• 1403 Citations
  • 17 h-Index
19992019
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Fingerprint Dive into the research topics where Zhe Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 21 Similar Profiles
Rho Guanine Nucleotide Exchange Factors Medicine & Life Sciences
Chemical activation Chemical Compounds
GTP-Binding Proteins Medicine & Life Sciences
rho GTP-Binding Proteins Medicine & Life Sciences
GTP Phosphohydrolases Medicine & Life Sciences
GTPase-Activating Proteins Medicine & Life Sciences
Switches Chemical Compounds
Heterotrimeric GTP-Binding Proteins Medicine & Life Sciences

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Research Output 1999 2019

  • 1403 Citations
  • 17 h-Index
  • 27 Article
2 Citations (Scopus)

Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan

Li, F., Raczynska, J. E., Chen, Z. & Yu, H., Mar 19 2019, In : Cell Reports. 26, 12, p. 3336-3346.e4

Research output: Contribution to journalArticle

Open Access
Metalloproteases
Single-Stranded DNA
Chemical activation
DNA
Progeria
4 Citations (Scopus)

An isolated CLASP TOG domain suppresses microtubule catastrophe and promotes rescue

Majumdar, S., Kim, T., Chen, Z., Munyoki, S., Tso, S. C., Brautigam, C. A. & Rice, L. M., Jun 1 2018, In : Molecular Biology of the Cell. 29, 11, p. 1359-1375 17 p.

Research output: Contribution to journalArticle

Microtubules
Tubulin
Proteins
Chromosome Segregation
Point Mutation
4 Citations (Scopus)

Atypical activation of the G protein Gαq by the oncogenic mutation Q209P

Maziarz, M., Leyme, A., Marivin, A., Luebbers, A., Patel, P. P., Chen, Z., Sprang, S. R. & Garcia-Marcos, M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 51, p. 19586-19599 14 p.

Research output: Contribution to journalArticle

Gq-G11 GTP-Binding Protein alpha Subunits
GTP Phosphohydrolases
Bearings (structural)
Chemical activation
RGS Proteins
1 Citation (Scopus)

Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase

Chen, Z., Gutowski, S. & Sternweis, P. C., Apr 1 2018, In : Data in Brief. 17, p. 356-362 7 p.

Research output: Contribution to journalArticle

Rho Guanine Nucleotide Exchange Factors
GTP Phosphohydrolases
rho GTP-Binding Proteins
Manuscripts
Pleckstrin Homology Domains
7 Citations (Scopus)

Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity

Ye, R., Gordillo, R., Shao, M., Onodera, T., Chen, Z., Chen, S., Lin, X., SoRelle, J. A., Li, X., Tang, M., Keller, M. P., Kuliawat, R., Attie, A. D., Gupta, R. K., Holland, W. L., Beutler, B. A., Herz, J. & Scherer, P. E., Mar 1 2018, In : Journal of Clinical Investigation. 128, 3, p. 1178-1189 12 p.

Research output: Contribution to journalArticle

Low Density Lipoprotein Receptor-Related Protein-1
Lipid Metabolism
Obesity
Insulin
Diet