Xiaofang Huo

  • 1097 Citations
  • 16 h-Index
20052020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 1097 Citations
  • 16 h-Index
  • 23 Article
  • 1 Editorial
  • 1 Review article
2020
2019

Acidic Bile Salts Induce Epithelial to Mesenchymal Transition via VEGF Signaling in Non-Neoplastic Barrett's Cells

Zhang, Q. D., Agoston, A. T., Pham, T. H., Zhang, W., Zhang, X., Huo, X., Peng, S., Bajpai, M., Das, K., Odze, R. D., Spechler, S. J. & Souza, R. F., Jan 1 2019, In : Gastroenterology. 156, 1, p. 130-144.e10

Research output: Contribution to journalArticle

6 Scopus citations
2018
14 Scopus citations

Selective inhibitory effects of zinc on cell proliferation in esophageal squamous cell carcinoma through Orai1

Choi, S., Cui, C., Luo, Y., Kim, S. H., Ko, J. K., Huo, X., Ma, J., Fu, L. W., Souza, R. F., Korichneva, I. & Pan, Z., Jan 1 2018, In : FASEB Journal. 32, 1, p. 404-416 13 p.

Research output: Contribution to journalArticle

13 Scopus citations
2016

Association of acute gastroesophageal reflux disease with esophageal histologic changes

Dunbar, K. B., Agoston, A. T., Odze, R. D., Huo, X., Pham, T. H., Cipher, D. J., Castell, D. O., Genta, R. M., Souza, R. F. & Spechler, S. J., May 17 2016, In : JAMA - Journal of the American Medical Association. 315, 19, p. 2104-2112 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Hypoxia-inducible factor-2α plays a role in mediating oesophagitis in GORD

Huo, X., Agoston, A. T., Dunbar, K. B., Cipher, D. J., Zhang, X., Yu, C., Cheng, E., Zhang, Q., Pham, T. H., Tambar, U. K., Bruick, R. K., Wang, D. H., Odze, R. D., Spechler, S. J. & Souza, R. F., Sep 30 2016, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

10 Scopus citations

In oesophageal squamous cells, nitric oxide causes S-nitrosylation of Akt and blocks SOX2 (sex determining region Y-box 2) expression

Asanuma, K., Huo, X., Agoston, A., Zhang, X., Yu, C., Cheng, E., Zhang, Q., Dunbar, K. B., Pham, T. H., Wang, D. H., Iijima, K., Shimosegawa, T., Odze, R. D., Spechler, S. J. & Souza, R. F., Sep 1 2016, In : Gut. 65, 9, p. 1416-1426 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
22 Scopus citations

NOD-Like Receptor Protein 3 Inflammasome Priming and Activation in Barrett's Epithelial Cells

Nadatani, Y., Huo, X., Zhang, X., Yu, C., Cheng, E., Zhang, Q., Dunbar, K. B., Theiss, A., Pham, T. H., Wang, D. H., Watanabe, T., Fujiwara, Y., Arakawa, T., Spechler, S. J. & Souza, R. F., Jul 1 2016, In : CMGH Cellular and Molecular Gastroenterology and Hepatology. 2, 4, p. 439-453 15 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

Mitochondrial STAT3 contributes to transformation of barrett’s epithelial cells that express oncogenic ras in a p53-independent fashion

Yu, C., Huo, X., Agoston, A. T., Zhang, X., Theiss, A. L., Cheng, E., Zhang, Q., Zaika, A., Pham, T. H., Wang, D. H., Lobie, P. E., Odze, R. D., Spechler, S. J. & Souza, R. F., Aug 5 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 3, p. G146-G161

Research output: Contribution to journalArticle

11 Scopus citations
2014

Autocrine VEGF signaling promotes proliferation of neoplastic barrett's epithelial cells through a PLC-dependent pathway

Zhang, Q. D., Yu, C., Peng, S., Xu, H., Wright, E., Zhang, X., Huo, X., Cheng, E., Pham, T. H., Asanuma, K., Hatanpaa, K. J., Rezai, D., Wang, D. H., Sarode, V. R., Melton, S. D., Genta, R. M., Spechler, S. J. & Souza, R. F., Feb 2014, In : Gastroenterology. 146, 2, p. 461-472.e6

Research output: Contribution to journalArticle

29 Scopus citations
24 Scopus citations
39 Scopus citations
2013

Acid burn or cytokine sizzle in the pathogenesis of heartburn?

Huo, X. & Souza, R. F., Mar 2013, In : Journal of Gastroenterology and Hepatology (Australia). 28, 3, p. 385-387 3 p.

Research output: Contribution to journalEditorial

5 Scopus citations
166 Scopus citations
2012

Omeprazole Blocks STAT6 Binding to the Eotaxin-3 Promoter in Eosinophilic Esophagitis Cells

Zhang, X., Cheng, E., Huo, X., Yu, C., Zhang, Q., Pham, T. H., Wang, D. H., Spechler, S. J. & Souza, R. F., Nov 21 2012, In : PloS one. 7, 11, e50037.

Research output: Contribution to journalArticle

130 Scopus citations
22 Scopus citations
2011
44 Scopus citations

Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κ{green}b activation in benign barrett's epithelial cells

Huo, X., Juergens, S., Zhang, X., Rezaei, D., Yu, C., Strauch, E. D., Wang, J. Y., Cheng, E., Meyer, F., Wang, D. H., Zhang, Q., Spechler, S. J. & Souza, R. F., Aug 1 2011, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 301, 2, p. G278-G286

Research output: Contribution to journalArticle

67 Scopus citations
2010

Acid and Bile Salt-Induced CDX2 Expression Differs in Esophageal Squamous Cells From Patients With and Without Barrett's Esophagus

Huo, X., Zhang, H. Y., Zhang, X. I., Lynch, J. P., Strauch, E. D., Wang, J. Y., Melton, S. D., Genta, R. M., Wang, D. H., Spechler, S. J. & Souza, R. F., Jul 2010, In : Gastroenterology. 139, 1, p. 194-203.e1

Research output: Contribution to journalArticle

79 Scopus citations

Malignant transformation of non-neoplastic Barrett's epithelial cells through well-defined genetic manipulations

Zhang, X., Yu, C., Wilson, K., Zhang, H. Y., Melton, S. D., Huo, X., Wang, D. H., Genta, R. M., Spechler, S. J. & Souza, R. F., Nov 1 2010, In : PloS one. 5, 9, p. 1-11 11 p., e13093.

Research output: Contribution to journalArticle

22 Scopus citations
2009

Gastroesophageal Reflux Might Cause Esophagitis Through a Cytokine-Mediated Mechanism Rather Than Caustic Acid Injury

Souza, R. F., Huo, X., Mittal, V., Schuler, C. M., Carmack, S. W., Zhang, H. Y., Zhang, X., Yu, C., Hormi-Carver, K., Genta, R. M. & Spechler, S. J., Nov 2009, In : Gastroenterology. 137, 5, p. 1776-1784 9 p.

Research output: Contribution to journalArticle

222 Scopus citations
2006

Differential expression changes in K562 cells during the hemin-induced erythroid differentiation and the phorbol myristate acetate (PMA)-induced megakaryocytic differentiation

Huo, X. F., Yu, J., Peng, H., Du, Z. W., Liu, X. L., Ma, Y. N., Zhang, X., Zhang, Y., Zhao, H. L. & Zhang, J. W., Nov 1 2006, In : Molecular and Cellular Biochemistry. 292, 1-2, p. 155-167 13 p.

Research output: Contribution to journalArticle

25 Scopus citations
2005

Annexin1 regulates the erythroid differentiation through ERK signaling pathway

Huo, X. F. & Zhang, J. W., Jun 17 2005, In : Biochemical and Biophysical Research Communications. 331, 4, p. 1346-1352 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Important roles of reversible acetylation in the function of hematopoietic transcription factors

Huo, X. & Zhang, J., Jan 1 2005, In : Journal of Cellular and Molecular Medicine. 9, 1, p. 103-112 10 p.

Research output: Contribution to journalReview article

33 Scopus citations