• 8087 Citations
  • 33 h-Index
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Fingerprint Dive into the research topics where Richard K Bruick is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Hypoxia-Inducible Factor 1 Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Oxygen Medicine & Life Sciences
Iron Medicine & Life Sciences
Prolyl Hydroxylases Medicine & Life Sciences
Hemerythrin Medicine & Life Sciences
Alpha Subunit Hypoxia-Inducible Factor 1 Medicine & Life Sciences
Homeostasis Medicine & Life Sciences

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Research Output 1996 2018

  • 8087 Citations
  • 33 h-Index
  • 48 Article
  • 1 Conference contribution
  • 1 Review article
1 Citation (Scopus)

Modulation of HIF-2α PAS-B domain contributes to physiological responses

Feng, Z., Zou, X., Chen, Y., Wang, H., Duan, Y. & Bruick, R. K., Dec 26 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. 13240-13245 6 p.

Research output: Contribution to journalArticle

High Fat Diet
Body Weight
Hypoxia-Inducible Factor 1
3 Citations (Scopus)
Peptic Esophagitis
Gastroesophageal Reflux
7 Citations (Scopus)

Hypoxia-inducible factor-2α plays a role in mediating oesophagitis in GORD

Huo, X., Agoston, A. T., Dunbar, K. B., Cipher, D. J., Zhang, X., Yu, C., Cheng, E., Zhang, Q., Pham, T. H., Tambar, U. K., Bruick, R. K., Wang, D. H., Odze, R. D., Spechler, S. J. & Souza, R. F., Sep 30 2016, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

Peptic Esophagitis
Bile Acids and Salts
Cell Movement
Epithelial Cells
117 Citations (Scopus)

On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models

Cho, H., Du, X., Rizzi, J. P., Liberzon, E., Chakraborty, A. A., Gao, W., Carvo, I., Signoretti, S., Bruick, R. K., Josey, J. A., Wallace, E. M. & Kaelin, W. G., 2016, In : Nature. 539, 7627, p. 107-111 5 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Renal Cell Carcinoma
Tumor Suppressor Proteins
Transcription Factors
19 Citations (Scopus)

Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling

Ding, M., Bruick, R. K. & Yu, Y., Feb 25 2016, In : Nature Cell Biology. 18, 3, p. 319-327 9 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor I
Growth Factor Receptors
Extracellular Space