• 171 Citations
  • 6 h-Index
20022013
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Xin Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Protein Kinase Inhibitors Medicine & Life Sciences
Immediate-Early Genes Medicine & Life Sciences
Cyclic AMP-Dependent Protein Kinases Medicine & Life Sciences
Parathyroid Hormone Medicine & Life Sciences
Osteoblasts Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Protein Kinases Medicine & Life Sciences
Adrenergic Agonists Medicine & Life Sciences

Research Output 2002 2013

  • 171 Citations
  • 6 h-Index
  • 7 Article
  • 1 Chapter
6 Citations (Scopus)

Protein kinase inhibitor γ reciprocally regulates osteoblast and adipocyte differentiation by downregulating leukemia inhibitory factor

Chen, X., Hausman, B. S., Luo, G., Zhou, G., Murakami, S., Rubin, J. & Greenfield, E. M., Dec 1 2013, In : Stem Cells. 31, 12, p. 2789-2799 11 p.

Research output: Contribution to journalArticle

Leukemia Inhibitory Factor
Adipogenesis
Protein Kinase Inhibitors
Cyclic AMP-Dependent Protein Kinases
Osteoblasts

Use of siRNA and antisense knockdown to study regulation of PKA by PKI

Greenfield, E. M. & Chen, X., Dec 1 2010, Handbook of Cell Signaling, 2/e. Elsevier Inc., Vol. 2. p. 1569-1572 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Protein Kinase Inhibitors
Protein Kinases
Small Interfering RNA
Protein Kinase C
Nuclear Export Signals
22 Citations (Scopus)

Stimulation of macrophage TNFα production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-κB pathways but is independent of p38 and JNK

Beidelschies, M. A., Huang, H., Mcmullen, M. R., Smith, M. V., Islam, A. S., Goldberg, V. M., Chen, X., Nagy, L. E. & Greenfield, E. M., Dec 1 2008, In : Journal of Cellular Physiology. 217, 3, p. 652-666 15 p.

Research output: Contribution to journalArticle

Macrophages
Orthopedics
Endotoxins
Chemical activation
Wear of materials
12 Citations (Scopus)

Endogenous PKIγ limits the duration of the anti-apoptotic effects of pth and β-adrenergic agonists in osteoblasts

Chen, X., Song, I. H., Dennis, J. E. & Greenfield, E. M., May 1 2007, In : Journal of Bone and Mineral Research. 22, 5, p. 656-664 9 p.

Research output: Contribution to journalArticle

Adrenergic Agonists
Protein Kinase Inhibitors
Osteoblasts
Cyclic AMP-Dependent Protein Kinases
Osteoporosis
55 Citations (Scopus)

Lipopolysaccharide found in aseptic loosening of patients with inflammatory arthritis

Nalepka, J. L., Lee, M. J., Kraay, M. J., Marcus, R. E., Goldberg, V. M., Chen, X. & Greenfield, E. M., Oct 2006, In : Clinical orthopaedics and related research. 451, p. 229-235 7 p.

Research output: Contribution to journalArticle

Arthritis
Lipopolysaccharides
Endotoxins
Osteoarthritis
Infection