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19962019
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Research Output 1996 2019

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Article
2019
1 Citation (Scopus)
Vertebroplasty
spine
metastasis
pain
radiation therapy
6 Citations (Scopus)

Long-term Follow-up on NRG Oncology RTOG 0915 (NCCTG N0927): A Randomized Phase 2 Study Comparing 2 Stereotactic Body Radiation Therapy Schedules for Medically Inoperable Patients With Stage I Peripheral Non-Small Cell Lung Cancer

Videtic, G. M., Paulus, R., Singh, A. K., Chang, J. Y., Parker, W., Olivier, K. R., Timmerman, R., Komaki, R. R., Urbanic, J. J., Stephans, K. L., Yom, S. S., Robinson, C. G., Belani, C. P., Iyengar, P., Ajlouni, M. I., Gopaul, D. D., Gomez Suescun, J. B., McGarry, R. C., Choy, H. & Bradley, J. D., Jan 1 2019, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

schedules
Non-Small Cell Lung Carcinoma
lungs
radiation therapy
Appointments and Schedules
1 Citation (Scopus)

Multi-Institutional Validation of a Knowledge-Based Planning Model for Patients Enrolled in RTOG 0617: Implications for Plan Quality Controls in Cooperative Group Trials

Kavanaugh, J. A., Holler, S., DeWees, T. A., Robinson, C. G., Bradley, J. D., Iyengar, P., Higgins, K. A., Mutic, S. & Olsen, L. A., Jan 1 2019, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

Radiation Oncology
Quality Control
Radiotherapy
Lung
Clinical Trials
24 Citations (Scopus)

Safety and efficacy of a five-fraction stereotactic body radiotherapy schedule for centrally located non–small-cell lung cancer: NRG Oncology/RTOG 0813 trial

Bezjak, A., Paulus, R., Gaspar, L. E., Timmerman, R., Straube, W. L., Ryan, W. F., Garces, Y. I., Pu, A. T., Singh, A. K., Videtic, G. M., McGarry, R. C., Iyengar, P., Pantarotto, J. R., Urbanic, J. J., Sun, A. Y., Daly, M. E., Grills, I. S., Sperduto, P., Normolle, D. P., Bradley, J. D. & 1 others, Choy, H., May 20 2019, In : Journal of Clinical Oncology. 37, 15, p. 1316-1325 10 p.

Research output: Contribution to journalArticle

Radiosurgery
Non-Small Cell Lung Carcinoma
Appointments and Schedules
Safety
Maximum Tolerated Dose

Stereotactic Ablative Radiotherapy (SAbR) in the Setting of Metastatic Nonseminomatous Germ Cell Tumor of Testis

Satyanarayan, A., Mooney, R., Bhanvadia, R. R., Iyengar, P., Margulis, V., Desai, N. B. & Bagrodia, A., Jan 1 2019, In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Teratoma
Testicular Neoplasms
Testis
Radiotherapy
Nonseminomatous germ cell tumor
2018
4 Citations (Scopus)

Adipocyte Xbp1s overexpression drives uridine production and reduces obesity

Deng, Y., Wang, Z., Gordillo, R., Zhu, Y., Ali, A., Zhang, C., Wang, X., Shao, M., Zhang, Z., Iyengar, P., Gupta, R. K., Horton, J. D., Hill, J. A. & Scherer, P. E., Jan 1 2018, (Accepted/In press) In : Molecular Metabolism.

Research output: Contribution to journalArticle

Uridine
Adipocytes
Obesity
Lipolysis
Dihydroorotase
3 Citations (Scopus)

A pilot study using kernelled support tensor machine for distant failure prediction in lung SBRT

Li, S., Yang, N., Li, B., Zhou, Z., Hao, H., Folkert, M. R., Iyengar, P., Westover, K., Choy, H., Timmerman, R., Jiang, S. & Wang, J., Dec 1 2018, In : Medical Image Analysis. 50, p. 106-116 11 p.

Research output: Contribution to journalArticle

Radiotherapy
Non-Small Cell Lung Carcinoma
Tensors
Lung
Neoplasms
5 Citations (Scopus)

Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin

Arora, G. K., Gupta, A., Narayanan, S., Guo, T., Iyengar, P. & Infante, R. E., Jul 26 2018, In : JCI insight. 3, 14

Research output: Contribution to journalArticle

Leukemia Inhibitory Factor
Cachexia
Leptin
Lipolysis
Adipocytes
143 Citations (Scopus)
Maintenance Chemotherapy
Non-Small Cell Lung Carcinoma
Radiotherapy
Randomized Controlled Trials
Disease-Free Survival
4 Citations (Scopus)

Impact of Socioeconomic Status on Pretreatment Weight Loss and Survival in Non-Small-Cell Lung Cancer

Lau, S. K. M., Gannavarapu, B. S., Carter, K., Gao, A., Ahn, C., Meyer, J. J., Sher, D. J., Jatoi, A., Infante, R. & Iyengar, P., Apr 1 2018, In : Journal of oncology practice. 14, 4, p. e211-e220

Research output: Contribution to journalArticle

Social Class
Non-Small Cell Lung Carcinoma
Weight Loss
Survival
Neoplasms
3 Citations (Scopus)

Prevalence and Survival Impact of Pretreatment Cancer-Associated Weight Loss: A Tool for Guiding Early Palliative Care

Gannavarapu, B. S., Lau, S. K. M., Carter, K., Cannon, N. A., Gao, A., Ahn, C., Meyer, J. J., Sher, D. J., Jatoi, A., Infante, R. & Iyengar, P., Apr 1 2018, In : Journal of oncology practice. 14, 4, p. e238-e250

Research output: Contribution to journalArticle

Palliative Care
Weight Loss
Survival
Neoplasms
Cachexia
8 Citations (Scopus)

Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy

Mohamad, O., Diaz de Leon, A., Schroeder, S., Leiker, A., Christie, A., Zhang-Velten, E., Trivedi, L., Khan, S., Desai, N. B., Laine, A., Albuquerque, K., Iyengar, P., Arriaga, Y., Courtney, K., Gerber, D. E., Hammers, H., Choy, H., Timmerman, R., Brugarolas, J. & Hannan, R., Mar 10 2018, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

Radiotherapy
Safety
Disease-Free Survival
Fatigue
Melanoma
11 Citations (Scopus)
Non-Small Cell Lung Carcinoma
Uterine Cervical Neoplasms
Radiotherapy
Positron-Emission Tomography
Neoplasms
2 Citations (Scopus)

Virtual Bronchoscopy-Guided Treatment Planning to Map and Mitigate Radiation-Induced Airway Injury in Lung SAbR

Kazemzadeh, N., Modiri, A., Samanta, S., Yan, Y., Bland, R., Rozario, T., Wibowo, H., Iyengar, P., Ahn, C., Timmerman, R. & Sawant, A., Jan 1 2018, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

Lung Injury
Bronchoscopy
lungs
planning
radiation therapy
2017
5 Citations (Scopus)

A new CT reconstruction technique using adaptive deformation recovery and intensity correction (ADRIC)

Zhang, Y., Ma, J., Iyengar, P., Zhong, Y. & Wang, J., Jun 1 2017, In : Medical Physics. 44, 6, p. 2223-2241 19 p.

Research output: Contribution to journalArticle

Cone-Beam Computed Tomography
Swine
Gold
Torso
Myocardial Perfusion Imaging
176 Citations (Scopus)

Impact of intensity-modulated radiation therapy technique for locally advanced non-small-cell lung cancer: A secondary analysis of the NRG oncology RTOG 0617 randomized clinical trial

Chun, S. G., Hu, C., Choy, H., Komaki, R. U., Timmerman, R. D., Schild, S. E., Bogart, J. A., Dobelbower, M. C., Bosch, W., Galvin, J. M., Kavadi, V. S., Narayan, S., Iyengar, P., Robinson, C. G., Wynn, R. B., Raben, A., Augspurger, M. E., MacRae, R. M., Paulus, R. & Bradley, J. D., Jan 1 2017, In : Journal of Clinical Oncology. 35, 1, p. 56-62 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Radiotherapy
Randomized Controlled Trials
Pneumonia
Survival
14 Citations (Scopus)

Multi-objective radiomics model for predicting distant failure in lung SBRT

Zhou, Z., Folkert, M., Iyengar, P., Westover, K., Zhang, Y., Choy, H., Timmerman, R., Jiang, S. & Wang, J., May 8 2017, In : Physics in Medicine and Biology. 62, 11, p. 4460-4478 19 p.

Research output: Contribution to journalArticle

Radiotherapy
Lung
Area Under Curve
Non-Small Cell Lung Carcinoma
Recurrence
32 Citations (Scopus)

Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extracranial Irradiation for Extensive-Disease Small Cell Lung Cancer (ED SCLC): NRG Oncology RTOG 0937

Gore, E. M., Hu, C., Sun, A. Y., Grimm, D. F., Ramalingam, S. S., Dunlap, N. E., Higgins, K. A., Werner-Wasik, M., Allen, A. M., Iyengar, P., Videtic, G. M. M., Hales, R. K., McGarry, R. C., Urbanic, J. J., Pu, A. T., Johnstone, C. A., Stieber, V. W., Paulus, R. & Bradley, J. D., 2017, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Cranial Irradiation
Small Cell Lung Carcinoma
Survival
Neoplasm Metastasis
Confidence Intervals
2016
10 Citations (Scopus)

Inverse 4D conformal planning for lung SBRT using particle swarm optimization

Modiri, A., Gu, X., Hagan, A., Bland, R., Iyengar, P., Timmerman, R. & Sawant, A., Aug 1 2016, In : Physics in Medicine and Biology. 61, 16, p. 6181-6202 22 p.

Research output: Contribution to journalArticle

Radiotherapy
Lung
Conformal Radiotherapy
Intelligence
Non-Small Cell Lung Carcinoma
36 Citations (Scopus)
Granulocyte Colony-Stimulating Factor
Neutrophils
Radiation
Radiotherapy
Neoplasms
1 Citation (Scopus)

Obesity: Slim without the gym — the magic of chilling out

Iyengar, P. & Scherer, P. E., Feb 26 2016, (Accepted/In press) In : Nature Reviews Endocrinology.

Research output: Contribution to journalArticle

Magic
Obesity
23 Citations (Scopus)

Rationale and evidence to combine radiation therapy and immunotherapy for cancer treatment

Ishihara, D., Pop, L., Takeshima, T., Iyengar, P. & Hannan, R., Oct 14 2016, (Accepted/In press) In : Cancer Immunology, Immunotherapy. p. 1-18 18 p.

Research output: Contribution to journalArticle

Immunotherapy
Radiotherapy
Neoplasms
Therapeutics
Immune System
2015
14 Citations (Scopus)

Concurrent pemetrexed and radiation therapy in the treatment of patients with inoperable stage III non-small cell lung cancer: A systematic review of completed and ongoing studies

Choy, H., Gerber, D. E., Bradley, J. D., Iyengar, P., Monberg, M., Treat, J., Govindan, R., Koustensis, A., Barker, S. & Obasaju, C., Mar 1 2015, In : Lung Cancer. 87, 3, p. 232-240 9 p.

Research output: Contribution to journalArticle

Pemetrexed
Non-Small Cell Lung Carcinoma
Radiotherapy
Databases
Cisplatin
2 Citations (Scopus)

Driver missense mutation identification using feature selection and model fusion

Soliman, A. T., Meng, T., Chen, S. C., Iyengar, S. S., Iyengar, P., Yordy, J. & Shyu, M. L., Dec 1 2015, In : Journal of Computational Biology. 22, 12, p. 1075-1085 11 p.

Research output: Contribution to journalArticle

Feature Model
Missense Mutation
Feature Selection
Driver
Feature extraction
10 Citations (Scopus)

Employment after Radiation Oncology Residency: A Survey of the Class of 2014

Bland, R. E., Hodges, J. C., Folkert, M. R., Iyengar, P. & Meyer, J. J., Aug 1 2015, In : International Journal of Radiation Oncology Biology Physics. 92, 5, p. 969-970 2 p.

Research output: Contribution to journalArticle

Radiation Oncology
Unemployment
Internship and Residency
radiation
Surveys and Questionnaires
83 Citations (Scopus)
Non-Small Cell Lung Carcinoma
Neutrophils
Radiotherapy
Blood Platelets
Lymphocytes
13 Citations (Scopus)
Fusion Oncogene Proteins
Drug Administration Schedule
Pyrazoles
Pyridines
Cranial Irradiation
21 Citations (Scopus)

Precision hypofractionated radiation therapy in poor performing patients with non-small cell lung cancer: Phase 1 dose escalation trial

Westover, K. D., Loo, B. W., Gerber, D. E., Iyengar, P., Choy, H., Diehn, M., Hughes, R., Schiller, J., Dowell, J., Wardak, Z., Sher, D., Christie, A., Xie, X. J., Corona, I., Sharma, A., Wadsworth, M. E. & Timmerman, R., Sep 1 2015, In : International Journal of Radiation Oncology Biology Physics. 93, 1, p. 72-81 10 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
lungs
radiation therapy
Radiotherapy
cancer
20 Citations (Scopus)

Predicting distant failure in early stage NSCLC treated with SBRT using clinical parameters

Zhou, Z., Folkert, M., Cannon, N., Iyengar, P., Westover, K., Zhang, Y., Choy, H., Timmerman, R., Yan, J., Xie, X. J., Jiang, S. & Wang, J., Nov 25 2015, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Radiotherapy
Logistic Models
Area Under Curve
Sensitivity and Specificity
11 Citations (Scopus)

SABR for aggressive local therapy of metastatic cancer: A new paradigm for metastatic non-small cell lung cancer

Westover, K. D., Iyengar, P., Sharma, A. N. & Timmerman, R., Aug 1 2015, In : Lung Cancer. 89, 2, p. 87-93 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Radiotherapy
Neoplasm Metastasis
Neoplasms
Adrenal Glands
810 Citations (Scopus)

Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): A randomised, two-by-two factorial phase 3 study

Bradley, J. D., Paulus, R., Komaki, R., Masters, G., Blumenschein, G., Schild, S., Bogart, J., Hu, C., Forster, K., Magliocco, A., Kavadi, V., Garces, Y. I., Narayan, S., Iyengar, P., Robinson, C., Wynn, R. B., Koprowski, C., Meng, J., Beitler, J., Gaur, R. & 2 others, Curran, W. & Choy, H., Feb 1 2015, In : The Lancet Oncology. 16, 2, p. 187-199 13 p.

Research output: Contribution to journalArticle

Conformal Radiotherapy
Carboplatin
Paclitaxel
Non-Small Cell Lung Carcinoma
Chemoradiotherapy
2014

Message from radiation oncology special session study chair

Iyengar, P., Jul 24 2014, In : Unknown Journal. 6863906.

Research output: Contribution to journalArticle

Radiation Oncology
Oncology
Radiation
154 Citations (Scopus)

Phase II trial of stereotactic body radiation therapy combined with erlotinib for patients with limited but progressive metastatic non-small-cell lung cancer

Iyengar, P., Kavanagh, B. D., Wardak, Z., Smith, I., Ahn, C., Gerber, D. E., Dowell, J., Hughes, R., Abdulrahman, R., Camidge, D. R., Gaspar, L. E., Doebele, R. C., Bunn, P. A., Choy, H. & Timmerman, R., Dec 1 2014, In : Journal of Clinical Oncology. 32, 34, p. 3824-3830 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Radiotherapy
Disease-Free Survival
Survival
Erlotinib Hydrochloride
11 Citations (Scopus)

Stereotactic ablative body radiation therapy for tumors in the lung in octogenarians: A retrospective single institution study

Cannon, N. A., Iyengar, P., Choy, H., Timmerman, R. & Meyer, J., Dec 17 2014, In : BMC Cancer. 14, 1, 971.

Research output: Contribution to journalArticle

Radiotherapy
Lung
Neoplasms
Pneumonia
Therapeutics
Lymph Nodes
Breast Neoplasms
2013

Design of an expert system for mitigating trace element toxicity in cancer risk management

Krishna Kumar, P. T., Vinod, P. T., Phoha, V. V., Iyengar, S. S. & Iyengar, P., 2013, In : Cancer Informatics. 12, p. 21-29 9 p.

Research output: Contribution to journalArticle

Expert Systems
Risk Management
Trace Elements
Neoplasms
Diet
72 Citations (Scopus)

Histone modifications and DNA double-strand break repair after exposure to ionizing radiations

Hunt, C. R., Ramnarain, D., Horikoshi, N., Iyengar, P., Pandita, R. K., Shay, J. W. & Pandita, T. K., Apr 2013, In : Radiation Research. 179, 4, p. 383-392 10 p.

Research output: Contribution to journalArticle

Histone Code
Double-Stranded DNA Breaks
Ionizing Radiation
ionizing radiation
strands
17 Citations (Scopus)

Localization accuracy and immobilization effectiveness of a stereotactic body frame for a variety of treatment sites

Foster, R., Meyer, J., Iyengar, P., Pistenmaa, D., Timmerman, R., Choy, H. & Solberg, T., Dec 1 2013, In : International Journal of Radiation Oncology Biology Physics. 87, 5, p. 911-916 6 p.

Research output: Contribution to journalArticle

immobilization
Immobilization
pretreatment
tumors
Cone-Beam Computed Tomography
11 Citations (Scopus)

Locally advanced lung cancer: An optimal setting for vaccines and other immunotherapies

Iyengar, P. & Gerber, D. E., May 2013, In : Cancer Journal (United States). 19, 3, p. 247-262 16 p.

Research output: Contribution to journalArticle

Immunotherapy
Lung Neoplasms
Vaccines
Neoplasm Antigens
Non-Small Cell Lung Carcinoma
18 Citations (Scopus)
Non-Small Cell Lung Carcinoma
Radiotherapy
Radiation
Therapeutics
Standard of Care
21 Citations (Scopus)

The role of inflammatory pathways in cancer-associated cachexia and radiation resistance

Laine, A., Iyengar, P. & Pandita, T. K., Sep 2013, In : Molecular Cancer Research. 11, 9, p. 967-972 6 p.

Research output: Contribution to journalArticle

Cachexia
Radiation
Tumor Microenvironment
Cytokines
Neoplasms
26 Citations (Scopus)

Wavelet analysis in current cancer genome research: A survey

Meng, T., Soliman, A. T., Shyu, M. L., Yang, Y., Chen, S. C., Iyengar, S. S., Yordy, J. S. & Iyengar, P., Nov 2013, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 10, 6, p. 1442-1459 18 p., 6654125.

Research output: Contribution to journalArticle

Wavelet Analysis
Wavelet analysis
Cancer
Signal processing
Genome
2012
79 Citations (Scopus)

Isolated central nervous system progression on Crizotinib: An Achilles heel of non-small cell lung cancer with EML4-ALK translocation?

Chun, S. G., Choe, K. S., Iyengar, P., Yordy, J. S. & Timmerman, R. D., Dec 2012, In : Cancer Biology and Therapy. 13, 14, p. 1376-1383 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Central Nervous System
Survival
Gene Fusion
Biological Factors
35 Citations (Scopus)
Non-Small Cell Lung Carcinoma
Radiotherapy
Therapeutics
Radiation
Mediastinum
18 Citations (Scopus)

The value of ultrasound in detecting extra-axillary regional node involvement in patients with advanced breast cancer

Iyengar, P., Strom, E. A., Zhang, Y. J., Whitman, G. J., Smith, B. D., Woodward, W. A., Yu, T. K. & Buchholz, T. A., Nov 2012, In : Oncologist. 17, 11, p. 1402-1408 7 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Radiation
Axilla
Lymph Nodes
Mammary Ultrasonography
14 Citations (Scopus)

Toward more precise radiotherapy treatment of lung tumors

Iyengar, S., Li, X., Xu, H., Mukhopadhyay, S., Balakrishnan, N., Sawant, A. & Iyengar, P., Jan 2012, In : Computer. 45, 1, p. 59-65 7 p., 5989783.

Research output: Contribution to journalArticle

Radiotherapy
Tumors
Planning
2011

Can preoperative axillary US help exclude N2 and N3 metastatic breast cancer?

Iyengar, P. & Buchholz, T. A., 2011, In : Breast Diseases. 22, 1, p. 34-35 2 p.

Research output: Contribution to journalArticle

Breast Neoplasms
2 Citations (Scopus)

Design of a smart biomarker for bioremediation: A machine learning approach

Krishna Kumar, P. T., Vinod, P. T., Phoha, V. V., Iyengar, S. S. & Iyengar, P., Jun 2011, In : Computers in Biology and Medicine. 41, 6, p. 357-360 4 p.

Research output: Contribution to journalArticle

Mytilus
Environmental Biodegradation
Bioremediation
Trace Elements
Biomarkers
21 Citations (Scopus)

Radiation for Hodgkin's lymphoma in young female patients: A new technique to avoid the breasts and decrease the dose to the heart

Dabaja, B. S., Rebueno, N. C. S., Mazloom, A., Thorne, S., Perrin, K. J., Tolani, N., Das, P., Delclos, M. E., Iyengar, P., Reed, V. K., Horace, P. & Salehpour, M. R., Feb 1 2011, In : International Journal of Radiation Oncology Biology Physics. 79, 2, p. 503-507 5 p.

Research output: Contribution to journalArticle

Hodgkin Disease
breast
Breast
Radiation
dosage
Molecular Targeted Therapy
Radiation Oncology
Tumor Biomarkers
Antineoplastic Agents
Lung Neoplasms