Abstract
In this issue of JEM, Du et al. (https://doi.org/10.1084/jem.20191115) report that enhancement of the β-catenin signaling by Wnt or EGF treatment increases the expression of PD-L1 in an AKT and β-catenin-dependent manner, and blocking the AKT pathway synergizes with anti-PD-1 in a glioblastoma model.
Original language | English (US) |
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Journal | The Journal of experimental medicine |
Volume | 217 |
Issue number | 11 |
DOIs |
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State | Published - Nov 2 2020 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology