• 707 Citations
  • 9 h-Index
20062017
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Weirui Guo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 25 Similar Profiles
Metabotropic Glutamate 5 Receptor Medicine & Life Sciences
Fragile X Syndrome Medicine & Life Sciences
MEF2 Transcription Factors Medicine & Life Sciences
aspartyl-arginyl-valyl-tyrosyl-isoleucyl-histidyl-prolyl-phenylalanyl-histidyl-leucyl-valyl-isoleucyl-histidine Medicine & Life Sciences
Synapses Medicine & Life Sciences
DNA-Binding Proteins Medicine & Life Sciences
Autistic Disorder Medicine & Life Sciences
Knockout Mice Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2006 2017

  • 707 Citations
  • 9 h-Index
  • 9 Article
  • 1 Review article
10 Citations (Scopus)

FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination

Tsai, N. P., Wilkerson, J. R., Guo, W. & Huber, K. M., 2017, In : Human Molecular Genetics. 26, 2, p. 293-304 12 p.

Research output: Contribution to journalArticle

MEF2 Transcription Factors
Synapses
Neurons
Proteolysis
Peptide Elongation Factor 1
19 Citations (Scopus)

Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice

Ade, K. K., Wan, Y., Hamann, H. C., O'Hare, J. K., Guo, W., Quian, A., Kumar, S., Bhagat, S., Rodriguiz, R. M., Wetsel, W. C., Conn, P. J., Dzirasa, K., Huber, K. M. & Calakos, N., Oct 1 2016, In : Biological Psychiatry. 80, 7, p. 522-533 12 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate 5 Receptor
Corpus Striatum
Obsessive-Compulsive Disorder
Knockout Mice
Phenotype
17 Citations (Scopus)

Selective disruption of metabotropic glutamate receptor 5-homer interactions mimics phenotypes of fragile X syndrome in mice

Guo, W., Molinaro, G., Collins, K. A., Hays, S. A., Paylor, R., Worley, P. F., Szumlinski, K. K. & Huber, K. M., Feb 17 2016, In : Journal of Neuroscience. 36, 7, p. 2131-2147 17 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate 5 Receptor
Fragile X Syndrome
Knockout Mice
Phenotype
Sensory Gating
20 Citations (Scopus)

Elevated CaMKIIα and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model

Guo, W., Ceolin, L., Collins, K. A., Perroy, J. & Huber, K. M., May 14 2015, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

Metabotropic Glutamate 5 Receptor
Fragile X Syndrome
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Networks (circuits)
Scaffolds
142 Citations (Scopus)

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

Ronesi, J. A., Collins, K. A., Hays, S. A., Tsai, N. P., Guo, W., Birnbaum, S. G., Hu, J. H., Worley, P. F., Gibson, J. R. & Huber, K. M., Mar 2012, In : Nature Neuroscience. 15, 3, p. 431-440 10 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate 5 Receptor
Fragile X Syndrome
Autistic Disorder
Phenotype
Long-Term Synaptic Depression