• 4197 Citations
  • 35 h-Index
19992020

Research output per year

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Research Output

  • 4197 Citations
  • 35 h-Index
  • 93 Article
  • 7 Conference contribution
  • 3 Review article
  • 2 Chapter
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Article

MicroPET imaging of MCF-7 tumors in mice via unr mRNA-targeted peptide nucleic acids

Sun, X., Fang, H., Li, X., Rossin, R., Welch, M. J. & Taylor, J. S., Mar 1 2005, In : Bioconjugate Chemistry. 16, 2, p. 294-305 12 p.

Research output: Contribution to journalArticle

48 Scopus citations

Molecular Platform for Design and Synthesis of Targeted Dual-Modality Imaging Probes

Kumar, A., Zhang, S., Hao, G., Hassan, G., Ramezani, S., Sagiyama, K., Lo, S. T., Takahashi, M., Sherry, A. D., Öz, O. K., Kovacs, Z. & Sun, X., Mar 18 2015, In : Bioconjugate Chemistry. 26, 3, p. 549-558 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting

De León-Rodríguez, L. M., Lubag, A., Udugamasooriya, D. G., Proneth, B., Brekken, R. A., Sun, X., Kodadek, T. & Dean Sherry, A., Sep 22 2010, In : Journal of the American Chemical Society. 132, 37, p. 12829-12831 3 p.

Research output: Contribution to journalArticle

34 Scopus citations

Multivalent bifunctional chelator scaffolds for gallium-68 based positron emission tomography imaging probe design: Signal amplification via multivalency

Singh, A. N., Liu, W., Hao, G., Kumar, A., Gupta, A., Öz, O. K., Hsieh, J. T. & Sun, X., Aug 17 2011, In : Bioconjugate Chemistry. 22, 8, p. 1650-1662 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Near-infrared emitting radioactive gold nanoparticles with molecular pharmacokinetics

Zhou, C., Hao, G., Thomas, P., Liu, J., Yu, M., Sun, S., Öz, O. K., Sun, X. & Zheng, J., Oct 1 2012, In : Angewandte Chemie - International Edition. 51, 40, p. 10118-10122 5 p.

Research output: Contribution to journalArticle

104 Scopus citations

Novel synthetic ligands for targeted PET imaging and radiotherapy of copper

Chong, H. S., Mhaske, S., Lin, M., Bhuniya, S., Song, H. A., Brechbiel, M. W. & Sun, X., Nov 15 2007, In : Bioorganic and Medicinal Chemistry Letters. 17, 22, p. 6107-6110 4 p.

Research output: Contribution to journalArticle

25 Scopus citations
Open Access
8 Scopus citations

PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

Tang, H., Liang, Y., Anders, R. A., Taube, J. M., Qiu, X., Mulgaonkar, A., Liu, X., Harrington, S. M., Guo, J., Xin, Y., Xiong, Y., Nham, K., Silvers, W., Hao, G., Sun, X., Chen, M., Hannan, R., Qiao, J., Dong, H., Peng, H. & 1 others, Fu, Y. X., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 580-588 9 p.

Research output: Contribution to journalArticle

100 Scopus citations

PET imaging of occult tumours by temporal integration of tumour-acidosis signals from pH-sensitive 64Cu-labelled polymers

Huang, G., Zhao, T., Wang, C., Nham, K., Xiong, Y., Gao, X., Wang, Y., Hao, G., Ge, W. P., Sun, X., Sumer, B. D. & Gao, J., Mar 1 2020, In : Nature Biomedical Engineering. 4, 3, p. 314-324 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

PET with non-standard nuclides

Hao, G., Singh, A. N., Liu, W. & Sun, X., Aug 20 2010, In : Current topics in medicinal chemistry. 10, 11, p. 1096-1112 17 p.

Research output: Contribution to journalArticle

13 Scopus citations

Porous Hollow gold nanoparticles for cancer SERS imaging

Huang, C., Hao, Y., Nyagilo, J., Dave, D. P., Xu, L. & Sun, X., Apr 7 2010, In : Journal of Nano Research. 10, p. 137-148 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Positron emission tomography of copper metabolism in the Atp7b -/- knock-out mouse model of Wilson's disease

Peng, F., Lutsenko, S., Sun, I. & Muzik, O., Feb 1 2012, In : Molecular Imaging and Biology. 14, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Preparation and biological evaluation of copper-64-labeled Tyr 3-octreotate using a cross-bridged macrocyclic chelator

Sprague, J. E., Peng, Y., Sun, X., Weisman, G. R., Wong, E. H., Achilefu, S. & Anderson, C. J., Dec 15 2004, In : Clinical Cancer Research. 10, 24, p. 8674-8682 9 p.

Research output: Contribution to journalArticle

139 Scopus citations

Preparation and evaluation of a radioisotope-incorporated iron oxide core/Au shell nanoplatform for dual modality imaging

Zhou, Y. F., Gulaka, P., Zhou, J., Xiao, M., Xu, D., Hsieh, J. T., Kodibagkar, V. D. & Sun, X., Dec 1 2008, In : Journal of biomedical nanotechnology. 4, 4, p. 474-481 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Production and applications of copper-64 radiopharmaceuticals

Sun, X. & Anderson, C. J., Jan 1 2004, In : Methods in Enzymology. 386, p. 237-261 25 p.

Research output: Contribution to journalArticle

47 Scopus citations

Radiochemical synthesis, rodent biodistribution and tumor uptake, and dosimetry calculations of [11C] methylated LY2181308

Dence, C. S., Laforest, R., Sun, X., Sharp, T. L., Welch, M. J. & MacH, R. H., Dec 1 2010, In : Molecular Imaging and Biology. 12, 6, p. 608-615 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Radiolabeling and in vivo behavior of copper-64-labeled cross-bridged cyclam ligands

Sun, X., Wuest, M., Weisman, G. R., Wong, E. H., Reed, D. P., Boswell, C. A., Motekaitis, R., Martell, A. E., Welch, M. J. & Anderson, C. J., Jan 17 2002, In : Journal of Medicinal Chemistry. 45, 2, p. 469-477 9 p.

Research output: Contribution to journalArticle

193 Scopus citations

Rational design and assembly of M2M′3L6 supramolecular clusters with C3h symmetry by exploiting incommensurate symmetry numbers

Sun, X., Johnson, D. W., Caulder, D. L., Raymond, K. N. & Wong, E. H., Oct 10 2001, In : Journal of the American Chemical Society. 123, 12, p. 2752-2763 12 p.

Research output: Contribution to journalArticle

101 Scopus citations

Renal Clearance and Degradation of Glutathione-Coated Copper Nanoparticles

Yang, S., Sun, S., Zhou, C., Hao, G., Liu, J., Ramezani, S., Yu, M., Sun, X. & Zheng, J., Mar 18 2015, In : Bioconjugate Chemistry. 26, 3, p. 511-519 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Retention of the radiotracers 64Cu-ATSM and 64Cu-PTSM in human and murine tumors is influenced by MDR1 protein expression

Liu, J., Hajibeigi, A., Ren, G., Lin, M., Siyambalapitiyage, W., Liu, Z., Simpson, E., Parkey, R. W., Sun, X. & Öz, O. K., Aug 1 2009, In : Journal of Nuclear Medicine. 50, 8, p. 1332-1339 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Xie, D., Gore, C., Liu, J., Pong, R. C., Mason, R., Hao, G., Long, M., Kabbani, W., Yu, L., Zhang, H., Chen, H., Sun, X., Boothman, D. A., Min, W. & Hsieh, J. T., Feb 9 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 6, p. 2485-2490 6 p.

Research output: Contribution to journalArticle

167 Scopus citations

Serial Non-Invasive Assessment of Antibody Induced Nephritis in Mice Using Positron Emission Tomography

Hao, G., Du, Y., Zhou, X. J., Guo, J., Sun, X., Mohan, C. & Öz, O. K., Feb 27 2013, In : PloS one. 8, 2, e57418.

Research output: Contribution to journalArticle

6 Scopus citations

Synthesis, potentiometric, kinetic, and NMR studies of 1,4,7,10- tetraazacyclododecane-1,7-bis(acetic acid)-4,10-bis(methylenephosphonic acid) (DO2A2P) and its complexes with Ca(II), Cu(II), Zn(II) and lanthanide(III) ions

Kálmán, F. K., Baranyai, Z., Tóth, I., Bányai, I., Király, R., Brücher, E., Aime, S., Sun, X., Sherry, A. D. & Kovács, Z., May 5 2008, In : Inorganic Chemistry. 47, 9, p. 3851-3862 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

Synthesis and characterization of a high-affinity α vβ 6-specific ligand for in vitro and in vivo applications

Li, S., McGuire, M. J., Lin, M., Liu, Y. H., Oyama, T., Sun, X. & Brown, K. C., May 1 2009, In : Molecular Cancer Therapeutics. 8, 5, p. 1239-1249 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
4 Scopus citations

Synthesis and evaluation of lanthanide ion DOTA-tetraamide complexes bearing peripheral hydroxyl groups

Pasha, A., Lin, M., Tircsó, G., Rostollan, C. L., Woods, M., Kiefer, G. E., Sherry, A. D. & Sun, X., Mar 1 2009, In : Journal of Biological Inorganic Chemistry. 14, 3, p. 421-438 18 p.

Research output: Contribution to journalArticle

14 Scopus citations

Synthesis and PET imaging studies of [18F]2-fluoroquinolin-8-ol ([18F]CABS13) in transgenic mouse models of Alzheimer's disease

Vasdev, N., Cao, P., Van Oosten, E. M., Wilson, A. A., Houle, S., Hao, G., Sun, X., Slavine, N., Alhasan, M., Antich, P. P., Bonte, F. J. & Kulkarni, P., Oct 2012, In : MedChemComm. 3, 10, p. 1228-1230 3 p.

Research output: Contribution to journalArticle

20 Scopus citations

Targeting renal cell carcinoma with a HIF-2 antagonist

Chen, W., Hill, H., Christie, A., Kim, M. S., Holloman, E., Pavia-Jimenez, A., Homayoun, F., Ma, Y., Patel, N., Yell, P., Hao, G., Yousuf, Q., Joyce, A., Pedrosa, I., Geiger, H., Zhang, H., Chang, J., Gardner, K. H., Bruick, R. K., Reeves, C. & 14 others, Hwang, T. H., Courtney, K., Frenkel, E., Sun, X., Zojwalla, N., Wong, T., Rizzi, J. P., Wallace, E. M., Josey, J. A., Xie, Y., Xie, X. J., Kapur, P., McKay, R. M. & Brugarolas, J., 2016, In : Nature. 539, 7627, p. 112-117 6 p.

Research output: Contribution to journalArticle

205 Scopus citations

The effect of erythropoietin on autologous stem cell-mediated bone regeneration

Nair, A. M., Tsai, Y. T., Shah, K. M., Shen, J., Weng, H., Zhou, J., Sun, X., Saxena, R., Borrelli, J. & Tang, L., Oct 1 2013, In : Biomaterials. 34, 30, p. 7364-7371 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

The effect of the amide substituent on the biodistribution and tolerance of lanthanide(iii) dota-tetraamide derivatives

Woods, M., Caravan, P., Geraldes, C. F. G. C., Greenfield, M. T., Kiefer, G. E., Lin, M., McMillan, K., Prata, M. I. M., Santos, A. C., Sun, X., Wang, J., Zhang, S., Zhao, P. & Sherry, A. D., Dec 1 2008, In : Investigative Radiology. 43, 12, p. 861-870 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Theranostic Nanoseeds for Efficacious Internal Radiation Therapy of Unresectable Solid Tumors

Moeendarbari, S., Tekade, R., Mulgaonkar, A., Christensen, P., Ramezani, S., Hassan, G., Jiang, R., Öz, O. K., Hao, Y. & Sun, X., Feb 8 2016, In : Scientific Reports. 6, 20614.

Research output: Contribution to journalArticle

31 Scopus citations

The Role of Cdk5 in Neuroendocrine Thyroid Cancer

Pozo, K., Castro-Rivera, E., Tan, C., Plattner, F., Schwach, G., Siegl, V., Meyer, D., Guo, A., Gundara, J., Mettlach, G., Richer, E., Guevara, J. A., Ning, L., Gupta, A., Hao, G., Tsai, L. H., Sun, X., Antich, P., Sidhu, S., Robinson, B. G. & 5 others, Chen, H., Nwariaku, F. E., Pfragner, R., Richardson, J. A. & Bibb, J. A., Oct 14 2013, In : Cancer Cell. 24, 4, p. 499-511 13 p.

Research output: Contribution to journalArticle

81 Scopus citations

The role of DAB2IP in androgen receptor activation during prostate cancer progression

Wu, K., Liu, J., Tseng, S. F., Gore, C., Ning, Z., Sharifi, N., Fazli, L., Gleave, M., Kapur, P., Xiao, G., Sun, X., Oz, O. K., Min, W., Alexandrakis, G., Yang, C. R., Hsieh, C. L., Wu, H. C., He, D., Xie, D. & Hsieh, J. T., Apr 10 2014, In : Oncogene. 33, 15, p. 1954-1963 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

The role of the size and number of polyethylene glycol chains in the biodistribution and tumor localization of triazine dendrimers

Lim, J., Guo, Y., Rostollan, C. L., Stanfield, J., Hsieh, J. T., Sun, X. & Simanek, E. E., Jul 1 2008, In : Molecular Pharmaceutics. 5, 4, p. 540-547 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

The Warburg effect and glucose-derived cancer theranostics

Tekade, R. K. & Sun, X., 2017, (Accepted/In press) In : Drug Discovery Today.

Research output: Contribution to journalArticle

38 Scopus citations

Three-dimensional maximum a posteriori (MAP) imaging with radiopharmaceuticals labeled with three Cu radionuclides

Ruangma, A., Bai, B., Lewis, J. S., Sun, X., Welch, M. J., Leahy, R. & Laforest, R., Feb 1 2006, In : Nuclear Medicine and Biology. 33, 2, p. 217-226 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Transplantation of mesenchymal stem cells from young donors delays aging in mice

Shen, J., Tsai, Y. T., Dimarco, N. M., Long, M. A., Sun, X. & Tang, L., Dec 1 2011, In : Scientific reports. 1, 67.

Research output: Contribution to journalArticle

61 Scopus citations

Trapping iron oxide into hollow gold nanoparticles

Huang, C., Jiang, J., Muangphat, C., Sun, X. & Hao, Y., Jan 1 2012, In : Nanoscale Research Letters. 7, p. 1-5 5 p., 43.

Research output: Contribution to journalArticle

1 Scopus citations

Trapping Iron Oxide into Hollow Gold Nanoparticles

Huang, C., Jiang, J., Muangphat, C., Sun, X. & Hao, Y., Jan 2011, In : Nanoscale Research Letters. 6, 1, p. 1-5 5 p., 43.

Research output: Contribution to journalArticle

11 Scopus citations

Tumor uptake of triazine dendrimers decorated with four, sixteen, and sixty-four PSMA-targeted ligands: Passive versus active tumor targeting

Lim, J., Guan, B., Nham, K., Hao, G., Sun, X. & Simanek, E. E., Sep 1 2019, In : Biomolecules. 9, 9, 421.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Upregulation of TRAG3 gene in urothelial carcinoma of the bladder

Karam, J. A., Huang, S., Fan, J., Stanfield, J., Schultz, R. A., Pong, R. C., Sun, X., Mason, R. P., Xie, X-J., Niu, G., Chen, X., Frenkel, E. P., Sagalowsky, A. I. & Hsieh, J-T., Jun 15 2011, In : International Journal of Cancer. 128, 12, p. 2823-2832 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Use of Fc-engineered antibodies as clearing agents to increase contrast during PET

Swiercz, R., Chiguru, S., Tahmasbi, A., Ramezani, S. M., Hao, G., Challa, D. K., Lewis, M. A., Kulkarni, P. V., Sun, X., Ober, R. J., Mason, R. P. & Ward, E. S., Jul 1 2014, In : Journal of Nuclear Medicine. 55, 7, p. 1204-1207 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

WE‐E‐108‐01: BEST IN PHYSICS (THERAPY) ‐ Radiotherapy Enhancement with a Novel Class of Hollow Nanoconstructs

Mao, W., Huang, C., Kearney, V., Song, K., Christensen, P., Sun, X., Hao, Y. & Solberg, T., 2013, In : Medical Physics. 40, 6, p. 488 1 p.

Research output: Contribution to journalArticle