• 4864 Citations
  • 26 h-Index
19962019

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Article
1996

Ribosome-initiator tRNA complex as an intermediate in translation initiation in Escherichia coli revealed by use of mutant initiator tRNAs and specialized ribosomes

Wu, X. Q., Iyengar, P. & RajBhandary, U. L., Sep 2 1996, In : EMBO Journal. 15, 17, p. 4734-4739 6 p.

Research output: Contribution to journalArticle

29 Scopus citations
2000

Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: Identification of a c-Src/Cav-1/Grb7 signaling cassette

Lee, H., Volonte, D., Galbiati, F., Iyengar, P., Lublin, D. M., Bregman, D. B., Wilson, M. T., Campos-Gonzalez, R., Bouzahzah, B., Pestell, R. G., Scherer, P. E. & Lisanti, M. P., Jan 1 2000, In : Molecular Endocrinology. 14, 11, p. 1750-1775 26 p.

Research output: Contribution to journalArticle

Open Access
275 Scopus citations
2003

Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization

Iyengar, P., Combs, T. P., Shah, S. J., Gouon-Evans, V., Pollard, J. W., Albanese, C., Flanagan, L., Tenniswood, M. P., Guha, C., Lisanti, M. P., Pestell, R. G. & Scherer, P. E., Sep 25 2003, In : Oncogene. 22, 41, p. 6408-6423 16 p.

Research output: Contribution to journalArticle

252 Scopus citations

Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin

Combs, T. P., Berg, A. H., Rajala, M. W., Klebanov, S., Iyengar, P., Jimenez-Chillaron, J. C., Patti, M. E., Klein, S. L., Weinstein, R. S. & Scherer, P. E., Feb 1 2003, In : Diabetes. 52, 2, p. 268-276 9 p.

Research output: Contribution to journalArticle

426 Scopus citations
2004

Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis. Role of INK4a/CAV-1 in mammary epithelial cell hyperplasia

Williams, T. M., Lee, H., Cheung, M. W. C., Cohen, A. W., Razani, B., Iyengar, P., Scherer, P. E., Pestell, R. G. & Lisanti, M. P., Jun 4 2004, In : Journal of Biological Chemistry. 279, 23, p. 24745-24756 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer

Hughes, K. S., Schnaper, L. A., Iyengar, P. & Buchholz, T. A., Dec 1 2004, In : Women's Oncology Review. 4, 4, p. 293-295 3 p.

Research output: Contribution to journalArticle

Role of Caveolin-1 in the Modulation of Lipolysis and Lipid Droplet Formation

Cohen, A. W., Razani, B., Schubert, W., Williams, T. M., Wang, X. B., Iyengar, P., Brasaemle, D. L., Scherer, P. E. & Lisanti, M. P., May 1 2004, In : Diabetes. 53, 5, p. 1261-1270 10 p.

Research output: Contribution to journalArticle

229 Scopus citations
2005

Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment

Iyengar, P., Espina, V., Williams, T. W., Lin, Y., Berry, D., Jelicks, L. A., Lee, H., Temple, K., Graves, R., Pollard, J., Chopra, N., Russell, R. G., Sasisekharan, R., Trock, B. J., Lippman, M., Calvert, V. S., Petricoin, E. F., Liotta, L., Dadachova, E., Pestell, R. G. & 3 others, Lisanti, M. P., Bonaldo, P. & Scherer, P. E., May 2005, In : Journal of Clinical Investigation. 115, 5, p. 1163-1176 14 p.

Research output: Contribution to journalArticle

Open Access
218 Scopus citations

Fat apoptosis through targeted activation of caspase 8: A new mouse model of inducible and reversible lipoatrophy

Pajvani, U. B., Trujillo, M. E., Combs, T. P., Iyengar, P., Jelicks, L., Roth, K. A., Kitsis, R. N. & Scherer, P. E., Jul 1 2005, In : Nature medicine. 11, 7, p. 797-803 7 p.

Research output: Contribution to journalArticle

197 Scopus citations

The hyperglycemia-induced inflammatory response in adipocytes: The role of reactive oxygen species

Lin, Y., Berg, A. H., Iyengar, P., Lam, T. K. T., Giacca, A., Combs, T. P., Rajala, M. W., Du, X., Rollman, B., Li, W., Hawkins, M., Barzilai, N., Rhodes, C. J., Fantus, I. G., Brownlee, M. & Scherer, P. E., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 4617-4626 10 p.

Research output: Contribution to journalArticle

358 Scopus citations
2006

Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell

Lara-Lemus, R., Liu, M., Turner, M. D., Scherer, P., Stenbeck, G., Iyengar, P. & Arvan, P., May 1 2006, In : Journal of cell science. 119, 9, p. 1833-1842 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2009

Metabolic dysregulation and adipose tissue fibrosis: Role of collagen VI

Khan, T., Muise, E. S., Iyengar, P., Wang, Z. V., Chandalia, M., Abate, N., Zhang, B. B., Bonaldo, P., Chua, S. & Scherer, P. E., Mar 1 2009, In : Molecular and cellular biology. 29, 6, p. 1575-1591 17 p.

Research output: Contribution to journalArticle

512 Scopus citations

Reduction of noise due to systematic uncertainties in 113mIn SPECT imaging using information theory

Krishna Kumar, P. T., Phoha, V. V., Iyengar, S. S. & Iyengar, P., May 1 2009, In : Computers in Biology and Medicine. 39, 5, p. 482-488 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2010

Clinically Apparent Internal Mammary Nodal Metastasis in Patients With Advanced Breast Cancer: Incidence and Local Control

Zhang, Y. J., Oh, J. L., Whitman, G. J., Iyengar, P., Yu, T. K., Tereffe, W., Woodward, W. A., Perkins, G., Buchholz, T. A. & Strom, E. A., Jul 15 2010, In : International Journal of Radiation Oncology Biology Physics. 77, 4, p. 1113-1119 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Hodgkin lymphoma involving extranodal and nodal head and neck sites: Characteristics and outcomes

Iyengar, P., Mazloom, A., Shihadeh, F., Berjawi, G. & Dabaja, B., Aug 15 2010, In : Cancer. 116, 16, p. 3825-3829 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Marginal zone lymphomas: Factors that affect the final outcome

Mazloom, A., Medeiros, L. J., McLaughlin, P. W., Reed, V., Cabanillas, F. F., Fayad, L. E., Pro, B., Gonzalez, G., Iyengar, P., Urbauer, D. L. & Dabaja, B. S., Sep 15 2010, In : Cancer. 116, 18, p. 4291-4298 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Outcome of patients with diffuse large B-cell lymphoma of the testis by era of treatment: The M. D. Anderson Cancer Center experience

Mazloom, A., Fowler, N., Medeiros, L. J., Iyengar, P., Horace, P. & Dabaja, B. S., Jul 1 2010, In : Leukemia and Lymphoma. 51, 7, p. 1217-1224 8 p.

Research output: Contribution to journalArticle

45 Scopus citations
2011

Design of a smart biomarker for bioremediation: A machine learning approach

Krishna Kumar, P. T., Vinod, P. T., Phoha, V. V., Iyengar, S. S. & Iyengar, P., Jun 1 2011, In : Computers in Biology and Medicine. 41, 6, p. 357-360 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Radiation for Hodgkin's lymphoma in young female patients: A new technique to avoid the breasts and decrease the dose to the heart

Dabaja, B. S., Rebueno, N. C. S., Mazloom, A., Thorne, S., Perrin, K. J., Tolani, N., Das, P., Delclos, M. E., Iyengar, P., Reed, V. K., Horace, P. & Salehpour, M. R., Feb 1 2011, In : International Journal of Radiation Oncology Biology Physics. 79, 2, p. 503-507 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Toxicity associated with postoperative radiation therapy for prostate cancer

Iyengar, P., Levy, L. B., Choi, S., Lee, A. K. & Kuban, D. A., Dec 1 2011, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 34, 6, p. 611-618 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Isolated central nervous system progression on Crizotinib: An Achilles heel of non-small cell lung cancer with EML4-ALK translocation?

Chun, S. G., Choe, K. S., Iyengar, P., Yordy, J. S. & Timmerman, R. D., Dec 1 2012, In : Cancer Biology and Therapy. 13, 14, p. 1376-1383 8 p.

Research output: Contribution to journalArticle

80 Scopus citations
36 Scopus citations

The value of ultrasound in detecting extra-axillary regional node involvement in patients with advanced breast cancer

Iyengar, P., Strom, E. A., Zhang, Y. J., Whitman, G. J., Smith, B. D., Woodward, W. A., Yu, T. K. & Buchholz, T. A., Nov 1 2012, In : Oncologist. 17, 11, p. 1402-1408 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Toward more precise radiotherapy treatment of lung tumors

Iyengar, S., Li, X., Xu, H., Mukhopadhyay, S., Balakrishnan, N., Sawant, A. & Iyengar, P., Jan 2012, In : Computer. 45, 1, p. 59-65 7 p., 5989783.

Research output: Contribution to journalArticle

14 Scopus citations
2013

Design of an expert system for mitigating trace element toxicity in cancer risk management

Krishna Kumar, P. T., Vinod, P. T., Phoha, V. V., Iyengar, S. S. & Iyengar, P., Feb 12 2013, In : Cancer Informatics. 12, p. 21-29 9 p.

Research output: Contribution to journalArticle

Localization accuracy and immobilization effectiveness of a stereotactic body frame for a variety of treatment sites

Foster, R., Meyer, J., Iyengar, P., Pistenmaa, D., Timmerman, R., Choy, H. & Solberg, T., Dec 1 2013, In : International Journal of Radiation Oncology Biology Physics. 87, 5, p. 911-916 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
18 Scopus citations

Wavelet analysis in current cancer genome research: A survey

Meng, T., Soliman, A. T., Shyu, M. L., Yang, Y., Chen, S. C., Iyengar, S. S., Yordy, J. S. & Iyengar, P., Nov 1 2013, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 10, 6, p. 1442-1459 18 p., 6654125.

Research output: Contribution to journalArticle

26 Scopus citations
2014

Phase II trial of stereotactic body radiation therapy combined with erlotinib for patients with limited but progressive metastatic non-small-cell lung cancer

Iyengar, P., Kavanagh, B. D., Wardak, Z., Smith, I., Ahn, C., Gerber, D. E., Dowell, J., Hughes, R., Abdulrahman, R., Camidge, D. R., Gaspar, L. E., Doebele, R. C., Bunn, P. A., Choy, H. & Timmerman, R., Dec 1 2014, In : Journal of Clinical Oncology. 32, 34, p. 3824-3830 7 p.

Research output: Contribution to journalArticle

160 Scopus citations

Stereotactic ablative body radiation therapy for tumors in the lung in octogenarians: A retrospective single institution study

Cannon, N. A., Iyengar, P., Choy, H., Timmerman, R. & Meyer, J., Dec 17 2014, In : BMC Cancer. 14, 1, 971.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Driver missense mutation identification using feature selection and model fusion

Soliman, A. T., Meng, T., Chen, S. C., Iyengar, S. S., Iyengar, P., Yordy, J. & Shyu, M. L., Dec 1 2015, In : Journal of Computational Biology. 22, 12, p. 1075-1085 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Employment after Radiation Oncology Residency: A Survey of the Class of 2014

Bland, R. E., Hodges, J. C., Folkert, M. R., Iyengar, P. & Meyer, J. J., Aug 1 2015, In : International Journal of Radiation Oncology Biology Physics. 92, 5, p. 969-970 2 p.

Research output: Contribution to journalArticle

10 Scopus citations
83 Scopus citations

Precision hypofractionated radiation therapy in poor performing patients with non-small cell lung cancer: Phase 1 dose escalation trial

Westover, K. D., Loo, B. W., Gerber, D. E., Iyengar, P., Choy, H., Diehn, M., Hughes, R., Schiller, J., Dowell, J., Wardak, Z., Sher, D., Christie, A., Xie, X. J., Corona, I., Sharma, A., Wadsworth, M. E. & Timmerman, R., Sep 1 2015, In : International Journal of Radiation Oncology Biology Physics. 93, 1, p. 72-81 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Predicting distant failure in early stage NSCLC treated with SBRT using clinical parameters

Zhou, Z., Folkert, M., Cannon, N., Iyengar, P., Westover, K., Zhang, Y., Choy, H., Timmerman, R., Yan, J., Xie, X. J., Jiang, S. & Wang, J., Nov 25 2015, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journalArticle

20 Scopus citations

SABR for aggressive local therapy of metastatic cancer: A new paradigm for metastatic non-small cell lung cancer

Westover, K. D., Iyengar, P., Sharma, A. N. & Timmerman, R., Aug 1 2015, In : Lung Cancer. 89, 2, p. 87-93 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): A randomised, two-by-two factorial phase 3 study

Bradley, J. D., Paulus, R., Komaki, R., Masters, G., Blumenschein, G., Schild, S., Bogart, J., Hu, C., Forster, K., Magliocco, A., Kavadi, V., Garces, Y. I., Narayan, S., Iyengar, P., Robinson, C., Wynn, R. B., Koprowski, C., Meng, J., Beitler, J., Gaur, R. & 2 others, Curran, W. & Choy, H., Feb 1 2015, In : The Lancet Oncology. 16, 2, p. 187-199 13 p.

Research output: Contribution to journalArticle

847 Scopus citations
2016

Inverse 4D conformal planning for lung SBRT using particle swarm optimization

Modiri, A., Gu, X., Hagan, A., Bland, R., Iyengar, P., Timmerman, R. & Sawant, A., Aug 1 2016, In : Physics in Medicine and Biology. 61, 16, p. 6181-6202 22 p.

Research output: Contribution to journalArticle

10 Scopus citations
38 Scopus citations

Obesity: Slim without the gym — the magic of chilling out

Iyengar, P. & Scherer, P. E., Feb 26 2016, (Accepted/In press) In : Nature Reviews Endocrinology.

Research output: Contribution to journalArticle

1 Scopus citations

Rationale and evidence to combine radiation therapy and immunotherapy for cancer treatment

Ishihara, D., Pop, L., Takeshima, T., Iyengar, P. & Hannan, R., Oct 14 2016, (Accepted/In press) In : Cancer Immunology, Immunotherapy. p. 1-18 18 p.

Research output: Contribution to journalArticle

23 Scopus citations
2017

A new CT reconstruction technique using adaptive deformation recovery and intensity correction (ADRIC)

Zhang, Y., Ma, J., Iyengar, P., Zhong, Y. & Wang, J., Jun 1 2017, In : Medical Physics. 44, 6, p. 2223-2241 19 p.

Research output: Contribution to journalArticle

5 Scopus citations

Impact of intensity-modulated radiation therapy technique for locally advanced non-small-cell lung cancer: A secondary analysis of the NRG oncology RTOG 0617 randomized clinical trial

Chun, S. G., Hu, C., Choy, H., Komaki, R. U., Timmerman, R. D., Schild, S. E., Bogart, J. A., Dobelbower, M. C., Bosch, W., Galvin, J. M., Kavadi, V. S., Narayan, S., Iyengar, P., Robinson, C. G., Wynn, R. B., Raben, A., Augspurger, M. E., MacRae, R. M., Paulus, R. & Bradley, J. D., Jan 1 2017, In : Journal of Clinical Oncology. 35, 1, p. 56-62 7 p.

Research output: Contribution to journalArticle

189 Scopus citations

Multi-objective radiomics model for predicting distant failure in lung SBRT

Zhou, Z., Folkert, M., Iyengar, P., Westover, K., Zhang, Y., Choy, H., Timmerman, R., Jiang, S. & Wang, J., May 8 2017, In : Physics in Medicine and Biology. 62, 11, p. 4460-4478 19 p.

Research output: Contribution to journalArticle

16 Scopus citations

Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extracranial Irradiation for Extensive-Disease Small Cell Lung Cancer (ED SCLC): NRG Oncology RTOG 0937

Gore, E. M., Hu, C., Sun, A. Y., Grimm, D. F., Ramalingam, S. S., Dunlap, N. E., Higgins, K. A., Werner-Wasik, M., Allen, A. M., Iyengar, P., Videtic, G. M. M., Hales, R. K., McGarry, R. C., Urbanic, J. J., Pu, A. T., Johnstone, C. A., Stieber, V. W., Paulus, R. & Bradley, J. D., 2017, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

34 Scopus citations
2018

Adipocyte Xbp1s overexpression drives uridine production and reduces obesity

Deng, Y., Wang, Z., Gordillo, R., Zhu, Y., Ali, A., Zhang, C., Wang, X., Shao, M., Zhang, Z., Iyengar, P., Gupta, R. K., Horton, J. D., Hill, J. A. & Scherer, P. E., Jan 1 2018, (Accepted/In press) In : Molecular Metabolism.

Research output: Contribution to journalArticle

7 Scopus citations

A pilot study using kernelled support tensor machine for distant failure prediction in lung SBRT

Li, S., Yang, N., Li, B., Zhou, Z., Hao, H., Folkert, M. R., Iyengar, P., Westover, K., Choy, H., Timmerman, R., Jiang, S. & Wang, J., Dec 1 2018, In : Medical Image Analysis. 50, p. 106-116 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin

Arora, G. K., Gupta, A., Narayanan, S., Guo, T., Iyengar, P. & Infante, R. E., Jul 26 2018, In : JCI insight. 3, 14

Research output: Contribution to journalArticle

5 Scopus citations
157 Scopus citations