Abstract
Benign prostatic hyperplasia (BPH) is a common cause of urinary outflow obstruction in aging men leading to lower urinary tract symptoms (LUTS). α1-Adrenoceptors (α1ARs) antagonists (blockers) have become a mainstay of LUTS treatment because they relax prostate smooth muscle and decrease urethral resistance, as well as relieving bladder LUTS symptoms. A review of key recent clinical trials suggests new insights into the role of specific α1AR subtypes in the treatment of LUTS.
Original language | English (US) |
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Pages (from-to) | 193-199 |
Number of pages | 7 |
Journal | International Journal of Urology |
Volume | 15 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2008 |
Keywords
- Adrenergic
- Adrenoceptor
- Alpha blockers
- BPH
- Benign prostatic hyperplasia
- Prostate
ASJC Scopus subject areas
- Urology