• 7877 Citations
  • 43 h-Index
1993 …2019
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Research Output 1993 2019

  • 7877 Citations
  • 43 h-Index
  • 100 Article
  • 3 Conference contribution
  • 2 Chapter
  • 1 Comment/debate
2019

Activation of sphingosine kinase by lipopolysaccharide promotes prostate cancer cell invasion and metastasis via SphK1/S1PR4/matriptase

Lee, C. F., Dang, A., Hernandez, E., Pong, R. C., Chen, P. B., Sonavane, R., Raj, G., Kapur, P., Lin, H. Y., Wu, S. R., Ko, C. J., Lo, U. G., Lee, H. Y., Hsieh, J-T. & Lee, M. S., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

Lysosphingolipid Receptors
Lipopolysaccharides
Prostatic Neoplasms
Neoplasm Metastasis
Toll-Like Receptor 4

A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments

Kuo, C. T., Wang, J. Y., Lu, S. R., Lai, Y. S., Chang, H. H., Hsieh, J-T., Wo, A. M., Chen, P. B., Lu, J. H. & Lee, H., Dec 1 2019, In : Scientific Reports. 9, 1, 10120.

Research output: Contribution to journalArticle

Open Access
Drug Evaluation
Neoplasms
Waxes
Drug Combinations
Drug Synergism

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access
Carbamyl Phosphate
Lung Neoplasms
DNA
pyrimidine
phosphorylethanolamine

Downregulation of human DAB2IP gene expression in renal cell carcinoma results in resistance to ionizing radiation

Yun, E. J., Lin, C. J., Dang, A., Hernandez, E., Guo, J., Chen, W. M., Allison, J., Kim, N., Kapur, P., Brugarolas, J. B., Wu, K., He, D., Lai, C. H., Lin, H., Saha, D., Baek, S. T., Chen, P. B. & Hsieh, J-T., Jan 1 2019, In : Clinical Cancer Research. 25, 14, p. 4542-4551 10 p.

Research output: Contribution to journalArticle

Ionizing Radiation
Renal Cell Carcinoma
Down-Regulation
Gene Expression
Heterografts

Lysophosphatidic acid receptor LPA3 prevents oxidative stress and cellular senescence in Hutchinson–Gilford progeria syndrome

Chen, W. M., Chiang, J. C., Lin, Y. C., Lin, Y. N., Chuang, P. Y., Chang, Y. C., Chen, C. C., Wu, K. Y., Hsieh, J. C., Chen, S. K., Huang, W. P., Chen, B. P. C. & Lee, H., Jan 1 2019, (Accepted/In press) In : Aging Cell. e13064.

Research output: Contribution to journalArticle

Open Access
Lysophosphatidic Acid Receptors
Progeria
Premature Aging
Cell Aging
Oxidative Stress
3 Citations (Scopus)

Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation

Han, Y., Wu, P., Wang, Z., Zhang, Z., Sun, S., Liu, J., Gong, S., Gao, P., Iwakuma, T., Molina-Vila, M. A., Chen, P. B., Zhang, Y., Ji, T., Mo, Q., Chen, P., Hu, J., Wang, S., Zhou, J., Lu, H. & Gao, Q., Jan 1 2019, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

Cytochrome Reductases
Cytochromes
Oxidoreductases
Carcinogenesis
Degradation
2018
2 Citations (Scopus)

Facilitating tumor spheroid-based bioassays and: In vitro blood vessel modeling via bioinspired self-formation microstructure devices

Kuo, C. T., Lu, S. R., Chen, W. M., Wang, J. Y., Lee, S. C., Chang, H. H., Wo, A. M., Chen, B. P. C. & Lee, H., Jan 1 2018, In : Lab on a Chip. 18, 16, p. 2453-2465 13 p.

Research output: Contribution to journalArticle

Bioassay
Blood vessels
Biological Assay
Blood Vessels
Tumors
4 Citations (Scopus)

High Glucose Induces VEGF-C Expression via the LPA 1/3 -Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells

Huang, Y. L., Lin, Y. C., Lin, C. C., Chen, W. M., Chen, P. B. & Lee, H., Oct 1 2018, In : Cellular Physiology and Biochemistry. 50, 2, p. 612-628 17 p.

Research output: Contribution to journalArticle

Open Access
Vascular Endothelial Growth Factor C
Prostatic Neoplasms
Glucose
Hyperglycemia
Glycolysis
4 Citations (Scopus)

PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway

Lin, Y. F., Shih, H. Y., Shang, Z. F., Kuo, C. T., Guo, J., Du, C., Lee, H. & Chen, B. P. C., Feb 28 2018, In : Nucleic Acids Research. 46, 4, p. 1847-1859 13 p.

Research output: Contribution to journalArticle

DNA
S Phase Cell Cycle Checkpoints
Proteins
DNA End-Joining Repair
DNA-Activated Protein Kinase
3 Citations (Scopus)

Whole-body 12C irradiation transiently decreases mouse hippocampal dentate gyrus proliferation and immature neuron number, but does not change new neuron survival rate

Zanni, G., Deutsch, H. M., Rivera, P. D., Shih, H. Y., Leblanc, J. A., Amaral, W. Z., Lucero, M. J., Redfield, R. L., Desalle, M. J., Chen, P. B., Whoolery, C. W., Reynolds, R. P., Yun, S. & Eisch, A. J., Oct 9 2018, In : International Journal of Molecular Sciences. 19, 10, 3078.

Research output: Contribution to journalArticle

Parahippocampal Gyrus
Whole-Body Irradiation
Dentate Gyrus
Bromodeoxyuridine
neurons
2017
17 Citations (Scopus)

Androgen receptor variants mediate DNA repair after prostate cancer irradiation

Yin, Y., Li, R., Xu, K., Ding, S., Li, J., Baek, G. H., Ramanand, S. G., Ding, S., Liu, Z., Gao, Y., Kanchwala, M. S., Li, X., Hutchinson, R., Liu, X., Woldu, S. L., Xing, C., Desai, N. B., Feng, F. Y., Burma, S., De Bono, J. S. & 4 others, Dehm, S. M., Mani, R. S., Chen, B. P. C. & Raj, G. V., Sep 15 2017, In : Cancer Research. 77, 18, p. 4745-4754 10 p.

Research output: Contribution to journalArticle

Androgen Receptors
DNA Repair
Prostatic Neoplasms
Androgens
DNA Damage

A novel round bottom μ-well array chip with biomimetic nano-cilia promotes 3D tumor cultures and metastatic bioassays

Kuo, C. T., Wang, J. Y., Wo, A. M., Chen, B. P. C. & Lee, H., Jul 26 2017, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., p. 273-276 4 p. 7994041

Research output: Chapter in Book/Report/Conference proceedingConference contribution

bioassay
Bioassay
biomimetics
Biomimetics
Tumors
2 Citations (Scopus)

Coordination of the Ser2056 and Thr2609 Clusters of DNA-PKcs in Regulating Gamma Rays and Extremely Low Fluencies of Alpha-Particle Irradiation to G0/G1 Phase Cells

Nagasawa, H., Lin, Y. F., Kato, T. A., Brogan, J. R., Shih, H. Y., Kurimasa, A., Bedford, J. S., Chen, B. P. C. & Little, J. B., Feb 1 2017, In : Radiation Research. 187, 2, p. 259-267 9 p.

Research output: Contribution to journalArticle

Alpha Particles
Cell Cycle Resting Phase
Gamma Rays
G1 Phase
alpha particles
54 Citations (Scopus)

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & Deberardinis, R. J., Jun 1 2017, In : Nature. 546, 7656, p. 168-172 5 p.

Research output: Contribution to journalArticle

Carbamyl Phosphate
Ligases
Lung Neoplasms
DNA
Ammonia
1 Citation (Scopus)

Imaging of fluorescently tagged ATM kinase at the sites of DNA double strand breaks

Davis, A. J., Wang, S. Y., Chen, D. J. & Chen, B. P. C., 2017, Methods in Molecular Biology. Humana Press Inc., Vol. 1599. p. 277-285 9 p. (Methods in Molecular Biology; vol. 1599).

Research output: Chapter in Book/Report/Conference proceedingChapter

Double-Stranded DNA Breaks
DNA Repair
Lasers
Phosphotransferases
Ataxia Telangiectasia Mutated Proteins
11 Citations (Scopus)

Looping-out mechanism for resolution of replicative stress at telomeres

Zhang, T., Zhang, Z., Li, F., Hu, Q., Liu, H., Tang, M., Ma, W., Huang, J., Songyang, Z., Rong, Y., Zhang, S., Chen, B. P. & Zhao, Y., 2017, (Accepted/In press) In : EMBO Reports.

Research output: Contribution to journalArticle

Telomere
DNA
Cell Aging
Genes
Telomere Shortening
4 Citations (Scopus)

ParaStamp and Its Applications to Cell Patterning, Drug Synergy Screening, and Rewritable Devices for Droplet Storage

Kuo, C. T., Wang, J. Y., Wo, A. M., Chen, P. B. & Lee, H., May 1 2017, In : Advanced Biosystems. 1, 5, 1700048.

Research output: Contribution to journalArticle

Cytology
Preclinical Drug Evaluations
Cell Biology
Screening
Paraffin oils
15 Citations (Scopus)

Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array

Kuo, C. T., Wang, J. Y., Lin, Y. F., Wo, A. M., Chen, B. P. C. & Lee, H., Dec 1 2017, In : Scientific Reports. 7, 1, 4718.

Research output: Contribution to journalArticle

Cellular Spheroids
Biological Assay
Tumor Microenvironment
Neoplasms
Preclinical Drug Evaluations
12 Citations (Scopus)

Whole-body exposure to 28Si-radiation dose-dependently disrupts dentate gyrus neurogenesis and proliferation in the short term and new neuron survival and contextual fear conditioning in the long term

Whoolery, C. W., Walker, A. K., Richardson, D. R., Lucero, M. J., Reynolds, R. P., Beddow, D. H., Clark, K. L., Shih, H. Y., Leblanc, J. A., Cole, M. G., Amaral, W. Z., Mukherjee, S., Zhang, S., Ahn, F., Bulin, S. E., Decarolis, N. A., Rivera, P. D., Chen, B. P. C., Yun, S. & Eisch, A. J., Nov 1 2017, In : Radiation Research. 188, 5, p. 532-551 20 p.

Research output: Contribution to journalArticle

fear
Neurogenesis
Dentate Gyrus
conditioning
neurons
2016
7 Citations (Scopus)
M Phase Cell Cycle Checkpoints
Tumor Suppressor Proteins
Kinetochores
Chromosomal Instability
Microtubules
2015
14 Citations (Scopus)

DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication

Sui, J., Lin, Y. F., Xu, K., Lee, K. J., Wang, D. & Chen, B. P. C., 2015, In : Nucleic Acids Research. 43, 12, p. 5971-5983 13 p.

Research output: Contribution to journalArticle

Replication Protein A
DNA-Activated Protein Kinase
Heterogeneous-Nuclear Ribonucleoproteins
Telomere
Catalytic Domain
21 Citations (Scopus)

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress

Yang, Y., Liu, Z., Wang, F., Temviriyanukul, P., Ma, X., Tu, Y., Lv, L., Lin, Y. F., Huang, M., Zhang, T., Pei, H., Chen, B. P. C., Jansen, J. G., De Wind, N., Fischhaber, P. L., Friedberg, E. C., Tang, T. S. & Guo, C., Sep 30 2015, In : Nucleic Acids Research. 43, 17, p. 8325-8339 15 p.

Research output: Contribution to journalArticle

Homologous Recombination
DNA Damage
Lasers
Gene Conversion
Camptothecin
25 Citations (Scopus)

NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNAPKcs inhibitor

Yu, L., Shang, Z. F., Hsu, F. M., Zhang, Z., Tumati, V., Lin, Y. F., Chen, B. P. C. & Saha, D., 2015, In : Oncotarget. 6, 6, p. 3848-3860 13 p.

Research output: Contribution to journalArticle

Ionizing Radiation
Cell Death
Radiation
Autophagy
Therapeutics
6 Citations (Scopus)

Spontaneous tumor development in bone marrow-rescued DNA-PKcs3A/3A mice due to dysfunction of telomere leading strand deprotection

Zhang, S., Matsunaga, S., Lin, Y. F., Sishc, B., Shang, Z., Sui, J., Shih, H. Y., Zhao, Y., Foreman, O., Story, M. D., Chen, D. J. & Chen, B. P. C., Nov 30 2015, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Telomere
Bone Marrow
Catalytic Domain
DNA
9 Citations (Scopus)

The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry

Lee, K. J., Shang, Z. F., Lin, Y. F., Sun, J., Morotomi-Yano, K., Saha, D. & Chen, B. P. C., Apr 1 2015, In : Neoplasia. 17, 4, p. 329-338 10 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Catalytic DNA
Catalytic Domain
CDC2 Protein Kinase
Cell Cycle
62 Citations (Scopus)

Transcriptional elongation requires DNA break-induced signalling

Bunch, H., Lawney, B. P., Lin, Y. F., Asaithamby, A., Murshid, A., Wang, Y. E., Chen, B. P. C. & Calderwood, S. K., Dec 16 2015, In : Nature Communications. 6, 10191.

Research output: Contribution to journalArticle

DNA Breaks
DNA Damage
elongation
Elongation
deoxyribonucleic acid
2014
15 Citations (Scopus)

56Fe particle exposure results in a long-lasting increase in a cellular index of genomic instability and transiently suppresses adult hippocampal neurogenesis in vivo

Decarolis, N. A., Rivera, P. D., Ahn, F., Amaral, W. Z., Leblanc, J. A., Malhotra, S., Shih, H. Y., Petrik, D., Melvin, N. R., Chen, B. P. C. & Eisch, A. J., 2014, In : Life Sciences in Space Research. 2, p. 70-79 10 p.

Research output: Contribution to journalArticle

Cosmic Radiation
Genomic Instability
Neurogenesis
Nestin
genomics
8 Citations (Scopus)

Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles

Lin, Y. F., Nagasawa, H., Little, J. B., Kato, T. A., Shih, H. Y., Xie, X. J., Wilson, P. F., Brogan, J. R., Kurimasa, A., Chen, D. J., Bedford, J. S. & Chen, B. P. C., Apr 8 2014, In : PLoS One. 9, 4, e93579.

Research output: Contribution to journalArticle

Alpha Particles
Recombinational DNA Repair
Alpha particles
Radiation Tolerance
homologous recombination
132 Citations (Scopus)

DNA-PK: A dynamic enzyme in a versatile DSB repair pathway

Davis, A. J., Chen, B. P. C. & Chen, D. J., 2014, In : DNA Repair. 17, p. 21-29 9 p.

Research output: Contribution to journalArticle

Joining
Repair
Double-Stranded DNA Breaks
Genomic Instability
DNA
21 Citations (Scopus)

DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal stability

Shang, Z., Yu, L., Lin, Y. F., Matsunaga, S., Shen, C. Y. & Chen, B. P. C., 2014, In : Oncogenesis. 3, 201349.

Research output: Contribution to journalArticle

Chromosomal Instability
Mitosis
DNA
Microtubules
Spindle Apparatus
24 Citations (Scopus)

DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response

Lin, Y. F., Shih, H. Y., Shang, Z., Matsunaga, S. & Chen, B. P., 2014, In : Nucleic Acids Research. 42, 7, p. 4463-4473 11 p.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
DNA
S Phase Cell Cycle Checkpoints
Phosphorylation
Checkpoint Kinase 1
2 Citations (Scopus)

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1

Sui, J., Li, M., Qian, C., Wang, S., Cheng, Y., Chen, B. P. C. & Wang, D., Nov 3 2014, In : Drug Design, Development and Therapy. 8, p. 2147-2160 14 p.

Research output: Contribution to journalArticle

DNA-(Apurinic or Apyrimidinic Site) Lyase
Oxidation-Reduction
Colonic Neoplasms
Cytostatic Agents
Uterine Cervical Neoplasms
21 Citations (Scopus)

Selenoprotein H suppresses cellular senescence through genome maintenance and redox regulation

Wu, R. T. Y., Cao, L., Chen, B. P. C. & Cheng, W. H., Dec 5 2014, In : Journal of Biological Chemistry. 289, 49, p. 34378-34388 11 p.

Research output: Contribution to journalArticle

Selenoproteins
Cell Aging
Oxidation-Reduction
Genes
Small Interfering RNA
13 Citations (Scopus)

The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair

Li, M., Lin, Y. F., Palchik, G. A., Matsunaga, S., Wang, D. & Chen, B. P. C., 2014, In : Free Radical Biology and Medicine. 76, p. 278-285 8 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Catalytic DNA
Oxidative stress
Double-Stranded DNA Breaks
Catalytic Domain
2013
29 Citations (Scopus)

Acute and fractionated exposure to High-LET 56Fe HZE-particle radiation both result in similar long-term deficits in adult hippocampal neurogenesis

Rivera, P. D., Shih, H. Y., Leblanc, J. A., Cole, M. G., Amaral, W. Z., Mukherjee, S., Zhang, S., Lucero, M. J., Decarolis, N. A., Chen, B. P. C. & Eisch, A. J., Dec 2013, In : Radiation Research. 180, 6, p. 658-667 10 p.

Research output: Contribution to journalArticle

Cosmic Radiation
Linear Energy Transfer
Neurogenesis
stem cells
Stem Cells
64 Citations (Scopus)

A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response

Liu, H., Galka, M., Mori, E., Liu, X., Lin, Y. F., Wei, R., Pittock, P., Voss, C., Dhami, G., Li, X., Miyaji, M., Lajoie, G., Chen, B. & Li, S. C., Jun 6 2013, In : Molecular Cell. 50, 5, p. 723-735 13 p.

Research output: Contribution to journalArticle

Methylation
Lysine
DNA Damage
DNA-Activated Protein Kinase
Catalytic Domain
15 Citations (Scopus)

Effect of PF-02341066 and radiation on non-small cell lung cancer cells

Tumati, V., Kumar, S., Yu, L., Chen, B., Choy, H. & Saha, D., Mar 2013, In : Oncology Reports. 29, 3, p. 1094-1100 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Radiation
Ionizing Radiation
Radiation-Sensitizing Agents
Proteins
16 Citations (Scopus)

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination

Lee, B. S., Gapud, E. J., Zhang, S., Dorsett, Y., Bredemeyer, A., George, R., Callen, E., Daniel, J. A., Osipovich, O., Oltz, E. M., Bassing, C. H., Nussenzweig, A., Lees-Miller, S., Hammel, M., Chen, B. P. C. & Sleckman, B. P., 2013, In : Molecular and Cellular Biology. 33, 18, p. 3568-3579 12 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
V(D)J Recombination
Catalytic Domain
Phosphotransferases
Endonucleases
14 Citations (Scopus)

Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest

Singh, M., Hunt, C. R., Pandita, R. K., Kumar, R., Yang, C. R., Horikoshi, N., Bachoo, R., Serag, S., Story, M. D., Shay, J. W., Powell, S. N., Gupta, A., Jeffery, J., Pandita, S., Chen, B. P. C., Deckbar, D., Löbrich, M., Yang, Q., Khanna, K. K., Worman, H. J. & 1 others, Pandita, T. K., 2013, In : Molecular and Cellular Biology. 33, 16, p. 3390 1 p.

Research output: Contribution to journalArticle

Lamin Type A
DNA Damage
31 Citations (Scopus)

Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest

Singh, M., Hunt, C. R., Pandita, R. K., Kumar, R., Yang, C. R., Horikoshi, N., Bachoo, R., Serag, S., Story, M. D., Shay, J. W., Powell, S. N., Gupta, A., Jeffery, J., Pandita, S., Chen, B. P. C., Deckbar, D., Löbrich, M., Yang, Q., Khanna, K. K., Worman, H. J. & 1 others, Panditaa, T. K., Mar 2013, In : Molecular and Cellular Biology. 33, 6, p. 1210-1222 13 p.

Research output: Contribution to journalArticle

Lamin Type A
DNA Damage
Genomic Instability
Chromosome Aberrations
DNA Repair
22 Citations (Scopus)

Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks

Zhang, X., Lv, L., Chen, Q., Yuan, F., Zhang, T., Yang, Y., Zhang, H., Wang, Y., Jia, Y., Qian, L., Chen, B., Zhang, Y., Friedberg, E. C., Tang, T. S. & Guo, C., May 1 2013, In : DNA Repair. 12, 5, p. 377-388 12 p.

Research output: Contribution to journalArticle

DNA Breaks
DNA-Directed DNA Polymerase
Repair
DNA
Nuclear Localization Signals
33 Citations (Scopus)

Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length

Gao, P., Yoo, S. H., Lee, K. J., Rosensweig, C., Takahashi, J. S., Chen, B. P. & Green, C. B., Dec 6 2013, In : Journal of Biological Chemistry. 288, 49, p. 35277-35286 10 p.

Research output: Contribution to journalArticle

Cryptochromes
Phosphorylation
DNA-Activated Protein Kinase
DNA Repair Enzymes
Circadian Clocks

Preface

Chen, B. P. C. & Chen, D. J., Jun 1 2013, In : Translational Cancer Research. 2, 3, p. 106 1 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
DNA-Activated Protein Kinase
Catalytic DNA
Ataxia Telangiectasia
Oxidative stress
Selenium
2012
72 Citations (Scopus)

Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair

Toulany, M., Lee, K. J., Fattah, K. R., Lin, Y. F., Fehrenbacher, B., Schaller, M., Chen, B. P., Chen, D. J. & Rodemann, H. P., Jul 2012, In : Molecular Cancer Research. 10, 7, p. 945-957 13 p.

Research output: Contribution to journalArticle

Polynucleotide 5'-Hydroxyl-Kinase
Double-Stranded DNA Breaks
Protein Kinases
Catalytic Domain
Survival
13 Citations (Scopus)

A sensitive and quantitative polymerase chain reaction-based cell free in vitro non-homologous end joining assay for hematopoietic stem cells

Shao, L., Feng, W., Lee, K. J., Chen, B. P. C. & Zhou, D., Mar 20 2012, In : PLoS One. 7, 3, e33499.

Research output: Contribution to journalArticle

Polymerase chain reaction
Hematopoietic Stem Cells
Stem cells
Joining
Assays
55 Citations (Scopus)

New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress

Chen, B. P. C., Li, M. & Asaithamby, A., Dec 31 2012, In : Cancer Letters. 327, 1-2, p. 103-110 8 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Ataxia Telangiectasia
DNA Damage
Reactive Oxygen Species
Catalytic Domain
38 Citations (Scopus)

Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

Olsen, B. B., Wang, S. Y., Svenstrup, T. H., Chen, B. P. C. & Guerra, B., Mar 9 2012, In : BMC Molecular Biology. 13, 7.

Research output: Contribution to journalArticle

Casein Kinase II
Double-Stranded DNA Breaks
DNA Damage
DNA
DNA-Activated Protein Kinase
65 Citations (Scopus)

Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment

Hsu, F. M., Zhang, S. & Chen, B. P. C., Jun 1 2012, In : Translational Cancer Research. 1, 1, p. 22-34 13 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Catalytic Domain
Neoplasms
Therapeutics
Immunocompetence
25 Citations (Scopus)

Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance

Javvadi, P., Makino, H., Das, A. K., Lin, Y. F., Chen, D. J., Chen, B. P. & Nirodi, C. S., Oct 2012, In : Molecular Cancer Research. 10, 10, p. 1359-1368 10 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Threonine
Epidermal Growth Factor Receptor
Phosphorylation
Radiation