• 1282 Citations
  • 15 h-Index
20012019

Research output per year

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Research Output

  • 1282 Citations
  • 15 h-Index
  • 30 Article
  • 2 Review article
2019

Cellular signalling by primary cilia in development, organ function and disease

Anvarian, Z., Mykytyn, K., Mukhopadhyay, S., Pedersen, L. B. & Christensen, S. T., Apr 1 2019, In : Nature Reviews Nephrology. 15, 4, p. 199-219 21 p.

Research output: Contribution to journalReview article

17 Scopus citations

Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities

Shimada, I. S., Somatilaka, B. N., Hwang, S. H., Anderson, A. G., Shelton, J. M., Rajaram, V., Konopka, G. & Mukhopadhyay, S., Jun 1 2019, In : Developmental Biology. 450, 1, p. 47-62 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dominant negative GPR161 rare variants are risk factors of human spina bifida

Kim, S. E., Lei, Y., Hwang, S. H., Wlodarczyk, B. J., Mukhopadhyay, S., Shaw, G. M., Ross, M. E. & Finnell, R. H., Jan 15 2019, In : Human Molecular Genetics. 28, 2, p. 200-208 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia

Hwang, S. H., Somatilaka, B. N., Badgandi, H., Palicharla, V. R., Walker, R., Shelton, J. M., Qian, F. & Mukhopadhyay, S., Mar 4 2019, In : Current Biology. 29, 5, p. 790-802.e5

Research output: Contribution to journalArticle

3 Scopus citations
2018

Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis

Shimada, I. S., Hwang, S. H., Somatilaka, B. N., Wang, X., Skowron, P., Kim, J., Kim, M., Shelton, J. M., Rajaram, V., Xuan, Z., Taylor, M. D. & Mukhopadhyay, S., Jan 30 2018, In : Cell Reports. 22, 5, p. 1169-1184 16 p.

Research output: Contribution to journalArticle

14 Scopus citations

The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner

Hwang, S. H., White, K. A., Somatilaka, B. N., Shelton, J. M., Richardson, J. A. & Mukhopadhyay, S., Jan 1 2018, In : Development (Cambridge). 145, 1, dev154054.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Trafficking to the primary cilium membrane

Mukhopadhyay, S., Badgandi, H. B., Hwang, S. H., Somatilaka, B., Shimada, I. S. & Pal, K., Jan 15 2017, In : Molecular Biology of the Cell. 28, 2, p. 233-239 7 p.

Research output: Contribution to journalReview article

15 Scopus citations

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins

Badgandi, H. B., Hwang, S. H., Shimada, I. S., Loriot, E. & Mukhopadhyay, S., Mar 6 2017, In : The Journal of cell biology. 216, 3, p. 743-760 18 p.

Research output: Contribution to journalArticle

36 Scopus citations

Using primary neurosphere cultures to study primary cilia

Shimada, I. S., Badgandi, H., Somatilaka, B. N. & Mukhopadhyay, S., Apr 14 2017, In : Journal of Visualized Experiments. 2017, 122, e55315.

Research output: Contribution to journalArticle

1 Scopus citations
2016

G-protein-coupled receptor signaling and neural tube closure defects

Shimada, I. S. & Mukhopadhyay, S., 2016, (Accepted/In press) In : Birth Defects Research Part A - Clinical and Molecular Teratology.

Research output: Contribution to journalArticle

1 Scopus citations

Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium

Pal, K., Hwang, S. H., Somatilaka, B., Badgandi, H., Jackson, P. K., DeFea, K. & Mukhopadhyay, S., Mar 28 2016, In : Journal of Cell Biology. 212, 7, p. 861-875 15 p.

Research output: Contribution to journalArticle

42 Scopus citations
2015
8 Scopus citations

Primary cilium and sonic hedgehog signaling during neural tube patterning: Role of GPCRs and second messengers

Pal, K. & Mukhopadhyay, S., Apr 1 2015, In : Developmental Neurobiology. 75, 4, p. 337-348 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
6 Scopus citations

TCTEX1D2, a potential link to skeletal ciliopathies

Mukhopadhyay, S., Feb 1 2015, In : Cell Cycle. 14, 3, p. 293-294 2 p.

Research output: Contribution to journalArticle

1 Scopus citations
2014

G-protein-coupled receptors, hedgehog signaling and primary cilia

Mukhopadhyay, S. & Rohatgi, R., 2014, In : Seminars in Cell and Developmental Biology. 33, p. 63-72 10 p.

Research output: Contribution to journalArticle

76 Scopus citations
2013

Cilia, tubby mice, and obesity

Mukhopadhyay, S. & Jackson, P. K., Jan 2013, In : Cilia. 2, 1, 1.

Research output: Contribution to journalArticle

6 Scopus citations

The ciliary G-protein-coupled receptor Gpr161 negatively regulates the sonic hedgehog pathway via cAMP signaling

Mukhopadhyay, S., Wen, X., Ratti, N., Loktev, A., Rangell, L., Scales, S. J. & Jackson, P. K., Jan 7 2013, In : Cell. 152, 1-2, p. 210-223 14 p.

Research output: Contribution to journalArticle

184 Scopus citations
2011

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

Wright, K. J., Baye, L. M., Olivier-Mason, A., Mukhopadhyay, S., Sang, L., Kwong, M., Wang, W., Pretorius, P. R., Sheffield, V. C., Sengupta, P., Slusarski, D. C. & Jackson, P. K., Nov 15 2011, In : Genes and Development. 25, 22, p. 2347-2360 14 p.

Research output: Contribution to journalArticle

128 Scopus citations

The tubby family proteins

Mukhopadhyay, S. & Jackson, P. K., Jun 28 2011, In : Genome Biology. 12, 6, 225.

Research output: Contribution to journalArticle

51 Scopus citations
2010

TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia

Mukhopadhyay, S., Wen, X., Chih, B., Nelson, C. D., Lane, W. S., Scales, S. J. & Jackson, P. K., Oct 1 2010, In : Genes and Development. 24, 19, p. 2180-2193 14 p.

Research output: Contribution to journalArticle

181 Scopus citations
2009

Cis-regulatory mechanisms of gene expression in an olfactory neuron type in Caenorhabditis elegans

Nokes, E. B., Van Der Linden, A. M., Winslow, C., Mukhopadhyay, S., Ma, K. & Sengupta, P., Dec 2009, In : Developmental Dynamics. 238, 12, p. 3080-3092 13 p.

Research output: Contribution to journalArticle

14 Scopus citations
2008

Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8

Omori, Y., Zhao, C., Saras, A., Mukhopadhyay, S., Kim, W., Furukawa, T., Sengupta, P., Veraksa, A. & Malicki, J., 2008, In : Nature Cell Biology. 10, 4, p. 437-444 8 p.

Research output: Contribution to journalArticle

145 Scopus citations

Sensory Signaling-Dependent Remodeling of Olfactory Cilia Architecture in C. elegans

Mukhopadhyay, S., Lu, Y., Shaham, S. & Sengupta, P., May 13 2008, In : Developmental Cell. 14, 5, p. 762-774 13 p.

Research output: Contribution to journalArticle

83 Scopus citations
2007

Distinct IFT mechanisms contribute to the generation of ciliary structural diversity in C. elegans

Mukhopadhyay, S., Lu, Y., Qin, H., Lanjuin, A., Shaham, S. & Sengupta, P., Jun 20 2007, In : EMBO Journal. 26, 12, p. 2966-2980 15 p.

Research output: Contribution to journalArticle

67 Scopus citations
2004

Identification of thermosensory and olfactory neuron-specific genes via expression profiling of single neuron types

Colosimo, M. E., Brown, A., Mukhopadhyay, S., Gabel, C., Lanjuin, A. E., Samuel, A. D. T. & Sengupta, P., Dec 29 2004, In : Current Biology. 14, 24, p. 2245-2251 7 p.

Research output: Contribution to journalArticle

85 Scopus citations

Platelet storage under in vitro condition is associated with calcium-dependent apoptosis-like lesions and novel reorganization in platelet cytoskeleton

Wadhawan, V., Karim, Z. A., Mukhopadhyay, S., Gupta, R., Dikshit, M. & Dash, D., Feb 15 2004, In : Archives of Biochemistry and Biophysics. 422, 2, p. 183-190 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
9 Scopus citations
2002

Factor VIII gene polymorphisms in North Indian population: A consensus algorithm for carrier analysis of hemophilia A

Srinivasan, A., Mukhopadhyay, S., Karim, Z. A., Gupta, R. K., Gupta, A., Wadhawan, V., Shukla, J., Singh, V. P. & Dash, D., Nov 2002, In : Clinica Chimica Acta. 325, 1-2, p. 177-181 5 p.

Research output: Contribution to journalArticle

14 Scopus citations
6 Scopus citations
2001

Bruton's tyrosine kinase associates with the actin-based cytoskeleton in activated platelets

Mukhopadhyay, S., Ramars, A. S. S. & Dash, D., 2001, In : Journal of Cellular Biochemistry. 81, 4, p. 659-665 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Bruton's tyrosine kinase is a substrate of calpain in human platelets

Mukhopadhyay, S., Ramars, A. S. S., Ochs, H. D. & Dash, D., Sep 7 2001, In : FEBS Letters. 505, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

9 Scopus citations