Previous NMR studies of intermediary metabolism have emphasized **3**1P NMR spectroscopy to monitor energy state of tissue and cells. Generation of these high energy phosphates depends on metabolism of carbon substrates through enzyme catalyzed reactions that are sensitive to physiological variables. Because **1**3C enriched substrates may be detected in tissue, flux of these substrates may in principle be measured by magnetization transfer techniques. We have compared two methods to measure flow through alanine aminotransferase in solution and in perfused hearts.
|Original language||English (US)|
|Title of host publication||Unknown Host Publication Title|
|Place of Publication||Zurich, Switz|
|Publisher||Univ Zurich, Dep of Physics|
|Number of pages||2|
|State||Published - 1984|
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