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Research Output 1990 2019

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Review article
2019
36 Citations (Scopus)

cGAS in action: Expanding roles in immunity and inflammation

Ablasser, A. & Chen, Z., Mar 8 2019, In : Science (New York, N.Y.). 363, 6431

Research output: Contribution to journalReview article

Immunity
Inflammation
DNA
Infection
Therapeutics
2018
7 Citations (Scopus)

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine

Carbone, M., Amelio, I., Affar, E. B., Brugarolas, J. B., Cannon-Albright, L. A., Cantley, L. C., Cavenee, W. K., Chen, Z., Croce, C. M., Andrea, A. D., Gandara, D., Giorgi, C., Jia, W., Lan, Q., Mak, T. W., Manley, J. L., Mikoshiba, K., Onuchic, J. N., Pass, H. I., Pinton, P. & 8 others, Prives, C., Rothman, N., Sebti, S. M., Turkson, J., Wu, X., Yang, H., Yu, H. & Melino, G., Nov 1 2018, In : Cell Death and Differentiation. 25, 11, p. 1885-1904 20 p.

Research output: Contribution to journalReview article

Gene-Environment Interaction
Precision Medicine
Carcinogenesis
Neoplasms
Intrinsic Factor
35 Citations (Scopus)

Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids

Tan, X., Sun, L., Chen, J. & Chen, Z. J., Sep 8 2018, In : Annual Review of Microbiology. 72, p. 447-478 32 p.

Research output: Contribution to journalReview article

Pattern Recognition Receptors
Nucleic Acids
Infection
RNA
Interferon Type I
105 Citations (Scopus)

The cGAS-cGAMP-STI NG pathway connects DNA damage to inflammation, senescence, and cancer

Li, T. & Chen, Z. J., May 1 2018, In : Journal of Experimental Medicine. 215, 5, p. 1287-1299 13 p.

Research output: Contribution to journalReview article

Sexually Transmitted Diseases
DNA Damage
Inflammation
DNA
Neoplasms
2016
353 Citations (Scopus)

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing

Chen, Q., Sun, L. & Chen, Z. J., Sep 20 2016, In : Nature Immunology. 17, 10, p. 1142-1149 8 p.

Research output: Contribution to journalReview article

DNA
GMP synthase (glutamine-hydrolyzing)
Second Messenger Systems
Innate Immunity
Nucleic Acids