• 1860 Citations
  • 16 h-Index
20032019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2003 2019

  • 1860 Citations
  • 16 h-Index
  • 27 Article
  • 3 Review article
  • 2 Comment/debate
  • 1 Chapter
Filter
Article
2019
15 Citations (Scopus)

Cerebellar ataxia disease-associated Snx14 promotes lipid droplet growth at ER-droplet contacts

Datta, S., Liu, Y., Hariri, H., Bowerman, J. & Henne, W. M., Apr 1 2019, In : The Journal of cell biology. 218, 4, p. 1335-1351 17 p.

Research output: Contribution to journalArticle

Open Access
Cerebellar Diseases
Cerebellar Ataxia
Endoplasmic Reticulum
Growth
Fatty Acids
8 Citations (Scopus)

Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities

Chandra, M., Chin, Y. K. Y., Mas, C., Feathers, J. R., Paul, B., Datta, S., Chen, K. E., Jia, X., Yang, Z., Norwood, S. J., Mohanty, B., Bugarcic, A., Teasdale, R. D., Henne, W. M., Mobli, M. & Collins, B. M., Dec 1 2019, In : Nature communications. 10, 1, 1528.

Research output: Contribution to journalArticle

Open Access
homology
Phosphatidylinositols
Phospholipids
lipids
Interferometry

Drosophila Snazarus Regulates a Lipid Droplet Population at Plasma Membrane-Droplet Contacts in Adipocytes

Ugrankar, R., Bowerman, J., Hariri, H., Chandra, M., Chen, K., Bossanyi, M. F., Datta, S., Rogers, S., Eckert, K. M., Dias do Vale, G., Victoria, A., Fresquez, J., McDonald, J. G., Jean, S., Collins, B. M. & Henne, W. M., Sep 9 2019, In : Developmental Cell. 50, 5, p. 557-572.e5

Research output: Contribution to journalArticle

Cell membranes
Adipocytes
Contacts (fluid mechanics)
Drosophila
Cell Membrane
13 Citations (Scopus)

Mdm1 maintains endoplasmic reticulum homeostasis by spatially regulating lipid droplet biogenesis

Hariri, H., Speer, N., Bowerman, J., Rogers, S., Fu, G., Reetz, E., Datta, S., Feathers, J. R., Ugrankar, R., Nicastro, D. & Henne, W. M., Apr 1 2019, In : The Journal of cell biology. 218, 4, p. 1319-1334 16 p.

Research output: Contribution to journalArticle

Open Access
Endoplasmic Reticulum
Homeostasis
Fatty Acids
Vacuoles
Yeasts
2018
1 Citation (Scopus)

Circulating glucose levels inversely correlate with Drosophila larval feeding through insulin signaling and SLC5A11

Ugrankar, R., Theodoropoulos, P., Akdemir, F., Henne, W. M. & Graff, J. M., Dec 1 2018, In : Communications Biology. 1, 1, 110.

Research output: Contribution to journalArticle

Open Access
Drosophila
insulin
Insulin
Glucose
glucose
27 Citations (Scopus)

Lipid droplet biogenesis is spatially coordinated at ER–vacuole contacts under nutritional stress

Hariri, H., Rogers, S., Ugrankar, R., Liu, Y. L., Feathers, J. R. & Henne, W. M., Jan 1 2018, In : EMBO Reports. 19, 1, p. 57-72 16 p.

Research output: Contribution to journalArticle

Contacts (fluid mechanics)
Lipids
Acyl Coenzyme A
Physiological Stress
Eukaryotic Cells
1 Citation (Scopus)

Organelles in metabolism and stress responses

Ferguson, S. M. & Henne, W. M., Mar 15 2018, In : Molecular Biology of the Cell. 29, 6, 1 p.

Research output: Contribution to journalArticle

Organelles
12 Citations (Scopus)

SNX14 mutations affect endoplasmic reticulumassociated neutral lipid metabolism in autosomal recessive spinocerebellar ataxia 20

Bryant, D., Liu, Y., Datta, S., Hariri, H., Seda, M., Anderson, G., Peskett, E., Demetriou, C., Sousa, S., Jenkins, D., Clayton, P., Bitner-Glindzicz, M., Moore, G. E., Henne, W. M. & Stanier, P., Jun 1 2018, In : Human Molecular Genetics. 27, 11, p. 1927-1940 14 p.

Research output: Contribution to journalArticle

Lipid Metabolism
Endoplasmic Reticulum
Mutation
Lysosomes
Cerebellar Ataxia
2016
5 Citations (Scopus)

Organelle remodeling at membrane contact sites

Henne, W. M., Oct 1 2016, In : Journal of Structural Biology. 196, 1, p. 15-19 5 p.

Research output: Contribution to journalArticle

Organelles
Membranes
Organelle Shape
Biological Phenomena
Sterols
2015
45 Citations (Scopus)

Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein

Henne, W. M., Zhu, L., Balogi, Z., Stefan, C., Pleiss, J. A. & Emr, S. D., Aug 17 2015, In : The Journal of cell biology. 210, 4, p. 541-551 11 p.

Research output: Contribution to journalArticle

Vacuoles
Endoplasmic Reticulum
Proteins
Sphingolipids
Membranes
62 Citations (Scopus)

Molecular mechanisms of inter-organelle ER-PM contact sites

Henne, W. M., Liou, J. & Emr, S. D., Aug 1 2015, In : Current Opinion in Cell Biology. 35, p. 123-130 8 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum
Organelles
Cell Membrane
Membranes
Lipids
38 Citations (Scopus)

Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments

Tang, S., Henne, W. M., Borbat, P. P., Buchkovich, N. J., Freed, J. H., Mao, Y., Fromme, J. C. & Emr, S. D., Dec 15 2015, In : eLife. 4, DECEMBER2015, e12548.

Research output: Contribution to journalArticle

Endosomal Sorting Complexes Required for Transport
Chemical activation
Membranes
Electron spin resonance spectroscopy
Proteins
2013
46 Citations (Scopus)

Essential N-Terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation

Buchkovich, N. J., Henne, W. M., Tang, S. & Emr, S. D., Oct 28 2013, In : Developmental Cell. 27, 2, p. 201-214 14 p.

Research output: Contribution to journalArticle

Endosomal Sorting Complexes Required for Transport
Anchors
Membranes
Polymers
Static Electricity
46 Citations (Scopus)

Molecular mechanisms of the membrane sculpting ESCRT pathway

Henne, W. M., Stenmark, H. & Emr, S. D., 2013, In : Cold Spring Harbor perspectives in medicine. 3, 10, a016766.

Research output: Contribution to journalArticle

Endosomal Sorting Complexes Required for Transport
Membranes
Multivesicular Bodies
Morphogenesis
Cytology
131 Citations (Scopus)

Molecular mechanisms of the membrane sculpting ESCRT pathway

Henne, W. M., Stenmark, H. & Emr, S. D., 2013, In : Cold Spring Harbor perspectives in medicine. 3, 9

Research output: Contribution to journalArticle

Endosomal Sorting Complexes Required for Transport
Membranes
Multivesicular Bodies
Morphogenesis
Cytology
2012
38 Citations (Scopus)

PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts

Chitu, V., Nacu, V., Charles, J. F., Henne, W. M., McMahon, H. T., Nandi, S., Ketchum, H., Harris, R., Nakamura, M. C. & Stanley, E. R., Oct 11 2012, In : Blood. 120, 15, p. 3126-3135 10 p.

Research output: Contribution to journalArticle

Protein Deficiency
Metabolic Bone Diseases
Phosphoprotein Phosphatases
Osteoclasts
Proline
105 Citations (Scopus)

The endosomal sorting complex ESCRT-II mediates the assembly and architecture of ESCRT-III helices

Henne, W. M., Buchkovich, N. J., Zhao, Y. & Emr, S. D., Oct 12 2012, In : Cell. 151, 2, p. 356-371 16 p.

Research output: Contribution to journalArticle

Endosomal Sorting Complexes Required for Transport
Sorting
Membranes
Multivesicular Bodies
Cytokinesis
2011
31 Citations (Scopus)

Intracellular curvature-generating proteins in cell-to-cell fusion

Richard, J. P., Leikina, E., Langen, R., Henne, W. M., Popova, M., Balla, T., Mcmahon, H. T., Kozlov, M. M. & Chernomordik, L. V., Dec 1 2011, In : Biochemical Journal. 440, 2, p. 185-193 9 p.

Research output: Contribution to journalArticle

Cell Fusion
Dynamins
Fusion reactions
Intracellular Membranes
Giant Cells
622 Citations (Scopus)

The ESCRT Pathway

Henne, W. M., Buchkovich, N. J. & Emr, S. D., Jul 19 2011, In : Developmental Cell. 21, 1, p. 77-91 15 p.

Research output: Contribution to journalArticle

Endosomal Sorting Complexes Required for Transport
Multivesicular Bodies
Membranes
Vacuoles
Lysosomes
2010
48 Citations (Scopus)

Dissecting BAR domain function in the yeast amphiphysins Rvs161 and Rvs167 during endocytosis

Youn, J. Y., Friesen, H., Kishimoto, T., Henne, W. M., Kurat, C. F., Ye, W., Ceccarelli, D. F., Sicheri, F., Kohlwein, S. D., McMahon, H. T. & Andrews, B. J., Sep 1 2010, In : Molecular Biology of the Cell. 21, 17, p. 3054-3069 16 p.

Research output: Contribution to journalArticle

Endocytosis
Yeasts
Membranes
Sphingolipids
Saccharomycetales
244 Citations (Scopus)

FCHo proteins are nucleators of Clathrin-Mediated endocytosis

Henne, W. M., Boucrot, E., Meinecke, M., Evergren, E., Vallis, Y., Mittal, R. & McMahon, H. T., Jun 4 2010, In : Science. 328, 5983, p. 1281-1284 4 p.

Research output: Contribution to journalArticle

Clathrin-Coated Vesicles
Clathrin
Endocytosis
Proteins
Vesicular Transport Adaptor Proteins
2008
1 Citation (Scopus)

AMPA-induced dark cell degeneration is associated with activation of caspases in pyramidal neurons of the rat hippocampus

Coles, J., Oomman, S. K., Henne, W. M., Bliss, R. M., Hoffman, T. C., Finckbone, V., Strahlendorf, H. & Strahlendorf, J., May 16 2008, In : Neuroscience Letters. 436, 3, p. 294-299 6 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Pyramidal Cells
Caspases
Caspase 9
Hippocampus
2007
13 Citations (Scopus)

Involvement of calpain in AMPA-induced toxicity to rat cerebellar Purkinje neurons

Mansouri, B., Henne, W. M., Oomman, S. K., Bliss, R., Attridge, J., Finckbone, V., Zeitouni, T., Hoffman, T., Bahr, B. A., Strahlendorf, H. K. & Strahlendorf, J. C., Feb 28 2007, In : European Journal of Pharmacology. 557, 2-3, p. 106-114 9 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Calpain
Purkinje Cells
AMPA Receptors
Cell Death
192 Citations (Scopus)

Structure and Analysis of FCHo2 F-BAR Domain: A Dimerizing and Membrane Recruitment Module that Effects Membrane Curvature

Henne, W. M., Kent, H. M., Ford, M. G. J., Hegde, B. G., Daumke, O., Butler, P. J. G., Mittal, R., Langen, R., Evans, P. R. & McMahon, H. T., Jul 18 2007, In : Structure. 15, 7, p. 839-852 14 p.

Research output: Contribution to journalArticle

Membranes
Phenylalanine
Liposomes
Mutation
Proteins
2006
6 Citations (Scopus)

AMPA-induced excitotoxicity increases nuclear levels of CAD, Endonuclease G, and acinus and induces chromatin condensation in rat hippocampal pyramidal neurons

Henne, W. M., Oomman, S., Attridge, J., Finckbone, V., Coates, P., Bliss, R., Strahlendorf, H. & Strahlendorf, J., May 2006, In : Cellular and Molecular Neurobiology. 26, 3, p. 321-341 21 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Pyramidal Cells
Neurons
Chromatin
Rats
2004
48 Citations (Scopus)

Active caspase-3 expression during postnatal development of rat cerebellum is not systematically or consistently associated with apoptosis

Oomman, S., Finckbone, V., Dertien, J., Attridge, J., Henne, W., Medina, M., Mansouri, B., Singh, H., Strahlendorf, H. & Strahlendorf, J., Aug 16 2004, In : Journal of Comparative Neurology. 476, 2, p. 154-173 20 p.

Research output: Contribution to journalArticle

Caspase 3
Cerebellum
Apoptosis
Cell Differentiation
Cell Proliferation
2003
15 Citations (Scopus)

AMPA-induced dark cell degeneration of cerebellar Purkinje neurons involves activation of caspases and apparent mitochondrial dysfunction

Strahlendorf, J., Box, C., Attridge, J., Diertien, J., Finckbone, V., Henne, W. M., Medina, M. S., Miles, R., Oomman, S., Schneider, M., Singh, H., Veliyaparabil, M. & Strahlendorf, H., Dec 24 2003, In : Brain Research. 994, 2, p. 146-159 14 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Purkinje Cells
Caspases
Mitochondria
Caspase 9