• 2862 Citations
  • 19 h-Index
20032020

Research output per year

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Research Output

2003

Contribution of connexin26 (GJB2) mutations and founder effect to non-syndromic hearing loss in India.

RamShankar, M., Girirajan, S., Dagan, O., Ravi Shankar, H. M., Jalvi, R., Rangasayee, R., Avraham, K. B. & Anand, A., May 2003, In : Journal of medical genetics. 40, 5, p. e68

Research output: Contribution to journalArticle

Open Access
86 Scopus citations
2007

Implications in disclosing auditory genetic mutation to a family: A case study

Shekhawat, G. S., RamShankar, M., Jalvi, R. R., Rangasayee, R. & Anand, A., Jul 1 2007, In : International Journal of Audiology. 46, 7, p. 384-387 4 p.

Research output: Contribution to journalArticle

2008

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

Varambally, S., Cao, Q., Mani, R. S., Shankar, S., Wang, X., Ateeq, B., Laxman, B., Cao, X., Jing, X., Ramnarayanan, K., Brenner, J. C., Yu, J., Kim, J. H., Han, B., Tan, P., Kumar-Sinha, C., Lonigro, R. J., Palanisamy, N., Maher, C. A. & Chinnaiyan, A. M., Dec 12 2008, In : Science. 322, 5908, p. 1695-1699 5 p.

Research output: Contribution to journalArticle

818 Scopus citations

Repression of E-cadherin by the polycomb group protein EZH2 in cancer

Cao, Q., Yu, J., Dhanasekaran, S. M., Kim, J. H., Mani, R. S., Tomlins, S. A., Mehra, R., Laxman, B., Cao, X., Yu, J., Kleer, C. G., Varambally, S. & Chinnaiyan, A. M., Dec 11 2008, In : Oncogene. 27, 58, p. 7274-7284 11 p.

Research output: Contribution to journalArticle

406 Scopus citations
2009

Functional consequences of novel connexin 26 mutations associated with hereditary hearing loss

Mani, R. S., Ganapathy, A., Jalvi, R., Srikumari Srisailapathy, C. R., Malhotra, V., Chadha, S., Agarwal, A., Ramesh, A., Rangasayee, R. R. & Anand, A., Jan 1 2009, In : European Journal of Human Genetics. 17, 4, p. 502-509 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Induced chromosomal proximity and gene fusions in prostate cancer

Mani, R. S., Tomlins, S. A., Callahan, K., Ghosh, A., Nyati, M. K., Varambally, S., Palanisamy, N. & Chinnalyan, A. M., Nov 27 2009, In : Science. 326, 5957, p. 1230 1 p.

Research output: Contribution to journalShort survey

282 Scopus citations
2010

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

Yu, J., Yu, J., Mani, R. S., Cao, Q., Brenner, C. J., Cao, X., Wang, X., Wu, L., Li, J., Hu, M., Gong, Y., Cheng, H., Laxman, B., Vellaichamy, A., Shankar, S., Li, Y., Dhanasekaran, S. M., Morey, R., Barrette, T., Lonigro, R. J. & 4 others, Tomlins, S. A., Varambally, S., Qin, Z. S. & Chinnaiyan, A. M., May 18 2010, In : Cancer Cell. 17, 5, p. 443-454 12 p.

Research output: Contribution to journalArticle

531 Scopus citations

Triggers for genomic rearrangements: Insights into genomic, cellular and environmental influences

Mani, R. S. & Chinnaiyan, A. M., Dec 2010, In : Nature Reviews Genetics. 11, 12, p. 819-829 11 p.

Research output: Contribution to journalReview article

92 Scopus citations
2011

Coordinated Regulation of Polycomb Group Complexes through microRNAs in Cancer

Cao, Q., Mani, R. S., Ateeq, B., Dhanasekaran, S. M., Asangani, I. A., Prensner, J. R., Kim, J. H., Brenner, J. C., Jing, X., Cao, X., Wang, R., Li, Y., Dahiya, A., Wang, L., Pandhi, M., Lonigro, R. J., Wu, Y. M., Tomlins, S. A., Palanisamy, N., Qin, Z. & 4 others, Yu, J., Maher, C. A., Varambally, S. & Chinnaiyan, A. M., Aug 16 2011, In : Cancer Cell. 20, 2, p. 187-199 13 p.

Research output: Contribution to journalArticle

160 Scopus citations

The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma

Banerjee, R., Mani, R. S., Russo, N., Scanlon, C. S., Tsodikov, A., Jing, X., Cao, Q., Palanisamy, N., Metwally, T., Inglehart, R. C., Tomlins, S., Bradford, C., Carey, T., Wolf, G., Kalyana-Sundaram, S., Chinnaiyan, A. M., Varambally, S. & D'Silva, N. J., Oct 20 2011, In : Oncogene. 30, 42, p. 4339-4349 11 p.

Research output: Contribution to journalArticle

74 Scopus citations

TMPRSS2-ERG-mediated feed-forward regulation of wild-type ERG in human prostate cancers

Mani, R. S., Iyer, M. K., Cao, Q., Brenner, J. C., Wang, L., Ghosh, A., Cao, X., Lonigro, R. J., Tomlins, S. A., Varambally, S. & Chinnaiyan, A. M., Aug 15 2011, In : Cancer research. 71, 16, p. 5387-5392 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
2012

Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells

He, S., Wang, J., Kato, K., Xie, F., Varambally, S., Mineishi, S., Kuick, R., Mochizuki, K., Liu, Y., Nieves, E., Mani, R. S., Chinnaiyan, A. M., Marquez, V. E. & Zhang, Y., Feb 2 2012, In : Blood. 119, 5, p. 1274-1282 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Role of transcriptional corepressor CtBP1 in prostate cancer progression

Wang, R., Asangani, I. A., Chakravarthi, B. V. S. K., Ateeq, B., Lonigro, R. J., Cao, Q., Mani, R. S., Camacho, D. F., McGregor, N., Schumann, T. E. W., Jing, X., Menawat, R., Tomlins, S. A., Zheng, H., Otte, A. P., Mehra, R., Siddiqui, J., Dhanasekaran, S. M., Nyati, M. K., Pienta, K. J. & 5 others, Palanisamy, N., Kunju, L. P., Rubin, M. A., Chinnaiyan, A. M. & Varambally, S., Oct 2012, In : Neoplasia (United States). 14, 10, p. 905-914 10 p.

Research output: Contribution to journalArticle

43 Scopus citations
2013

The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease

He, S., Xie, F., Liu, Y., Tong, Q., Mochizuki, K., Lapinski, P. E., Mani, R. S., Reddy, P., Mochizuki, I., Chinnaiyan, A. M., Mineishi, S., King, P. D. & Zhang, Y., 2013, In : Blood. 122, 25, p. 4119-4128 10 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations
2014

The emerging role of speckle-type POZ protein (SPOP) in cancer development

Mani, R. S., Sep 2014, In : Drug Discovery Today. 19, 9, p. 1498-1502 5 p.

Research output: Contribution to journalReview article

40 Scopus citations

TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer

Banerjee, R., Russo, N., Liu, M., Basrur, V., Bellile, E., Palanisamy, N., Scanlon, C. S., Van Tubergen, E., Inglehart, R. C., Metwally, T., Mani, R. S., Yocum, A., Nyati, M. K., Castilho, R. M., Varambally, S., Chinnaiyan, A. M. & D'Silva, N. J., Jul 31 2014, In : Nature communications. 5, 4527.

Research output: Contribution to journalArticle

60 Scopus citations
2016

Erratum: TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer (Nature Communications (2014) 5 (4527) DOI: 10.1038/ncomms5527)

Banerjee, R., Russo, N., Liu, M., Basrur, V., Bellile, E., Palanisamy, N., Scanlon, C. S., Van Tubergen, E., Inglehart, R. C., Metwally, T., Mani, R. S., Yocum, A., Nyati, M. K., Castilho, R. M., Varambally, S., Chinnaiyan, A. M. & D'Silva, N. J., Feb 24 2016, In : Nature Communications. 7, 10726.

Research output: Contribution to journalArticle

Functional Analysis of a Novel Connexin30 Mutation in a Large Family with Hearing Loss, Pesplanus, Ichthyosis, Cutaneous Nodules, and Keratoderma

Pandey, N., Xavier, D. F., Chatterjee, A., Mani, R. S., Hiremagalore, R., Tharakan, A., Rajashekhar, B. & Anand, A., Jan 1 2016, In : Annals of Human Genetics. 80, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

Inflammation-Induced Oxidative Stress Mediates Gene Fusion Formation in Prostate Cancer

Mani, R. S., Amin, M. A., Li, X., Kalyana-Sundaram, S., Veeneman, B. A., Wang, L., Ghosh, A., Aslam, A., Ramanand, S. G., Rabquer, B. J., Kimura, W., Tran, M., Cao, X., Roychowdhury, S., Dhanasekaran, S. M., Palanisamy, N., Sadek, H. A., Kapur, P., Koch, A. E. & Chinnaiyan, A. M., Dec 6 2016, In : Cell Reports. 17, 10, p. 2620-2631 12 p.

Research output: Contribution to journalArticle

32 Scopus citations
2017

Androgen receptor variants mediate DNA repair after prostate cancer irradiation

Yin, Y., Li, R., Xu, K., Ding, S., Li, J., Baek, G. H., Ramanand, S. G., Ding, S., Liu, Z., Gao, Y., Kanchwala, M. S., Li, X., Hutchinson, R., Liu, X., Woldu, S. L., Xing, C., Desai, N. B., Feng, F. Y., Burma, S., De Bono, J. S. & 4 others, Dehm, S. M., Mani, R. S., Chen, B. P. C. & Raj, G. V., Sep 15 2017, In : Cancer research. 77, 18, p. 4745-4754 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2018

BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer

Li, X., Baek, G. H., Ramanand, S. G., Sharp, A., Gao, Y., Yuan, W., Welti, J., Rodrigues, D. N., Dolling, D., Figueiredo, I., Sumanasuriya, S., Crespo, M., Aslam, A., Li, R., Yin, Y., Mukherjee, B., Kanchwala, M., Hughes, A. M., Halsey, W. S., Chiang, C. M. & 5 others, Xing, C., Raj, G. V., Burma, S., de Bono, J. & Mani, R. S., Jan 16 2018, In : Cell Reports. 22, 3, p. 796-808 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Targeting Bromodomain and Extra-Terminal (BET) family proteins in Castration-Resistant Prostate Cancer (CRPC)

International SU2C/PCF Prostate Cancer Dream Team, Jul 1 2018, In : Clinical Cancer Research. 24, 13, p. 3149-3162 14 p.

Research output: Contribution to journalArticle

28 Scopus citations
2019

Genetic, Environmental, and Nuclear Factors Governing Genomic Rearrangements

Ramanand, S. G. & Mani, R. S., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer, p. 57-66 10 p. (Advances in Experimental Medicine and Biology; vol. 1210).

Research output: Chapter in Book/Report/Conference proceedingChapter

Genome-wide germline correlates of the epigenetic landscape of prostate cancer

Houlahan, K. E., Shiah, Y. J., Gusev, A., Yuan, J., Ahmed, M., Shetty, A., Ramanand, S. G., Yao, C. Q., Bell, C., O’Connor, E., Huang, V., Fraser, M., Heisler, L. E., Livingstone, J., Yamaguchi, T. N., Rouette, A., Foucal, A., Espiritu, S. M. G., Sinha, A., Sam, M. & 23 others, Timms, L., Johns, J., Wong, A., Murison, A., Orain, M., Picard, V., Hovington, H., Bergeron, A., Lacombe, L., Lupien, M., Fradet, Y., Têtu, B., McPherson, J. D., Pasaniuc, B., Kislinger, T., Chua, M. L. K., Pomerantz, M. M., van der Kwast, T., Freedman, M. L., Mani, R. S., He, H. H., Bristow, R. G. & Boutros, P. C., Oct 1 2019, In : Nature medicine. 25, 10, p. 1615-1626 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2020

Prostate carcinogenesis: inflammatory storms

de Bono, J. S., Guo, C., Gurel, B., De Marzo, A. M., Sfanos, K. S., Mani, R. S., Gil, J., Drake, C. G. & Alimonti, A., Aug 1 2020, In : Nature Reviews Cancer. 20, 8, p. 455-469 15 p.

Research output: Contribution to journalReview article

The landscape of RNA polymerase II–associated chromatin interactions in prostate cancer

Ramanand, S. G., Chen, Y., Yuan, J., Daescu, K., Lambros, M. B. K., Houlahan, K. E., Carreira, S., Yuan, W., Baek, G. H., Sharp, A., Paschalis, A., Kanchwala, M., Gao, Y., Aslam, A., Safdar, N., Zhan, X., Raj, G. V., Xing, C., Boutros, P. C., de Bono, J. & 2 others, Zhang, M. Q. & Mani, R. S., Aug 3 2020, In : Journal of Clinical Investigation. 140, 8, p. 3987-4005 19 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations