If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Samuel McBrayer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Histone Demethylases Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Lipogenesis Medicine & Life Sciences
Fibrosarcoma Medicine & Life Sciences
NADP Medicine & Life Sciences
Nucleosides Medicine & Life Sciences
Homeostasis Medicine & Life Sciences
Multiple Myeloma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2009 2019

  • 253 Citations
  • 7 h-Index
  • 12 Article
  • 1 Comment/debate
  • 1 Review article
10 Citations (Scopus)

Cells lacking the RB1 tumor suppressor gene are hyperdependent on aurora B kinase for survival

Oser, M. G., Fonseca, R., Chakraborty, A. A., Brough, R., Spektor, A., Jennings, R. B., Flaifel, A., Novak, J. S., Gulati, A., Buss, E., Younger, S. T., McBrayer, S. K., Cowley, G. S., Bonal, D. M., Nguyen, Q. D., Brulle-Soumare, L., Taylor, P., Cairo, S., Ryan, C. J., Pease, E. J. & 9 others, Maratea, K., Travers, J., Root, D. E., Signoretti, S., Pellman, D., Ashton, S., Lord, C. J., Barry, S. T. & Kaelin, W. G., Jan 1 2019, In : Cancer discovery. 9, 2, p. 230-247 18 p.

Research output: Contribution to journalArticle

Aurora Kinase B
Small Cell Lung Carcinoma
Tumor Suppressor Genes
Clustered Regularly Interspaced Short Palindromic Repeats
E2F Transcription Factors
5 Citations (Scopus)

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

Harris, I. S., Endress, J. E., Coloff, J. L., Selfors, L. M., McBrayer, S. K., Rosenbluth, J. M., Takahashi, N., Dhakal, S., Koduri, V., Oser, M. G., Schauer, N. J., Doherty, L. M., Hong, A. L., Kang, Y. P., Younger, S. T., Doench, J. G., Hahn, W. C., Buhrlage, S. J., DeNicola, G. M., Kaelin, W. G. & 1 others, Brugge, J. S., May 7 2019, In : Cell Metabolism. 29, 5, p. 1166-1181.e6

Research output: Contribution to journalArticle

Glutathione
Cell Survival
Homeostasis
Neoplasms
Proteins
17 Citations (Scopus)

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate

Chakraborty, A. A., Laukka, T., Myllykoski, M., Ringel, A. E., Booker, M. A., Tolstorukov, M. Y., Meng, Y. J., Meier, S. R., Jennings, R. B., Creech, A. L., Herbert, Z. T., McBrayer, S. K., Olenchock, B. A., Jaffe, J. D., Haigis, M. C., Beroukhim, R., Signoretti, S., Koivunen, P. & Kaelin, W. G., Jan 1 2019, In : Science. 363, 6432, p. 1217-1222 6 p.

Research output: Contribution to journalArticle

Histone Demethylases
Chromatin
Oxygen
Methylation
Histones

Peptidic degron for IMiD-induced degradation of heterologous proteins

Koduri, V., McBrayer, S. K., Liberzon, E., Wang, A. C., Briggs, K. J., Cho, H. & Kaelin, W. G., Feb 12 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 7, p. 2539-2544 6 p.

Research output: Contribution to journalArticle

Open Access
Proteolysis
Proteins
Thalidomide
Ligases
Ubiquitin
2 Citations (Scopus)

Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase

McBrayer, S. K., Olenchock, B. A., DiNatale, G. J., Shi, D. D., Khanal, J., Jennings, R. B., Novak, J. S., Oser, M. G., Robbins, A. K., Modiste, R., Bonal, D., Moslehi, J., Bronson, R. T., Neuberg, D., Nguyen, Q. D., Signoretti, S., Losman, J. A. & Kaelin, W. G., Apr 17 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 16, p. E3741-E3748

Research output: Contribution to journalArticle

Open Access
Histone Demethylases
Neoplasms
Growth
Retinoblastoma-Binding Protein 2
Carcinogenesis