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Research Output 2003 2018

  • 1227 Citations
  • 14 h-Index
  • 17 Article
  • 1 Review article
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Article
2018
2 Citations (Scopus)

Author Correction: Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice

Stoodley, C. J., D’Mello, A. M., Ellegood, J., Jakkamsetti, V., Liu, P., Nebel, M. B., Gibson, J. M., Kelly, E., Meng, F., Cano, C. A., Pascual, J. M., Mostofsky, S. H., Lerch, J. P. & Tsai, P. T., Mar 16 2018, (Accepted/In press) In : Nature Neuroscience. 1 p.

Research output: Contribution to journalArticle

Autistic Disorder
8 Citations (Scopus)

Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors

Tsai, P. T., Rudolph, S., Guo, C., Ellegood, J., Gibson, J. M., Schaeffer, S. M., Mogavero, J., Lerch, J. P., Regehr, W. & Sahin, M., Oct 9 2018, In : Cell Reports. 25, 2, p. 357-367.e4

Research output: Contribution to journalArticle

Sirolimus
Autistic Disorder
Magnetic resonance imaging
Cells
Cerebellar Diseases
2017
14 Citations (Scopus)

Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy

Lipton, J. O., Boyle, L. M., Yuan, E. D., Hochstrasser, K. J., Chifamba, F. F., Nathan, A., Tsai, P. T., Davis, F. & Sahin, M., Jul 25 2017, In : Cell Reports. 20, 4, p. 868-880 13 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Sirolimus
ARNTL Transcription Factors
Clocks
Genes
48 Citations (Scopus)

Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice

Stoodley, C. J., D'Mello, A. M., Ellegood, J., Jakkamsetti, V., Liu, P., Nebel, M. B., Gibson, J. M., Kelly, E., Meng, F., Cano, C. A., Pascual, J. M., Mostofsky, S. H., Lerch, J. P. & Tsai, P. T., Dec 1 2017, In : Nature Neuroscience. 20, 12, p. 1744-1751 8 p.

Research output: Contribution to journalArticle

Autistic Disorder
Purkinje Cells
Parietal Lobe
Autism Spectrum Disorder
Social Behavior
2016
10 Citations (Scopus)

Autism and cerebellar dysfunction: Evidence from animal models

Tsai, P. T., 2016, (Accepted/In press) In : Seminars in Fetal and Neonatal Medicine.

Research output: Contribution to journalArticle

Cerebellar Diseases
Autistic Disorder
Animal Models
Autism Spectrum Disorder
Clinical Studies
7 Citations (Scopus)

Reversal of neurobehavioral social deficits in dystrophic mice using inhibitors of phosphodiesterases PDE5A and PDE9A

Alexander, M. S., Gasperini, M. J., Tsai, P. T., Gibbs, D. E., Spinazzola, J. M., Marshall, J. L., Feyder, M. J., Pletcher, M. T., Chekler, E. L. P., Morris, C. A., Sahin, M., Harms, J. F., Schmidt, C. J., Kleiman, R. J. & Kunkel, L. M., Sep 27 2016, In : Translational Psychiatry. 6, 9, e901.

Research output: Contribution to journalArticle

Dystrophin
Phosphodiesterase Inhibitors
Duchenne Muscular Dystrophy
Social Behavior
Muscles
2015
48 Citations (Scopus)

Cerebellar associative sensory learning defects in five mouse autism models

Kloth, A. D., Badura, A., Li, A., Cherskov, A., Connolly, S. G., Giovannucci, A., Bangash, M. A., Grasselli, G., Agarikano, O. P., Piochon, C., Tsai, P. T., Geschwind, D. H., Hansel, C., Sahin, M., Takumi, T., Worley, P. F. & Wang, S. S. H., Jul 9 2015, In : eLife. 4, JULY 2015, e06085.

Research output: Contribution to journalArticle

Autistic Disorder
Purkinje Cells
Learning
Defects
Gene expression
39 Citations (Scopus)

The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders

Mosconi, M. W., Wang, Z., Schmitt, L. M., Tsai, P. & Sweeney, J. A., 2015, In : Frontiers in Neuroscience. 9, SEP, 296.

Research output: Contribution to journalArticle

Cerebellum
Eye Movements
Walking
Autism Spectrum Disorder
Rodentia
2014
85 Citations (Scopus)

Copy number variation plays an important role in clinical epilepsy

Olson, H., Shen, Y., Avallone, J., Sheidley, B. R., Pinsky, R., Bergin, A. M., Berry, G. T., Duffy, F. H., Eksioglu, Y., Harris, D. J., Hisama, F. M., Ho, E., Irons, M., Jacobsen, C. M., James, P., Kothare, S., Khwaja, O., Lipton, J., Loddenkemper, T., Markowitz, J. & 24 others, Maski, K., Megerian, J. T., Neilan, E., Raffalli, P. C., Robbins, M., Roberts, A., Roe, E., Rollins, C., Sahin, M., Sarco, D., Schonwald, A., Smith, S. E., Soul, J., Stoler, J. M., Takeoka, M., Tan, W. H., Torres, A. R., Tsai, P., Urion, D. K., Weissman, L., Wolff, R., Wu, B. L., Miller, D. T. & Poduri, A., 2014, In : Annals of Neurology. 75, 6, p. 943-958 16 p.

Research output: Contribution to journalArticle

Epilepsy
International Classification of Diseases
Seizures
Trisomy
Prenatal Diagnosis
45 Citations (Scopus)

Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1

Nardo, A. D., Wertz, M. H., Kwiatkowski, E., Tsai, P. T., Leech, J. D., Greene-Colozzi, E., Goto, J., Dilsiz, P., Talos, D. M., Clish, C. B., Kwiatkowski, D. J. & Sahin, M., 2014, In : Human Molecular Genetics. 23, 14, p. 1-10 10 p., ddu101.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Autophagy
Tuberous Sclerosis
Neurons
Homeostasis
2013
16 Citations (Scopus)

A magnetic resonance imaging study of Cerebellar volume in tuberous sclerosis complex

Weisenfeld, N. I., Peters, J. M., Tsai, P. T., Prabhu, S. P., Dies, K. A., Sahin, M. & Warfield, S. K., Feb 2013, In : Pediatric Neurology. 48, 2, p. 105-110 6 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Magnetic Resonance Imaging
Cerebellum
Cognition
Mutation
24 Citations (Scopus)

Prenatal rapamycin results in early and late behavioral abnormalities in wildtype C57Bl/6 Mice

Tsai, P. T., Greene-Colozzi, E., Goto, J., Anderl, S., Kwiatkowski, D. J. & Sahin, M., Jan 2013, In : Behavior Genetics. 43, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

sclerosis
Sirolimus
abnormality
adulthood
postnatal development
2012
390 Citations (Scopus)

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

Tsai, P. T., Hull, C., Chu, Y., Greene-Colozzi, E., Sadowski, A. R., Leech, J. M., Steinberg, J., Crawley, J. N., Regehr, W. G. & Sahin, M., Aug 30 2012, In : Nature. 488, 7413, p. 647-651 5 p.

Research output: Contribution to journalArticle

Cerebellar Diseases
Purkinje Cells
Tuberous Sclerosis
Sirolimus
Cerebellum
28 Citations (Scopus)

Graded loss of tuberin in an allelic series of brain models of TSC correlates with survival, and biochemical, histological and behavioral features

Yuan, E., Tsai, P. T., Greene-colozzi, E., Sahin, M., Kwiatkowski, D. J. & Malinowska, I. A., Oct 2012, In : Human Molecular Genetics. 21, 19, p. 4286-4300 15 p., dds262.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Alleles
Survival
Brain
Neurons
2011
46 Citations (Scopus)

Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex

Tsai, P. & Sahin, M., Apr 2011, In : Current Opinion in Neurology. 24, 2, p. 106-113 8 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Cognition Disorders
Therapeutics
Phenotype
Inborn Genetic Diseases
2006
312 Citations (Scopus)

A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery

Tsai, P. T., Ohab, J. J., Kertesz, N., Groszer, M., Matter, C., Gao, J., Liu, X., Wu, H. & Carmichael, S. T., Jan 25 2006, In : Journal of Neuroscience. 26, 4, p. 1269-1274 6 p.

Research output: Contribution to journalArticle

Erythropoietin Receptors
Neurogenesis
Stroke
Erythropoietin
Lateral Ventricles
2003
86 Citations (Scopus)

BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis

Tsai, P. T., Lee, R. A. & Wu, H., Dec 1 2003, In : Blood. 102, 12, p. 3947-3953 7 p.

Research output: Contribution to journalArticle

Bone Morphogenetic Proteins
T-cells
Fibroblast Growth Factors
T-Lymphocytes
Fibroblast Growth Factor Receptors