• 2704 Citations
  • 26 h-Index
1986 …2019

Research output per year

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Research Output

  • 2704 Citations
  • 26 h-Index
  • 57 Article
  • 1 Comment/debate
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Article
2019

Family still matters: Counseling patients with complex family histories of colon and endometrial cancers

Gemmell, A. P., Mauer, C. B., Reys, B. D., Pirzadeh-Miller, S. & Ross, T. S., Sep 1 2019, In : Molecular Genetics and Genomic Medicine. 7, 9, e886.

Research output: Contribution to journalArticle

Open Access

Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis

Holmstrom, S. R., Wijayatunge, R., McCrum, K., Mgbemena, V. E. & Ross, T. S., Sep 27 2019, In : iScience. 19, p. 809-820 12 p.

Research output: Contribution to journalArticle

Open Access

SCGN deficiency results in colitis susceptibility

Sifuentes-Dominguez, L., Li, H., Llano, E., Liu, Z., Singla, A., Patel, A. S., Kathania, M., Khoury, A., Norris, N., Rios, J. J., Starokadomskyy, P., Park, J. Y., Gopal, P., Liu, Q., Tan, S., Chan, L., Ross, T., Harrison, S., K, V., Baker, L. A. & 2 others, Jia, D. & Burstein, E., Oct 2019, In : eLife. 8, e49910.

Research output: Contribution to journalArticle

Open Access
2018

Deficiency of the Endocytic Protein Hip1 Leads to Decreased Gdpd3 Expression, Low Phosphocholine, and Kypholordosis

Wijayatunge, R., Holmstrom, S. R., Foley, S. B., Mgbemena, V. E., Bhargava, V., Perez, G. L., McCrum, K. & Ross, T. S., Dec 1 2018, In : Molecular and Cellular Biology. 38, 23

Research output: Contribution to journalArticle

Hormone replacement therapy after oophorectomy and breast cancer risk among BRCA1 mutation carriers

Hereditary Breast Cancer Clinical Study Group, Aug 1 2018, In : JAMA oncology. 4, 8, p. 1059-1065 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Prevalence of variant reclassification following hereditary cancer genetic testing

Mersch, J., Brown, N., Pirzadeh-Miller, S., Mundt, E., Cox, H. C., Brown, K., Aston, M., Esterling, L., Manley, S. & Ross, T., Sep 25 2018, In : JAMA - Journal of the American Medical Association. 320, 12, p. 1266-1274 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

The association between smoking and cancer incidence in BRCA1 and BRCA2 mutation carriers

the Hereditary Breast Cancer Clinical Study Group, Jun 1 2018, In : International Journal of Cancer. 142, 11, p. 2263-2272 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

TumorNext-Lynch-MMR: A comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome

Gray, P. N., Tsai, P., Chen, D., Wu, S., Hoo, J., Mu, W., Li, B., Vuong, H., Lu, H. M., Batth, N., Willett, S., Uyeda, L., Shah, S., Gau, C. L., Umali, M., Espenschied, C., Janicek, M., Brown, S., Margileth, D., Dobrea, L. & 9 others, Wagman, L., Rana, H., Hall, M. J., Ross, T., Terdiman, J., Cullinane, C., Ries, S., Totten, E. & Elliott, A. M., Apr 17 2018, In : Oncotarget. 9, 29, p. 20304-20322 19 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function

Mgbemena, V. E., Signer, R. A. J., Wijayatunge, R., Laxson, T., Morrison, S. J. & Ross, T. S., Jan 24 2017, In : Cell Reports. 18, 4, p. 947-960 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolic gatekeeper function of B-lymphoid transcription factors

Chan, L. N., Chen, Z., Braas, D., Lee, J. W., Xiao, G., Geng, H., Cosgun, K. N., Hurtz, C., Shojaee, S., Cazzaniga, V., Schjerven, H., Ernst, T., Hochhaus, A., Kornblau, S. M., Konopleva, M., Pufall, M. A., Cazzaniga, G., Liu, G. J., Milne, T. A., Koeffler, H. P. & 7 others, Ross, T. S., Sánchez-García, I., Borkhardt, A., Yamamoto, K. R., Dickins, R. A., Graeber, T. G. & Müschen, M., Feb 23 2017, In : Nature. 542, 7642, p. 479-483 5 p.

Research output: Contribution to journalArticle

49 Scopus citations
2016

Genetic Counseling Assistants: an Integral Piece of the Evolving Genetic Counseling Service Delivery Model

Pirzadeh-Miller, S., Robinson, L. S., Read, P. & Ross, T. S., Nov 10 2016, (Accepted/In press) In : Journal of Genetic Counseling. p. 1-12 12 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis

Tang, H., Sebti, S., Titone, R., Zhou, Y., Isidoro, C., Ross, T. S., Hibshoosh, H., Xiao, G., Packer, M., Xie, Y. & Levine, B., Mar 1 2015, In : EBioMedicine. 2, 3, p. 255-263 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Prediction of Cancer Prevention: From Mammogram Screening to Identification of BRCA1/2 Mutation Carriers in Underserved Populations

Robinson, L. S., Hendrix, A., Xie, X. J., Yan, J., Pirzadeh-Miller, S., Pritzlaff, M., Read, P., Pass, S., Euhus, D. & Ross, T. S., Nov 1 2015, In : EBioMedicine. 2, 11, p. 1827-1833 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Use of panel tests in place of single gene tests in the cancer genetics clinic

Yorczyk, A., Robinson, L. S. & Ross, T. S., Sep 1 2015, In : Clinical Genetics. 88, 3, p. 278-282 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic

Foley, S. B., Rios, J. J., Mgbemena, V. E., Robinson, L. S., Hampel, H. L., Toland, A. E., Durham, L. & Ross, T. S., 2015, In : EBioMedicine. 2, 1, p. 74-81 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
2014

An Internal Performance Assessment of CancerGene Connect: An Electronic Tool to Streamline, Measure and Improve the Genetic Counseling Process

Pritzlaff, M., Yorczyk, A., Robinson, L. S., Pirzadeh-Miller, S., Lin, T., Euhus, D. & Ross, T. S., Nov 16 2014, In : Journal of Genetic Counseling. 23, 6, p. 1034-1044 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits

Messa, M., Fernández-Busnadiego, R., Sun, E. W., Chen, H., Czapla, H., Wrasman, K., Wu, Y., Ko, G., Ross, T., Wendland, B. & De Camilli, P., 2014, In : eLife. 3, p. e03311

Research output: Contribution to journalArticle

47 Scopus citations

Re-evaluating the role of BCR/ABL in chronic myelogenous leukemia

Ross, T. S. & Mgbemena, V. E., Sep 15 2014, In : Molecular and Cellular Oncology. 1, 3, e963450.

Research output: Contribution to journalArticle

10 Scopus citations
2013

Analysis of induced pluripotent stem cells from a BRCA1 mutant family

Soyombo, A. A., Wu, Y., Kolski, L., Rios, J. J., Rakheja, D., Chen, A., Kehler, J., Hampel, H., Coughran, A. & Ross, T. S., Oct 15 2013, In : Stem Cell Reports. 1, 4, p. 336-349 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Expression of BCR/ABL p210 from a Knockin Allele Enhances Bone Marrow Engraftment without Inducing Neoplasia

Foley, S. B., Hildenbrand, Z. L., Soyombo, A. A., Magee, J. A., Wu, Y., Oravecz-Wilson, K. I. & Ross, T. S., Oct 17 2013, In : Cell Reports. 5, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
2012

Grace Rock's consent

Ross, T. S., Aug 2012, In : Endocrine-Related Cancer. 19, 4

Research output: Contribution to journalArticle

1 Scopus citations
2011

Huntingtin-interacting protein 1: A merkel cell carcinoma marker that interacts with c-Kit

Ames, H. M., Bichakjian, C. K., Liu, G. Y., Oravecz-Wilson, K. I., Fullen, D. R., Verhaegen, M. E., Johnson, T. M., Dlugosz, A. A. & Ross, T. S., Oct 2011, In : Journal of Investigative Dermatology. 131, 10, p. 2113-2120 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2009

Persistence of Leukemia-Initiating Cells in a Conditional Knockin Model of an Imatinib-Responsive Myeloproliferative Disorder

Oravecz-Wilson, K. I., Philips, S. T., Yilmaz, Ö. H., Ames, H. M., Li, L., Crawford, B. D., Gauvin, A. M., Lucas, P. C., Sitwala, K., Downing, J. R., Morrison, S. J. & Ross, T. S., Aug 4 2009, In : Cancer Cell. 16, 2, p. 137-148 12 p.

Research output: Contribution to journalArticle

52 Scopus citations
2008

Hip 1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice

Jain, R. N., Al-Menhali, A. A., Keeley, T. M., Ren, J., El-Zaatari, M., Chen, X., Merchant, J. L., Ross, T. S., Chew, C. S. & Samuelson, L. C., Jul 1 2008, In : Journal of Clinical Investigation. 118, 7, p. 2459-2470 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Use of a cryptic splice site for the expression of huntingtin interacting protein 1 in select normal and neoplastic tissues

Graves, C. W., Philips, S. T., Bradley, S. V., Oravecz-Wilson, K. I., Li, L., Gauvin, A. & Ross, T. S., Feb 15 2008, In : Cancer Research. 68, 4, p. 1064-1073 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2007

Aberrant huntingtin interacting protein 1 in lymphoid malignancies

Bradley, S. V., Smith, M. R., Hyun, T. S., Lucas, P. C., Li, L., Antonuk, D., Joshi, I., Jin, F. & Ross, T. S., Sep 15 2007, In : Cancer Research. 67, 18, p. 8923-8931 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1

Bradley, S. V., Hyun, T. S., Oravecz-Wilson, K. I., Li, L., Waldorff, E. I., Ermilov, A. N., Goldstein, S. A., Zhang, C. X., Drubin, D. G., Varela, K., Parlow, A., Dlugosz, A. A. & Ross, T. S., Jun 2007, In : Human Molecular Genetics. 16, 11, p. 1279-1292 14 p.

Research output: Contribution to journalArticle

31 Scopus citations

Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor

Bradley, S. V., Holland, E. C., Liu, G. Y., Thomas, D., Hyun, T. S. & Ross, T. S., Apr 15 2007, In : Cancer Research. 67, 8, p. 3609-3615 7 p.

Research output: Contribution to journalArticle

38 Scopus citations
2005

Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors

Mills, I. G., Gaughan, L., Robson, C., Ross, T., McCracken, S., Kelly, J. & Neal, D. E., Jul 2005, In : Journal of Cell Biology. 170, 2, p. 191-200 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

Serum antibodies to Huntingtin interacting protein-1: A new blood test for prostate cancer

Bradley, S. V., Oravecz-Wilson, K. I., Bougeard, G., Mizukami, I., Li, L., Munaco, A. J., Sreekumar, A., Corradetti, M. N., Chinnaiyan, A. M., Sanda, M. G. & Ross, T. S., May 15 2005, In : Cancer Research. 65, 10, p. 4126-4133 8 p.

Research output: Contribution to journalArticle

47 Scopus citations
2004

HIP1: Trafficking roles and regulation of tumorigenesis

Hyun, T. S. & Ross, T. S., Apr 1 2004, In : Trends in Molecular Medicine. 10, 4, p. 194-199 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

HIP1 and HIP1r Stabilize Receptor Tyrosine Kinases and Bind 3-Phosphoinositides Via Epsin N-terminal Homology Domains

Hyun, T. S., Rao, D. S., Saint-Dic, D., Michael, L. E., Kumar, P. D., Bradley, S. V., Mizukami, I. F., Oravecz-Wilson, K. I. & Ross, T. S., Apr 2 2004, In : Journal of Biological Chemistry. 279, 14, p. 14294-14306 13 p.

Research output: Contribution to journalArticle

55 Scopus citations

Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1

Hyun, T. S., Li, L., Oravecz-Wilson, K. I., Bradley, S. V., Provot, M. M., Munaco, A. J., Mizukami, I. F., Sun, H. & Ross, T. S., May 2004, In : Molecular and Cellular Biology. 24, 10, p. 4329-4340 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Huntingtin Interacting Protein 1 mutations lead to abnormal hematopoiesis, spinal defects and cataracts

Oravecz-Wilson, K. I., Kiel, M. J., Li, L., Rao, D. S., Saint-Dic, D., Kumar, P. D., Provot, M. M., Hankenson, K. D., Reddy, V. N., Lieberman, A. P., Morisson, S. J. & Ross, T. S., Apr 15 2004, In : Human Molecular Genetics. 13, 8, p. 851-867 17 p.

Research output: Contribution to journalArticle

26 Scopus citations
2003

Altered receptor trafficking in Huntingtin Interacting Protein 1-transformed cells

Rao, D. S., Bradley, S. V., Kumar, P. D., Hyun, T. S., Saint-Dic, D., Oravecz-Wilson, K., Kleer, C. G. & Ross, T. S., May 2003, In : Cancer Cell. 3, 5, p. 471-482 12 p.

Research output: Contribution to journalArticle

76 Scopus citations
2002

Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival

Rao, D. S., Hyun, T. S., Kumar, P. D., Mizukami, I. F., Rubin, M. A., Lucas, P. C., Sanda, M. G. & Ross, T. S., 2002, In : Journal of Clinical Investigation. 110, 3, p. 351-360 10 p.

Research output: Contribution to journalArticle

80 Scopus citations
2001

Clathrin- and AP-2-binding Sites in HIP1 Uncover a General Assembly Role for Endocytic Accessory Proteins

Mishra, S. K., Agostinelli, N. R., Brett, T. J., Mizukami, I., Ross, T. S. & Traub, L. M., Dec 7 2001, In : Journal of Biological Chemistry. 276, 49, p. 46230-46236 7 p.

Research output: Contribution to journalArticle

103 Scopus citations

Huntingtin interacting protein 1 is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors

Rao, D. S., Chang, J. C., Kumar, P. D., Mizukami, I., Smithson, G. M., Bradley, S. V., Parlow, A. F. & Ross, T. S., 2001, In : Molecular and Cellular Biology. 21, 22, p. 7796-7806 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

Regulation of the Src Homology 2-containing Inositol 5-Phosphatase SHIP1 in HIP1/PDGFβR-transformed Cells

Saint-Dic, D., Chang, S. C., Taylor, G. S., Provot, M. M. & Ross, T. S., Jun 15 2001, In : Journal of Biological Chemistry. 276, 24, p. 21192-21198 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
1999

Transforming properties of the huntingtin interacting protein 1/platelet-derived growth factor β receptor fusion protein

Ross, T. S. & Gilliland, D. G., Aug 6 1999, In : Journal of Biological Chemistry. 274, 32, p. 22328-22336 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
1998

Fusion of Huntingtin interacting protein 1 to platelet-derived growth factor βreceptor (PDGFβR) in chronic myelomonocytic leukemia with t(5;7)(q33;q11.2)

Ross, T. S., Bernard, O. A., Berger, R. & Gilliland, D. G., 1998, In : Blood. 91, 12, p. 4419-4426 8 p.

Research output: Contribution to journalArticle

160 Scopus citations

Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

Schwaller, J., Frantsve, J., Aster, J., Williams, I. R., Tomasson, M. H., Ross, T. S., Peeters, P., Van Rompaey, L., Van Etten, R. A., Ilaia, R., Marynen, P. & Gilliland, D. G., Sep 15 1998, In : EMBO Journal. 17, 18, p. 5321-5333 13 p.

Research output: Contribution to journalArticle

224 Scopus citations
1992

Identification of a phosphodiesterase that converts inositol cyclic 1: 2-Phosphate to inositol 2-phosphate

Ross, T. S. & Majerus, P. W., Oct 5 1992, In : Journal of Biological Chemistry. 267, 28, p. 19924-19928 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
8 Scopus citations
1991

Cloning and expression of human 75-kDa inositol polyphosphate- 5-phosphatase

Ross, T. S., Jefferson, A. B., Mitchell, C. A. & Majerus, P. W., 1991, In : Journal of Biological Chemistry. 266, 30, p. 20283-20289 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

Cyclic hydrolase-transfected 3T3 cells have low levels of inositol 1,2-cyclic phosphate and reach confluence at low density

Ross, T. S., Whiteley, B., Graham, R. A. & Majerus, P. W., 1991, In : Journal of Biological Chemistry. 266, 14, p. 9086-9092 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
5 Scopus citations

The phosphatidylinositol pathway of platelets and vascular cells

Majerus, P. W., Bansal, V. S., Lips, D. L., Ross, T. A., Mitchell, C. A., Caldwell, K. K. & Cunningham, T. W., 1991, In : Annals of the New York Academy of Sciences. 614, p. 44-50 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
1990

Identity of inositol 1,2-cyclic phosphate 2-phosphohydrolase with lipocortin III

Ross, T. S., Tait, J. F. & Majerus, P. W., May 4 1990, In : Science. 248, 4955, p. 605-607 3 p.

Research output: Contribution to journalArticle

69 Scopus citations