• 662 Citations
  • 14 h-Index
20072017
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Research Output 2007 2017

  • 662 Citations
  • 14 h-Index
  • 22 Article
2017
94 Citations (Scopus)

cGAS is essential for the antitumor effect of immune checkpoint blockade

Wang, H., Hu, S., Chen, X., Shi, H., Chen, C., Sun, L. & Chen, Z. J., Feb 14 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 7, p. 1637-1642 6 p.

Research output: Contribution to journalArticle

Adenosine Monophosphate
Cross-Priming
Interferon Type I
Experimental Melanomas
Antibodies
2015
9 Citations (Scopus)

Gallic acid is the major active component of cortex moutan in inhibiting immune maturation of human monocyte-derived dendritic cells

Chan, B. C. L., Li, L. F., Hu, S. Q., Wat, E., Wong, E. C. W., Zhang, V. X., Lau, C. B. S., Wong, C. K., Hon, K. L. E., Hui, P. C. L. & Leung, P. C., Sep 1 2015, In : Molecules. 20, 9, p. 16388-16403 16 p.

Research output: Contribution to journalArticle

monocytes
Gallic Acid
cortexes
Dendritic Cells
Monocytes
9 Citations (Scopus)

Inhibition of EZH2 expression is associated with the proliferation, apoptosis, and migration of SW620 colorectal cancer cells in vitro

He, S. B., Zhou, H., Zhou, J., Zhou, G. Q., Han, T., Wan, D. W., Gu, W., Gao, L., Zhang, Y., Xue, X. F., Zhang, L. F., Fei, M., Hu, S. Q., Yang, X. D., Zhu, X. G., Wang, L. & Li, D. C., Jan 1 2015, In : Experimental Biology and Medicine. 240, 4, p. 458-466 9 p.

Research output: Contribution to journalArticle

Gene expression
Colorectal Neoplasms
Genes
Cells
Apoptosis

Simultaneous pancreas and kidney transplantation for liver transplant recipients with diabetes and uremia

Tam, N., Zhang, C., Lin, J., Wu, C., Deng, R., Liao, B., Hu, S., Wang, D., Zhu, X., Wu, L. & He, X., Jan 1 2015, In : Clinics and Research in Hepatology and Gastroenterology. 39, 3, p. 399-404 6 p.

Research output: Contribution to journalArticle

Pancreas Transplantation
Uremia
Kidney Transplantation
Liver
Transplants
50 Citations (Scopus)

The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense

Hu, S., Peng, L., Kwak, Y. T., Tekippe, E. M., Pasare, C., Malter, J. S., Hooper, L. V. & Zaki, M. H., Apr 3 2015, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

Inflammasomes
Interleukin-18
Homeostasis
Escherichia coli
DNA
2014
12 Citations (Scopus)

Effect of CLN3 silencing by RNA interference on the proliferation and apoptosis of human colorectal cancer cells

Zhu, X., Huang, Z., Chen, Y., Zhou, J., Hu, S., Zhi, Q., Song, S., Wang, Y., Wan, D., Gu, W., Zhou, H., Zhang, B., Cao, W. & He, S., Jan 1 2014, In : Biomedicine and Pharmacotherapy. 68, 3, p. 253-258 6 p.

Research output: Contribution to journalArticle

RNA Interference
Colorectal Neoplasms
Apoptosis
Small Interfering RNA
HCT116 Cells
32 Citations (Scopus)

Expression of Lgr5, a marker of intestinal stem cells, in colorectal cancer and its clinicopathological significance

He, S., Zhou, H., Zhu, X., Hu, S., Fei, M., Wan, D., Gu, W., Yang, X., Shi, D., Zhou, J., Zhou, J., Zhu, Z., Wang, L., Li, D. & Zhang, Y., Jan 1 2014, In : Biomedicine and Pharmacotherapy. 68, 5, p. 507-513 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Stem Cells
Catenins
Wnt Signaling Pathway
Neoplastic Stem Cells
2013
34 Citations (Scopus)

Anti-inflammatory and anti-allergic activities of pentaherb formula, moutan cortex (Danpi) and gallic acid

Liu, K. Y. P., Hu, S., Chan, B. C. L., Wat, E. C. L., Lau, C. B. S., Hon, K. L., Fung, K. P., Leung, P. C., Hui, P. C. L., Lam, C. W. K. & Wong, C. K., Mar 1 2013, In : Molecules. 18, 3, p. 2483-2500 18 p.

Research output: Contribution to journalArticle

Anti-Allergic Agents
Gallic Acid
cortexes
Anti-Inflammatory Agents
acids
17 Citations (Scopus)

MicroRNA-21 * regulates the prosurvival effect of GM-CSF on human eosinophils

Wong, C. K., Lau, K. M., Chan, I. H. S., Hu, S., Lam, Y. Y. O., Choi, A. O. K. & Lam, C. W. K., Feb 1 2013, In : Immunobiology. 218, 2, p. 255-262 8 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
MicroRNAs
Eosinophils
Extracellular Signal-Regulated MAP Kinases
Apoptosis
16 Citations (Scopus)

Muramyl dipeptide mediated activation of human bronchial epithelial cells interacting with basophils: A novel mechanism of airway inflammation

Qiu, H. N., Wong, C. K., Chu, I. M. T., Hu, S. & Lam, C. W. K., Apr 1 2013, In : Clinical and Experimental Immunology. 172, 1, p. 81-94 14 p.

Research output: Contribution to journalArticle

Acetylmuramyl-Alanyl-Isoglutamine
Basophils
Epithelial Cells
Inflammation
Nucleotides
21 Citations (Scopus)

NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: A link between innate immunity and allergic asthma

Wong, C. K., Hu, S., Leung, K. M. L., Dong, J., He, L., Chu, Y. J., Chu, I. M. T., Qiu, H. N., Liu, K. Y. P. & Lam, C. W. K., Jul 1 2013, In : Cellular and Molecular Immunology. 10, 4, p. 317-329 13 p.

Research output: Contribution to journalArticle

Eosinophils
Innate Immunity
Asthma
Nucleotides
Epithelial Cells
20 Citations (Scopus)

Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation

Sun, Z., Hu, S., Luo, Q., Ye, D., Hu, D. & Chen, F., May 1 2013, In : Oncology Reports. 29, 5, p. 1701-1706 6 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Ubiquitin
Reactive Oxygen Species
Post Translational Protein Processing
Mucous Membrane
2012
11 Citations (Scopus)

Activation of Toll-like receptor 3 induces apoptosis of oral squamous carcinoma cells in vitro and in vivo

Luo, Q., Hu, S., Yan, M., Sun, Z., Chen, W. & Chen, F., Aug 1 2012, In : International Journal of Biochemistry and Cell Biology. 44, 8, p. 1266-1275 10 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 3
Squamous Cell Carcinoma
Chemical activation
Apoptosis
Toll-Like Receptors
55 Citations (Scopus)

In vitro and in vivo anti-tumor effect of metformin as a novel therapeutic agent in human oral squamous cell carcinoma

Luo, Q., Hu, D., Hu, S., Yan, M., Sun, Z. & Chen, F., Nov 14 2012, In : BMC Cancer. 12, 517.

Research output: Contribution to journalArticle

Metformin
Squamous Cell Carcinoma
Neoplasms
Therapeutics
Cyclin D1
28 Citations (Scopus)

Structural characterization and immuno-modulating activities of a polysaccharide from Ganoderma sinense

Han, X. Q., Chan, B. C. L., Yu, H., Yang, Y. H., Hu, S. Q., Ko, C. H., Dong, C. X., Wong, C. K., Shaw, P. C., Fung, K. P., Leung, P. C., Hsiao, W. L., Tu, P. F. & Han, Q. B., Nov 1 2012, In : International Journal of Biological Macromolecules. 51, 4, p. 597-603 7 p.

Research output: Contribution to journalArticle

Ganoderma
Polysaccharides
Blood Cells
Blood
Tumor Necrosis Factor-alpha
19 Citations (Scopus)

The pharmacological NF-κB inhibitor BAY11-7082 induces cell apoptosis and inhibits the migration of human uveal melanoma cells

Hu, S., Luo, Q., Cun, B., Hu, D., Ge, S., Fan, X. & Chen, F., Jan 1 2012, In : International Journal of Molecular Sciences. 13, 12, p. 15653-15667 15 p.

Research output: Contribution to journalArticle

apoptosis
Cell death
inhibitors
Pharmacology
Apoptosis
2011
14 Citations (Scopus)

Activation of eosinophils by IL-12 family cytokine IL-27: Implications of the pleiotropic roles of IL-27 in allergic responses

Hu, S., Wong, C. K. & Lam, C. W. K., Jan 1 2011, In : Immunobiology. 216, 1-2, p. 54-65 12 p.

Research output: Contribution to journalArticle

Interleukin-27
Interleukin-12
Eosinophils
Cytokines
Lipopolysaccharides
2010
61 Citations (Scopus)

Activation of human eosinophils and epidermal keratinocytes by Th2 cytokine IL-31: Implication for the immunopathogenesis of atopic dermatitis

Cheung, P. F. Y., Wong, C. K., Ho, A. W. Y., Hu, S., Chen, D. P. & Lam, C. W. K., Apr 21 2010, In : International Immunology. 22, 6, p. 453-467 15 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Keratinocytes
Eosinophils
Cytokines
Coculture Techniques
118 Citations (Scopus)

Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: Implications in allergic inflammation

Wong, C. K., Hu, S., Cheung, P. F. Y. & Lam, C. W. K., Sep 1 2010, In : American Journal of Respiratory Cell and Molecular Biology. 43, 3, p. 305-315 11 p.

Research output: Contribution to journalArticle

Eosinophils
Inflammation
Flow cytometry
Adhesion
Flow Cytometry
2009
32 Citations (Scopus)

Activation of peripheral Th17 lymphocytes in patients with asthma

Wong, C. K., Lun, S. W. M., Ko, F. W. S., Wong, P. T. Y., Hu, S. Q., Chan, I. H. S., Hui, D. S. C. & Lam, C. W. K., Nov 9 2009, In : Immunological Investigations. 38, 7, p. 652-664 13 p.

Research output: Contribution to journalArticle

Interleukin-17
Asthma
Lymphocytes
Th17 Cells
Interleukin-23
2007
9 Citations (Scopus)

DRB Genotyping in Cynomolgus Monkeys from China Using Polymerase Chain Reaction -Sequence-Specific Primers

Wei, H., Wang, H., Hou, S., Hu, S., Fan, K., Fan, X., Zhu, T. & Guo, Y., Feb 1 2007, In : Human Immunology. 68, 2, p. 135-144 10 p.

Research output: Contribution to journalArticle

Dichlororibofuranosylbenzimidazole
Macaca fascicularis
China
Polymerase Chain Reaction
Alleles
1 Citation (Scopus)

Functional and stable expression of recombinant human FOXP3 in bacterial cells and development of antigen-specific monoclonal antibodies

Hu, S., Dai, J., Wei, H., Fan, K., Wang, H., Zhang, D., Qian, W., Li, B., Wang, H., Zhu, T., Zhang, Y. & Guo, Y., Oct 1 2007, In : Journal of Biochemistry. 142, 4, p. 471-480 10 p.

Research output: Contribution to journalArticle

Glutathione Transferase
Monoclonal Antibodies
Antigens
Proteins
Recombinant Proteins