• 4197 Citations
  • 35 h-Index
19992020

Research output per year

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Research Output

  • 4197 Citations
  • 35 h-Index
  • 93 Article
  • 7 Conference contribution
  • 3 Review article
  • 2 Chapter
2020

Gliomas Interact with Non-glioma Brain Cells via Extracellular Vesicles

Gao, X., Zhang, Z., Mashimo, T., Shen, B., Nyagilo, J., Wang, H., Wang, Y., Liu, Z., Mulgaonkar, A., Hu, X. L., Piccirillo, S. G. M., Eskiocak, U., Davé, D. P., Qin, S., Yang, Y., Sun, X., Fu, Y. X., Zong, H., Sun, W., Bachoo, R. M. & 1 others, Ge, W. P., Feb 25 2020, In : Cell Reports. 30, 8, p. 2489-2500.e5

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Injectable Click Chemistry-based Bioadhesives for Accelerated Wound Closure

Li, S., Zhou, J., Huang, Y. H., Roy, J., Zhou, N., Yum, K., Sun, X. & Tang, L., Jan 1 2020, (Accepted/In press) In : Acta Biomaterialia.

Research output: Contribution to journalArticle

PET imaging of occult tumours by temporal integration of tumour-acidosis signals from pH-sensitive 64Cu-labelled polymers

Huang, G., Zhao, T., Wang, C., Nham, K., Xiong, Y., Gao, X., Wang, Y., Hao, G., Ge, W. P., Sun, X., Sumer, B. D. & Gao, J., Mar 1 2020, In : Nature Biomedical Engineering. 4, 3, p. 314-324 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019
Open Access
8 Scopus citations

Tumor uptake of triazine dendrimers decorated with four, sixteen, and sixty-four PSMA-targeted ligands: Passive versus active tumor targeting

Lim, J., Guan, B., Nham, K., Hao, G., Sun, X. & Simanek, E. E., Sep 1 2019, In : Biomolecules. 9, 9, 421.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents

Zhang, F., Hao, G., Shao, M., Nham, K., An, Y., Wang, Q., Zhu, Y., Kusminski, C., Hassan, G., Gupta, R. K., Zhai, Q., Sun, X., Scherer, P. E. & Oz, O. K., Jan 9 2018, In : Cell Metabolism. 27, 1, p. 252-262.e3

Research output: Contribution to journalArticle

30 Scopus citations

Bombesin functionalized 64 Cu-copper sulfide nanoparticles for targeted imaging of orthotopic prostate cancer

Cai, H., Xie, F., Mulgaonkar, A., Chen, L., Sun, X., Hsieh, J. T., Peng, F., Tian, R., Li, L., Wu, C. & Ai, H., Jan 1 2018, In : Nanomedicine. 13, 14

Research output: Contribution to journalArticle

6 Scopus citations

PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

Tang, H., Liang, Y., Anders, R. A., Taube, J. M., Qiu, X., Mulgaonkar, A., Liu, X., Harrington, S. M., Guo, J., Xin, Y., Xiong, Y., Nham, K., Silvers, W., Hao, G., Sun, X., Chen, M., Hannan, R., Qiao, J., Dong, H., Peng, H. & 1 others, Fu, Y. X., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 580-588 9 p.

Research output: Contribution to journalArticle

100 Scopus citations
2017

A transistor-like pH nanoprobe for tumour detection and image-guided surgery

Zhao, T., Huang, G., Li, Y., Yang, S., Ramezani, S., Lin, Z., Wang, Y., Ma, X., Zeng, Z., Luo, M., De Boer, E., Xie, X. J., Thibodeaux, J., Brekken, R. A., Sun, X., Sumer, B. D. & Gao, J., Jan 10 2017, In : Nature Biomedical Engineering. 1, 1, 0006.

Research output: Contribution to journalArticle

58 Scopus citations

Control of cerebral ischemia with magnetic nanoparticles

Jia, J. M., Chowdary, P. D., Gao, X., Ci, B., Li, W., Mulgaonkar, A., Plautz, E. J., Hassan, G., Kumar, A., Stowe, A. M., Yang, S. H., Zhou, W., Sun, X., Cui, B. & Ge, W. P., Feb 1 2017, In : Nature Methods. 14, 2, p. 160-166 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Feasibility study of direct beta particle detection using gas electron multiplier

Izudike, B., Yu, J., Chen, W., Sun, X., Balch, G. C. & Jin, M., Oct 16 2017, 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop, NSS/MIC/RTSD 2016. Institute of Electrical and Electronics Engineers Inc., 8069521. (2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop, NSS/MIC/RTSD 2016; vol. 2017-January).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hollow gold nanoparticles as efficient in vivo radiosensitizing agents for radiation therapy of breast cancer

Mulgaonkar, A., Moeendarbari, S., Silvers, W., Hassan, G., Sun, X., Hao, Y. & Mao, W., May 1 2017, In : Journal of Biomedical Nanotechnology. 13, 5, p. 566-574 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Interactions of Renal-Clearable Gold Nanoparticles with Tumor Microenvironments: Vasculature and Acidity Effects

Yu, M., Zhou, C., Liu, L., Zhang, S., Sun, S., Hankins, J. D., Sun, X. & Zheng, J., Apr 3 2017, In : Angewandte Chemie - International Edition. 56, 15, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

The Warburg effect and glucose-derived cancer theranostics

Tekade, R. K. & Sun, X., 2017, (Accepted/In press) In : Drug Discovery Today.

Research output: Contribution to journalArticle

38 Scopus citations
2016
5 Scopus citations

Design of a Small-Molecule Drug Conjugate for Prostate Cancer Targeted Theranostics

Kumar, A., Mastren, T., Wang, B., Hsieh, J. T., Hao, G. & Sun, X., Jul 20 2016, In : Bioconjugate Chemistry. 27, 7, p. 1681-1689 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Spatial and temporal processing for functional imaging probes

Jin, M., Zhao, C., Yu, J., Chen, W., Hao, G., Sun, X. & Balch, G., Mar 10 2016, 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014. Institute of Electrical and Electronics Engineers Inc., 7430819

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Spatial denoising methods for low count functional images

Jin, M., Yu, J., Chen, W., Hao, G., Sun, X. & Balch, G., Oct 3 2016, 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015. Institute of Electrical and Electronics Engineers Inc., 7582233

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Targeting renal cell carcinoma with a HIF-2 antagonist

Chen, W., Hill, H., Christie, A., Kim, M. S., Holloman, E., Pavia-Jimenez, A., Homayoun, F., Ma, Y., Patel, N., Yell, P., Hao, G., Yousuf, Q., Joyce, A., Pedrosa, I., Geiger, H., Zhang, H., Chang, J., Gardner, K. H., Bruick, R. K., Reeves, C. & 14 others, Hwang, T. H., Courtney, K., Frenkel, E., Sun, X., Zojwalla, N., Wong, T., Rizzi, J. P., Wallace, E. M., Josey, J. A., Xie, Y., Xie, X. J., Kapur, P., McKay, R. M. & Brugarolas, J., 2016, In : Nature. 539, 7627, p. 112-117 6 p.

Research output: Contribution to journalArticle

205 Scopus citations

Theranostic Nanoseeds for Efficacious Internal Radiation Therapy of Unresectable Solid Tumors

Moeendarbari, S., Tekade, R., Mulgaonkar, A., Christensen, P., Ramezani, S., Hassan, G., Jiang, R., Öz, O. K., Hao, Y. & Sun, X., Feb 8 2016, In : Scientific Reports. 6, 20614.

Research output: Contribution to journalArticle

31 Scopus citations
2015

[68Ga]-HP-DO3A-nitroimidazole: A promising agent for PET detection of tumor hypoxia

Wu, Y., Hao, G., Ramezani, S., Saha, D., Zhao, D., Sun, X. & Sherry, A. D., Nov 1 2015, In : Contrast Media and Molecular Imaging. 10, 6, p. 465-472 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

A comparative study of trans- and cis-isomers of a bone-seeking agent, DO2A2P

Hao, G., Liu, W., Hassan, G., Öz, O. K., Kovacs, Z. & Sun, X., Feb 1 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 3, p. 571-574 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Click-chemistry strategy for labeling antibodies with copper-64 via a cross-bridged tetraazamacrocyclic chelator scaffold

Kumar, A., Hao, G., Liu, L., Ramezani, S., Hsieh, J. T., Öz, O. K. & Sun, X., Apr 15 2015, In : Bioconjugate Chemistry. 26, 4, p. 782-789 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Comparative evaluation of two venous sampling techniques for the assessment of pancreatic insulin and zinc release upon glucose challenge

Pillai, A. K., Silvers, W., Christensen, P., Riegel, M., Adams-Huet, B., Lingvay, I., Sun, X. & Öz, O. K., 2015, In : Journal of Diabetes Research. 2015, 789359.

Research output: Contribution to journalArticle

C-terminal variable AGES domain of Thymosin β4: The molecule's primary contribution in support of post-ischemic cardiac function and repair

Hinkel, R., Ball, H. L., DiMaio, J. M., Shrivastava, S., Thatcher, J. E., Singh, A. N., Sun, X., Faskerti, G., Olson, E. N., Kupatt, C. & Bock-Marquette, I., Oct 1 2015, In : Journal of Molecular and Cellular Cardiology. 87, p. 113-125 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Delivery and controlled release of therapeutics via dendrimer scaffolds

Lo, S. T., Kumar, A. & Sun, X., Jul 1 2015, Nanoparticles for Biotherapeutic Delivery. Future Medicine Ltd., Vol. 2. p. 15-30 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis

Pozo, K., Hillmann, A., Augustyn, A., Plattner, F., Hai, T., Singh, T., Ramezani, S., Sun, X., Pfragner, R., Minna, J. D., Cote, G. J., Chen, H., Bibb, J. A. & Nwariaku, F. E., Jan 1 2015, In : Oncotarget. 6, 14, p. 12080-12093 14 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Hollow gold nanoparticles as biocompatible radiosensitizer: An in vitro proof of concept study

Huang, C., Kearney, V., Moeendarbari, S., Jiang, R., Christensen, P., Tekade, R., Sun, X., Mao, W. & Hao, Y., 2015, In : Journal of Nano Research. 32, p. 106-112 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Molecular Platform for Design and Synthesis of Targeted Dual-Modality Imaging Probes

Kumar, A., Zhang, S., Hao, G., Hassan, G., Ramezani, S., Sagiyama, K., Lo, S. T., Takahashi, M., Sherry, A. D., Öz, O. K., Kovacs, Z. & Sun, X., Mar 18 2015, In : Bioconjugate Chemistry. 26, 3, p. 549-558 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Renal Clearance and Degradation of Glutathione-Coated Copper Nanoparticles

Yang, S., Sun, S., Zhou, C., Hao, G., Liu, J., Ramezani, S., Yu, M., Sun, X. & Zheng, J., Mar 18 2015, In : Bioconjugate Chemistry. 26, 3, p. 511-519 9 p.

Research output: Contribution to journalArticle

42 Scopus citations
4 Scopus citations
2014
4 Scopus citations

Dimerization of a phage-display selected peptide for imaging of αvβ6- integrin: Two approaches to the multivalent effect

Singh, A. N., McGuire, M. J., Li, S., Hao, G., Kumar, A., Sun, X. & Brown, K. C., Jan 1 2014, In : Theranostics. 4, 7, p. 745-760 16 p.

Research output: Contribution to journalArticle

18 Scopus citations

Enantiopure bifunctional chelators for copper radiopharmaceuticals - Does chirality matter in radiotracer design?

Singh, A. N., Dakanali, M., Hao, G., Ramezani, S., Kumar, A. & Sun, X., Jun 10 2014, In : European Journal of Medicinal Chemistry. 80, p. 308-315 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Glutathione-coated luminescent gold nanoparticles: A surface ligand for minimizing serum protein adsorption

Vinluan, R. D., Liu, J., Zhou, C., Yu, M., Yang, S., Kumar, A., Sun, S., Dean, A., Sun, X. & Zheng, J., Aug 13 2014, In : ACS Applied Materials and Interfaces. 6, 15, p. 11829-11833 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models

Nguyen, L. H., Robinton, D. A., Seligson, M. T., Wu, L., Li, L., Rakheja, D., Comerford, S. A., Ramezani, S., Sun, X., Parikh, M. S., Yang, E. H., Powers, J. T., Shinoda, G., Shah, S. P., Hammer, R. E., Daley, G. Q. & Zhu, H., Aug 11 2014, In : Cancer Cell. 26, 2, p. 248-261 14 p.

Research output: Contribution to journalArticle

96 Scopus citations

The role of DAB2IP in androgen receptor activation during prostate cancer progression

Wu, K., Liu, J., Tseng, S. F., Gore, C., Ning, Z., Sharifi, N., Fazli, L., Gleave, M., Kapur, P., Xiao, G., Sun, X., Oz, O. K., Min, W., Alexandrakis, G., Yang, C. R., Hsieh, C. L., Wu, H. C., He, D., Xie, D. & Hsieh, J. T., Apr 10 2014, In : Oncogene. 33, 15, p. 1954-1963 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Use of Fc-engineered antibodies as clearing agents to increase contrast during PET

Swiercz, R., Chiguru, S., Tahmasbi, A., Ramezani, S. M., Hao, G., Challa, D. K., Lewis, M. A., Kulkarni, P. V., Sun, X., Ober, R. J., Mason, R. P. & Ward, E. S., Jul 1 2014, In : Journal of Nuclear Medicine. 55, 7, p. 1204-1207 4 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Acceleration of the acquisition of imaging probes using spatiotemporal processing

Jin, M., Zhao, C., Yu, J., Chen, W., Hao, G. & Sun, X., Jan 1 2013, 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013. Institute of Electrical and Electronics Engineers Inc., 6829274. (IEEE Nuclear Science Symposium Conference Record).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations
6 Scopus citations

Dendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry

Lo, S. T., Kumar, A., Hsieh, J. T. & Sun, X., Mar 11 2013, In : Molecular Pharmaceutics. 10, 3, p. 793-812 20 p.

Research output: Contribution to journalReview article

66 Scopus citations

Dendrimers terminated with dichlorotriazine groups provide a route to compositional diversity

Patra, S., Kozura, B., Huang, A. Y. T., Enciso, A. E., Sun, X., Hsieh, J. T., Kao, C. L., Chen, H. T. & Simanek, E. E., Aug 2 2013, In : Organic Letters. 15, 15, p. 3808-3811 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Design, synthesis and biological assessment of a triazine dendrimer with approximately 16 paclitaxel groups and 8 PEG groups

Lee, C., Lo, S. T., Lim, J., Da Costa, V. C. P., Ramezani, S., Öz, O. K., Pavan, G. M., Annunziata, O., Sun, X. & Simanek, E. E., Dec 2 2013, In : Molecular Pharmaceutics. 10, 12, p. 4452-4461 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Highly specific PET imaging of prostate tumors in mice with an iodine-124-labeled antibody fragment that targets phosphatidylserine

Stafford, J. H., Hao, G., Best, A. M., Sun, X. & Thorpe, P. E., Dec 19 2013, In : PloS one. 8, 12, e84864.

Research output: Contribution to journalArticle

14 Scopus citations

In vivo evaluation of medical device-associated inflammation using a macrophage-specific positron emission tomography (PET) imaging probe

Zhou, J., Hao, G., Weng, H., Tsai, Y. T., Baker, D. W., Sun, X. & Tang, L., Apr 1 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 7, p. 2044-2047 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Serial Non-Invasive Assessment of Antibody Induced Nephritis in Mice Using Positron Emission Tomography

Hao, G., Du, Y., Zhou, X. J., Guo, J., Sun, X., Mohan, C. & Öz, O. K., Feb 27 2013, In : PloS one. 8, 2, e57418.

Research output: Contribution to journalArticle

6 Scopus citations

The effect of erythropoietin on autologous stem cell-mediated bone regeneration

Nair, A. M., Tsai, Y. T., Shah, K. M., Shen, J., Weng, H., Zhou, J., Sun, X., Saxena, R., Borrelli, J. & Tang, L., Oct 1 2013, In : Biomaterials. 34, 30, p. 7364-7371 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

The Role of Cdk5 in Neuroendocrine Thyroid Cancer

Pozo, K., Castro-Rivera, E., Tan, C., Plattner, F., Schwach, G., Siegl, V., Meyer, D., Guo, A., Gundara, J., Mettlach, G., Richer, E., Guevara, J. A., Ning, L., Gupta, A., Hao, G., Tsai, L. H., Sun, X., Antich, P., Sidhu, S., Robinson, B. G. & 5 others, Chen, H., Nwariaku, F. E., Pfragner, R., Richardson, J. A. & Bibb, J. A., Oct 14 2013, In : Cancer Cell. 24, 4, p. 499-511 13 p.

Research output: Contribution to journalArticle

81 Scopus citations

WE‐E‐108‐01: BEST IN PHYSICS (THERAPY) ‐ Radiotherapy Enhancement with a Novel Class of Hollow Nanoconstructs

Mao, W., Huang, C., Kearney, V., Song, K., Christensen, P., Sun, X., Hao, Y. & Solberg, T., 2013, In : Medical Physics. 40, 6, p. 488 1 p.

Research output: Contribution to journalArticle

2012

Analysis of oligo-arginine cell-permeable peptides uptake by prostate cells

Zhou, J., Liu, W., Pong, R. C., Hao, G., Sun, X. & Hsieh, J. T., Apr 1 2012, In : Amino Acids. 42, 4, p. 1253-1260 8 p.

Research output: Contribution to journalArticle

16 Scopus citations