozymes*

White, P. C., Curnow, K. M. & Pascoe, L., Aug 1994, In : Endocrine reviews. 15, 4, p. 421-438 18 p.

Research output: Contribution to journalArticle

275 Scopus citations

Genetic analysis of 11β-hydroxysteroid dehydrogenase

White, P. C., Obeid, J., Agarwal, A. K., Tannin, G. M. & Nikkila, H., Feb 1994, In : Steroids. 59, 2, p. 111-115 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Genetic diseases of steroid metabolism.

White, P. C., 1994, In : Vitamins and Hormones. 49, p. 131-195 65 p.

Research output: Contribution to journalArticle

42 Scopus citations

Molecular genetic prenatal diagnosis of congenital adrenalhyperplasia due to 21-hydroxylase deficiency by allele-specific hybridization

Speiser, P. W., White, P. C., Dupont, J., Zhu, D., Mercado, A. & New, M. I., Jan 1 1994, In : Recent progress in hormone research. 49, 1, p. 367-371 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mutations in Steroid 21‐Hydroxylase (CYP21)

White, P. C., Tusie-Luna, M. T., New, M. I. & Speiser, P. W., 1994, In : Human mutation. 3, 4, p. 373-378 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

NAD+-dependent isoform of 11β-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney

Agarwal, A. K., Mune, T., Monder, C. & White, P. C., Jan 1 1994, In : Journal of Biological Chemistry. 269, 42, p. 25959-25962 4 p.

Research output: Contribution to journalArticle

252 Scopus citations

Prenatal diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency by allele-specific hybridization and Southern blot

Speiser, P. W., White, P. C., Dupont, J., Zhu, D., Mercado, A. B. & New, M. I., Apr 1 1994, In : Human genetics. 93, 4, p. 424-428 5 p.

Research output: Contribution to journalArticle

49 Scopus citations
1993

11β-Hydroxysteroid Dehydrogenase

Monder, C. & White, P. C., Jan 1 1993, In : Vitamins and Hormones. 47, C, p. 187-271 85 p.

Research output: Contribution to journalArticle

208 Scopus citations

Defects in the HSD11 gene encoding 11 β-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency

Nikkilä, H., Tannin, G. M., New, M. I., Taylor, N. F., Kalaitzoglou, G., Monder, C. & White, P. C., Sep 1993, In : Journal of Clinical Endocrinology and Metabolism. 77, 3, p. 687-691 5 p.

Research output: Contribution to journalArticle

100 Scopus citations

Genomic organization of the mouse B-lymphocyte activation antigen B7

Selvakumar, A., White, P. C. & Dupont, B., Jun 1 1993, In : Immunogenetics. 38, 4, p. 292-295 4 p.

Research output: Contribution to journalArticle

23 Scopus citations