TY - JOUR
T1 - 1,3-Oxazin-6-one Derivatives and Bohemamine-Type Pyrrolizidine Alkaloids from a Marine-Derived Streptomyces spinoverrucosus
AU - Fu, Peng
AU - La, Scott
AU - MacMillan, John B.
N1 - Publisher Copyright:
© 2015 The American Chemical Society and American Society of Pharmacognosy.
PY - 2016/3/25
Y1 - 2016/3/25
N2 - Two new 1,3-oxazin-6-one derivatives (1 and 2) and six new bohemamine-type pyrrolizidine alkaloids (3-8) were isolated from the marine-derived Streptomyces spinoverrucosus strain SNB-048. Their structures including the absolute configurations were fully elucidated on the basis of spectroscopic analysis, ECD spectra, quantum chemical calculations, and chemical methods. Compounds 1 and 2 possess a γ-lactam moiety and a 1,3-oxazin-6-one system.
AB - Two new 1,3-oxazin-6-one derivatives (1 and 2) and six new bohemamine-type pyrrolizidine alkaloids (3-8) were isolated from the marine-derived Streptomyces spinoverrucosus strain SNB-048. Their structures including the absolute configurations were fully elucidated on the basis of spectroscopic analysis, ECD spectra, quantum chemical calculations, and chemical methods. Compounds 1 and 2 possess a γ-lactam moiety and a 1,3-oxazin-6-one system.
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U2 - 10.1021/acs.jnatprod.5b00604
DO - 10.1021/acs.jnatprod.5b00604
M3 - Article
C2 - 26489038
AN - SCOPUS:84962094656
SN - 0163-3864
VL - 79
SP - 455
EP - 462
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 3
ER -