Renee M McKay

  • 3120 Citations
  • 19 h-Index
19992019

Research output per year

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Research Output

  • 3120 Citations
  • 19 h-Index
  • 26 Article
  • 1 Book
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Article
2019
Open Access
6 Scopus citations
2017

Modeling renal cell carcinoma in mice: Bap1 and Pbrm1 inactivation drive tumor grade

Gu, Y. F., Cohn, S., Christie, A., McKenzie, T., Wolff, N., Do, Q. N., Madhuranthakam, A. J., Pedrosa, I., Wang, T., Dey, A., Busslinger, M., Xie, X-J., Hammer, R. E., McKay, R. M., Kapur, P. & Brugarolas, J. B., 2017, In : Cancer Discovery. 7, 8, p. 900-917 18 p.

Research output: Contribution to journalArticle

32 Scopus citations
2016

Targeting renal cell carcinoma with a HIF-2 antagonist

Chen, W., Hill, H., Christie, A., Kim, M. S., Holloman, E., Pavia-Jimenez, A., Homayoun, F., Ma, Y., Patel, N., Yell, P., Hao, G., Yousuf, Q., Joyce, A., Pedrosa, I., Geiger, H., Zhang, H., Chang, J., Gardner, K. H., Bruick, R. K., Reeves, C. & 14 others, Hwang, T. H., Courtney, K., Frenkel, E., Sun, X., Zojwalla, N., Wong, T., Rizzi, J. P., Wallace, E. M., Josey, J. A., Xie, Y., Xie, X. J., Kapur, P., McKay, R. M. & Brugarolas, J., 2016, In : Nature. 539, 7627, p. 112-117 6 p.

Research output: Contribution to journalArticle

193 Scopus citations
2015

High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma

Wolff, N. C., Pavía-Jiménez, A., Tcheuyap, V. T., Alexander, S., Vishwanath, M., Christie, A., Xie, X. J., Williams, N. S., Kapur, P., Posner, B., McKay, R. M. & Brugarolas, J., 2015, In : Oncotarget. 6, 19, p. 16951-16962 12 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Analysis of Fmr1 deletion in a subpopulation of post-mitotic neurons in mouse cortex and hippocampus

Amiri, A., Sanchez-Ortiz, E., Cho, W., Birnbaum, S. G., Xu, J., Mckay, R. M. & Parada, L. F., Feb 2014, In : Autism Research. 7, 1, p. 60-71 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

Wang, S. S., Gu, Y. F., Wolff, N., Stefanius, K., Christie, A., Dey, A., Hammer, R. E., Xie, X-J., Rakheja, D., Pedrosa, I., Carroll, T. J., McKay, R. M., Kapur, P. & Brugarolas, J. B., Nov 18 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 46, p. 16538-16543 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors

Chau, V., Lim, S. K., Mo, W., Liu, C., Patel, A. J., McKay, R. M., Wei, S., Posner, B. A., De Brabander, J. K., Williams, N. S., Parada, L. F. & Le, L. Q., Jan 15 2014, In : Cancer Research. 74, 2, p. 586-597 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

REDD1/DDIT4-independent mTORC1 inhibition and apoptosis by glucocorticoids in thymocytes

Wolff, N. C., McKay, R. M. & Brugarolas, J., 2014, In : Molecular Cancer Research. 12, 6, p. 867-877 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2013

CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors

Mo, W., Chen, J., Patel, A., Zhang, L., Chau, V., Li, Y., Cho, W., Lim, K., Xu, J., Lazar, A. J., Creighton, C. J., Bolshakov, S., McKay, R. M., Lev, D., Le, L. Q. & Parada, L. F., Feb 28 2013, In : Cell. 152, 5, p. 1077-1090 14 p.

Research output: Contribution to journalArticle

94 Scopus citations
2012

A restricted cell population propagates glioblastoma growth after chemotherapy

Chen, J., Li, Y., Yu, T. S., McKay, R. M., Burns, D. K., Kernie, S. G. & Parada, L. F., Aug 23 2012, In : Nature. 488, 7412, p. 522-526 5 p.

Research output: Contribution to journalArticle

1096 Scopus citations

Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development

Li, Y., Yui, D., Luikart, B. W., McKay, R. M., Li, Y., Rubenstein, J. L. & Parada, L. F., Sep 18 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 38, p. 15491-15496 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Literature search and review

Chen, J., Li, Y., Yu, T. S., McKay, R. M., Burns, D. K., Kernie, S. G. & Parada, L. F., Oct 1 2012, In : Assay and Drug Development Technologies. 10, 5, p. 403-405 3 p.

Research output: Contribution to journalArticle

Malignant glioma: Lessons from genomics, mouse models, and stem cells

Chen, J., McKay, R. M. & Parada, L. F., Mar 30 2012, In : Cell. 149, 1, p. 36-47 12 p.

Research output: Contribution to journalArticle

305 Scopus citations

Neurofibromin Modulates Adult hippocampal neurogenesis and behavioral effects of antidepressants

Li, Y., Li, Y., McKay, R. M., Riethmacher, D. & Parada, L. F., Mar 7 2012, In : Journal of Neuroscience. 32, 10, p. 3529-3539 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis

Amiri, A., Cho, W., Zhou, J., Birnbaum, S. G., Sinton, C. M., McKay, R. M. & Parada, L. F., Apr 25 2012, In : Journal of Neuroscience. 32, 17, p. 5880-5890 11 p.

Research output: Contribution to journalArticle

102 Scopus citations

Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake

Zeve, D., Seo, J., Suh, J. M., Stenesen, D., Tang, W., Berglund, E. D., Wan, Y., Williams, L. J., Lim, A., Martinez, M. J., McKay, R. M., Millay, D. P., Olson, E. N. & Graff, J. M., Apr 4 2012, In : Cell Metabolism. 15, 4, p. 492-504 13 p.

Research output: Contribution to journalArticle

40 Scopus citations
2011

Glioblastoma multiforme: A perspective on recent findings in human cancer and mouse models

Lim, S. K., Llaguno, S. R. A., McKay, R. M. & Parada, L. F., Mar 2011, In : BMB Reports. 44, 3, p. 158-164 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle

Zhou, J., Shrikhande, G., Xu, J., Mckay, R. M., Burns, D. K., Johnson, J. E. & Parada, L. F., Aug 1 2011, In : Genes and Development. 25, 15, p. 1595-1600 6 p.

Research output: Contribution to journalArticle

70 Scopus citations
2007

Adipose Is a Conserved Dosage-Sensitive Antiobesity Gene

Suh, J. M., Zeve, D., McKay, R., Seo, J., Salo, Z., Li, R., Wang, M. & Graff, J. M., Sep 5 2007, In : Cell Metabolism. 6, 3, p. 195-207 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

Tripeptidyl peptidase II promotes fat formation in a conserved fashion

McKay, R. M., McKay, J. P., Suh, J. M., Avery, L. & Graff, J. M., Dec 2007, In : EMBO Reports. 8, 12, p. 1183-1189 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
2006

Hedgehog signaling plays a conserved role in inhibiting fat formation

Suh, J. M., Gao, X., McKay, J., McKay, R., Salo, Z. & Graff, J. M., Jan 2006, In : Cell Metabolism. 3, 1, p. 25-34 10 p.

Research output: Contribution to journalArticle

157 Scopus citations
2003

C. elegans: A model for exploring the genetics of fat storage

McKay, R. M., McKay, J. P., Avery, L. & Graff, J. M., Jan 1 2003, In : Developmental Cell. 4, 1, p. 131-142 12 p.

Research output: Contribution to journalArticle

210 Scopus citations
2002

Smad10 is required for formation of the frog nervous system

LeSueur, J. A., Fortuno, E. S., McKay, R. M. & Graff, J. M., 2002, In : Developmental Cell. 2, 6, p. 771-783 13 p.

Research output: Contribution to journalArticle

17 Scopus citations
2001

The casein kinase I family: Roles in morphogenesis

McKay, R. M., Peters, J. M. & Graff, J. M., Jul 15 2001, In : Developmental Biology. 235, 2, p. 378-387 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

The casein kinase I family in Wnt signaling

McKay, R. M., Peters, J. M. & Graff, J. M., Jul 15 2001, In : Developmental Biology. 235, 2, p. 388-396 9 p.

Research output: Contribution to journalArticle

95 Scopus citations
1999

Casein kinase I transduces Wnt signals

Peters, J. M., McKay, R. M., McKay, J. P. & Graff, J. M., Sep 23 1999, In : Nature. 401, 6751, p. 345-350 6 p.

Research output: Contribution to journalArticle

354 Scopus citations